Reelin signalling pathway
Pathways in the Reelin signalling pathway SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Reelin signalling pathway | Reactome |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | DAB1 | DAB Adaptor Protein 1 | Protein Coding | 1 |
| 2 | FYN | FYN Proto-Oncogene, Src Family Tyrosine Kinase | Protein Coding | 1 |
| 3 | SH3KBP1 | SH3 Domain Containing Kinase Binding Protein 1 | Protein Coding | 1 |
| 4 | RELN | Reelin | Protein Coding | 1 |
| 5 | VLDLR | Very Low Density Lipoprotein Receptor | Protein Coding | 1 |
Disorders associated with Reelin signalling pathway SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Arthritis, sacroiliac | Enrichment | RELN | 3.43 |
| 2 | Immunodeficiency 61 | Enrichment | SH3KBP1 | 3.43 |
| 3 | Spinocerebellar ataxia 37 | Enrichment | DAB1 | 3.43 |
| 4 | Synovitis | Enrichment | RELN | 3.43 |
| 5 | Cerebellar hypoplasia | Enrichment | VLDLR | 3.43 |
| 6 | Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome | Enrichment | VLDLR | 3.13 |
| 7 | Arthritis | Enrichment | RELN | 3.13 |
| 8 | Epilepsy, familial temporal lobe, 7 | Enrichment | RELN | 2.96 |
| 9 | Kyphosis | Enrichment | RELN | 2.96 |
| 10 | Epilepsy with auditory features | Enrichment | RELN | 2.96 |
| 11 | Lissencephaly 2 | Enrichment | RELN | 2.73 |
| 12 | Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 1 | Enrichment | VLDLR | 2.66 |
| 13 | Lissencephaly | Enrichment | RELN | 2.11 |
| 14 | Scoliosis | Enrichment | RELN | 2.05 |
| 15 | Benign epilepsy with centrotemporal spikes | Enrichment | RELN | 1.82 |
| 16 | Centralopathic epilepsy | Enrichment | RELN | 1.80 |
| 17 | Spastic ataxia | Enrichment | DAB1 | 1.71 |
| 18 | Schizophrenia | Enrichment | RELN | 1.67 |
| 19 | Congenital nervous system abnormality | Enrichment | VLDLR | 1.41 |
| 20 | Nervous system disease | Enrichment | VLDLR | 1.41 |