Regucalcin in proximal tubule epithelial kidney cells

No Pathway Network information available for Regucalcin in proximal tubule epithelial kidney cells

Pathways in the Regucalcin in proximal tubule epithelial kidney cells SuperPath

#	Name	Source	Genes
1	Regucalcin in proximal tubule epithelial kidney cells	WikiPathways	ACTA2 AKT1 APAF1 BAK1 BAX BRAF CALCA CASP3 MAP3K5 MAPK1 MCU MTOR PTH RAF1 RGN SEC16B SMAD2 SMAD4 TGFB1 TGFBR1 TNFRSF1A TRPV5 (see all 22) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RGN	Regucalcin	Protein Coding	1
2	MAP3K5	Mitogen-Activated Protein Kinase Kinase Kinase 5	Protein Coding	1
3	CALCA	Calcitonin Related Polypeptide Alpha	Protein Coding	1
4	TGFBR1	Transforming Growth Factor Beta Receptor 1	Protein Coding	1
5	SEC16B	SEC16 Homolog B, Endoplasmic Reticulum Export Factor	Protein Coding	1
6	MCU	Mitochondrial Calcium Uniporter	Protein Coding	1
7	CASP3	Caspase 3	Protein Coding	1
8	TNFRSF1A	TNF Receptor Superfamily Member 1A	Protein Coding	1
9	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
10	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
11	ACTA2	Actin Alpha 2, Smooth Muscle	Protein Coding	1
12	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
13	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	1
14	BAK1	BCL2 Antagonist/Killer 1	Protein Coding	1
15	PTH	Parathyroid Hormone	Protein Coding	1
16	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
17	SMAD4	SMAD Family Member 4	Protein Coding	1
18	SMAD2	SMAD Family Member 2	Protein Coding	1
19	APAF1	Apoptotic Peptidase Activating Factor 1	Protein Coding	1
20	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	1
21	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
22	TRPV5	Transient Receptor Potential Cation Channel Subfamily V Member 5	Protein Coding	1

Disorders associated with Regucalcin in proximal tubule epithelial kidney cells SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	ACTA2, SMAD2, SMAD4, TGFBR1	6.17
2	Loeys-dietz syndrome 1	Enrichment	SMAD2, TGFBR1	5.12
3	Colorectal cancer	Enrichment	AKT1, BAX, BRAF, SMAD4	4.98
4	Noonan syndrome with multiple lentigines	Enrichment	BRAF, RAF1	4.82
5	Gallbladder cancer	Enrichment	BRAF, SMAD4	4.28
6	Pilomyxoid astrocytoma	Enrichment	BRAF, RAF1	4.28
7	Melanocytic nevus syndrome, congenital	Enrichment	BRAF, RAF1	4.16
8	Loeys-dietz syndrome	Enrichment	SMAD2, TGFBR1	4.05
9	Lung cancer susceptibility 3	Enrichment	ACTA2, BRAF	3.65
10	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF, RAF1	3.58
11	Noonan syndrome 1	Enrichment	BRAF, RAF1	3.21
12	Rasopathy	Enrichment	BRAF, RAF1	3.10
13	Lung cancer	Enrichment	ACTA2, BRAF	2.92
14	Periodic fever, familial, autosomal dominant	Enrichment	TNFRSF1A	2.79
15	Proteus syndrome	Enrichment	AKT1	2.79
16	Noonan syndrome 5	Enrichment	RAF1	2.79
17	Noonan syndrome 7	Enrichment	BRAF	2.79
18	Leopard syndrome 3	Enrichment	BRAF	2.79
19	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.79
20	Multiple self-healing squamous epithelioma	Enrichment	TGFBR1	2.79
21	Noonan syndrome 13	Enrichment	MAPK1	2.79
22	Lymphangioma	Enrichment	BRAF	2.79
23	Phace association	Enrichment	BRAF	2.79
24	Leopard syndrome 2	Enrichment	RAF1	2.79
25	Multiple sclerosis 5	Enrichment	TNFRSF1A	2.79
26	Cowden syndrome 6	Enrichment	AKT1	2.79
27	Loeys-dietz syndrome 6	Enrichment	SMAD2	2.79
28	Tnf receptor-associated periodic fever syndrome	Enrichment	TNFRSF1A	2.79
29	Trigonitis	Enrichment	RAF1	2.79
30	Congenital heart defects, multiple types, 8, with or without heterotaxy	Enrichment	SMAD2	2.79
31	Heritable thoracic aortic disease	Enrichment	SMAD4	2.79
32	Syringocystadenoma papilliferum	Enrichment	BRAF	2.79
33	Ganglioglioma	Enrichment	BRAF	2.79
34	Nongerminomatous germ cell tumor	Enrichment	BRAF	2.79
35	Phace syndrome	Enrichment	BRAF	2.79
36	Classic hairy cell leukemia	Enrichment	BRAF	2.79
37	Hypoparathyroidism, familial isolated, 1	Enrichment	PTH	2.49
38	Myhre syndrome	Enrichment	SMAD4	2.49
39	Camurati-engelmann disease 1	Enrichment	TGFB1	2.49
40	Pulmonic stenosis	Enrichment	BRAF	2.49
41	Loeys-dietz syndrome 2	Enrichment	TGFBR1	2.49
42	Aortic aneurysm, familial thoracic 2	Enrichment	ACTA2	2.49
43	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	2.49
44	Smooth muscle dysfunction syndrome	Enrichment	ACTA2	2.49
45	Aortic aneurysm, familial thoracic 6	Enrichment	ACTA2	2.49
46	Moyamoya disease 5	Enrichment	ACTA2	2.49
47	Cebalid syndrome	Enrichment	MTOR	2.49
48	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	2.49
49	Camurati-engelmann disease	Enrichment	TGFB1	2.49
50	Smith-kingsmore syndrome	Enrichment	MTOR	2.49
51	Intermittent hydrarthrosis	Enrichment	TNFRSF1A	2.49
52	Ataxia-telangiectasia	Enrichment	BRAF	2.31
53	Juvenile polyposis syndrome	Enrichment	SMAD4	2.31
54	Langerhans cell histiocytosis	Enrichment	BRAF	2.31
55	Tethered spinal cord syndrome	Enrichment	BRAF	2.31
56	Familial isolated hypoparathyroidism	Enrichment	PTH	2.31
57	T-cell acute lymphoblastic leukemia	Enrichment	BAX	2.31
58	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF	2.19
59	Thyroid cancer, nonmedullary, 1	Enrichment	BRAF	2.19
60	Autoimmune lymphoproliferative syndrome	Enrichment	ACTA2	2.19
61	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	2.19
62	Focal cortical dysplasia, type ii	Enrichment	MTOR	2.19
63	Cardiofaciocutaneous syndrome	Enrichment	BRAF	2.19
64	Aortic aneurysm	Enrichment	TGFBR1	2.19
65	Craniopharyngioma	Enrichment	BRAF	2.19
66	Newborn respiratory distress syndrome	Enrichment	BRAF	2.19
67	Primary hyperparathyroidism	Enrichment	PTH	2.19
68	Isolated focal cortical dysplasia type ii	Enrichment	MTOR	2.19
69	Dilated cardiomyopathy	Enrichment	BRAF, RAF1	2.13
70	Hemimegalencephaly	Enrichment	MTOR	2.09
71	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	SMAD4	2.09
72	Moyamoya disease 1	Enrichment	ACTA2	2.01
73	Wilms tumor 5	Enrichment	BRAF	2.01
74	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	2.01
75	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	2.01
76	Breast adenocarcinoma	Enrichment	AKT1	2.01
77	Classic ehlers-danlos syndrome	Enrichment	TGFBR1	2.01
78	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF	1.95
79	Renal cell carcinoma, papillary, 1	Enrichment	MTOR	1.95
80	Noonan syndrome 3	Enrichment	RAF1	1.95
81	Hereditary hemorrhagic telangiectasia	Enrichment	SMAD4	1.95
82	Follicular thyroid carcinoma	Enrichment	BRAF	1.95
83	Overgrowth syndrome	Enrichment	MTOR	1.95
84	Lymphoma, non-hodgkin, familial	Enrichment	BRAF	1.89
85	Cardiomyopathy, familial hypertrophic, 4	Enrichment	BRAF	1.84
86	Charge syndrome	Enrichment	TNFRSF1A	1.84
87	Primary hyperaldosteronism	Enrichment	BRAF	1.84
88	Ventricular septal defect	Enrichment	BRAF	1.84
89	Cowden syndrome	Enrichment	AKT1	1.84
90	Marfan syndrome	Enrichment	TGFBR1	1.79
91	Melanoma	Enrichment	BRAF	1.79
92	Pectus excavatum	Enrichment	TGFBR1	1.75
93	Lung non-small cell carcinoma	Enrichment	BRAF	1.75
94	Specific learning disability	Enrichment	MAPK1	1.75
95	Meningioma	Enrichment	AKT1	1.71
96	Lip and oral cavity carcinoma	Enrichment	BRAF	1.71
97	Multiple sclerosis	Enrichment	TNFRSF1A	1.65
98	Renal cell carcinoma, nonpapillary	Enrichment	MTOR	1.62
99	Wilms tumor 1	Enrichment	BRAF	1.62
100	Rare genetic intellectual disability	Enrichment	MTOR	1.62
101	Melanoma, cutaneous malignant 1	Enrichment	BRAF	1.56
102	Dandy-walker syndrome	Enrichment	BRAF	1.56
103	Heart, malformation of	Enrichment	MAPK1	1.54
104	Arteriovenous malformations of the brain	Enrichment	BRAF	1.52
105	Behcet syndrome	Enrichment	TNFRSF1A	1.52
106	Diffuse large b-cell lymphoma	Enrichment	BRAF	1.52
107	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	1.42
108	Autoinflammatory disease	Enrichment	TNFRSF1A	1.42
109	Pancreatic cancer	Enrichment	SMAD4	1.40
110	Differentiated thyroid carcinoma	Enrichment	BRAF	1.34
111	Cystic fibrosis	Enrichment	TGFB1	1.30
112	Connective tissue disease	Enrichment	ACTA2	1.30
113	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	1.28
114	Left ventricular noncompaction	Enrichment	RAF1	1.26
115	Gastric cancer	Enrichment	SMAD4	1.17
116	Hereditary breast carcinoma	Enrichment	AKT1	1.16
117	Thrombocytopenia	Enrichment	SMAD4	1.12
118	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	1.08
119	Myeloma, multiple	Enrichment	BRAF	1.06
120	Breast cancer	Enrichment	AKT1	0.94
121	Ovarian cancer	Enrichment	AKT1	0.82
122	Microcephaly	Enrichment	MAPK1	0.74
123	Inherited cancer-predisposing syndrome	Enrichment	SMAD4	0.71

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Regucalcin in proximal tubule epithelial kidney cells

Pathway Network for Regucalcin in proximal tubule epithelial kidney cells

Member Pathways for Regucalcin in proximal tubule epithelial kidney cells

Pathways in the Regucalcin in proximal tubule epithelial kidney cells SuperPath

Associated Genes for Regucalcin in proximal tubule epithelial kidney cells

Associated Disorders for Regucalcin in proximal tubule epithelial kidney cells

Disorders associated with Regucalcin in proximal tubule epithelial kidney cells SuperPath

STRING Interaction Network for Regucalcin in proximal tubule epithelial kidney cells

Sources for Regucalcin in proximal tubule epithelial kidney cells