Regulation of apoptosis by parathyroid hormone-related protein

No Pathway Network information available for Regulation of apoptosis by parathyroid hormone-related protein

Pathways in the Regulation of apoptosis by parathyroid hormone-related protein SuperPath

#	Name	Source	Genes
1	Regulation of apoptosis by parathyroid hormone-related protein	WikiPathways	AKT1 BAK1 BAX BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L12 BCL2L13 BCL2L14 BCL2L15 BCL2L2 BID BOK GSK3A GSK3B ITGA6 ITGB4 MCL1 MYC PIK3CG PTHLH (see all 22) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	MCL1	MCL1 Apoptosis Regulator, BCL2 Family Member	Protein Coding	1
2	BID	BH3 Interacting Domain Death Agonist	Protein Coding	1
3	BCL2L1	BCL2 Like 1	Protein Coding	1
4	BCL2A1	BCL2 Related Protein A1	Protein Coding	1
5	BCL2	BCL2 Apoptosis Regulator	Protein Coding	1
6	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	1
7	BAK1	BCL2 Antagonist/Killer 1	Protein Coding	1
8	PTHLH	Parathyroid Hormone Like Hormone	Protein Coding	1
9	PIK3CG	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma	Protein Coding	1
10	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	1
11	ITGB4	Integrin Subunit Beta 4	Protein Coding	1
12	ITGA6	Integrin Subunit Alpha 6	Protein Coding	1
13	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	1
14	GSK3A	Glycogen Synthase Kinase 3 Alpha	Protein Coding	1
15	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
16	BCL2L12	BCL2 Like 12	Protein Coding	1
17	BCL2L14	BCL2 Like 14	Protein Coding	1
18	BOK	BCL2 Family Apoptosis Regulator BOK	Protein Coding	1
19	BCL2L2	BCL2 Like 2	Protein Coding	1
20	BCL2L15	BCL2 Like 15	Protein Coding	1
21	BCL2L13	BCL2 Like 13	Protein Coding	1
22	BCL2L10	BCL2 Like 10	Protein Coding	1

Disorders associated with Regulation of apoptosis by parathyroid hormone-related protein SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL2, MYC	5.12
2	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGA6, ITGB4	4.43
3	Junctional epidermolysis bullosa	Enrichment	ITGA6, ITGB4	4.05
4	Proteus syndrome	Enrichment	AKT1	2.79
5	Cowden syndrome 6	Enrichment	AKT1	2.79
6	Brachydactyly, type e2	Enrichment	PTHLH	2.79
7	Immunodeficiency 97 with autoinflammation	Enrichment	PIK3CG	2.79
8	Burkitt lymphoma	Enrichment	MYC	2.49
9	Epidermolysis bullosa, junctional 5a, intermediate	Enrichment	ITGB4	2.49
10	Intravascular large b-cell lymphoma	Enrichment	BCL2	2.49
11	Localized junctional epidermolysis bullosa, non-herlitz type	Enrichment	ITGB4	2.49
12	Brachydactyly, type e1	Enrichment	PTHLH	2.31
13	Epidermolysis bullosa, junctional 6, with pyloric atresia	Enrichment	ITGA6	2.31
14	T-cell acute lymphoblastic leukemia	Enrichment	BAX	2.31
15	Epidermolysis bullosa simplex 5c, with pyloric atresia	Enrichment	ITGB4	2.19
16	Epidermolysis bullosa simplex 1c, localized	Enrichment	ITGB4	2.09
17	Follicular lymphoma	Enrichment	BCL2	2.09
18	Epidermolysis bullosa	Enrichment	ITGA6	2.09
19	Aplasia cutis congenita	Enrichment	ITGB4	2.09
20	Colorectal cancer	Enrichment	AKT1, BAX	2.06
21	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	ITGB4	2.01
22	Junctional epidermolysis bullosa non-herlitz type	Enrichment	ITGB4	2.01
23	Breast adenocarcinoma	Enrichment	AKT1	2.01
24	Epidermolysis bullosa simplex	Enrichment	ITGB4	1.95
25	Cowden syndrome	Enrichment	AKT1	1.84
26	Meningioma	Enrichment	AKT1	1.71
27	Multiple sclerosis	Enrichment	ITGB4	1.65
28	Skin disease	Enrichment	ITGB4	1.45
29	Precursor t-cell acute lymphoblastic leukemia	Enrichment	MYC	1.44
30	Hereditary breast carcinoma	Enrichment	AKT1	1.16
31	Breast cancer	Enrichment	AKT1	0.94
32	Ovarian cancer	Enrichment	AKT1	0.82

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Regulation of apoptosis by parathyroid hormone-related protein

Pathway Network for Regulation of apoptosis by parathyroid hormone-related protein

Member Pathways for Regulation of apoptosis by parathyroid hormone-related protein

Pathways in the Regulation of apoptosis by parathyroid hormone-related protein SuperPath

Associated Genes for Regulation of apoptosis by parathyroid hormone-related protein

Associated Disorders for Regulation of apoptosis by parathyroid hormone-related protein

Disorders associated with Regulation of apoptosis by parathyroid hormone-related protein SuperPath

STRING Interaction Network for Regulation of apoptosis by parathyroid hormone-related protein

Sources for Regulation of apoptosis by parathyroid hormone-related protein