Regulation of CDH11 Expression and Function

Pathway network for the Regulation of CDH11 Expression and Function SuperPath

Sources:

Reactome

Pathways in the Regulation of CDH11 Expression and Function SuperPath

#	Name	Source	Genes
1	Regulation of CDH11 Expression and Function	Reactome	ADAM19 ADAM33 AGO1 AGO2 AGO3 AGO4 AMOT ANGPTL4 BHLHE22 CDH11 CDH24 CDH8 CTNNA1 CTNNB1 CTNND1 FOXF1 HEYL HOXC8 ILF3 JUP MOV10 PRDM8 SNAI1 SP1 TNRC6A TNRC6B TNRC6C ZEB2 (see all 28) (see less)
2	Regulation of Expression and Function of Type II Classical Cadherins	Reactome	ADAM19 ADAM33 AGO1 AGO2 AGO3 AGO4 AMOT ANGPTL4 BHLHE22 CDH11 CDH19 CDH24 CDH8 CTNNA1 CTNNB1 CTNND1 FOXF1 HEYL HOXC8 ILF3 JUP MOV10 PRDM8 SNAI1 SOX10 SP1 TNRC6A TNRC6B TNRC6C ZC3H12A ZEB2 (see all 31) (see less)
3	Regulation of CDH11 function	Reactome	ADAM19 ADAM33 AMOT ANGPTL4 CDH11 CDH24 CDH8 CTNNA1 CTNNB1 CTNND1 JUP (see all 11) (see less)
4	Regulation of CDH11 mRNA translation by microRNAs	Reactome	AGO1 AGO2 AGO3 AGO4 CDH11 MOV10 TNRC6A TNRC6B TNRC6C (see all 9) (see less)
5	Regulation of CDH11 gene transcription	Reactome	BHLHE22 FOXF1 HEYL HOXC8 ILF3 PRDM8 SNAI1 SP1 ZEB2 (see all 9) (see less)
6	Regulation of CDH19 Expression and Function	Reactome	CDH19 CTNNA1 CTNNB1 CTNND1 JUP SOX10 ZC3H12A (see all 7) (see less)
7	CDH11 homotypic and heterotypic interactions	Reactome	CDH11 CDH24 CDH8 CTNNA1 CTNNB1 CTNND1 JUP (see all 7) (see less)

Gene overlap in member pathways for Regulation of CDH11 Expression and Function SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CDH11	Cadherin 11	Protein Coding	5
2	CTNNA1	Catenin Alpha 1	Protein Coding	5
3	CTNNB1	Catenin Beta 1	Protein Coding	5
4	CTNND1	Catenin Delta 1	Protein Coding	5
5	JUP	Junction Plakoglobin	Protein Coding	5
6	CDH8	Cadherin 8	Protein Coding	4
7	CDH24	Cadherin 24	Protein Coding	4
8	AMOT	Angiomotin	Protein Coding	3
9	AGO3	Argonaute RISC Catalytic Component 3	Protein Coding	3
10	AGO4	Argonaute RISC Component 4	Protein Coding	3
11	FOXF1	Forkhead Box F1	Protein Coding	3
12	TNRC6B	Trinucleotide Repeat Containing Adaptor 6B	Protein Coding	3
13	HEYL	Hes Related Family BHLH Transcription Factor With YRPW Motif Like	Protein Coding	3
14	AGO1	Argonaute RISC Component 1	Protein Coding	3
15	AGO2	Argonaute RISC Catalytic Component 2	Protein Coding	3
16	BHLHE22	Basic Helix-Loop-Helix Family Member E22	Protein Coding	3
17	TNRC6A	Trinucleotide Repeat Containing Adaptor 6A	Protein Coding	3
18	HOXC8	Homeobox C8	Protein Coding	3
19	ILF3	Interleukin Enhancer Binding Factor 3	Protein Coding	3
20	MOV10	Mov10 RNA Helicase	Protein Coding	3
21	ANGPTL4	Angiopoietin Like 4	Protein Coding	3
22	PRDM8	PR/SET Domain 8	Protein Coding	3
23	TNRC6C	Trinucleotide Repeat Containing Adaptor 6C	Protein Coding	3
24	SNAI1	Snail Family Transcriptional Repressor 1	Protein Coding	3
25	SP1	Sp1 Transcription Factor	Protein Coding	3
26	ADAM33	ADAM Metallopeptidase Domain 33	Protein Coding	3
27	ADAM19	ADAM Metallopeptidase Domain 19	Protein Coding	3
28	ZEB2	Zinc Finger E-Box Binding Homeobox 2	Protein Coding	3
29	CDH19	Cadherin 19	Protein Coding	2
30	SOX10	SRY-Box Transcription Factor 10	Protein Coding	2
31	ZC3H12A	Zinc Finger CCCH-Type Containing 12A	Protein Coding	2

Disorders associated with Regulation of CDH11 Expression and Function SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Complex neurodevelopmental disorder	Enrichment	AGO1, AGO2, TNRC6B	4.22
2	Arrhythmogenic right ventricular dysplasia, familial, 12	Enrichment	JUP	3.29
3	Macular dystrophy, patterned, 2	Enrichment	CTNNA1	3.29
4	Naxos disease	Enrichment	JUP	3.29
5	Adenoid ameloblastoma	Enrichment	CTNNB1	3.29
6	Microcystic stromal tumor	Enrichment	CTNNB1	3.29
7	Elsahy-waters syndrome	Enrichment	CDH11	3.29
8	Teebi hypertelorism syndrome 2	Enrichment	CDH11	3.29
9	Global developmental delay with speech and behavioral abnormalities	Enrichment	TNRC6B	3.18
10	Epilepsy, familial adult myoclonic, 6	Enrichment	TNRC6A	3.18
11	Progressive myoclonus epilepsy 10	Enrichment	PRDM8	3.18
12	Epilepsy, progressive myoclonic, 10	Enrichment	PRDM8	3.18
13	Atresia of urethra	Enrichment	FOXF1	3.18
14	Plasma triglyceride level quantitative trait locus	Enrichment	ANGPTL4	3.09
15	Colorectal cancer	Enrichment	CTNNA1, CTNNB1	3.08
16	Blepharocheilodontic syndrome 1	Enrichment	CTNND1	2.99
17	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	2.99
18	Waardenburg syndrome, type 4c	Enrichment	SOX10	2.99
19	Blepharocheilodontic syndrome 2	Enrichment	CTNND1	2.99
20	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	2.99
21	Peripheral demyelinating neuropathy, central dysmyelination, waardenburg syndrome, and hirschsprung disease	Enrichment	SOX10	2.99
22	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	2.99
23	Teratoma	Enrichment	CTNNB1	2.99
24	Premature ovarian failure 3	Enrichment	AGO2	2.88
25	Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures	Enrichment	AGO1	2.88
26	Mowat-wilson syndrome	Enrichment	ZEB2	2.88
27	Pyloric stenosis, infantile hypertrophic, 5	Enrichment	FOXF1	2.88
28	Idiopathic/heritable pulmonary arterial hypertension	Enrichment	FOXF1	2.88
29	Desmoid disease, hereditary	Enrichment	CTNNB1	2.81
30	Waardenburg syndrome, type 2a	Enrichment	SOX10	2.81
31	Epidermolysis bullosa, lethal acantholytic	Enrichment	JUP	2.81
32	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	2.81
33	Anus, imperforate	Enrichment	CTNNB1	2.81
34	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	2.81
35	Desmoid tumor	Enrichment	CTNNB1	2.81
36	Butterfly-shaped pigment dystrophy	Enrichment	CTNNA1	2.81
37	Lessel-kreienkamp syndrome	Enrichment	AGO2	2.70
38	Alveolar capillary dysplasia with misalignment of pulmonary veins	Enrichment	FOXF1	2.70
39	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CTNNA1	2.69
40	Polyposis syndrome, hereditary mixed, 1	Enrichment	CTNNA1	2.69
41	Pilomatrixoma	Enrichment	CTNNB1	2.69
42	Alazami syndrome	Enrichment	CTNNB1	2.69
43	Craniopharyngioma	Enrichment	CTNNB1	2.69
44	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	2.59
45	Hypogonadotropic hypogonadism 1 with or without anosmia	Enrichment	SOX10	2.59
46	Vacterl association	Enrichment	FOXF1	2.58
47	Weyers acrofacial dysostosis	Enrichment	CTNNB1	2.51
48	Waardenburg syndrome, type 4a	Enrichment	SOX10	2.51
49	Adrenocortical carcinoma	Enrichment	CTNNB1	2.51
50	Waardenburg syndrome	Enrichment	SOX10	2.51
51	Cleft lip with or without cleft palate	Enrichment	CTNND1	2.51
52	Vater/vacterl association	Enrichment	FOXF1	2.48
53	Waardenburg syndrome, type 1	Enrichment	SOX10	2.44
54	Waardenburg syndrome, type 2e	Enrichment	SOX10	2.44
55	Gallbladder cancer	Enrichment	CTNNB1	2.44
56	Exudative vitreoretinopathy	Enrichment	CTNNB1	2.38
57	Megacolon	Enrichment	ZEB2	2.33
58	Adult hepatocellular carcinoma	Enrichment	CTNNB1	2.33
59	Melanocytic nevus syndrome, congenital	Enrichment	ZEB2	2.28
60	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	TNRC6B	2.22
61	Ventricular septal defect	Enrichment	FOXF1	2.22
62	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	JUP	2.21
63	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	JUP	2.21
64	Medulloblastoma	Enrichment	CTNNB1	2.14
65	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	JUP	2.14
66	Wolff-parkinson-white syndrome	Enrichment	JUP	2.08
67	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	JUP	2.08
68	Polycystic liver disease	Enrichment	CTNNB1	2.06
69	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	2.06
70	Craniosynostosis	Enrichment	CTNNA1	1.99
71	Hepatoblastoma	Enrichment	CTNNB1	1.97
72	Hepatocellular carcinoma	Enrichment	CTNNB1	1.95
73	Kallmann syndrome	Enrichment	SOX10	1.93
74	Bladder cancer	Enrichment	CTNNB1	1.83
75	Hirschsprung disease 1	Enrichment	SOX10	1.83
76	Congenital nervous system abnormality	Enrichment	CTNNB1, ZEB2	1.70
77	Nervous system disease	Enrichment	CTNNB1, ZEB2	1.70
78	Hereditary breast ovarian cancer syndrome	Enrichment	CTNNA1	1.55
79	Rare genetic deafness	Enrichment	SOX10	1.40
80	Dilated cardiomyopathy	Enrichment	JUP	1.39
81	Ovarian cancer	Enrichment	CTNNB1	1.29
82	Microcephaly	Enrichment	CTNNB1	1.21
83	Inherited cancer-predisposing syndrome	Enrichment	CTNNA1	1.18
84	Autism spectrum disorder	Enrichment	TNRC6B	1.15
85	Hereditary retinal dystrophy	Enrichment	CTNNA1	0.85
86	Fundus dystrophy	Enrichment	CTNNA1	0.85

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Regulation of CDH11 Expression and Function

Pathway Network for Regulation of CDH11 Expression and Function

Pathway network for the Regulation of CDH11 Expression and Function SuperPath

Member Pathways for Regulation of CDH11 Expression and Function

Pathways in the Regulation of CDH11 Expression and Function SuperPath

Gene overlap in member pathways for Regulation of CDH11 Expression and Function SuperPath

Associated Genes for Regulation of CDH11 Expression and Function

Associated Disorders for Regulation of CDH11 Expression and Function

Disorders associated with Regulation of CDH11 Expression and Function SuperPath

STRING Interaction Network for Regulation of CDH11 Expression and Function

Sources for Regulation of CDH11 Expression and Function