Regulation of nuclear beta catenin signaling and target gene transcription

No Pathway Network information available for Regulation of nuclear beta catenin signaling and target gene transcription

Pathways in the Regulation of nuclear beta catenin signaling and target gene transcription SuperPath

#	Name	Source	Genes
1	Regulation of nuclear beta catenin signaling and target gene transcription	PubChem	ADCY7 APC AR AXIN2 BCL9 BTRC CACNA1G CAMK4 CBY1 CCN1 CCND1 CCND2 CDH1 CDKN2A CDX1 CDX4 CHD8 CTBP1 CTNNB1 CTNNBIP1 CUL1 CXCL8 DKK1 DKK4 DVL3 EP300 FGF4 HBP1 HDAC1 ID2 IGF2BP1 INCENP JUN KCNIP4 KLF4 KRT1 LEF1 MDFIC MED12 MITF MMP2 MMP9 MT-CO2 MYC MYF5 MYOG NCOA2 NEUROG1 PITX2 RUVBL2 SALL4 SFN SKP1 SMARCA4 SNAI2 SP5 TBL1X TBL1XR1 TBXT TCF4 TCF7 TCF7L1 TCF7L2 TERT TLE1 TLE2 TLE4 TLE5 TNIK TRRAP VCAN XPO1 ZCCHC12 (see all 73) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	KCNIP4	Potassium Voltage-Gated Channel Interacting Protein 4	Protein Coding	1
2	CDX1	Caudal Type Homeobox 1	Protein Coding	1
3	NEUROG1	Neurogenin 1	Protein Coding	1
4	MDFIC	MyoD Family Inhibitor Domain Containing	Protein Coding	1
5	KRT1	Keratin 1	Protein Coding	1
6	MYOG	Myogenin	Protein Coding	1
7	MYF5	Myogenic Factor 5	Protein Coding	1
8	ZCCHC12	Zinc Finger CCHC-Type Containing 12	Protein Coding	1
9	CDX4	Caudal Type Homeobox 4	Protein Coding	1
10	SP5	Sp5 Transcription Factor	Protein Coding	1
11	DVL3	Dishevelled Segment Polarity Protein 3	Protein Coding	1
12	TNIK	TRAF2 And NCK Interacting Kinase	Protein Coding	1
13	BCL9	BCL9 Transcription Coactivator	Protein Coding	1
14	HBP1	HMG-Box Transcription Factor 1	Protein Coding	1
15	VCAN	Versican	Protein Coding	1
16	ID2	Inhibitor Of DNA Binding 2	Protein Coding	1
17	DKK1	Dickkopf Wnt Signaling Pathway Inhibitor 1	Protein Coding	1
18	CCN1	Cellular Communication Network Factor 1	Protein Coding	1
19	DKK4	Dickkopf Wnt Signaling Pathway Inhibitor 4	Protein Coding	1
20	ADCY7	Adenylate Cyclase 7	Protein Coding	1
21	TCF7	Transcription Factor 7	Protein Coding	1
22	TCF4	Transcription Factor 4	Protein Coding	1
23	CACNA1G	Calcium Voltage-Gated Channel Subunit Alpha1 G	Protein Coding	1
24	TCF7L1	Transcription Factor 7 Like 1	Protein Coding	1
25	FGF4	Fibroblast Growth Factor 4	Protein Coding	1
26	TCF7L2	Transcription Factor 7 Like 2	Protein Coding	1
27	TBXT	T-Box Transcription Factor T	Protein Coding	1
28	LEF1	Lymphoid Enhancer Binding Factor 1	Protein Coding	1
29	PITX2	Paired Like Homeodomain 2	Protein Coding	1
30	MITF	Melanocyte Inducing Transcription Factor	Protein Coding	1
31	RUVBL2	RuvB Like AAA ATPase 2	Protein Coding	1
32	CCND2	Cyclin D2	Protein Coding	1
33	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	1
34	INCENP	Inner Centromere Protein	Protein Coding	1
35	AR	Androgen Receptor	Protein Coding	1
36	IGF2BP1	Insulin Like Growth Factor 2 MRNA Binding Protein 1	Protein Coding	1
37	CBY1	Chibby 1, Beta Catenin Antagonist	Protein Coding	1
38	CHD8	Chromodomain Helicase DNA Binding Protein 8	Protein Coding	1
39	TRRAP	Transformation/Transcription Domain Associated Protein	Protein Coding	1
40	TERT	Telomerase Reverse Transcriptase	Protein Coding	1
41	CTNNBIP1	Catenin Beta Interacting Protein 1	Protein Coding	1
42	AXIN2	Axin 2	Protein Coding	1
43	TLE2	TLE Family Member 2, Transcriptional Corepressor	Protein Coding	1
44	BTRC	Beta-Transducin Repeat Containing E3 Ubiquitin Protein Ligase	Protein Coding	1
45	TLE4	TLE Family Member 4, Transcriptional Corepressor	Protein Coding	1
46	TLE5	TLE Family Member 5, Transcriptional Modulator	Protein Coding	1
47	CCND1	Cyclin D1	Protein Coding	1
48	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	1
49	XPO1	Exportin 1	Protein Coding	1
50	APC	APC Regulator Of Wnt Signaling Pathway	Protein Coding	1
51	MT-CO2	Mitochondrially Encoded Cytochrome C Oxidase II	Protein Coding	1
52	MMP2	Matrix Metallopeptidase 2	Protein Coding	1
53	TLE1	TLE Family Member 1, Transcriptional Corepressor	Protein Coding	1
54	SNAI2	Snail Family Transcriptional Repressor 2	Protein Coding	1
55	CTNNB1	Catenin Beta 1	Protein Coding	1
56	SMARCA4	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 4	Protein Coding	1
57	CTBP1	C-Terminal Binding Protein 1	Protein Coding	1
58	CDH1	Cadherin 1	Protein Coding	1
59	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
60	SALL4	Spalt Like Transcription Factor 4	Protein Coding	1
61	KLF4	KLF Transcription Factor 4	Protein Coding	1
62	MED12	Mediator Complex Subunit 12	Protein Coding	1
63	NCOA2	Nuclear Receptor Coactivator 2	Protein Coding	1
64	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
65	TBL1X	Transducin Beta Like 1 X-Linked	Protein Coding	1
66	CAMK4	Calcium/Calmodulin Dependent Protein Kinase IV	Protein Coding	1
67	TBL1XR1	TBL1X/Y Related 1	Protein Coding	1
68	SFN	Stratifin	Protein Coding	1
69	SKP1	S-Phase Kinase Associated Protein 1	Protein Coding	1
70	CUL1	Cullin 1	Protein Coding	1
71	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	1
72	HDAC1	Histone Deacetylase 1	Protein Coding	1
73	MMP9	Matrix Metallopeptidase 9	Protein Coding	1

Disorders associated with Regulation of nuclear beta catenin signaling and target gene transcription SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Adrenocortical carcinoma	Enrichment	CDKN2A, CTNNB1, TERT	5.53
2	Colorectal cancer	Enrichment	APC, AXIN2, CCND1, CDH1, CTNNB1, EP300	5.15
3	Ovarian cancer	Enrichment	APC, AR, AXIN2, CDH1, CDKN2A, CTNNB1	4.78
4	Inherited cancer-predisposing syndrome	Enrichment	APC, AXIN2, CDH1, CDKN2A, MITF, SMARCA4	4.12
5	Desmoid disease, hereditary	Enrichment	APC, CTNNB1	4.07
6	Anus, imperforate	Enrichment	CTNNB1, MED12	4.07
7	Desmoid tumor	Enrichment	APC, CTNNB1	4.07
8	Melanoma, cutaneous malignant 1	Enrichment	CDKN2A, MITF, TERT	4.02
9	Craniopharyngioma	Enrichment	APC, CTNNB1	3.77
10	Hepatoblastoma	Enrichment	APC, CTNNB1, TERT	3.73
11	Hepatocellular carcinoma	Enrichment	APC, CTNNB1, TERT	3.67
12	Bladder cancer	Enrichment	CDKN2A, CTNNB1, TERT	3.31
13	Waardenburg syndrome, type 2e	Enrichment	MITF, SNAI2	3.23
14	Melanoma	Enrichment	CDKN2A, MITF	2.90
15	Gastric cancer	Enrichment	APC, CDH1, CDKN2A	2.80
16	Medulloblastoma	Enrichment	APC, CTNNB1	2.60
17	Rare genetic intellectual disability	Enrichment	CHD8, EP300	2.54
18	Microcephaly	Enrichment	CTNNB1, EP300, MED12, TCF4	2.36
19	Ichthyosis hystrix, curth-macklin type	Enrichment	KRT1	2.27
20	Chiari malformation type i	Enrichment	DKK1	2.27
21	Axenfeld-rieger syndrome, type 1	Enrichment	PITX2	2.27
22	Prostate cancer, hereditary, x-linked 3	Enrichment	AR	2.27
23	Androgen insensitivity, partial	Enrichment	AR	2.27
24	Palmoplantar keratoderma, nonepidermolytic	Enrichment	KRT1	2.27
25	Hypothyroidism, congenital, nongoitrous, 8	Enrichment	TBL1X	2.27
26	Oligodontia-colorectal cancer syndrome	Enrichment	AXIN2	2.27
27	Heterochromia iridis	Enrichment	MITF	2.27
28	Ivic syndrome	Enrichment	SALL4	2.27
29	Tietz albinism-deafness syndrome	Enrichment	MITF	2.27
30	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3	Enrichment	CCND2	2.27
31	Anterior segment dysgenesis 4	Enrichment	PITX2	2.27
32	Sacral agenesis with vertebral anomalies	Enrichment	TBXT	2.27
33	Ring dermoid of cornea	Enrichment	PITX2	2.27
34	Ectodermal dysplasia 17 with or without limb malformations	Enrichment	LEF1	2.27
35	Ichthyosis, annular epidermolytic, 2	Enrichment	KRT1	2.27
36	Intellectual developmental disorder, autosomal recessive 54	Enrichment	TNIK	2.27
37	Coloboma, osteopetrosis, microphthalmia, macrocephaly, albinism, and deafness	Enrichment	MITF	2.27
38	Keratosis palmoplantaris striata iii	Enrichment	KRT1	2.27
39	Lymphatic malformation 12	Enrichment	MDFIC	2.27
40	Ophthalmoplegia, external, with rib and vertebral anomalies	Enrichment	MYF5	2.27
41	Spinocerebellar ataxia 42	Enrichment	CACNA1G	2.27
42	Corneal dystrophy, fuchs endothelial, 3	Enrichment	TCF4	2.27
43	Smarca4-deficient sarcoma of thorax	Enrichment	SMARCA4	2.27
44	Ovarian small cell carcinoma	Enrichment	SMARCA4	2.27
45	Deafness, autosomal dominant 75	Enrichment	TRRAP	2.27
46	Spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits	Enrichment	CACNA1G	2.27
47	Developmental delay with or without dysmorphic facies and autism	Enrichment	TRRAP	2.27
48	Autosomal recessive dyskeratosis congenita 4	Enrichment	TERT	2.27
49	Cranial dysinnervation disorder, congenital, with absent corneal reflex and developmental delay	Enrichment	NEUROG1	2.27
50	Adenoid ameloblastoma	Enrichment	CTNNB1	2.27
51	Cdkn2a cancer predisposition	Enrichment	CDKN2A	2.27
52	Short-rib thoracic dysplasia 22 without polydactyly	Enrichment	FGF4	2.27
53	Palmoplantar keratoderma, epidermolytic, 2	Enrichment	KRT1	2.27
54	Sacral agenesis-abnormal ossification of the vertebral bodies-persistent notochordal canal syndrome	Enrichment	TBXT	2.27
55	Breast lobular carcinoma	Enrichment	CDH1	2.27
56	Familial adenomatous polyposis	Enrichment	APC	2.27
57	Complete androgen insensitivity syndrome	Enrichment	AR	2.27
58	Gardner syndrome	Enrichment	APC	2.27
59	Sall4-related disorders	Enrichment	SALL4	2.27
60	5q22 microdeletion syndrome	Enrichment	APC	2.27
61	Attenuated familial adenomatous polyposis	Enrichment	APC	2.27
62	Microcystic stromal tumor	Enrichment	CTNNB1	2.27
63	Precursor t-cell acute lymphoblastic leukemia	Enrichment	CDKN2A, MYC	2.17
64	Breast cancer	Enrichment	APC, CDH1, JUN	2.12
65	Prostate cancer	Enrichment	AR, CDH1	1.98
66	Ectrodactyly and ectodermal dysplasia without cleft lip/palate	Enrichment	LEF1	1.97
67	Blepharocheilodontic syndrome 1	Enrichment	CDH1	1.97
68	Melanoma-astrocytoma syndrome	Enrichment	CDKN2A	1.97
69	Burkitt lymphoma	Enrichment	MYC	1.97
70	Wagner vitreoretinopathy	Enrichment	VCAN	1.97
71	Spinal and bulbar muscular atrophy, x-linked 1	Enrichment	AR	1.97
72	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.97
73	Hardikar syndrome	Enrichment	MED12	1.97
74	Opitz-kaveggia syndrome	Enrichment	MED12	1.97
75	Axenfeld-rieger anomaly with partially absent eye muscles, distinctive face, hydrocephaly, and skeletal abnormalities	Enrichment	PITX2	1.97
76	Rhabdoid tumor predisposition syndrome 2	Enrichment	SMARCA4	1.97
77	Keratoderma, palmoplantar, with nail dystrophy and hereditary motor-sensory neuropathy	Enrichment	KRT1	1.97
78	Atrial fibrillation, familial, 1	Enrichment	PITX2	1.97
79	Piebald trait	Enrichment	SNAI2	1.97
80	Duane-radial ray syndrome	Enrichment	SALL4	1.97
81	Melanoma, cutaneous malignant 2	Enrichment	CDKN2A	1.97
82	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 1	Enrichment	TERT	1.97
83	Robinow syndrome, autosomal dominant 3	Enrichment	DVL3	1.97
84	Hypotonia, ataxia, developmental delay, and tooth enamel defect syndrome	Enrichment	CTBP1	1.97
85	46,xy sex reversal 1	Enrichment	AR	1.97
86	Androgen insensitivity syndrome	Enrichment	AR	1.97
87	Ohdo syndrome, x-linked	Enrichment	MED12	1.97
88	Menke-hennekam syndrome 2	Enrichment	EP300	1.97
89	Melanoma, cutaneous malignant 8	Enrichment	MITF	1.97
90	Hypospadias 1, x-linked	Enrichment	AR	1.97
91	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	1.97
92	Rhabdoid tumor predisposition syndrome	Enrichment	SMARCA4	1.97
93	Split hand-foot malformation	Enrichment	LEF1	1.97
94	Melanoma-pancreatic cancer syndrome	Enrichment	CDKN2A	1.97
95	Papillary renal cell carcinoma	Enrichment	MITF	1.97
96	Metaphyseal anadysplasia 2	Enrichment	MMP9	1.97
97	Melanoma, cutaneous malignant 9	Enrichment	TERT	1.97
98	Otosclerosis 12	Enrichment	SMARCA4	1.97
99	Coffin-siris syndrome 4	Enrichment	SMARCA4	1.97
100	Periampullary adenoma	Enrichment	APC	1.97
101	Gastric adenocarcinoma and proximal polyposis of the stomach	Enrichment	APC	1.97
102	14q11.2 microduplication syndrome	Enrichment	CHD8	1.97
103	Idiopathic interstitial pneumonia	Enrichment	TERT	1.97
104	Cholestasis-pigmentary retinopathy-cleft palate syndrome	Enrichment	MED12	1.97
105	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.97
106	Metaphyseal anadysplasia	Enrichment	MMP9	1.97
107	Axenfeld-rieger syndrome	Enrichment	PITX2	1.97
108	Wagner disease	Enrichment	VCAN	1.97
109	Med12-related disorders	Enrichment	MED12	1.97
110	Blepharophimosis - intellectual disability syndrome, mkb type	Enrichment	MED12	1.97
111	Posterior hypospadias	Enrichment	AR	1.97
112	Teratoma	Enrichment	CTNNB1	1.97
113	Primary mediastinal large b-cell lymphoma	Enrichment	XPO1	1.97
114	Palmoplantar keratoderma, epidermolytic, 1	Enrichment	KRT1	1.79
115	Waardenburg syndrome, type 2a	Enrichment	MITF	1.79
116	Intellectual developmental disorder, x-linked, syndromic, lujan-fryns type	Enrichment	MED12	1.79
117	Pierpont syndrome	Enrichment	TBL1XR1	1.79
118	Multicentric osteolysis, nodulosis, and arthropathy	Enrichment	MMP2	1.79
119	Osteoporosis, juvenile	Enrichment	DKK1	1.79
120	Ichthyosis with confetti	Enrichment	KRT1	1.79
121	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.79
122	Ichthyosis, annular epidermolytic, 1	Enrichment	KRT1	1.79
123	Cenani-lenz syndactyly syndrome	Enrichment	APC	1.79
124	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.79
125	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	MYC	1.79
126	Keratosis palmoplantaris striata	Enrichment	KRT1	1.79
127	Interstitial lung disease	Enrichment	TERT	1.79
128	Macrocytic anemia	Enrichment	TERT	1.79
129	Duane retraction syndrome	Enrichment	SALL4	1.79
130	Intellectual developmental disorder, autosomal dominant 41	Enrichment	TBL1XR1	1.79
131	Colon adenocarcinoma	Enrichment	APC	1.79
132	Annular epidermolytic ichthyosis	Enrichment	KRT1	1.79
133	Apc-associated polyposis conditions	Enrichment	APC	1.79
134	Autosomal dominant epidermolytic ichthyosis	Enrichment	KRT1	1.79
135	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CDH1	1.67
136	Robinow syndrome, autosomal dominant 1	Enrichment	DVL3	1.67
137	Chordoma	Enrichment	TBXT	1.67
138	Pitt-hopkins syndrome	Enrichment	TCF4	1.67
139	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	CCND2	1.67
140	Pilomatrixoma	Enrichment	CTNNB1	1.67
141	Alazami syndrome	Enrichment	CTNNB1	1.67
142	Mantle cell lymphoma	Enrichment	CCND1	1.67
143	Intellectual developmental disorder with autism and macrocephaly	Enrichment	CHD8	1.67
144	Lung sarcomatoid carcinoma	Enrichment	TERT	1.67
145	Epidermolytic hyperkeratosis	Enrichment	KRT1	1.67
146	Autosomal dominant robinow syndrome	Enrichment	DVL3	1.67
147	Clear cell papillary renal cell carcinoma	Enrichment	MITF	1.67
148	Hereditary breast carcinoma	Enrichment	APC, CDH1	1.63
149	Epidermolytic hyperkeratosis 1	Enrichment	KRT1	1.57
150	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.57
151	Von hippel-lindau syndrome	Enrichment	CCND1	1.57
152	Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negative	Enrichment	SALL4	1.57
153	Robinow syndrome, autosomal recessive 1	Enrichment	DVL3	1.57
154	Familial adenomatous polyposis 1	Enrichment	APC	1.57
155	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.57
156	Cholangitis, primary sclerosing	Enrichment	TCF4	1.57
157	Robinow syndrome, autosomal dominant 2	Enrichment	DVL3	1.57
158	Fuchs' endothelial dystrophy	Enrichment	TCF4	1.57
159	Congenital ptosis	Enrichment	CHD8	1.57
160	Idiopathic aplastic anemia	Enrichment	TERT	1.57
161	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	MITF, TRRAP	1.50
162	Dyskeratosis congenita, autosomal dominant 1	Enrichment	TERT	1.50
163	Li-fraumeni syndrome	Enrichment	CDKN2A	1.50
164	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.50
165	Wolf-hirschhorn syndrome	Enrichment	CTBP1	1.50
166	Rubinstein-taybi syndrome 1	Enrichment	EP300	1.50
167	Split-hand/foot malformation 1	Enrichment	LEF1	1.50
168	Waardenburg syndrome, type 4a	Enrichment	MITF	1.50
169	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	EP300	1.50
170	Autosomal recessive robinow syndrome	Enrichment	DVL3	1.50
171	Pulmonary fibrosis	Enrichment	TERT	1.50
172	Hoyeraal-hreidarsson syndrome	Enrichment	TERT	1.50
173	Lung squamous cell carcinoma	Enrichment	CDKN2A	1.50
174	Waardenburg syndrome	Enrichment	MITF	1.50
175	Kidney clear cell sarcoma	Enrichment	TERT	1.50
176	Cleft lip with or without cleft palate	Enrichment	CDH1	1.50
177	Waardenburg syndrome, type 1	Enrichment	MITF	1.43
178	Dyskeratosis congenita, autosomal dominant 2	Enrichment	TERT	1.43
179	Gallbladder cancer	Enrichment	CTNNB1	1.43
180	Overgrowth syndrome	Enrichment	CHD8	1.43
181	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	CDKN2A	1.43
182	Spastic paraplegia 4, autosomal dominant	Enrichment	TCF4	1.37
183	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.37
184	Neuroblastoma	Enrichment	SMARCA4	1.37
185	Isolated split hand-split foot malformation	Enrichment	BTRC	1.37
186	Difference of sex development	Enrichment	AR	1.37
187	Tooth agenesis, selective, 1	Enrichment	AXIN2	1.32
188	Charge syndrome	Enrichment	EP300	1.32
189	Mitochondrial myopathy, infantile, transient	Enrichment	MT-CO2	1.32
190	Adult hepatocellular carcinoma	Enrichment	CTNNB1	1.32
191	Ventricular septal defect	Enrichment	SMARCA4	1.32
192	Colonic benign neoplasm	Enrichment	APC	1.32
193	Leukemia, chronic lymphocytic	Enrichment	CCND1	1.28
194	Peters-plus syndrome	Enrichment	PITX2	1.28
195	Aplastic anemia	Enrichment	TERT	1.28
196	Stickler syndrome	Enrichment	VCAN	1.28
197	Familial colorectal cancer	Enrichment	MT-CO2	1.28
198	Mitochondrial myopathy with reversible cytochrome c oxidase deficiency	Enrichment	MT-CO2	1.28
199	Autism	Enrichment	CHD8, TCF7L2	1.24
200	Leukemia, acute lymphoblastic	Enrichment	CDKN2A	1.24
201	Atrial heart septal defect	Enrichment	SMARCA4	1.24
202	46,xy complete gonadal dysgenesis	Enrichment	AR	1.24
203	Interatrial communication	Enrichment	SMARCA4	1.24
204	Epicanthus	Enrichment	TCF4	1.20
205	Meningioma	Enrichment	TERT	1.20
206	Lip and oral cavity carcinoma	Enrichment	CDKN2A	1.20
207	Hypercholesterolemia, familial, 1	Enrichment	SMARCA4	1.17
208	Neural tube defects	Enrichment	TBXT	1.17
209	Acute promyelocytic leukemia	Enrichment	TBL1XR1	1.17
210	Stereotypic movement disorder	Enrichment	TCF4	1.17
211	Cox deficiency, benign infantile mitochondrial myopathy	Enrichment	MT-CO2	1.14
212	Cleft lip/palate	Enrichment	CDH1	1.14
213	Coffin-siris syndrome 1	Enrichment	SMARCA4	1.11
214	Polydactyly, postaxial, type a1	Enrichment	EP300	1.11
215	Corpus callosum, agenesis of	Enrichment	MED12	1.11
216	Anterior segment dysgenesis	Enrichment	PITX2	1.11
217	Familial hypercholesterolemia	Enrichment	SMARCA4	1.11
218	Isolated corpus callosum agenesis	Enrichment	MED12	1.11
219	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	MED12	1.11
220	Hydrocephalus, congenital, 1	Enrichment	MED12	1.08
221	Cleft palate, isolated	Enrichment	SMARCA4	1.06
222	Interstitial lung disease 2	Enrichment	TERT	1.06
223	Cardiomyopathy, dilated, 1e	Enrichment	MED12	1.06
224	Polycystic liver disease	Enrichment	CTNNB1	1.06
225	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	1.06
226	Diffuse large b-cell lymphoma	Enrichment	TBL1XR1	1.01
227	Dyskeratosis congenita	Enrichment	TERT	1.01
228	Endometrial cancer	Enrichment	CDH1	0.97
229	Mitochondrial complex iv deficiency, nuclear type 1	Enrichment	MT-CO2	0.95
230	Tooth agenesis	Enrichment	AXIN2	0.95
231	Autism spectrum disorder	Enrichment	CHD8, TCF4	0.93
232	Ear malformation	Enrichment	MITF	0.92
233	Familial atrial fibrillation	Enrichment	PITX2	0.92
234	Scoliosis	Enrichment	MYF5	0.92
235	Pancreatic cancer	Enrichment	CDKN2A	0.90
236	Tetralogy of fallot	Enrichment	MT-CO2	0.88
237	Mitochondrial complex v deficiency, mitochondrial type 1	Enrichment	MT-CO2	0.88
238	Neuropathy, ataxia, and retinitis pigmentosa	Enrichment	MT-CO2	0.88
239	Striatonigral degeneration, infantile, mitochondrial	Enrichment	MT-CO2	0.88
240	Camptodactyly of fingers	Enrichment	MT-CO2	0.88
241	Hirschsprung disease 1	Enrichment	AXIN2	0.84
242	Differentiated thyroid carcinoma	Enrichment	TERT	0.84
243	Isolated joubert syndrome	Enrichment	CBY1	0.83
244	Nephronophthisis	Enrichment	INCENP	0.79
245	Male infertility	Enrichment	AR	0.78
246	Non-syndromic x-linked intellectual disability	Enrichment	MED12	0.75
247	Non-syndromic genetic deafness	Enrichment	MITF	0.75
248	Leber hereditary optic neuropathy, modifier of	Enrichment	MT-CO2	0.74
249	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	Enrichment	MT-CO2	0.73
250	Cerebral palsy	Enrichment	SMARCA4	0.72
251	Leukemia, acute myeloid	Enrichment	TERT	0.71
252	Type 2 diabetes mellitus	Enrichment	TCF7L2	0.69
253	Nonsyndromic hearing loss	Enrichment	MITF	0.69
254	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	MED12	0.67
255	Joubert syndrome 1	Enrichment	CBY1	0.63
256	Autosomal dominant non-syndromic intellectual disability	Enrichment	TCF4	0.63
257	Hypertelorism	Enrichment	MT-CO2	0.61
258	Spastic ataxia	Enrichment	CACNA1G	0.60
259	Hereditary breast ovarian cancer syndrome	Enrichment	MITF	0.59
260	Myeloma, multiple	Enrichment	CCND1	0.58
261	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	AR	0.58
262	Autosomal recessive non-syndromic intellectual disability	Enrichment	TNIK	0.57
263	Leigh syndrome, nuclear	Enrichment	MT-CO2	0.51
264	Leigh disease	Enrichment	MT-CO2	0.47
265	Rare genetic deafness	Enrichment	MITF	0.46
266	Mitochondrial disease	Enrichment	MT-CO2	0.43
267	Leber plus disease	Enrichment	MT-CO2	0.40
268	Congenital nervous system abnormality	Enrichment	CTNNB1	0.36
269	Nervous system disease	Enrichment	CTNNB1	0.36
270	Complex neurodevelopmental disorder	Enrichment	TCF7L2	0.31
271	Retinitis pigmentosa	Enrichment	MT-CO2	0.16
272	Hereditary retinal dystrophy	Enrichment	VCAN	0.10
273	Fundus dystrophy	Enrichment	VCAN	0.10

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Regulation of nuclear beta catenin signaling and target gene transcription

Pathway Network for Regulation of nuclear beta catenin signaling and target gene transcription

Member Pathways for Regulation of nuclear beta catenin signaling and target gene transcription

Pathways in the Regulation of nuclear beta catenin signaling and target gene transcription SuperPath

Associated Genes for Regulation of nuclear beta catenin signaling and target gene transcription

Associated Disorders for Regulation of nuclear beta catenin signaling and target gene transcription

Disorders associated with Regulation of nuclear beta catenin signaling and target gene transcription SuperPath

STRING Interaction Network for Regulation of nuclear beta catenin signaling and target gene transcription

Sources for Regulation of nuclear beta catenin signaling and target gene transcription