Regulation of nuclear SMAD2/3 signaling

No Pathway Network information available for Regulation of nuclear SMAD2/3 signaling

Pathways in the Regulation of nuclear SMAD2/3 signaling SuperPath

#	Name	Source	Genes
1	Regulation of nuclear SMAD2/3 signaling	PubChem	AKT1 AR ATF2 ATF3 CBFB CDK2 CDKN1A CDKN2B CEBPB CITED1 COL1A2 CREB1 CTBP1 DCP1A DLX1 E2F4 EP300 ESR1 FOS FOXG1 FOXH1 FOXO1 GATA3 GSC HDAC1 HDAC2 HNF4A HSPA8 IFNB1 IL10 IL5 IRF7 ITGB5 JUN KAT2A KAT2B LAMC1 MAX MED15 MEF2C MYC MYOD1 NCOA1 NCOA2 NCOR1 NKX2-5 NR3C1 PIAS3 PIAS4 RBBP4 RBBP7 RBL1 RUNX1 RUNX2 SAP18 SAP30 SERPINE1 SIN3A SIN3B SKI SKIL SMAD2 SMAD3 SMAD4 SMAD7 SNIP1 SP1 TCF3 TFDP1 TFE3 TGIF1 TGIF2 VDR ZBTB17 (see all 74) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RUNX2	RUNX Family Transcription Factor 2	Protein Coding	1
2	DLX1	Distal-Less Homeobox 1	Protein Coding	1
3	TFE3	Transcription Factor Binding To IGHM Enhancer 3	Protein Coding	1
4	MYOD1	Myogenic Differentiation 1	Protein Coding	1
5	SIN3B	SIN3 Transcription Regulator Family Member B	Protein Coding	1
6	TGIF1	TGFB Induced Factor Homeobox 1	Protein Coding	1
7	SKIL	SKI Like Proto-Oncogene	Protein Coding	1
8	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	1
9	GSC	Goosecoid Homeobox	Protein Coding	1
10	DCP1A	Decapping MRNA 1A	Protein Coding	1
11	SNIP1	Smad Nuclear Interacting Protein 1	Protein Coding	1
12	IL10	Interleukin 10	Protein Coding	1
13	IL5	Interleukin 5	Protein Coding	1
14	SAP30	Sin3A Associated Protein 30	Protein Coding	1
15	SAP18	Sin3A Associated Protein 18	Protein Coding	1
16	MEF2C	Myocyte Enhancer Factor 2C	Protein Coding	1
17	TFDP1	Transcription Factor Dp-1	Protein Coding	1
18	KAT2A	Lysine Acetyltransferase 2A	Protein Coding	1
19	ATF3	Activating Transcription Factor 3	Protein Coding	1
20	ZBTB17	Zinc Finger And BTB Domain Containing 17	Protein Coding	1
21	PIAS3	Protein Inhibitor Of Activated STAT 3	Protein Coding	1
22	FOXG1	Forkhead Box G1	Protein Coding	1
23	E2F4	E2F Transcription Factor 4	Protein Coding	1
24	MAX	MYC Associated Transcriptional Regulator X	Protein Coding	1
25	NKX2-5	NK2 Homeobox 5	Protein Coding	1
26	KAT2B	Lysine Acetyltransferase 2B	Protein Coding	1
27	IFNB1	Interferon Beta 1	Protein Coding	1
28	NR3C1	Nuclear Receptor Subfamily 3 Group C Member 1	Protein Coding	1
29	AR	Androgen Receptor	Protein Coding	1
30	RBBP7	RB Binding Protein 7, Chromatin Remodeling Factor	Protein Coding	1
31	RBBP4	RB Binding Protein 4, Chromatin Remodeling Factor	Protein Coding	1
32	CITED1	Cbp/P300 Interacting Transactivator With Glu/Asp Rich Carboxy-Terminal Domain 1	Protein Coding	1
33	GATA3	GATA Binding Protein 3	Protein Coding	1
34	CBFB	Core-Binding Factor Subunit Beta	Protein Coding	1
35	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
36	SKI	SKI Proto-Oncogene	Protein Coding	1
37	CDKN2B	Cyclin Dependent Kinase Inhibitor 2B	Protein Coding	1
38	RBL1	RB Transcriptional Corepressor Like 1	Protein Coding	1
39	COL1A2	Collagen Type I Alpha 2 Chain	Protein Coding	1
40	SMAD7	SMAD Family Member 7	Protein Coding	1
41	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
42	PIAS4	Protein Inhibitor Of Activated STAT 4	Protein Coding	1
43	CDK2	Cyclin Dependent Kinase 2	Protein Coding	1
44	SIN3A	SIN3 Transcription Regulator Family Member A	Protein Coding	1
45	SERPINE1	Serpin Family E Member 1	Protein Coding	1
46	TGIF2	TGFB Induced Factor Homeobox 2	Protein Coding	1
47	SP1	Sp1 Transcription Factor	Protein Coding	1
48	HDAC2	Histone Deacetylase 2	Protein Coding	1
49	CTBP1	C-Terminal Binding Protein 1	Protein Coding	1
50	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
51	MED15	Mediator Complex Subunit 15	Protein Coding	1
52	CEBPB	CCAAT Enhancer Binding Protein Beta	Protein Coding	1
53	NCOA1	Nuclear Receptor Coactivator 1	Protein Coding	1
54	NCOA2	Nuclear Receptor Coactivator 2	Protein Coding	1
55	SMAD4	SMAD Family Member 4	Protein Coding	1
56	FOXH1	Forkhead Box H1	Protein Coding	1
57	SMAD2	SMAD Family Member 2	Protein Coding	1
58	SMAD3	SMAD Family Member 3	Protein Coding	1
59	FOXO1	Forkhead Box O1	Protein Coding	1
60	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
61	TCF3	Transcription Factor 3	Protein Coding	1
62	LAMC1	Laminin Subunit Gamma 1	Protein Coding	1
63	NCOR1	Nuclear Receptor Corepressor 1	Protein Coding	1
64	ATF2	Activating Transcription Factor 2	Protein Coding	1
65	HSPA8	Heat Shock Protein Family A (Hsp70) Member 8	Protein Coding	1
66	RUNX1	RUNX Family Transcription Factor 1	Protein Coding	1
67	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	1
68	ITGB5	Integrin Subunit Beta 5	Protein Coding	1
69	VDR	Vitamin D Receptor	Protein Coding	1
70	IRF7	Interferon Regulatory Factor 7	Protein Coding	1
71	HDAC1	Histone Deacetylase 1	Protein Coding	1
72	HNF4A	Hepatocyte Nuclear Factor 4 Alpha	Protein Coding	1
73	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	1
74	ESR1	Estrogen Receptor 1	Protein Coding	1

Disorders associated with Regulation of nuclear SMAD2/3 signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Witteveen-kolk syndrome	Enrichment	SIN3A, SIN3B	4.53
2	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SKI, SMAD2, SMAD3, SMAD4	4.03
3	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A, CDKN2B	3.22
4	Breast cancer	Enrichment	AKT1, CDKN2B, ESR1, JUN	3.13
5	Loeys-dietz syndrome	Enrichment	SMAD2, SMAD3	2.99
6	Septopreoptic holoprosencephaly	Enrichment	FOXH1, TGIF1	2.53
7	Midline interhemispheric variant of holoprosencephaly	Enrichment	FOXH1, TGIF1	2.53
8	Microform holoprosencephaly	Enrichment	FOXH1, TGIF1	2.47
9	Lobar holoprosencephaly	Enrichment	FOXH1, TGIF1	2.47
10	Alobar holoprosencephaly	Enrichment	FOXH1, TGIF1	2.42
11	Semilobar holoprosencephaly	Enrichment	FOXH1, TGIF1	2.37
12	Ehlers-danlos syndrome	Enrichment	COL1A2, SMAD3	2.33
13	Proteus syndrome	Enrichment	AKT1	2.26
14	Atrial septal defect 7 with or without atrioventricular conduction defects	Enrichment	NKX2-5	2.26
15	Ehlers-danlos syndrome, cardiac valvular type	Enrichment	COL1A2	2.26
16	Prostate cancer, hereditary, x-linked 3	Enrichment	AR	2.26
17	Hypothyroidism, congenital, nongoitrous, 5	Enrichment	NKX2-5	2.26
18	Short stature, auditory canal atresia, mandibular hypoplasia, and skeletal abnormalities	Enrichment	GSC	2.26
19	Androgen insensitivity, partial	Enrichment	AR	2.26
20	Spermatogenic failure, x-linked, 9	Enrichment	RBBP7	2.26
21	Holoprosencephaly 4	Enrichment	TGIF1	2.26
22	Immunodeficiency 39 viral infections	Enrichment	IRF7	2.26
23	Glucocorticoid resistance, generalized	Enrichment	NR3C1	2.26
24	Fanconi renotubular syndrome 4 with maturity-onset diabetes of the young	Enrichment	HNF4A	2.26
25	Shprintzen-goldberg craniosynostosis syndrome	Enrichment	SKI	2.26
26	Agammaglobulinemia 8b, autosomal recessive	Enrichment	TCF3	2.26
27	Combined osteogenesis imperfecta and ehlers-danlos syndrome 2	Enrichment	COL1A2	2.26
28	Renal cell carcinoma, xp11-associated	Enrichment	TFE3	2.26
29	Intellectual developmental disorder, x-linked, syndromic, with pigmentary mosaicism and coarse facies	Enrichment	TFE3	2.26
30	Graft-versus-host disease	Enrichment	IL10	2.26
31	Plasminogen activator inhibitor-1 deficiency	Enrichment	SERPINE1	2.26
32	Immunodeficiency 39	Enrichment	IRF7	2.26
33	Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Enrichment	MEF2C	2.26
34	Agammaglobulinemia 8a, autosomal dominant	Enrichment	TCF3	2.26
35	Ventricular septal defect 3	Enrichment	NKX2-5	2.26
36	Polydactyly-macrocephaly syndrome	Enrichment	MAX	2.26
37	Cowden syndrome 6	Enrichment	AKT1	2.26
38	Congenital myopathy 17	Enrichment	MYOD1	2.26
39	Loeys-dietz syndrome 6	Enrichment	SMAD2	2.26
40	Colorectal cancer 3	Enrichment	SMAD7	2.26
41	Hypoplastic left heart syndrome 2	Enrichment	NKX2-5	2.26
42	Congenital heart defects, multiple types, 8, with or without heterotaxy	Enrichment	SMAD2	2.26
43	Heritable thoracic aortic disease	Enrichment	SMAD4	2.26
44	Rickets	Enrichment	VDR	2.26
45	Chromosome 15q24 deletion syndrome	Enrichment	SIN3A	2.26
46	Hyperinsulinism due to hnf4a deficiency	Enrichment	HNF4A	2.26
47	5q14.3 microdeletion syndrome	Enrichment	MEF2C	2.26
48	Aortic arch interruption	Enrichment	NKX2-5	2.26
49	Complete atrioventricular septal defect without ventricular hypoplasia	Enrichment	MEF2C	2.26
50	Foxg1 syndrome due to intragenic alteration	Enrichment	FOXG1	2.26
51	Complete androgen insensitivity syndrome	Enrichment	AR	2.26
52	Atrial heart septal defect 7	Enrichment	NKX2-5	2.26
53	Foxg1 syndrome due to 14q12 microdeletion	Enrichment	FOXG1	2.26
54	Congenital plasminogen activator inhibitor type 1 deficiency	Enrichment	SERPINE1	2.26
55	Mef2c-related disorder	Enrichment	MEF2C	2.26
56	Burkitt lymphoma	Enrichment	MYC	1.96
57	Hypoparathyroidism, sensorineural deafness, and renal dysplasia syndrome	Enrichment	GATA3	1.96
58	Metaphyseal dysplasia with maxillary hypoplasia with or without brachydactyly	Enrichment	RUNX2	1.96
59	Maturity-onset diabetes of the young, type 1	Enrichment	HNF4A	1.96
60	Myhre syndrome	Enrichment	SMAD4	1.96
61	Storage pool platelet disease	Enrichment	RUNX1	1.96
62	Bruck syndrome 1	Enrichment	COL1A2	1.96
63	Galactosemia ii	Enrichment	NR3C1	1.96
64	Spinal and bulbar muscular atrophy, x-linked 1	Enrichment	AR	1.96
65	Alveolar soft part sarcoma	Enrichment	TFE3	1.96
66	Histiocytoma, angiomatoid fibrous	Enrichment	CREB1	1.96
67	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	1.96
68	Loeys-dietz syndrome 3	Enrichment	SMAD3	1.96
69	Hypotonia, ataxia, developmental delay, and tooth enamel defect syndrome	Enrichment	CTBP1	1.96
70	46,xy sex reversal 1	Enrichment	AR	1.96
71	Androgen insensitivity syndrome	Enrichment	AR	1.96
72	Ehlers-danlos syndrome, arthrochalasia type, 2	Enrichment	COL1A2	1.96
73	Menke-hennekam syndrome 2	Enrichment	EP300	1.96
74	Hypospadias 1, x-linked	Enrichment	AR	1.96
75	Cleidocranial dysplasia 2	Enrichment	CBFB	1.96
76	Neurodevelopmental disorder with hypotonia, craniofacial abnormalities, and seizures	Enrichment	SNIP1	1.96
77	B-lymphoblastic leukemia/lymphoma with hyperdiploidy	Enrichment	GATA3	1.96
78	Hypoparathyroidism-deafness-renal disease syndrome	Enrichment	GATA3	1.96
79	Familial isolated congenital asplenia	Enrichment	NKX2-5	1.96
80	Ehlers-danlos/osteogenesis imperfecta syndrome	Enrichment	COL1A2	1.96
81	B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3)	Enrichment	TCF3	1.96
82	Autosomal dominant nonsyndromic deafness	Enrichment	GATA3	1.96
83	Deletion 5q35	Enrichment	NKX2-5	1.96
84	Posterior hypospadias	Enrichment	AR	1.96
85	Hyperinsulinism	Enrichment	HNF4A	1.96
86	Hyperinsulinism due to hnf1a deficiency	Enrichment	HNF4A	1.96
87	Dentinogenesis imperfecta	Enrichment	COL1A2	1.96
88	B-lymphoblastic leukemia/lymphoma with t(17;19)	Enrichment	TCF3	1.96
89	Tafro syndrome	Enrichment	RUNX1	1.96
90	Colorectal cancer	Enrichment	AKT1, EP300, SMAD4	1.92
91	Cleidocranial dysplasia 1	Enrichment	RUNX2	1.79
92	Juvenile polyposis syndrome	Enrichment	SMAD4	1.79
93	Platelet disorder, familial, with associated myeloid malignancy	Enrichment	RUNX1	1.79
94	Estrogen resistance	Enrichment	ESR1	1.79
95	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	MYC	1.79
96	Loeys-dietz syndrome 1	Enrichment	SMAD2	1.79
97	Cleidocranial dysplasia	Enrichment	RUNX2	1.79
98	Migraine without aura	Enrichment	ESR1	1.79
99	End stage renal disease	Enrichment	GATA3	1.79
100	High bone mass osteogenesis imperfecta	Enrichment	COL1A2	1.79
101	Melanoma of soft tissue	Enrichment	CREB1	1.79
102	Hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with runx1	Enrichment	RUNX1	1.79
103	Renal cell carcinoma	Enrichment	TFE3	1.79
104	Ehlers-danlos syndrome, arthrochalasia type, 1	Enrichment	COL1A2	1.66
105	Maturity-onset diabetes of the young, type 3	Enrichment	HNF4A	1.66
106	Congenital generalized lipodystrophy	Enrichment	FOS	1.66
107	Arthrogryposis multiplex congenita 3, myogenic type	Enrichment	ESR1	1.66
108	Malignant epithelioid hemangioendothelioma	Enrichment	TFE3	1.66
109	Aortic aneurysm	Enrichment	SMAD3	1.66
110	Blood platelet disease	Enrichment	RUNX1	1.66
111	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	CBFB	1.66
112	Hereditary progressive cardiac conduction defect	Enrichment	NKX2-5	1.66
113	Osteogenesis imperfecta with normal sclerae, dominant form	Enrichment	COL1A2	1.66
114	Pseudomyogenic hemangioendothelioma	Enrichment	SERPINE1	1.66
115	Hereditary breast carcinoma	Enrichment	AKT1, ESR1	1.62
116	Vitamin d-dependent rickets, type 2a	Enrichment	VDR	1.57
117	Rhabdomyosarcoma 2	Enrichment	FOXO1	1.57
118	Goldberg-shprintzen syndrome	Enrichment	SKI	1.57
119	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.57
120	Histiocytoid hemangioma	Enrichment	FOS	1.57
121	Aggressive systemic mastocytosis	Enrichment	RUNX1	1.57
122	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	RUNX1	1.57
123	Persistent truncus arteriosus	Enrichment	NKX2-5	1.57
124	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	SMAD4	1.57
125	Thrombocytopenia	Enrichment	RUNX1, SMAD4	1.55
126	Ehlers-danlos syndrome, classic type, 1	Enrichment	COL1A2	1.49
127	Osteogenesis imperfecta, type i	Enrichment	COL1A2	1.49
128	Myopathy, centronuclear, 1	Enrichment	MYOD1	1.49
129	Wolf-hirschhorn syndrome	Enrichment	CTBP1	1.49
130	Conotruncal heart malformations	Enrichment	NKX2-5	1.49
131	Rubinstein-taybi syndrome 1	Enrichment	EP300	1.49
132	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	EP300	1.49
133	Pancytopenia	Enrichment	RUNX1	1.49
134	Double outlet right ventricle	Enrichment	NKX2-5	1.49
135	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10	1.49
136	Breast adenocarcinoma	Enrichment	AKT1	1.49
137	Classic ehlers-danlos syndrome	Enrichment	COL1A2	1.49
138	Inherited cancer-predisposing syndrome	Enrichment	MAX, RUNX1, SMAD4	1.45
139	Osteogenesis imperfecta, type ii	Enrichment	COL1A2	1.43
140	Hypothyroidism, congenital, nongoitrous, 2	Enrichment	NKX2-5	1.43
141	Rett syndrome	Enrichment	FOXG1	1.43
142	Leukemia, chronic myeloid	Enrichment	RUNX1	1.43
143	Renal cell carcinoma with mit translocations	Enrichment	TFE3	1.43
144	Gallbladder cancer	Enrichment	SMAD4	1.43
145	Hereditary hemorrhagic telangiectasia	Enrichment	SMAD4	1.43
146	Rett syndrome, congenital variant	Enrichment	FOXG1	1.37
147	Hypoplastic left heart syndrome	Enrichment	NKX2-5	1.37
148	Difference of sex development	Enrichment	AR	1.37
149	Rheumatoid arthritis	Enrichment	IL10	1.32
150	Charge syndrome	Enrichment	EP300	1.32
151	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	RUNX1	1.32
152	Primary hyperaldosteronism	Enrichment	NR3C1	1.32
153	Cowden syndrome	Enrichment	AKT1	1.32
154	Familial thoracic aortic aneurysm and dissection	Enrichment	SMAD3	1.32
155	Optic nerve disease	Enrichment	FOXG1	1.27
156	Autosomal non-syndromic agammaglobulinemia	Enrichment	TCF3	1.27
157	Primary bone dysplasia	Enrichment	COL1A2	1.27
158	Migraine with or without aura 1	Enrichment	ESR1	1.23
159	Atrial heart septal defect	Enrichment	NKX2-5	1.23
160	46,xy complete gonadal dysgenesis	Enrichment	AR	1.23
161	Osteochondrodysplasia	Enrichment	COL1A2	1.23
162	Interatrial communication	Enrichment	NKX2-5	1.23
163	Meningioma	Enrichment	AKT1	1.20
164	Aortic valve disease 1	Enrichment	NKX2-5	1.16
165	Osteogenesis imperfecta, type iv	Enrichment	COL1A2	1.16
166	Pulmonary disease, chronic obstructive	Enrichment	VDR	1.16
167	Chromosome 1p36 deletion syndrome	Enrichment	SKI	1.16
168	Stereotypic movement disorder	Enrichment	FOXG1	1.16
169	Osteoporosis	Enrichment	COL1A2	1.13
170	Pheochromocytoma	Enrichment	MAX	1.13
171	Aortic aneurysm, familial thoracic 1	Enrichment	SMAD3	1.13
172	Heart disease	Enrichment	NKX2-5	1.13
173	Polydactyly, postaxial, type a1	Enrichment	EP300	1.10
174	Osteogenesis imperfecta, type iii	Enrichment	COL1A2	1.10
175	Rare genetic intellectual disability	Enrichment	EP300	1.10
176	Isolated congenital microcephaly	Enrichment	FOXG1	1.08
177	Melanoma, cutaneous malignant 1	Enrichment	CDKN2B	1.05
178	Polycystic liver disease	Enrichment	HNF4A	1.05
179	Autosomal dominant polycystic liver disease	Enrichment	HNF4A	1.05
180	Human immunodeficiency virus type 1	Enrichment	IL10	1.03
181	Patent foramen ovale	Enrichment	NKX2-5	1.03
182	Behcet syndrome	Enrichment	IL10	1.01
183	Diffuse large b-cell lymphoma	Enrichment	FOXO1	1.01
184	Maturity-onset diabetes of the young	Enrichment	HNF4A	0.98
185	Ovarian cancer	Enrichment	AKT1, AR	0.98
186	Lissencephaly	Enrichment	FOXG1	0.96
187	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	MAX	0.96
188	Hepatocellular carcinoma	Enrichment	VDR	0.95
189	Myocardial infarction	Enrichment	ESR1	0.95
190	Multisystem inflammatory syndrome in children	Enrichment	IFNB1	0.95
191	Brittle bone disorder	Enrichment	COL1A2	0.93
192	Precursor t-cell acute lymphoblastic leukemia	Enrichment	MYC	0.93
193	Familial atrial fibrillation	Enrichment	NKX2-5	0.91
194	Pancreatic cancer	Enrichment	SMAD4	0.89
195	Tetralogy of fallot	Enrichment	NKX2-5	0.88
196	Strabismus	Enrichment	FOXG1	0.86
197	Bladder cancer	Enrichment	CDKN1A	0.83
198	Prostate cancer	Enrichment	AR	0.83
199	Connective tissue disease	Enrichment	SMAD3	0.79
200	Male infertility	Enrichment	AR	0.77
201	Cakut	Enrichment	GATA3	0.77
202	Left ventricular noncompaction	Enrichment	NKX2-5	0.76
203	Fetal akinesia deformation sequence 1	Enrichment	MYOD1	0.74
204	Systemic lupus erythematosus	Enrichment	IL10	0.72
205	Leukemia, acute myeloid	Enrichment	RUNX1	0.71
206	Benign epilepsy with centrotemporal spikes	Enrichment	SNIP1	0.70
207	Type 2 diabetes mellitus	Enrichment	HNF4A	0.69
208	Distal arthrogryposis	Enrichment	MYOD1	0.69
209	Centralopathic epilepsy	Enrichment	SNIP1	0.68
210	Gastric cancer	Enrichment	SMAD4	0.68
211	Nephrotic syndrome	Enrichment	RUNX2	0.68
212	Myeloma, multiple	Enrichment	TCF3	0.58
213	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	AR	0.58
214	Undetermined early-onset epileptic encephalopathy	Enrichment	FOXG1	0.58
215	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	MEF2C	0.56
216	Dilated cardiomyopathy	Enrichment	NKX2-5	0.45
217	Congenital nervous system abnormality	Enrichment	FOXG1	0.36
218	Nervous system disease	Enrichment	FOXG1	0.36
219	Autism spectrum disorder	Enrichment	MEF2C	0.35
220	Microcephaly	Enrichment	EP300	0.31

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Regulation of nuclear SMAD2/3 signaling

Pathway Network for Regulation of nuclear SMAD2/3 signaling

Member Pathways for Regulation of nuclear SMAD2/3 signaling

Pathways in the Regulation of nuclear SMAD2/3 signaling SuperPath

Associated Genes for Regulation of nuclear SMAD2/3 signaling

Associated Disorders for Regulation of nuclear SMAD2/3 signaling

Disorders associated with Regulation of nuclear SMAD2/3 signaling SuperPath

STRING Interaction Network for Regulation of nuclear SMAD2/3 signaling

Sources for Regulation of nuclear SMAD2/3 signaling