Remdesivir Pathway, Pharmacokinetics

Sources:

#	Name	Source	Genes
1	Remdesivir Pathway, Pharmacokinetics	PharmGKB	ADK CES1 CTSA HINT1 NME1 NT5E (see all 6) (see less)
2	Sofosbuvir Pathway, Pharmacokinetics	PharmGKB	CES1 CMPK1 CMPK2 CTSA HINT1 UCK2 (see all 6) (see less)
3	adenine and adenosine salvage VI	PubChem	ADK

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	HINT1	Histidine Triad Nucleotide Binding Protein 1	Protein Coding	2
2	CTSA	Cathepsin A	Protein Coding	2
3	ADK	Adenosine Kinase	Protein Coding	2
4	CES1	Carboxylesterase 1	Protein Coding	2
5	NME1	NME/NM23 Nucleoside Diphosphate Kinase 1	Protein Coding	1
6	NT5E	5''-Nucleotidase Ecto	Protein Coding	1
7	UCK2	Uridine-Cytidine Kinase 2	Protein Coding	1
8	CMPK1	Cytidine/Uridine Monophosphate Kinase 1	Protein Coding	1
9	CMPK2	Cytidine/Uridine Monophosphate Kinase 2	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hypermethioninemia due to adenosine kinase deficiency	Enrichment	ADK	4.13
2	Neuromyotonia and axonal neuropathy, autosomal recessive	Enrichment	HINT1	3.35
3	Calcification of joints and arteries	Enrichment	NT5E	3.35
4	Drug metabolism, altered, ces1-related	Enrichment	CES1	3.35
5	Cathepsin a-related arteriopathy-strokes-leukoencephalopathy	Enrichment	CTSA	3.35
6	Galactosialidosis	Enrichment	CTSA	3.05
7	Combined deficiency of sialidase and beta galactosidase	Enrichment	CTSA	3.05
8	Basal ganglia calcification, idiopathic, 10, autosomal recessive	Enrichment	CMPK2	3.05
9	Basal ganglia calcification, idiopathic, 1	Enrichment	CMPK2	2.45
10	Hydrops fetalis, nonimmune	Enrichment	CTSA	1.94
11	Non-immune hydrops fetalis	Enrichment	CTSA	1.87
12	Peripheral nervous system disease	Enrichment	HINT1	1.85
13	Neuropathy	Enrichment	HINT1	1.85

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Remdesivir Pathway, Pharmacokinetics