Remodeling of Adherens Junctions

No Pathway Network information available for Remodeling of Adherens Junctions

Pathways in the Remodeling of Adherens Junctions SuperPath

#	Name	Source	Genes
1	Remodeling of Adherens Junctions	QIAGEN	ACTA1 ACTA2 ACTB ACTG1 ACTG2 ACTN1 ACTN2 ACTN3 ACTN4 ACTR2 ACTR3 ANAPC1 ANAPC10 ANAPC11 ANAPC13 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ARF6 CAV1 CAV2 CAV3 CBLL1 CDC16 CDC23 CDC27 CDH1 CLIP1 CLTA CLTB CLTC CTNNA1 CTNNA2 CTNNA3 CTNNB1 CTNND1 DNM1 DNM2 EXOC2 FER FYN HGF HGS IQGAP1 MAPRE1 MAPRE2 MAPRE3 MET NME1 PLPP3 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD8 PSMD9 RAB11A RAB11B RAB5A RAB5B RAB5C RAB7A RAB7B RALA SRC TUBA3C TUBA4A TUBA8 TUBB1 TUBB2A TUBB2B TUBB3 TUBB6 TUBB7P TUBD1 TUBE1 TUBG1 TUBG2 UBA1 UBA3 UBA5 UBB UBC UBD UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2F UBE2G1 UBE2H UBE2I UBE2J1 UBE2J2 UBE2L3 UBE2L6 UBE2M UBE2N UBE2Q1 UBE2R2 UBE2S UBE2T UBE2U UBE2V1 UBE2V2 USP17L2 VCL ZYX (see all 126) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACTA1	Actin Alpha 1, Skeletal Muscle	Protein Coding	1
2	ACTA2	Actin Alpha 2, Smooth Muscle	Protein Coding	1
3	ACTB	Actin Beta	Protein Coding	1
4	ACTG1	Actin Gamma 1	Protein Coding	1
5	ACTG2	Actin Gamma 2, Smooth Muscle	Protein Coding	1
6	ACTN1	Actinin Alpha 1	Protein Coding	1
7	ACTN2	Actinin Alpha 2	Protein Coding	1
8	ACTN3	Actinin Alpha 3	Protein Coding	1
9	ACTN4	Actinin Alpha 4	Protein Coding	1
10	ACTR2	Actin Related Protein 2	Protein Coding	1
11	ACTR3	Actin Related Protein 3	Protein Coding	1
12	ANAPC1	Anaphase Promoting Complex Subunit 1	Protein Coding	1
13	ANAPC11	Anaphase Promoting Complex Subunit 11	Protein Coding	1
14	ANAPC2	Anaphase Promoting Complex Subunit 2	Protein Coding	1
15	ANAPC4	Anaphase Promoting Complex Subunit 4	Protein Coding	1
16	ANAPC5	Anaphase Promoting Complex Subunit 5	Protein Coding	1
17	ANAPC7	Anaphase Promoting Complex Subunit 7	Protein Coding	1
18	ANAPC10	Anaphase Promoting Complex Subunit 10	Protein Coding	1
19	ARF6	ARF GTPase 6	Protein Coding	1
20	CAV1	Caveolin 1	Protein Coding	1
21	CAV2	Caveolin 2	Protein Coding	1
22	CAV3	Caveolin 3	Protein Coding	1
23	CBLL1	Cbl Proto-Oncogene Like 1	Protein Coding	1
24	CDC16	Cell Division Cycle 16	Protein Coding	1
25	CDC23	Cell Division Cycle 23	Protein Coding	1
26	CDC27	Cell Division Cycle 27	Protein Coding	1
27	CDH1	Cadherin 1	Protein Coding	1
28	CLTA	Clathrin Light Chain A	Protein Coding	1
29	CLTB	Clathrin Light Chain B	Protein Coding	1
30	CLTC	Clathrin Heavy Chain	Protein Coding	1
31	CTNNA1	Catenin Alpha 1	Protein Coding	1
32	CTNNA2	Catenin Alpha 2	Protein Coding	1
33	CTNNA3	Catenin Alpha 3	Protein Coding	1
34	CTNNB1	Catenin Beta 1	Protein Coding	1
35	CTNND1	Catenin Delta 1	Protein Coding	1
36	ANAPC13	Anaphase Promoting Complex Subunit 13	Protein Coding	1
37	DNM1	Dynamin 1	Protein Coding	1
38	DNM2	Dynamin 2	Protein Coding	1
39	USP17L2	Ubiquitin Specific Peptidase 17 Like Family Member 2	Protein Coding	1
40	UBE2S	Ubiquitin Conjugating Enzyme E2 S	Protein Coding	1
41	FER	FER Tyrosine Kinase	Protein Coding	1
42	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
43	HGF	Hepatocyte Growth Factor	Protein Coding	1
44	HGS	Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate	Protein Coding	1
45	UBE2T	Ubiquitin Conjugating Enzyme E2 T	Protein Coding	1
46	IQGAP1	IQ Motif Containing GTPase Activating Protein 1	Protein Coding	1
47	MAPRE1	Microtubule Associated Protein RP/EB Family Member 1	Protein Coding	1
48	MAPRE2	Microtubule Associated Protein RP/EB Family Member 2	Protein Coding	1
49	MAPRE3	Microtubule Associated Protein RP/EB Family Member 3	Protein Coding	1
50	MET	MET Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	1
51	UBE2U	Ubiquitin Conjugating Enzyme E2 U	Protein Coding	1
52	TUBB6	Tubulin Beta 6 Class V	Protein Coding	1
53	TUBB2B	Tubulin Beta 2B Class IIb	Protein Coding	1
54	RAB7B	RAB7B, Member RAS Oncogene Family	Protein Coding	1
55	UBE2F	Ubiquitin Conjugating Enzyme E2 F (Putative)	Protein Coding	1
56	NME1	NME/NM23 Nucleoside Diphosphate Kinase 1	Protein Coding	1
57	PSMD6	Proteasome 26S Subunit, Non-ATPase 6	Protein Coding	1
58	PLPP3	Phospholipid Phosphatase 3	Protein Coding	1
59	PSMC1	Proteasome 26S Subunit, ATPase 1	Protein Coding	1
60	PSMC2	Proteasome 26S Subunit, ATPase 2	Protein Coding	1
61	PSMC3	Proteasome 26S Subunit, ATPase 3	Protein Coding	1
62	PSMC4	Proteasome 26S Subunit, ATPase 4	Protein Coding	1
63	PSMC5	Proteasome 26S Subunit, ATPase 5	Protein Coding	1
64	PSMC6	Proteasome 26S Subunit, ATPase 6	Protein Coding	1
65	PSMD1	Proteasome 26S Subunit, Non-ATPase 1	Protein Coding	1
66	PSMD10	Proteasome 26S Subunit, Non-ATPase 10	Protein Coding	1
67	PSMD11	Proteasome 26S Subunit, Non-ATPase 11	Protein Coding	1
68	PSMD12	Proteasome 26S Subunit, Non-ATPase 12	Protein Coding	1
69	PSMD13	Proteasome 26S Subunit, Non-ATPase 13	Protein Coding	1
70	PSMD14	Proteasome 26S Subunit, Non-ATPase 14	Protein Coding	1
71	PSMD2	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 2	Protein Coding	1
72	PSMD3	Proteasome 26S Subunit, Non-ATPase 3	Protein Coding	1
73	PSMD4	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 4	Protein Coding	1
74	PSMD5	Proteasome 26S Subunit, Non-ATPase 5	Protein Coding	1
75	PSMD8	Proteasome 26S Subunit, Non-ATPase 8	Protein Coding	1
76	PSMD9	Proteasome 26S Subunit, Non-ATPase 9	Protein Coding	1
77	RAB11A	RAB11A, Member RAS Oncogene Family	Protein Coding	1
78	RAB11B	RAB11B, Member RAS Oncogene Family	Protein Coding	1
79	RAB5A	RAB5A, Member RAS Oncogene Family	Protein Coding	1
80	RAB5B	RAB5B, Member RAS Oncogene Family	Protein Coding	1
81	RAB5C	RAB5C, Member RAS Oncogene Family	Protein Coding	1
82	RAB7A	RAB7A, Member RAS Oncogene Family	Protein Coding	1
83	RALA	RAS Like Proto-Oncogene A	Protein Coding	1
84	CLIP1	CAP-Gly Domain Containing Linker Protein 1	Protein Coding	1
85	EXOC2	Exocyst Complex Component 2	Protein Coding	1
86	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
87	TUBA4A	Tubulin Alpha 4a	Protein Coding	1
88	TUBA3C	Tubulin Alpha 3c	Protein Coding	1
89	TUBA8	Tubulin Alpha 8	Protein Coding	1
90	TUBB1	Tubulin Beta 1 Class VI	Protein Coding	1
91	TUBB2A	Tubulin Beta 2A Class IIa	Protein Coding	1
92	TUBB3	Tubulin Beta 3 Class III	Protein Coding	1
93	TUBB7P	Tubulin Beta 7 Pseudogene	Pseudogene	1
94	TUBD1	Tubulin Delta 1	Protein Coding	1
95	TUBE1	Tubulin Epsilon 1	Protein Coding	1
96	TUBG1	Tubulin Gamma 1	Protein Coding	1
97	TUBG2	Tubulin Gamma 2	Protein Coding	1
98	UBB	Ubiquitin B	Protein Coding	1
99	UBC	Ubiquitin C	Protein Coding	1
100	UBD	Ubiquitin Like Modifier D	Protein Coding	1
101	UBA1	Ubiquitin Like Modifier Activating Enzyme 1	Protein Coding	1
102	UBA3	Ubiquitin Like Modifier Activating Enzyme 3	Protein Coding	1
103	UBA5	Ubiquitin Like Modifier Activating Enzyme 5	Protein Coding	1
104	UBE2A	Ubiquitin Conjugating Enzyme E2 A	Protein Coding	1
105	UBE2B	Ubiquitin Conjugating Enzyme E2 B	Protein Coding	1
106	UBE2C	Ubiquitin Conjugating Enzyme E2 C	Protein Coding	1
107	UBE2D1	Ubiquitin Conjugating Enzyme E2 D1	Protein Coding	1
108	UBE2D2	Ubiquitin Conjugating Enzyme E2 D2	Protein Coding	1
109	UBE2D3	Ubiquitin Conjugating Enzyme E2 D3	Protein Coding	1
110	UBE2E1	Ubiquitin Conjugating Enzyme E2 E1	Protein Coding	1
111	UBE2E3	Ubiquitin Conjugating Enzyme E2 E3	Protein Coding	1
112	UBE2G1	Ubiquitin Conjugating Enzyme E2 G1	Protein Coding	1
113	UBE2H	Ubiquitin Conjugating Enzyme E2 H	Protein Coding	1
114	UBE2I	Ubiquitin Conjugating Enzyme E2 I	Protein Coding	1
115	UBE2J1	Ubiquitin Conjugating Enzyme E2 J1	Protein Coding	1
116	UBE2J2	Ubiquitin Conjugating Enzyme E2 J2	Protein Coding	1
117	UBE2L3	Ubiquitin Conjugating Enzyme E2 L3	Protein Coding	1
118	UBE2L6	Ubiquitin Conjugating Enzyme E2 L6	Protein Coding	1
119	UBE2M	Ubiquitin Conjugating Enzyme E2 M	Protein Coding	1
120	UBE2N	Ubiquitin Conjugating Enzyme E2 N	Protein Coding	1
121	UBE2Q1	Ubiquitin Conjugating Enzyme E2 Q1	Protein Coding	1
122	UBE2R2	Ubiquitin Conjugating Enzyme E2 R2	Protein Coding	1
123	UBE2V1	Ubiquitin Conjugating Enzyme E2 V1	Protein Coding	1
124	UBE2V2	Ubiquitin Conjugating Enzyme E2 V2	Protein Coding	1
125	VCL	Vinculin	Protein Coding	1
126	ZYX	Zyxin	Protein Coding	1

Disorders associated with Remodeling of Adherens Junctions SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Lissencephaly	Enrichment	ACTG1, TUBB2B, TUBB3, TUBG1	4.43
2	Blepharocheilodontic syndrome 1	Enrichment	CDH1, CTNND1	4.07
3	Childhood hepatocellular carcinoma	Enrichment	CTNNB1, MET	4.07
4	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	4.07
5	Autosomal dominant macrothrombocytopenia	Enrichment	ACTN1, TUBA8, TUBB1	4.05
6	Tubulinopathy-associated dysgyria	Enrichment	TUBB2B, TUBB3	3.59
7	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CDH1, CTNNA1	3.29
8	Tubulinopathy	Enrichment	TUBB2A, TUBB2B	3.29
9	Congenital fibrosis of the extraocular muscles	Enrichment	TUBB2B, TUBB3	2.90
10	Cleft lip with or without cleft palate	Enrichment	CDH1, CTNND1	2.90
11	Colorectal cancer	Enrichment	CDH1, CTNNA1, CTNNB1, MET, SRC	2.89
12	Baraitser-winter syndrome 1	Enrichment	ACTB	2.03
13	Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement	Enrichment	TUBB3	2.03
14	Focal segmental glomerulosclerosis 1	Enrichment	ACTN4	2.03
15	Lipodystrophy, congenital generalized, type 3	Enrichment	CAV1	2.03
16	Macular dystrophy, patterned, 2	Enrichment	CTNNA1	2.03
17	Deafness, autosomal recessive 39	Enrichment	HGF	2.03
18	Cardiomyopathy, dilated, 1aa, with or without left ventricular noncompaction	Enrichment	ACTN2	2.03
19	Congenital myopathy 2a, typical, autosomal dominant	Enrichment	ACTA1	2.03
20	Fanconi anemia, complementation group t	Enrichment	UBE2T	2.03
21	Charcot-marie-tooth disease, dominant intermediate b	Enrichment	DNM2	2.03
22	Macrothrombocytopenia, isolated, 1, autosomal dominant	Enrichment	TUBB1	2.03
23	Myopathy, scapulohumeroperoneal	Enrichment	ACTA1	2.03
24	Pulmonary hypertension, primary, 3	Enrichment	CAV1	2.03
25	Arrhythmogenic right ventricular dysplasia, familial, 13	Enrichment	CTNNA3	2.03
26	Hiatt-neu-cooper neurodevelopmental syndrome	Enrichment	RALA	2.03
27	Megacystis-microcolon-intestinal hypoperistalsis syndrome 5	Enrichment	ACTG2	2.03
28	Charcot-marie-tooth disease, axonal, type 2b	Enrichment	RAB7A	2.03
29	Cortical dysplasia, complex, with other brain malformations 9	Enrichment	CTNNA2	2.03
30	Congenital myopathy 8	Enrichment	ACTN2	2.03
31	Intellectual developmental disorder, x-linked, syndromic, nascimento type	Enrichment	UBE2A	2.03
32	Stankiewicz-isidor syndrome	Enrichment	PSMD12	2.03
33	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	2.03
34	Charcot-marie-tooth disease type 2b	Enrichment	RAB7A	2.03
35	Osteofibrous dysplasia	Enrichment	MET	2.03
36	Syndromic x-linked intellectual disability nascimento type	Enrichment	UBE2A	2.03
37	Ferguson-bonni neurodevelopmental syndrome	Enrichment	ANAPC7	2.03
38	Lipodystrophy, familial partial, type 7	Enrichment	CAV1	2.03
39	Deafness, cataract, impaired intellectual development, and polyneuropathy	Enrichment	PSMC3	2.03
40	Deafness, autosomal recessive 97	Enrichment	MET	2.03
41	Skin creases, congenital symmetric circumferential, 2	Enrichment	MAPRE2	2.03
42	Cardiomyopathy, dilated, 1w	Enrichment	VCL	2.03
43	Actn3 deficiency	Enrichment	ACTN3	2.03
44	Neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter	Enrichment	RAB11B	2.03
45	Becker nevus syndrome	Enrichment	ACTB	2.03
46	Dystonia-deafness syndrome 1	Enrichment	ACTB	2.03
47	Rothmund-thomson syndrome, type 1	Enrichment	ANAPC1	2.03
48	Autism 9	Enrichment	MET	2.03
49	Visceral neuropathy, familial, 3, autosomal dominant	Enrichment	ACTG2	2.03
50	Cortical dysplasia, complex, with other brain malformations 7	Enrichment	TUBB2B	2.03
51	Lethal congenital contracture syndrome 5	Enrichment	DNM2	2.03
52	Cardiomyopathy, familial hypertrophic, 15	Enrichment	VCL	2.03
53	Congenital myopathy 2b, severe infantile, autosomal recessive	Enrichment	ACTA1	2.03
54	Bleeding disorder, platelet-type, 15	Enrichment	ACTN1	2.03
55	Oocyte/zygote/embryo maturation arrest 23	Enrichment	TUBA4A	2.03
56	Frontotemporal dementia and/or amyotrophic lateral sclerosis 9	Enrichment	TUBA4A	2.03
57	Autosomal dominant familial visceral neuropathy	Enrichment	ACTG2	2.03
58	Thrombocytopenia 6	Enrichment	SRC	2.03
59	Facial palsy, congenital, with ptosis and velopharyngeal dysfunction	Enrichment	TUBB6	2.03
60	Congenital myopathy 2c, severe infantile, autosomal dominant	Enrichment	ACTA1	2.03
61	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	2.03
62	Myopathy, distal, 6, adult-onset, autosomal dominant	Enrichment	ACTN2	2.03
63	Macrothrombocytopenia, isolated, 2, autosomal dominant	Enrichment	TUBA8	2.03
64	Adenoid ameloblastoma	Enrichment	CTNNB1	2.03
65	Arthrogryposis, distal, type 11	Enrichment	MET	2.03
66	Baraitser-winter syndrome	Enrichment	ACTB	2.03
67	Congenital myopathy 26	Enrichment	TUBA4A	2.03
68	Spastic ataxia 11, autosomal dominant	Enrichment	TUBA4A	2.03
69	Amyotrophic lateral sclerosis type 22	Enrichment	TUBA4A	2.03
70	Autosomal dominant charcot-marie-tooth disease type 2m	Enrichment	DNM2	2.03
71	Breast lobular carcinoma	Enrichment	CDH1	2.03
72	Polymicrogyria with optic nerve hypoplasia	Enrichment	TUBA8	2.03
73	Zebra body myopathy	Enrichment	ACTA1	2.03
74	Congenital smooth muscle hamartoma	Enrichment	ACTB	2.03
75	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	2.03
76	Actin-accumulation myopathy	Enrichment	ACTA1	2.03
77	Myopathic intestinal pseudoobstruction	Enrichment	ACTG2	2.03
78	Microcystic stromal tumor	Enrichment	CTNNB1	2.03
79	Actg2 visceral myopathy	Enrichment	ACTG2	2.03
80	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	ACTN2, CTNNA3	2.03
81	Thrombocytopenia	Enrichment	ACTN1, SRC, TUBB1	2.00
82	Undetermined early-onset epileptic encephalopathy	Enrichment	CLTC, DNM1, UBA5	1.82
83	Centronuclear myopathy	Enrichment	ACTA1, DNM2	1.80
84	Hepatocellular carcinoma	Enrichment	CTNNB1, MET	1.76
85	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.73
86	Vexas syndrome	Enrichment	UBA1	1.73
87	Aortic aneurysm, familial thoracic 2	Enrichment	ACTA2	1.73
88	Deafness, autosomal dominant 20	Enrichment	ACTG1	1.73
89	Smooth muscle dysfunction syndrome	Enrichment	ACTA2	1.73
90	Aortic aneurysm, familial thoracic 6	Enrichment	ACTA2	1.73
91	Baraitser-winter syndrome 2	Enrichment	ACTG1	1.73
92	Moyamoya disease 5	Enrichment	ACTA2	1.73
93	Spinocerebellar ataxia, autosomal recessive 24	Enrichment	UBA5	1.73
94	Cortical dysplasia, complex, with other brain malformations 4	Enrichment	TUBG1	1.73
95	Blepharocheilodontic syndrome 2	Enrichment	CTNND1	1.73
96	Birk-aharoni syndrome	Enrichment	PSMC1	1.73
97	Spinal muscular atrophy, x-linked 2	Enrichment	UBA1	1.73
98	Papillary renal cell carcinoma	Enrichment	MET	1.73
99	Cortical dysplasia, complex, with other brain malformations 1	Enrichment	TUBB3	1.73
100	17q24.2 microdeletion syndrome	Enrichment	PSMD12	1.73
101	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.73
102	Multiple benign circumferential skin creases on limbs	Enrichment	MAPRE2	1.73
103	Neurodevelopmental disorder with dysmorphic facies and cerebellar hypoplasia	Enrichment	EXOC2	1.73
104	Qualitative or quantitative defects of caveolin-3	Enrichment	CAV3	1.73
105	Teratoma	Enrichment	CTNNB1	1.73
106	Intestinal obstruction	Enrichment	ACTG2	1.73
107	Submucosal cleft palate	Enrichment	UBB	1.73
108	Cleft hard palate	Enrichment	UBB	1.73
109	Desmoid disease, hereditary	Enrichment	CTNNB1	1.56
110	Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss	Enrichment	TUBB1	1.56
111	Uvula, bifid	Enrichment	UBB	1.56
112	Myopathy, centronuclear, x-linked	Enrichment	DNM2	1.56
113	Rippling muscle disease 2	Enrichment	CAV3	1.56
114	Cleft soft palate	Enrichment	UBB	1.56
115	Long qt syndrome 9	Enrichment	CAV3	1.56
116	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.56
117	Myopathy, distal, tateyama type	Enrichment	CAV3	1.56
118	Anus, imperforate	Enrichment	CTNNB1	1.56
119	Cortical dysplasia, complex, with other brain malformations 5	Enrichment	TUBB2A	1.56
120	Developmental and epileptic encephalopathy 44	Enrichment	UBA5	1.56
121	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.56
122	Intellectual developmental disorder, autosomal dominant 56	Enrichment	CLTC	1.56
123	Developmental and epileptic encephalopathy 31b	Enrichment	DNM1	1.56
124	Desmoid tumor	Enrichment	CTNNB1	1.56
125	Intrinsic cardiomyopathy	Enrichment	ACTN2	1.56
126	Butterfly-shaped pigment dystrophy	Enrichment	CTNNA1	1.56
127	Renal cell carcinoma	Enrichment	MET	1.56
128	Thyroid hemiagenesis	Enrichment	PSMD3	1.56
129	Microcephaly	Enrichment	ACTB, ACTG1, CTNNB1, PSMC3	1.56
130	Bladder cancer	Enrichment	CTNNA3, CTNNB1	1.53
131	Long qt syndrome	Enrichment	CAV3, CTNNA3	1.48
132	Lung cancer	Enrichment	ACTA2, MET	1.45
133	Nemaline myopathy 2	Enrichment	ACTA1	1.44
134	Megacystis-microcolon-intestinal hypoperistalsis syndrome 1	Enrichment	ACTG2	1.44
135	Polyposis syndrome, hereditary mixed, 1	Enrichment	CTNNA1	1.44
136	Autoimmune lymphoproliferative syndrome	Enrichment	ACTA2	1.44
137	Pilomatrixoma	Enrichment	CTNNB1	1.44
138	Aminoacylase 1 deficiency	Enrichment	ACTB	1.44
139	Alazami syndrome	Enrichment	CTNNB1	1.44
140	Neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 1	Enrichment	CLTC	1.44
141	Craniopharyngioma	Enrichment	CTNNB1	1.44
142	Intermediate nemaline myopathy	Enrichment	ACTA1	1.44
143	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.44
144	Familial hypertrophic cardiomyopathy	Enrichment	ACTN2, CAV3	1.43
145	Dilated cardiomyopathy	Enrichment	ACTA1, ACTN2, VCL	1.42
146	Visceral myopathy 1	Enrichment	ACTG2	1.34
147	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.34
148	Congenital myopathy 3 with rigid spine	Enrichment	ACTA1	1.34
149	Chromosome 15q11.2 deletion syndrome	Enrichment	TUBG1	1.34
150	Developmental and epileptic encephalopathy 31a	Enrichment	DNM1	1.34
151	Coloboma of choroid and retina	Enrichment	ACTG1	1.34
152	Diffuse cutaneous systemic sclerosis	Enrichment	CAV1	1.34
153	Severe congenital nemaline myopathy	Enrichment	ACTA1	1.34
154	Myopathy	Enrichment	ACTA1, DNM2	1.27
155	Developmental dysplasia of the hip 1	Enrichment	PSMC3	1.26
156	Myopathy, centronuclear, 1	Enrichment	DNM2	1.26
157	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.26
158	Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 1	Enrichment	TUBB2B	1.26
159	Moyamoya disease 1	Enrichment	ACTA2	1.26
160	Inflammatory myofibroblastic tumor	Enrichment	CLTC	1.26
161	Intestinal pseudo-obstruction	Enrichment	ACTG2	1.26
162	Patent ductus arteriosus	Enrichment	PSMC3	1.26
163	Adrenocortical carcinoma	Enrichment	CTNNB1	1.26
164	Limited scleroderma	Enrichment	CAV1	1.26
165	Typical nemaline myopathy	Enrichment	ACTA1	1.26
166	Myelofibrosis	Enrichment	SRC	1.20
167	Polymicrogyria, bilateral perisylvian, x-linked	Enrichment	TUBB2B	1.20
168	Renal cell carcinoma, papillary, 1	Enrichment	MET	1.20
169	Noonan syndrome 3	Enrichment	CLTC	1.20
170	Renal cell carcinoma with mit translocations	Enrichment	CLTC	1.20
171	Gallbladder cancer	Enrichment	CTNNB1	1.20
172	Childhood-onset nemaline myopathy	Enrichment	ACTA1	1.20
173	Ovarian cancer	Enrichment	CDH1, CTNNB1, MET	1.17
174	Arthrogryposis, distal, type 1a	Enrichment	MET	1.14
175	Myopathy, tubular aggregate, 1	Enrichment	CAV3	1.14
176	Lennox-gastaut syndrome	Enrichment	DNM1	1.14
177	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.14
178	Autosomal dominant non-syndromic intellectual disability	Enrichment	CLTC, RAB11A	1.10
179	Adult hepatocellular carcinoma	Enrichment	CTNNB1	1.09
180	Bilateral perisylvian polymicrogyria	Enrichment	TUBB2B	1.09
181	Familial isolated dilated cardiomyopathy	Enrichment	ACTN2, VCL	1.06
182	Cat eye syndrome	Enrichment	ACTG1	1.05
183	Polymicrogyria	Enrichment	PSMC3	1.05
184	Nemaline myopathy	Enrichment	ACTA1	1.05
185	Hereditary breast ovarian cancer syndrome	Enrichment	CTNNA1, CTNNA2	1.03
186	Heritable pulmonary arterial hypertension	Enrichment	CAV1	1.01
187	Congenital hypothyroidism	Enrichment	TUBB1	0.97
188	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	CTNNA3	0.97
189	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	CTNNA3	0.97
190	Stereotypic movement disorder	Enrichment	DNM1	0.94
191	Osteoporosis	Enrichment	SRC	0.91
192	Medulloblastoma	Enrichment	CTNNB1	0.91
193	Lung cancer susceptibility 3	Enrichment	ACTA2	0.91
194	Cleft lip/palate	Enrichment	CDH1	0.91
195	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	CTNNA3	0.91
196	Inherited cancer-predisposing syndrome	Enrichment	CDH1, CTNNA1, MET	0.90
197	Renal cell carcinoma, nonpapillary	Enrichment	MET	0.88
198	Congenital myopathy 4a, autosomal dominant	Enrichment	ACTA1	0.88
199	Creatine phosphokinase, elevated serum	Enrichment	CAV3	0.86
200	Isolated elevated serum creatine phosphokinase levels	Enrichment	CAV3	0.86
201	Isolated congenital microcephaly	Enrichment	RAB11A	0.86
202	Sudden infant death syndrome	Enrichment	CAV3	0.83
203	Polycystic liver disease	Enrichment	CTNNB1	0.83
204	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	0.83
205	Neuromuscular disease	Enrichment	ACTA1	0.81
206	Patent foramen ovale	Enrichment	PSMC3	0.81
207	Congenital myopathy	Enrichment	ACTA1	0.79
208	Craniosynostosis	Enrichment	CTNNA1	0.77
209	Endometrial cancer	Enrichment	CDH1	0.75
210	Hepatoblastoma	Enrichment	CTNNB1	0.75
211	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	HGF, MET	0.70
212	Cardiomyopathy, familial hypertrophic, 1	Enrichment	CAV3	0.70
213	Hydrops fetalis, nonimmune	Enrichment	ACTA1	0.67
214	Prostate cancer	Enrichment	CDH1	0.62
215	Long qt syndrome 1	Enrichment	CAV3	0.61
216	Non-immune hydrops fetalis	Enrichment	ACTA1	0.60
217	Connective tissue disease	Enrichment	ACTA2	0.59
218	Cakut	Enrichment	ACTG1	0.57
219	Genetic steroid-resistant nephrotic syndrome	Enrichment	ACTN4	0.57
220	Fanconi anemia, complementation group a	Enrichment	UBE2T	0.55
221	Left ventricular noncompaction	Enrichment	ACTN2	0.55
222	Developmental and epileptic encephalopathy	Enrichment	UBA5	0.54
223	Non-syndromic genetic deafness	Enrichment	ACTG1	0.54
224	Fetal akinesia deformation sequence 1	Enrichment	ACTA1	0.53
225	Systemic lupus erythematosus	Enrichment	UBE2L3	0.52
226	Charcot-marie-tooth disease	Enrichment	DNM2	0.50
227	Complex neurodevelopmental disorder	Enrichment	PSMD12, RALA	0.49
228	Distal arthrogryposis	Enrichment	ACTA1	0.49
229	Nonsyndromic hearing loss	Enrichment	ACTG1	0.49
230	Gastric cancer	Enrichment	CDH1	0.48
231	Hypertrophic cardiomyopathy	Enrichment	ACTN2	0.48
232	Optic atrophy plus syndrome	Enrichment	TUBB6	0.47
233	West syndrome	Enrichment	DNM1	0.47
234	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	ACTA2	0.47
235	Hereditary breast carcinoma	Enrichment	CDH1	0.47
236	Sensorineural hearing loss	Enrichment	HGF	0.44
237	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ACTG1	0.41
238	Spastic ataxia	Enrichment	TUBB3	0.41
239	Autosomal recessive non-syndromic intellectual disability	Enrichment	CLIP1	0.38
240	Breast cancer	Enrichment	CDH1	0.30
241	Rare genetic deafness	Enrichment	ACTG1	0.28
242	Congenital nervous system abnormality	Enrichment	CTNNB1	0.20
243	Nervous system disease	Enrichment	CTNNB1	0.20
244	Hereditary retinal dystrophy	Enrichment	CTNNA1	0.03
245	Fundus dystrophy	Enrichment	CTNNA1	0.03

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Remodeling of Adherens Junctions

Pathway Network for Remodeling of Adherens Junctions

Member Pathways for Remodeling of Adherens Junctions

Pathways in the Remodeling of Adherens Junctions SuperPath

Associated Genes for Remodeling of Adherens Junctions

Associated Disorders for Remodeling of Adherens Junctions

Disorders associated with Remodeling of Adherens Junctions SuperPath

STRING Interaction Network for Remodeling of Adherens Junctions

Sources for Remodeling of Adherens Junctions