Respiratory Syncytial Virus Infection Pathway

Pathway network for the Respiratory Syncytial Virus Infection Pathway SuperPath

Sources:

Reactome

Pathways in the Respiratory Syncytial Virus Infection Pathway SuperPath

#	Name	Source	Genes
1	Respiratory Syncytial Virus Infection Pathway	Reactome	AGRN ARIH1 BCAP31 BECN1 CCNC CD14 CD209 CDK19 CDK8 CLEC4M CREBBP CSNK2A1 CSNK2A2 CSNK2B CUL5 CX3CR1 EGFR EIF2AK2 ELOB ELOC EP300 FURIN GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 H2BC15 HERC5 HSP90AA1 HSP90AB1 HSPA8 HSPG2 IFIH1 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR1 IFNAR2 IFNB1 IGF1R IRF3 ISG15 JAK1 KPNB1 LY96 MAP1B MAVS MED1 MED10 MED11 MED12 MED13 MED13L MED14 MED15 MED16 MED17 MED18 MED19 MED20 MED21 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 MED9 NCL OAS2 PPP1CA PPP1CB PPP1CC RAB5A RAB5B RAB5C RBX1 RIGI RPS27A SDC1 SDC2 SDC3 SDC4 SEC11A SEC11C SPCS1 SPCS2 SPCS3 STAT2 TLR2 TLR3 TLR4 TLR6 TLR7 TRIM25 TYK2 UBA52 UBB UBC UBE2L6 XPO1 (see all 121) (see less)
2	RSV-host interactions	Reactome	AGRN ARIH1 BCAP31 BECN1 CCNC CD14 CD209 CDK19 CDK8 CLEC4M CREBBP CUL5 CX3CR1 EIF2AK2 ELOB ELOC EP300 GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 H2BC15 HERC5 HSPG2 IFIH1 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR1 IFNAR2 IFNB1 IRF3 ISG15 JAK1 LY96 MAP1B MAVS MED1 MED10 MED11 MED12 MED13 MED13L MED14 MED15 MED16 MED17 MED18 MED19 MED20 MED21 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 MED9 OAS2 RBX1 RIGI RPS27A SDC1 SDC2 SDC3 SDC4 STAT2 TLR2 TLR3 TLR4 TLR6 TLR7 TRIM25 TYK2 UBA52 UBB UBC UBE2L6 (see all 98) (see less)
3	Respiratory syncytial virus (RSV) genome replication, transcription and translation	Reactome	CSNK2A1 CSNK2A2 CSNK2B FURIN HSP90AA1 HSP90AB1 HSPA8 KPNB1 PPP1CA PPP1CB PPP1CC SEC11A SEC11C SPCS1 SPCS2 SPCS3 XPO1 (see all 17) (see less)
4	Maturation of hRSV A proteins	Reactome	CSNK2A1 CSNK2A2 CSNK2B FURIN KPNB1 PPP1CA PPP1CB PPP1CC SEC11A SEC11C SPCS1 SPCS2 SPCS3 XPO1 (see all 14) (see less)

Gene overlap in member pathways for Respiratory Syncytial Virus Infection Pathway SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CSNK2A1	Casein Kinase 2 Alpha 1	Protein Coding	3
2	CSNK2A2	Casein Kinase 2 Alpha 2	Protein Coding	3
3	CSNK2B	Casein Kinase 2 Beta	Protein Coding	3
4	SEC11A	SEC11 Homolog A, Signal Peptidase Complex Subunit	Protein Coding	3
5	SPCS1	Signal Peptidase Complex Subunit 1	Protein Coding	3
6	KPNB1	Karyopherin Subunit Beta 1	Protein Coding	3
7	FURIN	Furin, Paired Basic Amino Acid Cleaving Enzyme	Protein Coding	3
8	PPP1CA	Protein Phosphatase 1 Catalytic Subunit Alpha	Protein Coding	3
9	PPP1CB	Protein Phosphatase 1 Catalytic Subunit Beta	Protein Coding	3
10	PPP1CC	Protein Phosphatase 1 Catalytic Subunit Gamma	Protein Coding	3
11	SPCS3	Signal Peptidase Complex Subunit 3	Protein Coding	3
12	XPO1	Exportin 1	Protein Coding	3
13	SEC11C	SEC11 Homolog C, Signal Peptidase Complex Subunit	Protein Coding	3
14	SPCS2	Signal Peptidase Complex Subunit 2	Protein Coding	3
15	MED6	Mediator Complex Subunit 6	Protein Coding	2
16	MED16	Mediator Complex Subunit 16	Protein Coding	2
17	GPC6	Glypican 6	Protein Coding	2
18	BCAP31	B Cell Receptor Associated Protein 31	Protein Coding	2
19	CDK8	Cyclin Dependent Kinase 8	Protein Coding	2
20	CLEC4M	C-Type Lectin Domain Family 4 Member M	Protein Coding	2
21	TLR6	Toll Like Receptor 6	Protein Coding	2
22	MED8	Mediator Complex Subunit 8	Protein Coding	2
23	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	2
24	CX3CR1	C-X3-C Motif Chemokine Receptor 1	Protein Coding	2
25	EP300	EP300 Lysine Acetyltransferase	Protein Coding	2
26	MED19	Mediator Complex Subunit 19	Protein Coding	2
27	GPC2	Glypican 2	Protein Coding	2
28	GPC4	Glypican 4	Protein Coding	2
29	GPC5	Glypican 5	Protein Coding	2
30	CDK19	Cyclin Dependent Kinase 19	Protein Coding	2
31	MED13L	Mediator Complex Subunit 13L	Protein Coding	2
32	RIGI	RNA Sensor RIG-I	Protein Coding	2
33	LY96	Lymphocyte Antigen 96	Protein Coding	2
34	ARIH1	Ariadne RBR E3 Ubiquitin Protein Ligase 1	Protein Coding	2
35	GPC3	Glypican 3	Protein Coding	2
36	GPC1	Glypican 1	Protein Coding	2
37	MED4	Mediator Complex Subunit 4	Protein Coding	2
38	CD209	CD209 Molecule	Protein Coding	2
39	HSPA8	Heat Shock Protein Family A (Hsp70) Member 8	Protein Coding	2
40	HSP90AA1	Heat Shock Protein 90 Alpha Family Class A Member 1	Protein Coding	2
41	HSP90AB1	Heat Shock Protein 90 Alpha Family Class B Member 1	Protein Coding	2
42	HSPG2	Heparan Sulfate Proteoglycan 2	Protein Coding	2
43	IFNA1	Interferon Alpha 1	Protein Coding	2
44	IFNA2	Interferon Alpha 2	Protein Coding	2
45	IFNA4	Interferon Alpha 4	Protein Coding	2
46	IFNA5	Interferon Alpha 5	Protein Coding	2
47	IFNA6	Interferon Alpha 6	Protein Coding	2
48	IFNA7	Interferon Alpha 7	Protein Coding	2
49	IFNA8	Interferon Alpha 8	Protein Coding	2
50	IFNA10	Interferon Alpha 10	Protein Coding	2
51	IFNA13	Interferon Alpha 13	Protein Coding	2
52	IFNA14	Interferon Alpha 14	Protein Coding	2
53	IFNA16	Interferon Alpha 16	Protein Coding	2
54	IFNA17	Interferon Alpha 17	Protein Coding	2
55	IFNA21	Interferon Alpha 21	Protein Coding	2
56	IFNAR1	Interferon Alpha And Beta Receptor Subunit 1	Protein Coding	2
57	IFNAR2	Interferon Alpha And Beta Receptor Subunit 2	Protein Coding	2
58	IFNB1	Interferon Beta 1	Protein Coding	2
59	IRF3	Interferon Regulatory Factor 3	Protein Coding	2
60	JAK1	Janus Kinase 1	Protein Coding	2
61	AGRN	Agrin	Protein Coding	2
62	MED11	Mediator Complex Subunit 11	Protein Coding	2
63	MAP1B	Microtubule Associated Protein 1B	Protein Coding	2
64	OAS2	2''-5''-Oligoadenylate Synthetase 2	Protein Coding	2
65	MED31	Mediator Complex Subunit 31	Protein Coding	2
66	HERC5	HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 5	Protein Coding	2
67	TLR7	Toll Like Receptor 7	Protein Coding	2
68	MED15	Mediator Complex Subunit 15	Protein Coding	2
69	MED1	Mediator Complex Subunit 1	Protein Coding	2
70	MED18	Mediator Complex Subunit 18	Protein Coding	2
71	MED9	Mediator Complex Subunit 9	Protein Coding	2
72	MED29	Mediator Complex Subunit 29	Protein Coding	2
73	EIF2AK2	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2	Protein Coding	2
74	MAVS	Mitochondrial Antiviral Signaling Protein	Protein Coding	2
75	RPS27A	Ribosomal Protein S27a	Protein Coding	2
76	SDC1	Syndecan 1	Protein Coding	2
77	SDC2	Syndecan 2	Protein Coding	2
78	SDC4	Syndecan 4	Protein Coding	2
79	IFIH1	Interferon Induced With Helicase C Domain 1	Protein Coding	2
80	STAT2	Signal Transducer And Activator Of Transcription 2	Protein Coding	2
81	MED22	Mediator Complex Subunit 22	Protein Coding	2
82	ELOC	Elongin C	Protein Coding	2
83	ELOB	Elongin B	Protein Coding	2
84	TLR2	Toll Like Receptor 2	Protein Coding	2
85	TLR3	Toll Like Receptor 3	Protein Coding	2
86	TLR4	Toll Like Receptor 4	Protein Coding	2
87	TYK2	Tyrosine Kinase 2	Protein Coding	2
88	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	2
89	UBB	Ubiquitin B	Protein Coding	2
90	UBC	Ubiquitin C	Protein Coding	2
91	TRIM25	Tripartite Motif Containing 25	Protein Coding	2
92	MED28	Mediator Complex Subunit 28	Protein Coding	2
93	CUL5	Cullin 5	Protein Coding	2
94	MED25	Mediator Complex Subunit 25	Protein Coding	2
95	H2BC15	H2B Clustered Histone 15	Protein Coding	2
96	MED10	Mediator Complex Subunit 10	Protein Coding	2
97	BECN1	Beclin 1	Protein Coding	2
98	CCNC	Cyclin C	Protein Coding	2
99	MED30	Mediator Complex Subunit 30	Protein Coding	2
100	UBE2L6	Ubiquitin Conjugating Enzyme E2 L6	Protein Coding	2
101	MED14	Mediator Complex Subunit 14	Protein Coding	2
102	CD14	CD14 Molecule	Protein Coding	2
103	MED21	Mediator Complex Subunit 21	Protein Coding	2
104	MED23	Mediator Complex Subunit 23	Protein Coding	2
105	MED17	Mediator Complex Subunit 17	Protein Coding	2
106	MED26	Mediator Complex Subunit 26	Protein Coding	2
107	MED27	Mediator Complex Subunit 27	Protein Coding	2
108	MED7	Mediator Complex Subunit 7	Protein Coding	2
109	MED20	Mediator Complex Subunit 20	Protein Coding	2
110	ISG15	ISG15 Ubiquitin Like Modifier	Protein Coding	2
111	SDC3	Syndecan 3	Protein Coding	2
112	MED24	Mediator Complex Subunit 24	Protein Coding	2
113	MED12	Mediator Complex Subunit 12	Protein Coding	2
114	MED13	Mediator Complex Subunit 13	Protein Coding	2
115	RBX1	Ring-Box 1	Protein Coding	2
116	EGFR	Epidermal Growth Factor Receptor	Protein Coding	1
117	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	1
118	NCL	Nucleolin	Protein Coding	1
119	RAB5A	RAB5A, Member RAS Oncogene Family	Protein Coding	1
120	RAB5B	RAB5B, Member RAS Oncogene Family	Protein Coding	1
121	RAB5C	RAB5C, Member RAS Oncogene Family	Protein Coding	1

Disorders associated with Respiratory Syncytial Virus Infection Pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Respiratory syncytial virus infectious disease	Direct

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Respiratory Syncytial Virus Infection Pathway

Pathway Network for Respiratory Syncytial Virus Infection Pathway

Pathway network for the Respiratory Syncytial Virus Infection Pathway SuperPath

Member Pathways for Respiratory Syncytial Virus Infection Pathway

Pathways in the Respiratory Syncytial Virus Infection Pathway SuperPath

Gene overlap in member pathways for Respiratory Syncytial Virus Infection Pathway SuperPath

Associated Genes for Respiratory Syncytial Virus Infection Pathway

Associated Disorders for Respiratory Syncytial Virus Infection Pathway

Disorders associated with Respiratory Syncytial Virus Infection Pathway SuperPath

STRING Interaction Network for Respiratory Syncytial Virus Infection Pathway

Sources for Respiratory Syncytial Virus Infection Pathway