Response of Mtb to phagocytosis

Sources:

#	Name	Source	Genes
1	Response of Mtb to phagocytosis	Reactome	ATP6V1H CORO1A CTSG DUSP16 ENO1 GSK3A HGS KPNA1 KPNB1 MAPK1 MAPK3 NOS2 PGK1 RAB5A RAB7A RNF213 RPS27A SFPQ TRIM27 UBA52 UBB UBC VPS33B (see all 23) (see less)
2	Infection with Mycobacterium tuberculosis	Reactome	ATP6V1H B2M CORO1A CTSG DUSP16 ENO1 GSK3A HGS KPNA1 KPNB1 LTF MAPK1 MAPK3 MRC1 NOS2 PGK1 RAB5A RAB7A RNF213 RPS27A SFPQ TLR2 TRIM27 UBA52 UBB UBC VPS33B (see all 27) (see less)
3	Suppression of phagosomal maturation	Reactome	ATP6V1H CORO1A HGS KPNA1 KPNB1 NOS2 RAB5A RAB7A RPS27A UBA52 UBB UBC VPS33B (see all 13) (see less)
4	Prevention of phagosomal-lysosomal fusion	Reactome	CORO1A HGS RAB5A RAB7A RPS27A UBA52 UBB UBC VPS33B (see all 9) (see less)
5	Suppression of apoptosis	Reactome	CTSG GSK3A MAPK1 MAPK3 RNF213 SFPQ TRIM27 (see all 7) (see less)
6	Modulation by Mtb of host immune system	Reactome	B2M MRC1 RPS27A TLR2 UBA52 UBB UBC (see all 7) (see less)
7	Inhibition of nitric oxide production	Reactome	KPNA1 KPNB1 NOS2
8	Suppression of autophagy	Reactome	DUSP16 RAB7A
9	Inhibition of membrane repair	Reactome	HGS

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RPS27A	Ribosomal Protein S27a	Protein Coding	5
2	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	5
3	UBB	Ubiquitin B	Protein Coding	5
4	UBC	Ubiquitin C	Protein Coding	5
5	RAB7A	RAB7A, Member RAS Oncogene Family	Protein Coding	5
6	HGS	Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate	Protein Coding	5
7	CORO1A	Coronin 1A	Protein Coding	4
8	VPS33B	VPS33B Late Endosome And Lysosome Associated	Protein Coding	4
9	KPNA1	Karyopherin Subunit Alpha 1	Protein Coding	4
10	KPNB1	Karyopherin Subunit Beta 1	Protein Coding	4
11	NOS2	Nitric Oxide Synthase 2	Protein Coding	4
12	RAB5A	RAB5A, Member RAS Oncogene Family	Protein Coding	4
13	CTSG	Cathepsin G	Protein Coding	3
14	GSK3A	Glycogen Synthase Kinase 3 Alpha	Protein Coding	3
15	ATP6V1H	ATPase H+ Transporting V1 Subunit H	Protein Coding	3
16	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	3
17	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	3
18	RNF213	Ring Finger Protein 213	Protein Coding	3
19	TRIM27	Tripartite Motif Containing 27	Protein Coding	3
20	SFPQ	Splicing Factor Proline And Glutamine Rich	Protein Coding	3
21	DUSP16	Dual Specificity Phosphatase 16	Protein Coding	3
22	ENO1	Enolase 1	Protein Coding	2
23	PGK1	Phosphoglycerate Kinase 1	Protein Coding	2
24	MRC1	Mannose Receptor C-Type 1	Protein Coding	2
25	B2M	Beta-2-Microglobulin	Protein Coding	2
26	TLR2	Toll Like Receptor 2	Protein Coding	2
27	LTF	Lactotransferrin	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Tuberculosis	Direct

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Response of Mtb to phagocytosis