retinoate biosynthesis I

No Pathway Network information available for retinoate biosynthesis I

#	Name	Source	Genes
1	retinoate biosynthesis I	PubChem	ALDH1A1 ALDH1A2 ALDH1A3 RBP1 RBP4 RDH16 SDR16C5 (see all 7) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SDR16C5	Short Chain Dehydrogenase/Reductase Family 16C Member 5	Protein Coding	1
2	RDH16	Retinol Dehydrogenase 16	Protein Coding	1
3	ALDH1A3	Aldehyde Dehydrogenase 1 Family Member A3	Protein Coding	1
4	ALDH1A2	Aldehyde Dehydrogenase 1 Family Member A2	Protein Coding	1
5	RBP1	Retinol Binding Protein 1	Protein Coding	1
6	RBP4	Retinol Binding Protein 4	Protein Coding	1
7	ALDH1A1	Aldehyde Dehydrogenase 1 Family Member A1	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Macs syndrome	Enrichment	ALDH1A3, RBP4	4.36
2	Microphthalmia	Enrichment	ALDH1A3, RBP4	4.28
3	Microphthalmia/coloboma 10	Enrichment	RBP4	3.29
4	Diaphragmatic hernia 4, with cardiovascular defects	Enrichment	ALDH1A2	3.29
5	Retinal dystrophy, iris coloboma, and comedogenic acne syndrome	Enrichment	RBP4	2.99
6	Microphthalmia, isolated 8	Enrichment	ALDH1A3	2.99
7	Progressive retinal dystrophy due to retinol transport defect	Enrichment	RBP4	2.99
8	Isolated anophthalmia-microphthalmia syndrome	Enrichment	ALDH1A3	2.81
9	Nanophthalmos	Enrichment	ALDH1A3	2.25
10	Microphthalmia/coloboma 12	Enrichment	RBP4	2.17
11	Coloboma of macula	Enrichment	RBP4	2.11
12	Anterior segment dysgenesis	Enrichment	RBP4	2.11
13	Eye disease	Enrichment	RBP4	1.75
14	Autism	Enrichment	ALDH1A3	1.44
15	Hereditary retinal dystrophy	Enrichment	RBP4	0.85
16	Fundus dystrophy	Enrichment	RBP4	0.85

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for retinoate biosynthesis I