Retinoblastoma gene in cancer
Pathways in the Retinoblastoma gene in cancer SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Retinoblastoma gene in cancer | WikiPathways |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | CDC25B | Cell Division Cycle 25B | Protein Coding | 1 |
| 2 | CDK1 | Cyclin Dependent Kinase 1 | Protein Coding | 1 |
| 3 | CCNE2 | Cyclin E2 | Protein Coding | 1 |
| 4 | CCNB2 | Cyclin B2 | Protein Coding | 1 |
| 5 | SMC3 | Structural Maintenance Of Chromosomes 3 | Protein Coding | 1 |
| 6 | CCNE1 | Cyclin E1 | Protein Coding | 1 |
| 7 | CCND3 | Cyclin D3 | Protein Coding | 1 |
| 8 | CCNB1 | Cyclin B1 | Protein Coding | 1 |
| 9 | CCNA2 | Cyclin A2 | Protein Coding | 1 |
| 10 | CDC45 | Cell Division Cycle 45 | Protein Coding | 1 |
| 11 | SMC1A | Structural Maintenance Of Chromosomes 1A | Protein Coding | 1 |
| 12 | CDT1 | Chromatin Licensing And DNA Replication Factor 1 | Protein Coding | 1 |
| 13 | CCDC6 | Coiled-Coil Domain Containing 6 | Protein Coding | 1 |
| 14 | WEE1 | WEE1 G2 Checkpoint Kinase | Protein Coding | 1 |
| 15 | TYMS | Thymidylate Synthetase | Protein Coding | 1 |
| 16 | TTK | TTK Protein Kinase | Protein Coding | 1 |
| 17 | TP53 | Tumor Protein P53 | Protein Coding | 1 |
| 18 | TOP2A | DNA Topoisomerase II Alpha | Protein Coding | 1 |
| 19 | TFDP2 | Transcription Factor Dp-2 | Protein Coding | 1 |
| 20 | TFDP1 | Transcription Factor Dp-1 | Protein Coding | 1 |
| 21 | SUV39H1 | SUV39H1 Histone Lysine Methyltransferase | Protein Coding | 1 |
| 22 | HLTF | Helicase Like Transcription Factor | Protein Coding | 1 |
| 23 | SMARCA2 | SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 2 | Protein Coding | 1 |
| 24 | SKP2 | S-Phase Kinase Associated Protein 2 | Protein Coding | 1 |
| 25 | RRM2 | Ribonucleotide Reductase Regulatory Subunit M2 | Protein Coding | 1 |
| 26 | RRM1 | Ribonucleotide Reductase Catalytic Subunit M1 | Protein Coding | 1 |
| 27 | RPA1 | Replication Protein A1 | Protein Coding | 1 |
| 28 | RFC4 | Replication Factor C Subunit 4 | Protein Coding | 1 |
| 29 | CCND1 | Cyclin D1 | Protein Coding | 1 |
| 30 | RBP1 | Retinol Binding Protein 1 | Protein Coding | 1 |
| 31 | RB1 | RB Transcriptional Corepressor 1 | Protein Coding | 1 |
| 32 | RAF1 | Raf-1 Proto-Oncogene, Serine/Threonine Kinase | Protein Coding | 1 |
| 33 | BARD1 | BRCA1 Associated RING Domain 1 | Protein Coding | 1 |
| 34 | MAPK13 | Mitogen-Activated Protein Kinase 13 | Protein Coding | 1 |
| 35 | PRKDC | Protein Kinase, DNA-Activated, Catalytic Subunit | Protein Coding | 1 |
| 36 | ANLN | Anillin, Actin Binding Protein | Protein Coding | 1 |
| 37 | POLE | DNA Polymerase Epsilon, Catalytic Subunit | Protein Coding | 1 |
| 38 | POLA1 | DNA Polymerase Alpha 1, Catalytic Subunit | Protein Coding | 1 |
| 39 | PCNA | Proliferating Cell Nuclear Antigen | Protein Coding | 1 |
| 40 | ORC1 | Origin Recognition Complex Subunit 1 | Protein Coding | 1 |
| 41 | MYC | MYC Proto-Oncogene, BHLH Transcription Factor | Protein Coding | 1 |
| 42 | MDM2 | MDM2 Proto-Oncogene | Protein Coding | 1 |
| 43 | MCM6 | Minichromosome Maintenance Complex Component 6 | Protein Coding | 1 |
| 44 | MCM4 | Minichromosome Maintenance Complex Component 4 | Protein Coding | 1 |
| 45 | MIR29B2 | MicroRNA 29b-2 | RNA Gene | 1 |
| 46 | STMN1 | Stathmin 1 | Protein Coding | 1 |
| 47 | HMGB2 | High Mobility Group Box 2 | Protein Coding | 1 |
| 48 | HMGB1 | High Mobility Group Box 1 | Protein Coding | 1 |
| 49 | HDAC1 | Histone Deacetylase 1 | Protein Coding | 1 |
| 50 | MSH6 | MutS Homolog 6 | Protein Coding | 1 |
| 51 | SIN3A | SIN3 Transcription Regulator Family Member A | Protein Coding | 1 |
| 52 | ABL1 | ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase | Protein Coding | 1 |
| 53 | KIF4A | Kinesin Family Member 4A | Protein Coding | 1 |
| 54 | FANCG | FA Complementation Group G | Protein Coding | 1 |
| 55 | E2F3 | E2F Transcription Factor 3 | Protein Coding | 1 |
| 56 | E2F2 | E2F Transcription Factor 2 | Protein Coding | 1 |
| 57 | E2F1 | E2F Transcription Factor 1 | Protein Coding | 1 |
| 58 | DNMT1 | DNA Methyltransferase 1 | Protein Coding | 1 |
| 59 | DHFR | Dihydrofolate Reductase | Protein Coding | 1 |
| 60 | CHEK1 | Checkpoint Kinase 1 | Protein Coding | 1 |
| 61 | PLK4 | Polo Like Kinase 4 | Protein Coding | 1 |
| 62 | POLD3 | DNA Polymerase Delta 3, Accessory Subunit | Protein Coding | 1 |
| 63 | SMC2 | Structural Maintenance Of Chromosomes 2 | Protein Coding | 1 |
| 64 | CDKN1B | Cyclin Dependent Kinase Inhibitor 1B | Protein Coding | 1 |
| 65 | CDKN1A | Cyclin Dependent Kinase Inhibitor 1A | Protein Coding | 1 |
| 66 | CDK6 | Cyclin Dependent Kinase 6 | Protein Coding | 1 |
| 67 | CDK4 | Cyclin Dependent Kinase 4 | Protein Coding | 1 |
| 68 | CDK2 | Cyclin Dependent Kinase 2 | Protein Coding | 1 |
| 69 | DCK | Deoxycytidine Kinase | Protein Coding | 1 |
| 70 | SAP30 | Sin3A Associated Protein 30 | Protein Coding | 1 |
| 71 | FAF1 | Fas Associated Factor 1 | Protein Coding | 1 |
| 72 | CDC7 | Cell Division Cycle 7 | Protein Coding | 1 |
| 73 | RFC5 | Replication Factor C Subunit 5 | Protein Coding | 1 |
| 74 | RFC3 | Replication Factor C Subunit 3 | Protein Coding | 1 |
| 75 | RBBP7 | RB Binding Protein 7, Chromatin Remodeling Factor | Protein Coding | 1 |
| 76 | RBBP4 | RB Binding Protein 4, Chromatin Remodeling Factor | Protein Coding | 1 |
| 77 | RABIF | RAB Interacting Factor | Protein Coding | 1 |
| 78 | PRIM1 | DNA Primase Subunit 1 | Protein Coding | 1 |
| 79 | POLE2 | DNA Polymerase Epsilon 2, Accessory Subunit | Protein Coding | 1 |
| 80 | NPAT | Nuclear Protein, Coactivator Of Histone Transcription | Protein Coding | 1 |
| 81 | MCM7 | Minichromosome Maintenance Complex Component 7 | Protein Coding | 1 |
| 82 | MCM3 | Minichromosome Maintenance Complex Component 3 | Protein Coding | 1 |
| 83 | MIR29B1 | MicroRNA 29b-1 | RNA Gene | 1 |
| 84 | CDC25A | Cell Division Cycle 25A | Protein Coding | 1 |
| 85 | PRMT2 | Protein Arginine Methyltransferase 2 | Protein Coding | 1 |
| 86 | H2AZ1 | H2A.Z Variant Histone 1 | Protein Coding | 1 |
Disorders associated with Retinoblastoma gene in cancer SuperPath
according to GeneCards Suite gene sharing