Rett syndrome causing genes

No Pathway Network information available for Rett syndrome causing genes

Pathways in the Rett syndrome causing genes SuperPath

#	Name	Source	Genes
1	Rett syndrome causing genes	WikiPathways	ACTL6B BRAF CDKL5 CECR2 CHD4 CRK EIF2B2 FOXG1 GABBR2 GABRA3 GABRD GNAO1 GPS2 GRIN2A GRIN2B HAP1 HDAC1 HDAC5 HDAC8 HIVEP2 HTT IMPDH2 KCNJ10 KDM5B MECP2 MEF2C NCOR1 NCOR2 RHOBTB2 SATB2 SCN1A SCN2A SCN8A SHANK3 SMARCA1 SMARCA2 SMARCA4 SMC1A SRRM3 STXBP1 SYNE2 SYNGAP1 TAF1B TBL1X TBL1XR1 TCF4 TRRAP XAB2 (see all 48) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	HDAC8	Histone Deacetylase 8	Protein Coding	1
2	NCOR2	Nuclear Receptor Corepressor 2	Protein Coding	1
3	NCOR1	Nuclear Receptor Corepressor 1	Protein Coding	1
4	GABBR2	Gamma-Aminobutyric Acid Type B Receptor Subunit 2	Protein Coding	1
5	EIF2B2	Eukaryotic Translation Initiation Factor 2B Subunit Beta	Protein Coding	1
6	SYNGAP1	Synaptic Ras GTPase Activating Protein 1	Protein Coding	1
7	SHANK3	SH3 And Multiple Ankyrin Repeat Domains 3	Protein Coding	1
8	TRRAP	Transformation/Transcription Domain Associated Protein	Protein Coding	1
9	SMC1A	Structural Maintenance Of Chromosomes 1A	Protein Coding	1
10	TBL1XR1	TBL1X/Y Related 1	Protein Coding	1
11	TCF4	Transcription Factor 4	Protein Coding	1
12	TBL1X	Transducin Beta Like 1 X-Linked	Protein Coding	1
13	STXBP1	Syntaxin Binding Protein 1	Protein Coding	1
14	CDKL5	Cyclin Dependent Kinase Like 5	Protein Coding	1
15	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
16	SMARCA4	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 4	Protein Coding	1
17	SMARCA2	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 2	Protein Coding	1
18	SMARCA1	SNF2 Related Chromatin Remodeling ATPase 1	Protein Coding	1
19	SCN8A	Sodium Voltage-Gated Channel Alpha Subunit 8	Protein Coding	1
20	SCN2A	Sodium Voltage-Gated Channel Alpha Subunit 2	Protein Coding	1
21	SCN1A	Sodium Voltage-Gated Channel Alpha Subunit 1	Protein Coding	1
22	ACTL6B	Actin Like 6B	Protein Coding	1
23	MEF2C	Myocyte Enhancer Factor 2C	Protein Coding	1
24	MECP2	Methyl-CpG Binding Protein 2	Protein Coding	1
25	KCNJ10	Potassium Inwardly Rectifying Channel Subfamily J Member 10	Protein Coding	1
26	IMPDH2	Inosine Monophosphate Dehydrogenase 2	Protein Coding	1
27	HIVEP2	HIVEP Zinc Finger 2	Protein Coding	1
28	HDAC1	Histone Deacetylase 1	Protein Coding	1
29	HTT	Huntingtin	Protein Coding	1
30	GRIN2B	Glutamate Ionotropic Receptor NMDA Type Subunit 2B	Protein Coding	1
31	GRIN2A	Glutamate Ionotropic Receptor NMDA Type Subunit 2A	Protein Coding	1
32	GNAO1	G Protein Subunit Alpha O1	Protein Coding	1
33	CECR2	CECR2 Histone Acetyl-Lysine Reader	Protein Coding	1
34	GABRD	Gamma-Aminobutyric Acid Type A Receptor Subunit Delta	Protein Coding	1
35	GABRA3	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha3	Protein Coding	1
36	SATB2	SATB Homeobox 2	Protein Coding	1
37	SYNE2	Spectrin Repeat Containing Nuclear Envelope Protein 2	Protein Coding	1
38	RHOBTB2	Rho Related BTB Domain Containing 2	Protein Coding	1
39	FOXG1	Forkhead Box G1	Protein Coding	1
40	CRK	CRK Proto-Oncogene, Adaptor Protein	Protein Coding	1
41	CHD4	Chromodomain Helicase DNA Binding Protein 4	Protein Coding	1
42	KDM5B	Lysine Demethylase 5B	Protein Coding	1
43	HDAC5	Histone Deacetylase 5	Protein Coding	1
44	TAF1B	TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit B	Protein Coding	1
45	HAP1	Huntingtin Associated Protein 1	Protein Coding	1
46	XAB2	XPA Binding Protein 2~Name Same As:- HGNC:14337	Protein Coding	1
47	GPS2	G Protein Pathway Suppressor 2	Protein Coding	1
48	SRRM3	Serine/Arginine Repetitive Matrix 3	Protein Coding	1

Disorders associated with Rett syndrome causing genes SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Microcephaly	Enrichment	GNAO1, GRIN2B, HDAC8, KCNJ10, MECP2, SATB2, SCN1A, SMC1A, STXBP1, SYNGAP1, TCF4	11.74
2	Autism spectrum disorder	Enrichment	ACTL6B, GRIN2B, KDM5B, MECP2, MEF2C, SATB2, SCN2A, SHANK3, STXBP1, TCF4	11.06
3	Rett syndrome	Enrichment	CDKL5, FOXG1, GABBR2, MECP2, RHOBTB2	10.57
4	Rett syndrome, congenital variant	Enrichment	CDKL5, FOXG1, GABBR2, MECP2, SMC1A	10.39
5	West syndrome	Enrichment	CDKL5, GNAO1, GRIN2B, SCN1A, SCN2A, SCN8A, STXBP1	9.81
6	Stereotypic movement disorder	Enrichment	CDKL5, FOXG1, MECP2, SYNGAP1, TCF4	9.23
7	Developmental and epileptic encephalopathy	Enrichment	CDKL5, GNAO1, SCN1A, SCN2A, SCN8A, STXBP1	8.59
8	Focal epilepsy	Enrichment	CDKL5, MECP2, SCN2A, SCN8A	8.32
9	Epilepsy	Enrichment	GRIN2A, GRIN2B, MECP2, SCN1A, SCN2A, SCN8A	8.30
10	Autism	Enrichment	ACTL6B, CDKL5, MECP2, SCN1A, SCN2A, SCN8A, STXBP1	8.26
11	Congenital nervous system abnormality	Enrichment	CDKL5, EIF2B2, FOXG1, GNAO1, KCNJ10, MECP2, SMC1A	7.08
12	Nervous system disease	Enrichment	CDKL5, EIF2B2, FOXG1, GNAO1, KCNJ10, MECP2, SMC1A	7.08
13	Autosomal dominant non-syndromic intellectual disability	Enrichment	GRIN2B, HIVEP2, KDM5B, SCN8A, TCF4	6.07
14	Undetermined early-onset epileptic encephalopathy	Enrichment	ACTL6B, FOXG1, GABBR2, SCN1A, SCN8A	5.83
15	Developmental and epileptic encephalopathy 1	Enrichment	CDKL5, GNAO1, SCN1A, SCN8A	5.78
16	Complex neurodevelopmental disorder	Enrichment	ACTL6B, GRIN2B, HTT, SCN2A, SCN8A, SYNGAP1	5.33
17	Dystonia	Enrichment	IMPDH2, MECP2, RHOBTB2, SATB2	5.18
18	Developmental and epileptic encephalopathy 76	Enrichment	ACTL6B, SCN1A	4.91
19	Bruxism	Enrichment	CDKL5, MECP2	4.91
20	Generalized epilepsy with febrile seizures plus	Enrichment	GABRD, SCN1A, SCN2A	4.83
21	Early infantile developmental and epileptic encephalopathy	Enrichment	CDKL5, GNAO1, SCN2A	4.49
22	Nicolaides-baraitser syndrome	Enrichment	CDKL5, SMARCA2	4.14
23	Developmental and epileptic encephalopathy 4	Enrichment	CDKL5, STXBP1	4.14
24	Smarca2-related nicolaides-baraitser syndrome	Enrichment	CDKL5, SMARCA2	4.14
25	Self-limited infantile epilepsy	Enrichment	SCN2A, SCN8A	3.91
26	Angelman syndrome	Enrichment	CDKL5, MECP2	3.74
27	Alternating hemiplegia of childhood	Enrichment	RHOBTB2, SCN2A	3.47
28	Choreatic disease	Enrichment	GNAO1, RHOBTB2	3.47
29	Cerebral palsy	Enrichment	GRIN2B, SMARCA4, SYNE2	3.46
30	Benign epilepsy with centrotemporal spikes	Enrichment	GRIN2A, SCN1A, SCN2A	3.39
31	Cornelia de lange syndrome 1	Enrichment	HDAC8, SMC1A	3.36
32	Myoclonic-atonic epilepsy	Enrichment	SCN1A, SYNGAP1	3.36
33	Developmental and epileptic encephalopathy 14	Enrichment	SCN1A, SCN2A	3.36
34	Ventricular septal defect	Enrichment	BRAF, SMARCA4	3.36
35	Cornelia de lange syndrome	Enrichment	HDAC8, SMC1A	3.36
36	Centralopathic epilepsy	Enrichment	GRIN2A, SCN1A, SCN2A	3.33
37	Dravet syndrome	Enrichment	SCN1A, SCN2A	3.27
38	Atrial heart septal defect	Enrichment	HDAC8, SMARCA4	3.18
39	Movement disease	Enrichment	GNAO1, SCN2A	3.18
40	Interatrial communication	Enrichment	HDAC8, SMARCA4	3.18
41	Spastic ataxia	Enrichment	SCN2A, STXBP1, SYNE2	3.07
42	Cleft palate, isolated	Enrichment	SATB2, SMARCA4	2.79
43	Diffuse large b-cell lymphoma	Enrichment	BRAF, TBL1XR1	2.70
44	Epilepsy, focal, with speech disorder and with or without impaired intellectual development	Enrichment	GRIN2A	2.45
45	Developmental and epileptic encephalopathy 85 with or without midline brain defects	Enrichment	SMC1A	2.45
46	Hypothyroidism, congenital, nongoitrous, 8	Enrichment	TBL1X	2.45
47	Facial hypertrichosis	Enrichment	MECP2	2.45
48	Noonan syndrome 7	Enrichment	BRAF	2.45
49	Leopard syndrome 3	Enrichment	BRAF	2.45
50	Developmental and epileptic encephalopathy 11	Enrichment	SCN2A	2.45
51	Neurodevelopmental disorder with involuntary movements	Enrichment	GNAO1	2.45
52	Developmental and epileptic encephalopathy 27	Enrichment	GRIN2B	2.45
53	Intellectual developmental disorder with severe speech and ambulation defects	Enrichment	ACTL6B	2.45
54	Intellectual developmental disorder, x-linked, syndromic, lubs type	Enrichment	MECP2	2.45
55	Impdh2 enzyme activity, variation in	Enrichment	IMPDH2	2.45
56	Autism x-linked 3	Enrichment	MECP2	2.45
57	Cornelia de lange syndrome 5	Enrichment	HDAC8	2.45
58	Neurodevelopmental disorder with poor language and loss of hand skills	Enrichment	GABBR2	2.45
59	Developmental and epileptic encephalopathy 59	Enrichment	GABBR2	2.45
60	Myoclonus, familial, 2	Enrichment	SCN8A	2.45
61	Epilepsy, x-linked 2, with or without impaired intellectual development and dysmorphic features	Enrichment	GABRA3	2.45
62	Epilepsy, idiopathic generalized 10	Enrichment	GABRD	2.45
63	Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Enrichment	MEF2C	2.45
64	Seizures, sensorineural deafness, ataxia, impaired intellectual development, and electrolyte imbalance	Enrichment	KCNJ10	2.45
65	Developmental and epileptic encephalopathy 17	Enrichment	GNAO1	2.45
66	Lymphangioma	Enrichment	BRAF	2.45
67	Phace association	Enrichment	BRAF	2.45
68	Intellectual developmental disorder, autosomal recessive 65	Enrichment	KDM5B	2.45
69	Episodic ataxia, type 9	Enrichment	SCN2A	2.45
70	Intellectual developmental disorder, autosomal dominant 6, with or without seizures	Enrichment	GRIN2B	2.45
71	Emery-dreifuss muscular dystrophy 5, autosomal dominant	Enrichment	SYNE2	2.45
72	Benign familial infantile epilepsy	Enrichment	SCN2A	2.45
73	Syndromic x-linked intellectual disability lubs type	Enrichment	MECP2	2.45
74	Cdkl5 deficiency disorder	Enrichment	CDKL5	2.45
75	Corneal dystrophy, fuchs endothelial, 3	Enrichment	TCF4	2.45
76	Schizophrenia 15	Enrichment	SHANK3	2.45
77	Smarca4-deficient sarcoma of thorax	Enrichment	SMARCA4	2.45
78	Ovarian small cell carcinoma	Enrichment	SMARCA4	2.45
79	Deafness, autosomal dominant 75	Enrichment	TRRAP	2.45
80	Lopes-maciel-rodan syndrome	Enrichment	HTT	2.45
81	Developmental and epileptic encephalopathy 64	Enrichment	RHOBTB2	2.45
82	Blepharophimosis-impaired intellectual development syndrome	Enrichment	SMARCA2	2.45
83	Developmental delay with or without dysmorphic facies and autism	Enrichment	TRRAP	2.45
84	Leukoencephalopathy with vanishing white matter 2	Enrichment	EIF2B2	2.45
85	Grin2b-related neurodevelopmental disorder	Enrichment	GRIN2B	2.45
86	Landau-kleffner syndrome	Enrichment	GRIN2A	2.45
87	5q14.3 microdeletion syndrome	Enrichment	MEF2C	2.45
88	Mutism	Enrichment	SHANK3	2.45
89	Complete atrioventricular septal defect without ventricular hypoplasia	Enrichment	MEF2C	2.45
90	Foxg1 syndrome due to intragenic alteration	Enrichment	FOXG1	2.45
91	Syringocystadenoma papilliferum	Enrichment	BRAF	2.45
92	Foxg1 syndrome due to 14q12 microdeletion	Enrichment	FOXG1	2.45
93	Ganglioglioma	Enrichment	BRAF	2.45
94	Juvenile huntington disease	Enrichment	HTT	2.45
95	Nongerminomatous germ cell tumor	Enrichment	BRAF	2.45
96	Early-onset epileptic encephalopathy and intellectual disability due to grin2a mutation	Enrichment	GRIN2A	2.45
97	Grin2a-related disorders	Enrichment	GRIN2A	2.45
98	Phace syndrome	Enrichment	BRAF	2.45
99	Gnao1-related disorder	Enrichment	GNAO1	2.45
100	Mef2c-related disorder	Enrichment	MEF2C	2.45
101	Classic hairy cell leukemia	Enrichment	BRAF	2.45
102	Rare renal tubular disease	Enrichment	KCNJ10	2.45
103	Strabismus	Enrichment	FOXG1, STXBP1	2.39
104	Encephalopathy, neonatal severe, due to mecp2 mutations	Enrichment	MECP2	2.15
105	Cornelia de lange syndrome 2	Enrichment	SMC1A	2.15
106	Pulmonic stenosis	Enrichment	BRAF	2.15
107	Retinoschisis 1, x-linked, juvenile	Enrichment	CDKL5	2.15
108	Seizures, benign familial infantile, 3	Enrichment	SCN2A	2.15
109	Rhabdoid tumor predisposition syndrome 2	Enrichment	SMARCA4	2.15
110	Intellectual developmental disorder, autosomal recessive 5	Enrichment	SYNGAP1	2.15
111	Sifrim-hitz-weiss syndrome	Enrichment	CHD4	2.15
112	Intellectual developmental disorder, autosomal dominant 43	Enrichment	HIVEP2	2.15
113	Migraine, familial hemiplegic, 3	Enrichment	SCN1A	2.15
114	Syndactyly, type iii	Enrichment	HDAC8	2.15
115	Cognitive impairment with or without cerebellar ataxia	Enrichment	SCN8A	2.15
116	Developmental and epileptic encephalopathy 6b	Enrichment	SCN1A	2.15
117	Intellectual developmental disorder, x-linked, syndromic 13	Enrichment	MECP2	2.15
118	Wilson-turner syndrome	Enrichment	HDAC8	2.15
119	Rhabdoid tumor predisposition syndrome	Enrichment	SMARCA4	2.15
120	Intellectual developmental disorder, autosomal dominant 21	Enrichment	GRIN2A	2.15
121	X-linked intellectual disability-psychosis-macroorchidism syndrome	Enrichment	MECP2	2.15
122	Benign familial neonatal epilepsy	Enrichment	SCN2A	2.15
123	Developmental and epileptic encephalopathy 30	Enrichment	SCN2A	2.15
124	Phelan-mcdermid syndrome	Enrichment	SHANK3	2.15
125	Psychotic disorder	Enrichment	SHANK3	2.15
126	Otosclerosis 12	Enrichment	SMARCA4	2.15
127	Coffin-siris syndrome 4	Enrichment	SMARCA4	2.15
128	Scn1a seizure disorders	Enrichment	SCN1A	2.15
129	Seizures, benign familial infantile, 5	Enrichment	SCN8A	2.15
130	9q33.3q34.11 microdeletion syndrome	Enrichment	STXBP1	2.15
131	Blepharophimosis - intellectual disability syndrome	Enrichment	SMARCA2	2.15
132	Malignant migrating partial seizures of infancy	Enrichment	SCN2A	2.15
133	Rolandic epilepsy-speech dyspraxia syndrome	Enrichment	GRIN2A	2.15
134	Benign neonatal seizures	Enrichment	SCN2A	2.15
135	Retinoschisis	Enrichment	CDKL5	2.15
136	Progressive bulbar palsy	Enrichment	MECP2	2.15
137	Epilepsy-aphasia spectrum	Enrichment	GRIN2A	2.15
138	Non-syndromic x-linked intellectual disability	Enrichment	MECP2, SMARCA1	2.15
139	Laryngomalacia	Enrichment	MECP2	1.98
140	Dystonia 12	Enrichment	SCN2A	1.98
141	Ataxia-telangiectasia	Enrichment	BRAF	1.98
142	Pierpont syndrome	Enrichment	TBL1XR1	1.98
143	Langerhans cell histiocytosis	Enrichment	BRAF	1.98
144	Glass syndrome	Enrichment	SATB2	1.98
145	Generalized epilepsy with febrile seizures plus, type 1	Enrichment	SCN1A	1.98
146	Intellectual developmental disorder, autosomal dominant 5	Enrichment	SYNGAP1	1.98
147	Generalized epilepsy with febrile seizures plus, type 2	Enrichment	SCN1A	1.98
148	Developmental and epileptic encephalopathy 13	Enrichment	SCN8A	1.98
149	Tethered spinal cord syndrome	Enrichment	BRAF	1.98
150	Intellectual developmental disorder, autosomal dominant 41	Enrichment	TBL1XR1	1.98
151	Gtp cyclohydrolase 1-deficient dopa-responsive dystonia	Enrichment	IMPDH2	1.98
152	Thyrotoxic periodic paralysis	Enrichment	GABRA3	1.98
153	Hereditary episodic ataxia	Enrichment	SCN2A	1.98
154	Episodic kinesigenic dyskinesia 1	Enrichment	KCNJ10	1.85
155	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF	1.85
156	Huntington disease	Enrichment	HTT	1.85
157	Thyroid cancer, nonmedullary, 1	Enrichment	BRAF	1.85
158	Astigmatism	Enrichment	GRIN2B	1.85
159	Developmental and epileptic encephalopathy 2	Enrichment	CDKL5	1.85
160	Lipodystrophy, congenital generalized, type 2	Enrichment	ACTL6B	1.85
161	Pitt-hopkins syndrome	Enrichment	TCF4	1.85
162	Developmental and epileptic encephalopathy 12	Enrichment	SCN2A	1.85
163	Tobacco addiction	Enrichment	GABBR2	1.85
164	Blepharophimosis	Enrichment	SMARCA2	1.85
165	Cardiofaciocutaneous syndrome	Enrichment	BRAF	1.85
166	Craniopharyngioma	Enrichment	BRAF	1.85
167	Noonan syndrome with multiple lentigines	Enrichment	BRAF	1.85
168	Newborn respiratory distress syndrome	Enrichment	BRAF	1.85
169	Episodic ataxia	Enrichment	SCN2A	1.85
170	Familial or sporadic hemiplegic migraine	Enrichment	SCN1A	1.85
171	Sick sinus syndrome	Enrichment	MECP2	1.85
172	Myeloma, multiple	Enrichment	BRAF, NCOR2	1.78
173	Deafness, autosomal recessive 4, with enlarged vestibular aqueduct	Enrichment	KCNJ10	1.76
174	Convulsions, familial infantile, with paroxysmal choreoathetosis	Enrichment	SCN8A	1.76
175	Cholangitis, primary sclerosing	Enrichment	TCF4	1.76
176	Fuchs' endothelial dystrophy	Enrichment	TCF4	1.76
177	Spastic diplegia	Enrichment	KCNJ10	1.76
178	Sleep disorder	Enrichment	GRIN2B	1.76
179	Emery-dreifuss muscular dystrophy 2, autosomal dominant	Enrichment	SYNE2	1.68
180	Wilms tumor 5	Enrichment	BRAF	1.68
181	Pendred syndrome	Enrichment	KCNJ10	1.68
182	Wiedemann-steiner syndrome	Enrichment	SMC1A	1.68
183	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF	1.61
184	Leukoencephalopathy with vanishing white matter 1	Enrichment	EIF2B2	1.61
185	Gallbladder cancer	Enrichment	BRAF	1.61
186	Pilomyxoid astrocytoma	Enrichment	BRAF	1.61
187	Follicular thyroid carcinoma	Enrichment	BRAF	1.61
188	Melanocytic nevus syndrome, congenital	Enrichment	BRAF	1.55
189	Spastic paraplegia 4, autosomal dominant	Enrichment	TCF4	1.55
190	Fanconi anemia, complementation group c	Enrichment	HDAC8	1.55
191	Lymphoma, non-hodgkin, familial	Enrichment	BRAF	1.55
192	Lennox-gastaut syndrome	Enrichment	SCN1A	1.55
193	Leukoencephalopathy with vanishing white matter 5	Enrichment	EIF2B2	1.55
194	Neuroblastoma	Enrichment	SMARCA4	1.55
195	Cardiomyopathy, familial hypertrophic, 4	Enrichment	BRAF	1.50
196	Leukoencephalopathy with vanishing white matter	Enrichment	EIF2B2	1.50
197	Primary hyperaldosteronism	Enrichment	BRAF	1.50
198	Optic nerve disease	Enrichment	FOXG1	1.46
199	Melanoma	Enrichment	BRAF	1.46
200	Epilepsy, myoclonic juvenile	Enrichment	GABRD	1.42
201	Epilepsy, idiopathic generalized	Enrichment	GABRD	1.42
202	Lung non-small cell carcinoma	Enrichment	BRAF	1.42
203	Epicanthus	Enrichment	TCF4	1.38
204	Lip and oral cavity carcinoma	Enrichment	BRAF	1.38
205	Hypercholesterolemia, familial, 1	Enrichment	SMARCA4	1.35
206	Acute promyelocytic leukemia	Enrichment	TBL1XR1	1.35
207	Premature menopause	Enrichment	EIF2B2	1.35
208	Chromosome 1p36 deletion syndrome	Enrichment	GABRD	1.35
209	Lung cancer susceptibility 3	Enrichment	BRAF	1.31
210	Pituitary stalk interruption syndrome	Enrichment	SMARCA2	1.31
211	Coffin-siris syndrome 1	Enrichment	SMARCA4	1.29
212	Wilms tumor 1	Enrichment	BRAF	1.29
213	Familial hypercholesterolemia	Enrichment	SMARCA4	1.29
214	Rare genetic intellectual disability	Enrichment	GNAO1	1.29
215	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF	1.29
216	Isolated congenital microcephaly	Enrichment	FOXG1	1.26
217	Melanoma, cutaneous malignant 1	Enrichment	BRAF	1.23
218	Dandy-walker syndrome	Enrichment	BRAF	1.23
219	Sudden infant death syndrome	Enrichment	SCN1A	1.23
220	Polycystic kidney disease	Enrichment	HDAC8	1.21
221	Semilobar holoprosencephaly	Enrichment	SMC1A	1.21
222	Arteriovenous malformations of the brain	Enrichment	BRAF	1.19
223	Craniosynostosis	Enrichment	GRIN2B	1.16
224	Lissencephaly	Enrichment	FOXG1	1.14
225	Attention deficit-hyperactivity disorder	Enrichment	MECP2	1.12
226	Noonan syndrome 1	Enrichment	BRAF	1.11
227	Brittle bone disorder	Enrichment	EIF2B2	1.11
228	Malaria	Enrichment	SCN8A	1.11
229	Scoliosis	Enrichment	GRIN2B	1.09
230	Rasopathy	Enrichment	BRAF	1.05
231	Differentiated thyroid carcinoma	Enrichment	BRAF	1.01
232	Lung cancer	Enrichment	BRAF	0.97
233	Fetal akinesia deformation sequence 1	Enrichment	SCN8A	0.91
234	Systemic lupus erythematosus	Enrichment	MECP2	0.89
235	Distal arthrogryposis	Enrichment	SCN8A	0.86
236	Body mass index quantitative trait locus 11	Enrichment	SCN1A	0.79
237	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	TRRAP	0.77
238	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	MEF2C	0.73
239	Autosomal recessive non-syndromic intellectual disability	Enrichment	KDM5B	0.73
240	Primary ovarian insufficiency	Enrichment	EIF2B2	0.72
241	Dilated cardiomyopathy	Enrichment	BRAF	0.61
242	Colorectal cancer	Enrichment	BRAF	0.57
243	Inherited cancer-predisposing syndrome	Enrichment	SMARCA4	0.43
244	Hereditary retinal dystrophy	Enrichment	CDKL5	0.19
245	Fundus dystrophy	Enrichment	CDKL5	0.19

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Rett syndrome causing genes

Pathway Network for Rett syndrome causing genes

Member Pathways for Rett syndrome causing genes

Pathways in the Rett syndrome causing genes SuperPath

Associated Genes for Rett syndrome causing genes

Associated Disorders for Rett syndrome causing genes

Disorders associated with Rett syndrome causing genes SuperPath

STRING Interaction Network for Rett syndrome causing genes

Sources for Rett syndrome causing genes