RHO GTPases activate KTN1

No Pathway Network information available for RHO GTPases activate KTN1

Pathways in the RHO GTPases activate KTN1 SuperPath

#	Name	Source	Genes
1	RHO GTPases activate KTN1	Reactome	CDC42 KIF5A KIF5B KLC1 KLC2 KLC3 KLC4 KTN1 RAC1 RHOA RHOG (see all 11) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	KLC3	Kinesin Light Chain 3	Protein Coding	1
2	KIF5A	Kinesin Family Member 5A	Protein Coding	1
3	KIF5B	Kinesin Family Member 5B	Protein Coding	1
4	KLC1	Kinesin Light Chain 1	Protein Coding	1
5	RHOA	Ras Homolog Family Member A	Protein Coding	1
6	KTN1	Kinectin 1	Protein Coding	1
7	RHOG	Ras Homolog Family Member G	Protein Coding	1
8	RAC1	Rac Family Small GTPase 1	Protein Coding	1
9	KLC2	Kinesin Light Chain 2	Protein Coding	1
10	KLC4	Kinesin Light Chain 4	Protein Coding	1
11	CDC42	Cell Division Cycle 42	Protein Coding	1

Disorders associated with RHO GTPases activate KTN1 SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Spastic paraplegia 10, autosomal dominant	Enrichment	KIF5A	3.09
2	Myoclonus, intractable, neonatal	Enrichment	KIF5A	3.09
3	Amyotrophic lateral sclerosis 25	Enrichment	KIF5A	3.09
4	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	3.09
5	Takenouchi-kosaki syndrome	Enrichment	CDC42	3.09
6	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	3.09
7	Neurodegeneration, early-childhood-onset, with retinitis pigmentosa, sensorineural hearing loss, and demyelinating peripheral neuropathy	Enrichment	KLC4	3.09
8	Nocarh syndrome	Enrichment	CDC42	3.09
9	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	3.09
10	Autosomal dominant charcot-marie-tooth disease type 2 due to kif5a mutation	Enrichment	KIF5A	3.09
11	Spastic paraplegia, optic atrophy, and neuropathy	Enrichment	KLC2	2.79
12	Melanoma, cutaneous malignant 6	Enrichment	KLC1	2.79
13	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	2.79
14	Frontotemporal dementia and/or amyotrophic lateral sclerosis 4	Enrichment	KIF5A	2.79
15	Immune system disease	Enrichment	CDC42	2.79
16	Demyelinating polyneuropathy	Enrichment	KIF5A	2.79
17	Skeletal muscle disease	Enrichment	KIF5B	2.79
18	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CDC42	2.49
19	Kearns-sayre syndrome	Enrichment	KIF5B	2.39
20	Hemihyperplasia, isolated	Enrichment	RHOA	2.31
21	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	2.14
22	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	KIF5A	1.82
23	Attention deficit-hyperactivity disorder	Enrichment	KIF5B	1.75
24	Auditory neuropathy	Enrichment	KIF5A	1.68
25	Peripheral nervous system disease	Enrichment	KIF5A	1.59
26	Neuropathy	Enrichment	KIF5A	1.59
27	Hereditary spastic paraplegia	Enrichment	KIF5A	1.47
28	Hypertrophic cardiomyopathy	Enrichment	KIF5B	1.46
29	Breast cancer	Enrichment	KLC1	1.23
30	Dilated cardiomyopathy	Enrichment	KIF5B	1.20

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

RHO GTPases activate KTN1

Pathway Network for RHO GTPases activate KTN1

Member Pathways for RHO GTPases activate KTN1

Pathways in the RHO GTPases activate KTN1 SuperPath

Associated Genes for RHO GTPases activate KTN1

Associated Disorders for RHO GTPases activate KTN1

Disorders associated with RHO GTPases activate KTN1 SuperPath

STRING Interaction Network for RHO GTPases activate KTN1

Sources for RHO GTPases activate KTN1