RHO GTPases Activate Rhotekin and Rhophilins
Pathways in the RHO GTPases Activate Rhotekin and Rhophilins SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | RHO GTPases Activate Rhotekin and Rhophilins | Reactome |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | RHPN1 | Rhophilin Rho GTPase Binding Protein 1 | Protein Coding | 1 |
| 2 | TAX1BP3 | Tax1 Binding Protein 3 | Protein Coding | 1 |
| 3 | RHOA | Ras Homolog Family Member A | Protein Coding | 1 |
| 4 | RHOB | Ras Homolog Family Member B | Protein Coding | 1 |
| 5 | RHOC | Ras Homolog Family Member C | Protein Coding | 1 |
| 6 | ROPN1 | Rhophilin Associated Tail Protein 1 | Protein Coding | 1 |
| 7 | RTKN | Rhotekin | Protein Coding | 1 |
| 8 | LIN7B | Lin-7 Cell Polarity Scaffold B | Protein Coding | 1 |
| 9 | RHPN2 | Rhophilin Rho GTPase Binding Protein 2 | Protein Coding | 1 |
Disorders associated with RHO GTPases Activate Rhotekin and Rhophilins SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies | Enrichment | RHOA | 3.18 |
| 2 | Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies | Enrichment | RHOA | 3.18 |
| 3 | Hemihyperplasia, isolated | Enrichment | RHOA | 2.40 |
