RHOD GTPase cycle

No Pathway Network information available for RHOD GTPase cycle

Pathways in the RHOD GTPase cycle SuperPath

#	Name	Source	Genes
1	RHOD GTPase cycle	Reactome	ACTN1 ADD3 AKAP12 ANKFY1 ARHGAP1 ARHGAP12 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 BUB1B-PAK6 CAPZB CAV1 CPNE8 DBN1 DEPDC1B DIAPH1 DIAPH2 DIAPH3 EFHD2 EMD ESYT1 FILIP1 GOLGA8R HINT2 LBR LEMD3 LMAN1 LMNB1 MCAM MOSPD2 PAK5 PAK6 PGRMC2 PIK3R1 PIK3R2 PLXNA1 PLXNB1 RAB7A RACGAP1 RHOD SLC4A7 STBD1 STEAP3 TMPO TOR1AIP1 VAMP3 VANGL1 VAPB VRK2 WHAMM (see all 54) (see less)
2	RHOF GTPase cycle	Reactome	ACTB ACTN1 ADD3 AKAP12 ARHGAP1 ARHGAP12 ARHGAP21 ARHGAP32 ARHGAP39 ARHGAP5 BAIAP2L1 BAIAP2L2 BASP1 CAPZB CAV1 DEPDC1B DIAPH1 DIAPH2 DIAPH3 ESYT1 FAM169A FARP1 LMNB1 MCAM MTMR1 MYO9B PIK3R1 PIK3R2 POTEE RAB7A RHOF SENP1 SLC4A7 SNAP23 SOWAHC SRGAP2 STEAP3 SYDE1 TMPO TOR1AIP1 VAMP3 VANGL1 (see all 42) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ADD3	Adducin 3	Protein Coding	2
2	DIAPH1	Diaphanous Related Formin 1	Protein Coding	2
3	DIAPH2	Diaphanous Related Formin 2	Protein Coding	2
4	ESYT1	Extended Synaptotagmin 1	Protein Coding	2
5	TOR1AIP1	Torsin 1A Interacting Protein 1	Protein Coding	2
6	ARHGAP1	Rho GTPase Activating Protein 1	Protein Coding	2
7	ARHGAP5	Rho GTPase Activating Protein 5	Protein Coding	2
8	LMNB1	Lamin B1	Protein Coding	2
9	MCAM	Melanoma Cell Adhesion Molecule	Protein Coding	2
10	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	2
11	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	2
12	STEAP3	STEAP3 Metalloreductase	Protein Coding	2
13	DEPDC1B	DEP Domain Containing 1B	Protein Coding	2
14	ARHGAP21	Rho GTPase Activating Protein 21	Protein Coding	2
15	TMPO	Thymopoietin	Protein Coding	2
16	RAB7A	RAB7A, Member RAS Oncogene Family	Protein Coding	2
17	ARHGAP39	Rho GTPase Activating Protein 39	Protein Coding	2
18	DIAPH3	Diaphanous Related Formin 3	Protein Coding	2
19	VANGL1	VANGL Planar Cell Polarity Protein 1	Protein Coding	2
20	CAPZB	Capping Actin Protein Of Muscle Z-Line Subunit Beta	Protein Coding	2
21	CAV1	Caveolin 1	Protein Coding	2
22	ACTN1	Actinin Alpha 1	Protein Coding	2
23	VAMP3	Vesicle Associated Membrane Protein 3	Protein Coding	2
24	ARHGAP12	Rho GTPase Activating Protein 12	Protein Coding	2
25	SLC4A7	Solute Carrier Family 4 Member 7	Protein Coding	2
26	AKAP12	A-Kinase Anchoring Protein 12	Protein Coding	2
27	ARHGAP32	Rho GTPase Activating Protein 32	Protein Coding	2
28	GOLGA8R	Golgin A8 Family Member R	Protein Coding	1
29	PGRMC2	Progesterone Receptor Membrane Component 2	Protein Coding	1
30	BUB1B-PAK6	BUB1B-PAK6 Readthrough	Protein Coding	1
31	WHAMM	WASP Homolog Associated With Actin, Golgi Membranes And Microtubules	Protein Coding	1
32	CPNE8	Copine 8	Protein Coding	1
33	MOSPD2	Motile Sperm Domain Containing 2	Protein Coding	1
34	DBN1	Drebrin 1	Protein Coding	1
35	EMD	Emerin	Protein Coding	1
36	ARHGAP26	Rho GTPase Activating Protein 26	Protein Coding	1
37	LEMD3	LEM Domain Containing 3	Protein Coding	1
38	FILIP1	Filamin A Interacting Protein 1	Protein Coding	1
39	ARHGAP35	Rho GTPase Activating Protein 35	Protein Coding	1
40	RACGAP1	Rac GTPase Activating Protein 1	Protein Coding	1
41	RHOD	Ras Homolog Family Member D	Protein Coding	1
42	LBR	Lamin B Receptor	Protein Coding	1
43	LMAN1	Lectin, Mannose Binding 1	Protein Coding	1
44	ANKFY1	Ankyrin Repeat And FYVE Domain Containing 1	Protein Coding	1
45	PLXNA1	Plexin A1	Protein Coding	1
46	PLXNB1	Plexin B1	Protein Coding	1
47	ARHGAP17	Rho GTPase Activating Protein 17	Protein Coding	1
48	PAK6	P21 (RAC1) Activated Kinase 6	Protein Coding	1
49	PAK5	P21 (RAC1) Activated Kinase 5	Protein Coding	1
50	VRK2	VRK Serine/Threonine Kinase 2	Protein Coding	1
51	EFHD2	EF-Hand Domain Family Member D2	Protein Coding	1
52	HINT2	Histidine Triad Nucleotide Binding Protein 2	Protein Coding	1
53	STBD1	Starch Binding Domain 1	Protein Coding	1
54	VAPB	VAMP Associated Protein B And C	Protein Coding	1
55	FARP1	FERM, ARH/RhoGEF And Pleckstrin Domain Protein 1	Protein Coding	1
56	BASP1	Brain Abundant Membrane Attached Signal Protein 1	Protein Coding	1
57	SRGAP2	SLIT-ROBO Rho GTPase Activating Protein 2	Protein Coding	1
58	FAM169A	Family With Sequence Similarity 169 Member A	Protein Coding	1
59	SENP1	SUMO Specific Peptidase 1	Protein Coding	1
60	POTEE	POTE Ankyrin Domain Family Member E	Protein Coding	1
61	MYO9B	Myosin IXB	Protein Coding	1
62	RHOF	Ras Homolog Family Member F, Filopodia Associated	Protein Coding	1
63	BAIAP2L1	BAR/IMD Domain Containing Adaptor Protein 2 Like 1	Protein Coding	1
64	ACTB	Actin Beta	Protein Coding	1
65	SOWAHC	Sosondowah Ankyrin Repeat Domain Family Member C	Protein Coding	1
66	BAIAP2L2	BAR/IMD Domain Containing Adaptor Protein 2 Like 2	Protein Coding	1
67	SYDE1	Synapse Defective Rho GTPase Activating Protein 1	Protein Coding	1
68	SNAP23	Synaptosome Associated Protein 23	Protein Coding	1
69	MTMR1	Myotubularin Related Protein 1	Protein Coding	1

Disorders associated with RHOD GTPase cycle SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Martsolf syndrome 1	Enrichment	ARHGAP35, ARHGAP5	3.81
2	Mosaic variegated aneuploidy syndrome 1	Enrichment	BUB1B-PAK6, PAK6	3.81
3	Mosaic variegated aneuploidy syndrome	Enrichment	BUB1B-PAK6, PAK6	3.37
4	Leukodystrophy, demyelinating, adult-onset, autosomal dominant, typical	Enrichment	LMNB1	2.51
5	Baraitser-winter syndrome 1	Enrichment	ACTB	2.51
6	Lipodystrophy, congenital generalized, type 3	Enrichment	CAV1	2.51
7	Deafness, autosomal dominant 1, with or without thrombocytopenia	Enrichment	DIAPH1	2.51
8	Pulmonary hypertension, primary, 3	Enrichment	CAV1	2.51
9	Charcot-marie-tooth disease, axonal, type 2b	Enrichment	RAB7A	2.51
10	Short syndrome	Enrichment	PIK3R1	2.51
11	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	2.51
12	Premature ovarian failure 2a	Enrichment	DIAPH2	2.51
13	Charcot-marie-tooth disease type 2b	Enrichment	RAB7A	2.51
14	Adult onset demyelinating leukodystrophy	Enrichment	LMNB1	2.51
15	Cerebral palsy, spastic quadriplegic, 3	Enrichment	ADD3	2.51
16	Lipodystrophy, familial partial, type 7	Enrichment	CAV1	2.51
17	Auditory neuropathy, autosomal dominant 1	Enrichment	DIAPH3	2.51
18	Becker nevus syndrome	Enrichment	ACTB	2.51
19	Celiac disease 4	Enrichment	MYO9B	2.51
20	Dystonia-deafness syndrome 1	Enrichment	ACTB	2.51
21	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.51
22	Bleeding disorder, platelet-type, 15	Enrichment	ACTN1	2.51
23	Microcephaly 26, primary, autosomal dominant	Enrichment	LMNB1	2.51
24	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.51
25	Seizures, cortical blindness, and microcephaly syndrome	Enrichment	DIAPH1	2.51
26	Diaph1-related sensorineural hearing loss-thrombocytopenia syndrome	Enrichment	DIAPH1	2.51
27	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	2.51
28	Baraitser-winter syndrome	Enrichment	ACTB	2.51
29	Congenital smooth muscle hamartoma	Enrichment	ACTB	2.51
30	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	2.51
31	Buschke-ollendorff syndrome	Enrichment	LEMD3	2.40
32	Greenberg dysplasia	Enrichment	LBR	2.40
33	Pelger-huet anomaly	Enrichment	LBR	2.40
34	Spinal muscular atrophy, late-onset, finkel type	Enrichment	VAPB	2.40
35	Rhizomelic skeletal dysplasia with or without pelger-huet anomaly	Enrichment	LBR	2.40
36	Amyotrophic lateral sclerosis 8	Enrichment	VAPB	2.40
37	Reynolds syndrome	Enrichment	LBR	2.40
38	Melorheostosis with osteopoikilosis	Enrichment	LEMD3	2.40
39	Dworschak-punetha neurodevelopmental syndrome	Enrichment	PLXNA1	2.40
40	Autosomal dominant adult-onset proximal spinal muscular atrophy	Enrichment	VAPB	2.40
41	Congenital dyserythropoietic anemia type iiib	Enrichment	RACGAP1	2.40
42	Anemia, congenital dyserythropoietic, type iiib, autosomal recessive	Enrichment	RACGAP1	2.40
43	Isolated osteopoikilosis	Enrichment	LEMD3	2.40
44	Anemia, hypochromic microcytic, with iron overload 2	Enrichment	STEAP3	2.21
45	Autosomal dominant primary microcephaly	Enrichment	LMNB1	2.21
46	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB	2.21
47	Anemia, congenital dyserythropoietic, type iiia	Enrichment	RACGAP1	2.10
48	Myopathy, x-linked, with postural muscle atrophy	Enrichment	EMD	2.10
49	Osteopoikilosis	Enrichment	LEMD3	2.10
50	Neuromuscular disorder, congenital, with dysmorphic facies	Enrichment	FILIP1	2.10
51	Combined deficiency of factor v and factor viii	Enrichment	LMAN1	2.10
52	12q14 microdeletion syndrome	Enrichment	LEMD3	2.10
53	X-linked emery-dreifuss muscular dystrophy	Enrichment	EMD	2.10
54	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3R1	2.03
55	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	2.03
56	Myopathy, autosomal recessive, with rigid spine and distal joint contractures	Enrichment	TOR1AIP1	2.03
57	Immunodeficiency 14	Enrichment	PIK3R1	2.03
58	Factor v and factor viii, combined deficiency of, 1	Enrichment	LMAN1	1.92
59	Sacral defect with anterior meningocele	Enrichment	VANGL1	1.91
60	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3R2	1.91
61	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	PIK3R2	1.91
62	Aminoacylase 1 deficiency	Enrichment	ACTB	1.91
63	Spastic quadriplegic cerebral palsy	Enrichment	ADD3	1.91
64	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.91
65	Diffuse cutaneous systemic sclerosis	Enrichment	CAV1	1.81
66	Emery-dreifuss muscular dystrophy 1, x-linked	Enrichment	EMD	1.80
67	Emery-dreifuss muscular dystrophy	Enrichment	EMD	1.80
68	Muscular dystrophy, limb-girdle, autosomal recessive 1	Enrichment	TOR1AIP1	1.73
69	Moyamoya disease 1	Enrichment	DIAPH1	1.73
70	Pendred syndrome	Enrichment	DIAPH1	1.73
71	Limited scleroderma	Enrichment	CAV1	1.73
72	Overgrowth syndrome	Enrichment	PIK3R1	1.67
73	Anterior segment dysgenesis 5	Enrichment	ARHGAP35	1.63
74	Autosomal dominant macrothrombocytopenia	Enrichment	ACTN1	1.52
75	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	1.52
76	Heritable pulmonary arterial hypertension	Enrichment	CAV1	1.47
77	Muscular dystrophy, limb-girdle, autosomal recessive 2	Enrichment	TOR1AIP1	1.44
78	Peters-plus syndrome	Enrichment	ARHGAP35	1.41
79	Neural tube defects	Enrichment	VANGL1	1.40
80	Juvenile myelomonocytic leukemia	Enrichment	ARHGAP26	1.33
81	Microcephaly	Enrichment	ACTB, DIAPH1	1.26
82	Centronuclear myopathy	Enrichment	TOR1AIP1	1.20
83	Neuromuscular disease	Enrichment	EMD	1.16
84	Arteriovenous malformations of the brain	Enrichment	LEMD3	1.14
85	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	EMD	1.14
86	Auditory neuropathy	Enrichment	DIAPH1	1.11
87	Jeune thoracic dystrophy	Enrichment	LBR	1.02
88	Asphyxiating thoracic dystrophy	Enrichment	LBR	0.98
89	Cerebral palsy	Enrichment	ADD3	0.94
90	Epilepsy	Enrichment	DIAPH1	0.93
91	Short-rib thoracic dysplasia 1 with or without polydactyly	Enrichment	LBR	0.91
92	Genetic steroid-resistant nephrotic syndrome	Enrichment	ANKFY1	0.90
93	Thrombocytopenia	Enrichment	ACTN1	0.86
94	Myopathy	Enrichment	EMD	0.83
95	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	DIAPH3	0.83
96	Familial isolated dilated cardiomyopathy	Enrichment	TMPO	0.82
97	Myeloma, multiple	Enrichment	PIK3R2	0.80
98	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	VAPB	0.68
99	Rare genetic deafness	Enrichment	DIAPH1	0.66
100	Colorectal cancer	Enrichment	PIK3R1	0.63
101	Dilated cardiomyopathy	Enrichment	EMD	0.56
102	Complex neurodevelopmental disorder	Enrichment	PLXNA1	0.41

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for RHOD GTPase cycle

Member Pathways for RHOD GTPase cycle

Pathways in the RHOD GTPase cycle SuperPath

Associated Genes for RHOD GTPase cycle

Associated Disorders for RHOD GTPase cycle

Disorders associated with RHOD GTPase cycle SuperPath

STRING Interaction Network for RHOD GTPase cycle

Sources for RHOD GTPase cycle