RhoGDI Pathway

No Pathway Network information available for RhoGDI Pathway

Pathways in the RhoGDI Pathway SuperPath

#	Name	Source	Genes
1	RhoGDI Pathway	QIAGEN	ACTR2 ACTR3 ARHGAP1 ARHGAP4 ARHGAP5 ARHGDIA ARHGDIB ARHGDIG ARHGEF1 ARHGEF10 ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF2 ARHGEF3 ARHGEF4 ARHGEF5 ARHGEF6 ARHGEF7 ARHGEF9 BAIAP2 CASP10 CASP3 CDC42 CHN1 CHN2 CLEC18C DIRAS3 EGF EGFR FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT1 FLT4 GZMB JUN KDR MAPK10 MAPK8 MAPK9 MCF2L MET MYH1 MYH10 MYH11 MYH13 MYH14 MYH15 MYH2 MYH3 MYH4 MYH6 MYH7 MYH7B MYH8 MYH9 MYL1 MYL11 MYL2 MYL3 MYL4 MYL5 MYL6 MYL7 MYL9 MYO10 MYO15A MYO18B MYO1A MYO1B MYO1C MYO1D MYO1E MYO1F MYO1G MYO3A MYO3B MYO5A MYO5C MYO6 MYO7A MYO9A MYO9B NET1 NGFR OGFR PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 PARP1 PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PRF1 RHOA RHOB RHOC RHOD RHOG RHOH RND2 RND3 ROCK1 VEGFA VEGFB VEGFC VEGFD WASL (see all 138) (see less)
2	Fc-GammaR-Mediated Phagocytosis in Macrophages	QIAGEN	ACTA1 ACTA2 ACTB ACTG1 ACTG2 ACTR2 ACTR3 ARF6 CDC42 CLEC18C DIRAS3 FCGR1A FCGR2A FCGR3B GSN HCK LYN MYH1 MYH10 MYH11 MYH13 MYH14 MYH15 MYH2 MYH3 MYH4 MYH6 MYH7 MYH7B MYH8 MYH9 MYL1 MYL11 MYL2 MYL3 MYL4 MYL5 MYL6 MYL7 MYL9 MYO10 MYO15A MYO18B MYO1A MYO1B MYO1C MYO1D MYO1E MYO1F MYO1G MYO3A MYO3B MYO5A MYO5C MYO6 MYO7A MYO9A MYO9B PFN1 PFN2 PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PLPP3 PRKCA PTK2B PXN RAC1 RAC2 RAC3 RHOA RHOB RHOC RHOD RHOG RHOH RND2 RND3 SYK VAV1 VAV2 VAV3 VCL (see all 102) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACTR2	Actin Related Protein 2	Protein Coding	2
2	ACTR3	Actin Related Protein 3	Protein Coding	2
3	RHOA	Ras Homolog Family Member A	Protein Coding	2
4	RHOB	Ras Homolog Family Member B	Protein Coding	2
5	RHOC	Ras Homolog Family Member C	Protein Coding	2
6	RHOD	Ras Homolog Family Member D	Protein Coding	2
7	RND3	Rho Family GTPase 3	Protein Coding	2
8	RHOG	Ras Homolog Family Member G	Protein Coding	2
9	RHOH	Ras Homolog Family Member H	Protein Coding	2
10	DIRAS3	DIRAS Family GTPase 3	Protein Coding	2
11	RND2	Rho Family GTPase 2	Protein Coding	2
12	CDC42	Cell Division Cycle 42	Protein Coding	2
13	MYL11	Myosin Light Chain 11	Protein Coding	2
14	MYH15	Myosin Heavy Chain 15	Protein Coding	2
15	CLEC18C	C-Type Lectin Domain Family 18 Member C	Protein Coding	2
16	MYH1	Myosin Heavy Chain 1	Protein Coding	2
17	MYH10	Myosin Heavy Chain 10	Protein Coding	2
18	MYH11	Myosin Heavy Chain 11	Protein Coding	2
19	MYH13	Myosin Heavy Chain 13	Protein Coding	2
20	MYH14	Myosin Heavy Chain 14	Protein Coding	2
21	MYH2	Myosin Heavy Chain 2	Protein Coding	2
22	MYH3	Myosin Heavy Chain 3	Protein Coding	2
23	MYH4	Myosin Heavy Chain 4	Protein Coding	2
24	MYH6	Myosin Heavy Chain 6	Protein Coding	2
25	MYH7	Myosin Heavy Chain 7	Protein Coding	2
26	MYH7B	Myosin Heavy Chain 7B	Protein Coding	2
27	MYH8	Myosin Heavy Chain 8	Protein Coding	2
28	MYH9	Myosin Heavy Chain 9	Protein Coding	2
29	MYL1	Myosin Light Chain 1	Protein Coding	2
30	MYL2	Myosin Light Chain 2	Protein Coding	2
31	MYL3	Myosin Light Chain 3	Protein Coding	2
32	MYL4	Myosin Light Chain 4	Protein Coding	2
33	MYL5	Myosin Light Chain 5	Protein Coding	2
34	MYL6	Myosin Light Chain 6	Protein Coding	2
35	MYL7	Myosin Light Chain 7	Protein Coding	2
36	MYL9	Myosin Light Chain 9	Protein Coding	2
37	MYO10	Myosin X	Protein Coding	2
38	MYO15A	Myosin XVA	Protein Coding	2
39	MYO18B	Myosin XVIIIB	Protein Coding	2
40	MYO1A	Myosin IA	Protein Coding	2
41	MYO1B	Myosin IB	Protein Coding	2
42	MYO1C	Myosin IC	Protein Coding	2
43	MYO1D	Myosin ID	Protein Coding	2
44	MYO1E	Myosin IE	Protein Coding	2
45	MYO1F	Myosin IF	Protein Coding	2
46	MYO1G	Myosin IG	Protein Coding	2
47	MYO3A	Myosin IIIA	Protein Coding	2
48	MYO3B	Myosin IIIB	Protein Coding	2
49	MYO5A	Myosin VA	Protein Coding	2
50	MYO5C	Myosin VC	Protein Coding	2
51	MYO6	Myosin VI	Protein Coding	2
52	MYO7A	Myosin VIIA	Protein Coding	2
53	MYO9A	Myosin IXA	Protein Coding	2
54	MYO9B	Myosin IXB	Protein Coding	2
55	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	2
56	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	2
57	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	2
58	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	2
59	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	2
60	PARP1	Poly(ADP-Ribose) Polymerase 1	Protein Coding	1
61	ARHGAP1	Rho GTPase Activating Protein 1	Protein Coding	1
62	ARHGAP4	Rho GTPase Activating Protein 4	Protein Coding	1
63	ARHGAP5	Rho GTPase Activating Protein 5	Protein Coding	1
64	ARHGDIA	Rho GDP Dissociation Inhibitor Alpha	Protein Coding	1
65	ARHGDIB	Rho GDP Dissociation Inhibitor Beta	Protein Coding	1
66	ARHGDIG	Rho GDP Dissociation Inhibitor Gamma	Protein Coding	1
67	ARHGEF1	Rho Guanine Nucleotide Exchange Factor 1	Protein Coding	1
68	ARHGEF10	Rho Guanine Nucleotide Exchange Factor 10	Protein Coding	1
69	ARHGEF11	Rho Guanine Nucleotide Exchange Factor 11	Protein Coding	1
70	ARHGEF12	Rho Guanine Nucleotide Exchange Factor 12	Protein Coding	1
71	ARHGEF15	Rho Guanine Nucleotide Exchange Factor 15	Protein Coding	1
72	ARHGEF16	Rho Guanine Nucleotide Exchange Factor 16	Protein Coding	1
73	ARHGEF2	Rho/Rac Guanine Nucleotide Exchange Factor 2	Protein Coding	1
74	ARHGEF3	Rho Guanine Nucleotide Exchange Factor 3	Protein Coding	1
75	ARHGEF4	Rho Guanine Nucleotide Exchange Factor 4	Protein Coding	1
76	ARHGEF5	Rho Guanine Nucleotide Exchange Factor 5	Protein Coding	1
77	ARHGEF6	Rac/Cdc42 Guanine Nucleotide Exchange Factor 6	Protein Coding	1
78	ARHGEF7	Rho Guanine Nucleotide Exchange Factor 7	Protein Coding	1
79	ARHGEF9	Cdc42 Guanine Nucleotide Exchange Factor 9	Protein Coding	1
80	BAIAP2	BAR/IMD Domain Containing Adaptor Protein 2	Protein Coding	1
81	CASP10	Caspase 10	Protein Coding	1
82	CASP3	Caspase 3	Protein Coding	1
83	CHN1	Chimerin 1	Protein Coding	1
84	CHN2	Chimerin 2	Protein Coding	1
85	EGF	Epidermal Growth Factor	Protein Coding	1
86	EGFR	Epidermal Growth Factor Receptor	Protein Coding	1
87	FGF1	Fibroblast Growth Factor 1	Protein Coding	1
88	FGF10	Fibroblast Growth Factor 10	Protein Coding	1
89	FGF11	Fibroblast Growth Factor 11	Protein Coding	1
90	FGF12	Fibroblast Growth Factor 12	Protein Coding	1
91	FGF13	Fibroblast Growth Factor 13	Protein Coding	1
92	FGF14	Fibroblast Growth Factor 14	Protein Coding	1
93	FGF16	Fibroblast Growth Factor 16	Protein Coding	1
94	FGF17	Fibroblast Growth Factor 17	Protein Coding	1
95	FGF18	Fibroblast Growth Factor 18	Protein Coding	1
96	FGF19	Fibroblast Growth Factor 19	Protein Coding	1
97	FGF2	Fibroblast Growth Factor 2	Protein Coding	1
98	FGF20	Fibroblast Growth Factor 20	Protein Coding	1
99	FGF21	Fibroblast Growth Factor 21	Protein Coding	1
100	FGF22	Fibroblast Growth Factor 22	Protein Coding	1
101	FGF23	Fibroblast Growth Factor 23	Protein Coding	1
102	FGF3	Fibroblast Growth Factor 3	Protein Coding	1
103	FGF4	Fibroblast Growth Factor 4	Protein Coding	1
104	FGF5	Fibroblast Growth Factor 5	Protein Coding	1
105	FGF6	Fibroblast Growth Factor 6	Protein Coding	1
106	FGF7	Fibroblast Growth Factor 7	Protein Coding	1
107	FGF8	Fibroblast Growth Factor 8	Protein Coding	1
108	FGF9	Fibroblast Growth Factor 9	Protein Coding	1
109	FGFR1	Fibroblast Growth Factor Receptor 1	Protein Coding	1
110	FGFR2	Fibroblast Growth Factor Receptor 2	Protein Coding	1
111	FGFR3	Fibroblast Growth Factor Receptor 3	Protein Coding	1
112	FGFR4	Fibroblast Growth Factor Receptor 4	Protein Coding	1
113	VEGFD	Vascular Endothelial Growth Factor D	Protein Coding	1
114	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	1
115	FLT4	Fms Related Receptor Tyrosine Kinase 4	Protein Coding	1
116	GZMB	Granzyme B	Protein Coding	1
117	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
118	KDR	Kinase Insert Domain Receptor	Protein Coding	1
119	MAPK10	Mitogen-Activated Protein Kinase 10	Protein Coding	1
120	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	1
121	MAPK9	Mitogen-Activated Protein Kinase 9	Protein Coding	1
122	MCF2L	MCF.2 Cell Line Derived Transforming Sequence Like	Protein Coding	1
123	MET	MET Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	1
124	NET1	Neuroepithelial Cell Transforming 1	Protein Coding	1
125	NGFR	Nerve Growth Factor Receptor	Protein Coding	1
126	OGFR	Opioid Growth Factor Receptor	Protein Coding	1
127	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	1
128	PAK2	P21 (RAC1) Activated Kinase 2	Protein Coding	1
129	PAK3	P21 (RAC1) Activated Kinase 3	Protein Coding	1
130	PAK4	P21 (RAC1) Activated Kinase 4	Protein Coding	1
131	PAK6	P21 (RAC1) Activated Kinase 6	Protein Coding	1
132	PAK5	P21 (RAC1) Activated Kinase 5	Protein Coding	1
133	PRF1	Perforin 1	Protein Coding	1
134	ROCK1	Rho Associated Coiled-Coil Containing Protein Kinase 1	Protein Coding	1
135	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1
136	VEGFB	Vascular Endothelial Growth Factor B	Protein Coding	1
137	VEGFC	Vascular Endothelial Growth Factor C	Protein Coding	1
138	WASL	WASP Like Actin Nucleation Promoting Factor	Protein Coding	1
139	ACTA1	Actin Alpha 1, Skeletal Muscle	Protein Coding	1
140	ACTA2	Actin Alpha 2, Smooth Muscle	Protein Coding	1
141	ACTB	Actin Beta	Protein Coding	1
142	ACTG1	Actin Gamma 1	Protein Coding	1
143	ACTG2	Actin Gamma 2, Smooth Muscle	Protein Coding	1
144	ARF6	ARF GTPase 6	Protein Coding	1
145	FCGR1A	Fc Gamma Receptor Ia	Protein Coding	1
146	FCGR2A	Fc Gamma Receptor IIa	Protein Coding	1
147	FCGR3B	Fc Gamma Receptor IIIb	Protein Coding	1
148	GSN	Gelsolin	Protein Coding	1
149	HCK	HCK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
150	LYN	LYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
151	PFN1	Profilin 1	Protein Coding	1
152	PFN2	Profilin 2	Protein Coding	1
153	PIP5K1A	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Alpha	Protein Coding	1
154	PIP5K1B	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Beta	Protein Coding	1
155	PIP5K1C	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Gamma	Protein Coding	1
156	PIP4K2A	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Alpha	Protein Coding	1
157	PIP4K2B	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Beta	Protein Coding	1
158	PIP4K2C	Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Gamma	Protein Coding	1
159	PLCB1	Phospholipase C Beta 1	Protein Coding	1
160	PLCB2	Phospholipase C Beta 2	Protein Coding	1
161	PLCB3	Phospholipase C Beta 3	Protein Coding	1
162	PLCB4	Phospholipase C Beta 4	Protein Coding	1
163	PLCD1	Phospholipase C Delta 1	Protein Coding	1
164	PLCD3	Phospholipase C Delta 3	Protein Coding	1
165	PLCD4	Phospholipase C Delta 4	Protein Coding	1
166	PLCE1	Phospholipase C Epsilon 1	Protein Coding	1
167	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
168	PLCG2	Phospholipase C Gamma 2	Protein Coding	1
169	PLCZ1	Phospholipase C Zeta 1	Protein Coding	1
170	PLPP3	Phospholipid Phosphatase 3	Protein Coding	1
171	PRKCA	Protein Kinase C Alpha	Protein Coding	1
172	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	1
173	PXN	Paxillin	Protein Coding	1
174	RAC1	Rac Family Small GTPase 1	Protein Coding	1
175	RAC2	Rac Family Small GTPase 2	Protein Coding	1
176	RAC3	Rac Family Small GTPase 3	Protein Coding	1
177	SYK	Spleen Associated Tyrosine Kinase	Protein Coding	1
178	VAV1	Vav Guanine Nucleotide Exchange Factor 1	Protein Coding	1
179	VAV2	Vav Guanine Nucleotide Exchange Factor 2	Protein Coding	1
180	VAV3	Vav Guanine Nucleotide Exchange Factor 3	Protein Coding	1
181	VCL	Vinculin	Protein Coding	1

Disorders associated with RhoGDI Pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ACTG1, MYH14, MYH9, MYO1A, MYO1C, MYO6, MYO7A	6.95
2	Non-syndromic genetic deafness	Enrichment	ACTG1, MYH14, MYO15A, MYO3A, MYO6, MYO7A	6.60
3	Nonsyndromic hearing loss	Enrichment	ACTG1, MYH14, MYO15A, MYO3A, MYO6, MYO7A	6.18
4	Lacrimoauriculodentodigital syndrome 1	Enrichment	FGF10, FGFR2, FGFR3	5.99
5	Hemangioma, capillary infantile	Enrichment	FLT4, KDR, MYH9	4.70
6	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	4.25
7	Pfeiffer syndrome	Enrichment	FGFR1, FGFR2	3.99
8	Jackson-weiss syndrome	Enrichment	FGFR1, FGFR2	3.99
9	Congenital myopathy 4a, autosomal dominant	Enrichment	ACTA1, MYH7, MYL2	3.75
10	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	MET, MYH9, MYO15A, MYO3A, MYO6, MYO7A	3.54
11	Hypertrophic cardiomyopathy	Enrichment	MYH7, MYH7B, MYL2, MYL3	3.53
12	Crouzon syndrome	Enrichment	FGFR2, FGFR3	3.51
13	Rare genetic deafness	Enrichment	ACTG1, MYH9, MYO15A, MYO6, MYO7A	3.50
14	Megacystis-microcolon-intestinal hypoperistalsis syndrome 1	Enrichment	ACTG2, MYH11	3.48
15	Dilated cardiomyopathy	Enrichment	ACTA1, MYH6, MYH7, MYL2, VCL	3.47
16	Gliosarcoma	Enrichment	EGFR, FGFR1, FGFR3	3.28
17	Visceral myopathy 1	Enrichment	ACTG2, MYH11	3.26
18	Congenital myopathy 3 with rigid spine	Enrichment	ACTA1, MYH7	3.26
19	Saethre-chotzen syndrome	Enrichment	FGFR2, FGFR3	3.22
20	Giant cell glioblastoma	Enrichment	EGFR, FGFR1, FGFR3	3.20
21	Ear malformation	Enrichment	MYO15A, MYO6, MYO7A	3.13
22	Cardiomyopathy, familial hypertrophic, 1	Enrichment	MYH6, MYH7, MYH7B	3.13
23	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	FGF17, FGF8, FGFR1	3.12
24	Intestinal pseudo-obstruction	Enrichment	ACTG2, MYH11	3.08
25	Hemifacial hyperplasia	Enrichment	FGFR2, FGFR3	3.00
26	Holoprosencephaly	Enrichment	FGF8, FGFR1	3.00
27	Holoprosencephaly 1	Enrichment	FGF8, FGFR1	2.82
28	Lung squamous cell carcinoma	Enrichment	EGFR, FGFR3	2.82
29	Kallmann syndrome	Enrichment	FGF17, FGF8, FGFR1	2.80
30	Familial hypertrophic cardiomyopathy	Enrichment	MYH7, MYL2, MYL3	2.72
31	Colorectal cancer	Enrichment	FGFR2, FGFR3, MET, MYO1B, PIK3R1	2.72
32	Nemaline myopathy	Enrichment	ACTA1, MYO18B	2.62
33	Arthrogryposis, distal, type 1a	Enrichment	MET, MYH3	2.56
34	Lymphoma, non-hodgkin, familial	Enrichment	CASP10, PRF1	2.56
35	Myopathy	Enrichment	ACTA1, MYH2, MYH7	2.48
36	Distal arthrogryposis	Enrichment	ACTA1, MYH3, MYL11	2.42
37	Sensorineural hearing loss	Enrichment	MYO15A, MYO3A, MYO7A	2.25
38	Cardiomyopathy, dilated, 1e	Enrichment	MYH7, MYL2	2.15
39	Familial isolated dilated cardiomyopathy	Enrichment	MYH6, MYH7, VCL	2.13
40	Contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a	Enrichment	MYH3	2.12
41	Baraitser-winter syndrome 1	Enrichment	ACTB	2.12
42	Deafness, autosomal recessive 2	Enrichment	MYO7A	2.12
43	Deafness, autosomal dominant 17	Enrichment	MYH9	2.12
44	Deafness, autosomal dominant 48	Enrichment	MYO1A	2.12
45	Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis	Enrichment	RAC2	2.12
46	Cardiomyopathy, familial hypertrophic, 8	Enrichment	MYL3	2.12
47	Congenital myopathy 2a, typical, autosomal dominant	Enrichment	ACTA1	2.12
48	Amyloidosis, finnish type	Enrichment	GSN	2.12
49	Deafness, autosomal dominant 22	Enrichment	MYO6	2.12
50	Nail disorder, nonsyndromic congenital, 3	Enrichment	PLCD1	2.12
51	Amyotrophic lateral sclerosis 18	Enrichment	PFN1	2.12
52	Myopathy, scapulohumeroperoneal	Enrichment	ACTA1	2.12
53	Cardiomyopathy, dilated, 1ee	Enrichment	MYH6	2.12
54	Sick sinus syndrome 3	Enrichment	MYH6	2.12
55	Griscelli syndrome, type 1	Enrichment	MYO5A	2.12
56	Elejalde neuroectodermal melanolysosomal syndrome	Enrichment	MYO5A	2.12
57	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	2.12
58	Megacystis-microcolon-intestinal hypoperistalsis syndrome 5	Enrichment	ACTG2	2.12
59	Spondylometaphyseal dysplasia with corneal dystrophy	Enrichment	PLCB3	2.12
60	Immunodeficiency 82 with systemic inflammation	Enrichment	SYK	2.12
61	Deafness, autosomal dominant 4a	Enrichment	MYH14	2.12
62	Neurodevelopmental disorder with structural brain anomalies and dysmorphic facies	Enrichment	RAC3	2.12
63	Short syndrome	Enrichment	PIK3R1	2.12
64	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	2.12
65	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.12
66	Deafness, autosomal recessive 37	Enrichment	MYO6	2.12
67	Auriculocondylar syndrome 2a	Enrichment	PLCB4	2.12
68	Diarrhea 15, congenital	Enrichment	MYO1A	2.12
69	Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia	Enrichment	RAC2	2.12
70	Atrial fibrillation, familial, 18	Enrichment	MYL4	2.12
71	Deafness, autosomal dominant 11	Enrichment	MYO7A	2.12
72	Cardiomyopathy, dilated, 1w	Enrichment	VCL	2.12
73	Deafness, autosomal recessive 30	Enrichment	MYO3A	2.12
74	Becker nevus syndrome	Enrichment	ACTB	2.12
75	Celiac disease 4	Enrichment	MYO9B	2.12
76	Dystonia-deafness syndrome 1	Enrichment	ACTB	2.12
77	Visceral neuropathy, familial, 3, autosomal dominant	Enrichment	ACTG2	2.12
78	Cardiomyopathy, familial hypertrophic, 14	Enrichment	MYH6	2.12
79	Cardiomyopathy, familial hypertrophic, 15	Enrichment	VCL	2.12
80	Congenital myopathy 2b, severe infantile, autosomal recessive	Enrichment	ACTA1	2.12
81	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.12
82	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	2.12
83	Peripheral neuropathy, myopathy, hoarseness, and hearing loss	Enrichment	MYH14	2.12
84	Autosomal dominant familial visceral neuropathy	Enrichment	ACTG2	2.12
85	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.12
86	Focal segmental glomerulosclerosis 6	Enrichment	MYO1E	2.12
87	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	2.12
88	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	2.12
89	Takenouchi-kosaki syndrome	Enrichment	CDC42	2.12
90	Congenital myopathy 2c, severe infantile, autosomal dominant	Enrichment	ACTA1	2.12
91	Autoinflammatory disease, systemic, with vasculitis	Enrichment	LYN	2.12
92	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	2.12
93	Deafness, autosomal dominant 90	Enrichment	MYO3A	2.12
94	Myasthenic syndrome, congenital, 24, presynaptic	Enrichment	MYO9A	2.12
95	Congenital myopathy 14	Enrichment	MYL1	2.12
96	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	2.12
97	Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia	Enrichment	RAC2	2.12
98	Immunodeficiency 129	Enrichment	RHOH	2.12
99	Auriculocondylar syndrome 2b	Enrichment	PLCB4	2.12
100	Baraitser-winter syndrome	Enrichment	ACTB	2.12
101	Autoinflammation with pulmonary and cutaneous vasculitis	Enrichment	HCK	2.12
102	Usher syndrome type 1b	Enrichment	MYO7A	2.12
103	T-cell immunodeficiency with epidermodysplasia verruciformis	Enrichment	RHOH	2.12
104	Colitis	Enrichment	SYK	2.12
105	Klippel-feil syndrome	Enrichment	MYO18B	2.12
106	Autosomal dominant nonsyndromic hearing loss 17	Enrichment	MYH9	2.12
107	Progressive sensorineural hearing loss-hypertrophic cardiomyopathy syndrome	Enrichment	MYO6	2.12
108	Neonatal alloimmune neutropenia	Enrichment	FCGR3B	2.12
109	Zebra body myopathy	Enrichment	ACTA1	2.12
110	Infantile lad-like disease due to rac2 deficiency	Enrichment	RAC2	2.12
111	Congenital smooth muscle hamartoma	Enrichment	ACTB	2.12
112	Reticular dysgenesis-like severe combined immunodeficiency	Enrichment	RAC2	2.12
113	Nocarh syndrome	Enrichment	CDC42	2.12
114	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	2.12
115	Autosomal dominant nonsyndromic hearing loss 22	Enrichment	MYO6	2.12
116	Actin-accumulation myopathy	Enrichment	ACTA1	2.12
117	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.12
118	Myopathic intestinal pseudoobstruction	Enrichment	ACTG2	2.12
119	Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome	Enrichment	RAC2	2.12
120	Actg2 visceral myopathy	Enrichment	ACTG2	2.12
121	Neuromuscular disease	Enrichment	ACTA1, MYH7	2.10
122	Lung cancer susceptibility 3	Enrichment	EGFR, FGF10	2.06
123	Congenital myopathy	Enrichment	ACTA1, MYH7	2.06
124	Hypochondroplasia	Enrichment	FGFR3	1.99
125	Beare-stevenson cutis gyrata syndrome	Enrichment	FGFR2	1.99
126	Osteoglophonic dysplasia	Enrichment	FGFR1	1.99
127	Thanatophoric dysplasia, type i	Enrichment	FGFR3	1.99
128	Trigonocephaly 1	Enrichment	FGFR1	1.99
129	Spinocerebellar ataxia 27a	Enrichment	FGF14	1.99
130	Muenke syndrome	Enrichment	FGFR3	1.99
131	Intellectual developmental disorder, x-linked 30	Enrichment	PAK3	1.99
132	Developmental and epileptic encephalopathy 8	Enrichment	ARHGEF9	1.99
133	Hemophagocytic lymphohistiocytosis, familial, 2	Enrichment	PRF1	1.99
134	Hypomagnesemia 4, renal	Enrichment	EGF	1.99
135	Scaphocephaly, maxillary retrusion, and impaired intellectual development	Enrichment	FGFR2	1.99
136	Apert syndrome	Enrichment	FGFR2	1.99
137	Thanatophoric dysplasia, type ii	Enrichment	FGFR3	1.99
138	Nephrotic syndrome, type 8	Enrichment	ARHGDIA	1.99
139	Hypogonadotropic hypogonadism 20 with or without anosmia	Enrichment	FGF17	1.99
140	Camptodactyly, tall stature, and hearing loss syndrome	Enrichment	FGFR3	1.99
141	Aplasia of lacrimal and salivary glands	Enrichment	FGF10	1.99
142	Bent bone dysplasia syndrome 1	Enrichment	FGFR2	1.99
143	Immunodeficiency 62	Enrichment	ARHGEF1	1.99
144	Neurodevelopmental disorder with midbrain and hindbrain malformations	Enrichment	ARHGEF2	1.99
145	Intellectual developmental disorder, x-linked 110	Enrichment	FGF13	1.99
146	Spinocerebellar ataxia 27b, late-onset	Enrichment	FGF14	1.99
147	Knobloch syndrome 2	Enrichment	PAK2	1.99
148	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	1.99
149	Hereditary lymphedema id	Enrichment	VEGFC	1.99
150	Osteofibrous dysplasia	Enrichment	MET	1.99
151	Intellectual developmental disorder, x-linked 46	Enrichment	ARHGEF6	1.99
152	Developmental and epileptic encephalopathy 90	Enrichment	FGF13	1.99
153	Metacarpal 4-5 fusion	Enrichment	FGF16	1.99
154	Lymphatic malformation 4	Enrichment	VEGFC	1.99
155	Lacrimoauriculodentodigital syndrome 3	Enrichment	FGF10	1.99
156	Familial isolated trichomegaly	Enrichment	FGF5	1.99
157	Slowed nerve conduction velocity, autosomal dominant	Enrichment	ARHGEF10	1.99
158	Deafness, autosomal recessive 97	Enrichment	MET	1.99
159	Microvascular complications of diabetes 1	Enrichment	VEGFA	1.99
160	Crouzon syndrome with acanthosis nigricans	Enrichment	FGFR3	1.99
161	Autoimmune lymphoproliferative syndrome, type iia	Enrichment	CASP10	1.99
162	Autism 9	Enrichment	MET	1.99
163	Multiple synostoses syndrome 3	Enrichment	FGF9	1.99
164	Hypogonadotropic hypogonadism 6 with or without anosmia	Enrichment	FGF8	1.99
165	Brain small vessel disease 5 with osteoporosis	Enrichment	ARHGEF15	1.99
166	Achondroplasia, severe, with developmental delay and acanthosis nigricans	Enrichment	FGFR3	1.99
167	Tumoral calcinosis, hyperphosphatemic, familial, 2	Enrichment	FGF23	1.99
168	Hartsfield syndrome	Enrichment	FGFR1	1.99
169	Congenital heart defects, multiple types, 7	Enrichment	FLT4	1.99
170	Renal hypodysplasia/aplasia 2	Enrichment	FGF20	1.99
171	Developmental and epileptic encephalopathy 47	Enrichment	FGF12	1.99
172	Tufted angioma of skin	Enrichment	KDR	1.99
173	Arthrogryposis, distal, type 11	Enrichment	MET	1.99
174	Lacrimoauriculodentodigital syndrome 2	Enrichment	FGFR3	1.99
175	Short-rib thoracic dysplasia 22 without polydactyly	Enrichment	FGF4	1.99
176	Spinocerebellar ataxia type 27b	Enrichment	FGF14	1.99
177	Fgfr3-related chondrodysplasia	Enrichment	FGFR3	1.99
178	Congenital primary lymphedema of gordon	Enrichment	VEGFC	1.99
179	Camptodactyly-tall stature-scoliosis-hearing loss syndrome	Enrichment	FGFR3	1.99
180	Fatal post-viral neurodegenerative disorder	Enrichment	PRF1	1.99
181	Hartsfield-bixler-demyer syndrome	Enrichment	FGFR1	1.99
182	Egf-related primary hypomagnesemia with intellectual disability	Enrichment	EGF	1.99
183	Non-syndromic unicoronal craniosynostosis	Enrichment	FGFR2	1.99
184	Interstitial lung disease specific to childhood	Enrichment	FGF10	1.99
185	Microform holoprosencephaly	Enrichment	FGF8, FGFR1	1.95
186	Lobar holoprosencephaly	Enrichment	FGF8, FGFR1	1.95
187	Deafness, autosomal recessive	Enrichment	MYH9, MYO15A, MYO7A	1.93
188	Autosomal recessive nonsyndromic deafness	Enrichment	MYH9, MYO15A, MYO7A	1.91
189	Semilobar holoprosencephaly	Enrichment	FGF8, FGFR1	1.85
190	Aortic aneurysm, familial thoracic 4	Enrichment	MYH11	1.82
191	Arthrogryposis, distal, type 2a	Enrichment	MYH3	1.82
192	Ebstein anomaly	Enrichment	MYH7	1.82
193	Cataract 35	Enrichment	MYH9	1.82
194	Lethal congenital contracture syndrome 3	Enrichment	PIP5K1C	1.82
195	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	1.82
196	Deafness, autosomal dominant 30	Enrichment	MYO3A	1.82
197	Aortic aneurysm, familial thoracic 2	Enrichment	ACTA2	1.82
198	Griscelli syndrome, type 3	Enrichment	MYO5A	1.82
199	Arthrogryposis, distal, type 7	Enrichment	MYH8	1.82
200	Deafness, autosomal dominant 20	Enrichment	ACTG1	1.82
201	Smooth muscle dysfunction syndrome	Enrichment	ACTA2	1.82
202	Neutrophilia, hereditary	Enrichment	PIP4K2B	1.82
203	Aortic aneurysm, familial thoracic 6	Enrichment	ACTA2	1.82
204	Baraitser-winter syndrome 2	Enrichment	ACTG1	1.82
205	Moyamoya disease 5	Enrichment	ACTA2	1.82
206	Spermatogenic failure 17	Enrichment	PLCZ1	1.82
207	Neutropenia, severe congenital, 7, autosomal recessive	Enrichment	PIP4K2B	1.82
208	Arthrogryposis, distal, type 2b3	Enrichment	MYH3	1.82
209	Megacystis-microcolon-intestinal hypoperistalsis syndrome 2	Enrichment	MYH11	1.82
210	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	1.82
211	Atrial septal defect 3	Enrichment	MYH6	1.82
212	Cardiomyopathy, familial hypertrophic, 10	Enrichment	MYL2	1.82
213	Severe congenital neutropenia 7	Enrichment	PIP4K2B	1.82
214	Ocular melanoma	Enrichment	PLCB4	1.82
215	Intellectual developmental disorder, autosomal dominant 60, with seizures	Enrichment	PIP5K1A	1.82
216	Hereditary inclusion body myopathy-joint contractures-ophthalmoplegia syndrome	Enrichment	MYH2	1.82
217	Pseudosarcomatous fibromatosis	Enrichment	MYH9	1.82
218	Immune system disease	Enrichment	CDC42	1.82
219	Visceral myopathy 2	Enrichment	MYH11	1.82
220	Myopathy, myofibrillar, 12, infantile-onset, with cardiomyopathy	Enrichment	MYL2	1.82
221	B-lymphoblastic leukemia/lymphoma with hyperdiploidy	Enrichment	PIP4K2A	1.82
222	Klippel-feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism	Enrichment	MYO18B	1.82
223	Arthrogryposis, distal, type 1c	Enrichment	MYL11	1.82
224	Megacystis-microcolon-intestinal hypoperistalsis syndrome 4	Enrichment	MYL9	1.82
225	Klippel-feil anomaly-myopathy-facial dysmorphism syndrome	Enrichment	MYO18B	1.82
226	Arthritis	Enrichment	SYK	1.82
227	Childhood-onset autosomal recessive myopathy with external ophthalmoplegia	Enrichment	MYH2	1.82
228	Intestinal obstruction	Enrichment	ACTG2	1.82
229	Carney complex - trismus - pseudocamptodactyly syndrome	Enrichment	MYH8	1.82
230	Craniosynostosis	Enrichment	FGFR2, FGFR3	1.76
231	Lymphatic malformation 1	Enrichment	FLT4	1.69
232	Otodental dysplasia	Enrichment	FGF3	1.69
233	Trichomegaly	Enrichment	FGF5	1.69
234	Intracranial hypertension, idiopathic	Enrichment	FLT4	1.69
235	Pulmonary hypoplasia, primary	Enrichment	FGF10	1.69
236	Cervical cancer	Enrichment	FGFR3	1.69
237	Aural atresia, congenital	Enrichment	FGFR2	1.69
238	Keratosis, seborrheic	Enrichment	FGFR3	1.69
239	Deafness, congenital, with inner ear agenesis, microtia, and microdontia	Enrichment	FGF3	1.69
240	Encephalocraniocutaneous lipomatosis	Enrichment	FGFR1	1.69
241	Duane retraction syndrome 2	Enrichment	CHN1	1.69
242	Angioma, tufted	Enrichment	KDR	1.69
243	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis	Enrichment	FGFR2	1.69
244	Childhood hepatocellular carcinoma	Enrichment	MET	1.69
245	Split hand-foot malformation	Enrichment	FGFR2	1.69
246	Rosette-forming glioneuronal tumor	Enrichment	FGFR1	1.69
247	Papillary renal cell carcinoma	Enrichment	MET	1.69
248	Cervix carcinoma	Enrichment	FGFR3	1.69
249	Hereditary lymphedema i	Enrichment	FLT4	1.69
250	Interfrontal craniofaciosynostosis	Enrichment	FGFR1	1.69
251	Autosomal dominant nonsyndromic deafness	Enrichment	FGFR2	1.69
252	Oculootodental syndrome	Enrichment	FGF3	1.69
253	Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss	Enrichment	MYH9	1.65
254	Klippel-feil syndrome 1, autosomal dominant	Enrichment	MYO18B	1.65
255	Deafness, autosomal recessive 3	Enrichment	MYO15A	1.65
256	Cardiomyopathy, dilated, 1c, with or without left ventricular noncompaction	Enrichment	MYH7B	1.65
257	Spondylocarpotarsal synostosis syndrome	Enrichment	MYH3	1.65
258	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3R1	1.65
259	Nephrotic syndrome, type 3	Enrichment	PLCE1	1.65
260	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	1.65
261	Microcephaly, progressive, with seizures and cerebral and cerebellar atrophy	Enrichment	MYH15	1.65
262	Immunodeficiency 14	Enrichment	PIK3R1	1.65
263	Qualitative or quantitative defects of beta-myosin heavy chain	Enrichment	MYH7	1.65
264	Idiopathic camptocormia	Enrichment	MYH7	1.65
265	Congenital diarrhea	Enrichment	MYO1A	1.65
266	Tricuspid valve insufficiency	Enrichment	MYH11	1.65
267	Genetic steroid-resistant nephrotic syndrome	Enrichment	MYO1E, PLCE1	1.57
268	Left ventricular noncompaction	Enrichment	MYH7, MYH7B	1.55
269	Tetralogy of fallot	Enrichment	FLT4, KDR	1.55
270	Myopathy, distal, 1	Enrichment	MYH7	1.53
271	Klippel-feil syndrome 2, autosomal recessive	Enrichment	MYO18B	1.53
272	Nemaline myopathy 2	Enrichment	ACTA1	1.53
273	Congenital myopathy 7b, myosin storage, autosomal recessive	Enrichment	MYH7	1.53
274	Autoimmune lymphoproliferative syndrome	Enrichment	ACTA2	1.53
275	Auriculocondylar syndrome 1	Enrichment	PLCB4	1.53
276	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3R2	1.53
277	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	PIK3R2	1.53
278	Carney complex variant	Enrichment	MYH8	1.53
279	Congenital myopathy 7a, myosin storage, autosomal dominant	Enrichment	MYH7	1.53
280	Congenital myopathy 6 with ophthalmoplegia	Enrichment	MYH2	1.53
281	Aminoacylase 1 deficiency	Enrichment	ACTB	1.53
282	Developmental and epileptic encephalopathy 12	Enrichment	PLCB1	1.53
283	Contractures, pterygia, and spondylocarpotarsal fusion syndrome 1b	Enrichment	MYH3	1.53
284	Hyaline body myopathy	Enrichment	MYH7	1.53
285	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CDC42	1.53
286	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	MYH11	1.53
287	Mitral valve insufficiency	Enrichment	MYH11	1.53
288	Intermediate nemaline myopathy	Enrichment	ACTA1	1.53
289	Familial sick sinus syndrome	Enrichment	MYH6	1.53
290	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.53
291	Achondroplasia	Enrichment	FGFR3	1.52
292	Hypogonadotropic hypogonadism 2 with or without anosmia	Enrichment	FGFR1	1.52
293	Larsen syndrome	Enrichment	FGFR3	1.52
294	Tumoral calcinosis, hyperphosphatemic, familial, 1	Enrichment	FGF23	1.52
295	Hypophosphatemic rickets, autosomal dominant	Enrichment	FGF23	1.52
296	Chromosome 8p11 myeloproliferative syndrome	Enrichment	FGFR1	1.52
297	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	1.52
298	Hamartoma	Enrichment	FGFR3	1.52
299	Testicular germ cell cancer	Enrichment	FGFR3	1.52
300	Duane retraction syndrome	Enrichment	CHN1	1.52
301	Spermatocytoma	Enrichment	FGFR3	1.52
302	Neonatal inflammatory skin and bowel disease	Enrichment	EGFR	1.52
303	Renal cell carcinoma	Enrichment	MET	1.52
304	Testicular cancer	Enrichment	FGFR3	1.52
305	Systemic lupus erythematosus	Enrichment	FCGR2A, FCGR3B	1.46
306	Bladder cancer	Enrichment	EGFR, FGFR3	1.46
307	Arthrogryposis, distal, type 2b1	Enrichment	MYH3	1.43
308	Deafness, autosomal recessive 9	Enrichment	MYO15A	1.43
309	Deafness, autosomal recessive 63	Enrichment	MYH9	1.43
310	Congenital ptosis	Enrichment	MYH10	1.43
311	Otof-related hearing loss	Enrichment	MYO15A	1.43
312	Coloboma of choroid and retina	Enrichment	ACTG1	1.43
313	Severe congenital nemaline myopathy	Enrichment	ACTA1	1.43
314	Multiple synostoses syndrome	Enrichment	FGF9	1.40
315	Knobloch syndrome	Enrichment	PAK2	1.40
316	Non-syndromic bicoronal craniosynostosis	Enrichment	FGFR3	1.40
317	Glioma	Enrichment	FGFR2	1.40
318	Nephrotic syndrome	Enrichment	MYO1E, PLCE1	1.38
319	Lung cancer	Enrichment	EGFR, MET	1.38
320	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	ACTA2, MYH11	1.36
321	Melanoma, uveal	Enrichment	PLCB4	1.35
322	Hemihyperplasia, isolated	Enrichment	RHOA	1.35
323	Moyamoya disease 1	Enrichment	ACTA2	1.35
324	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	MYO6	1.35
325	Inherited arrhythmogenic cardiomyopathy	Enrichment	MYH7	1.35
326	Typical nemaline myopathy	Enrichment	ACTA1	1.35
327	Moebius syndrome	Enrichment	CHN1	1.30
328	Martsolf syndrome 1	Enrichment	ARHGAP5	1.30
329	Hemophagocytic lymphohistiocytosis, familial, 1	Enrichment	PRF1	1.30
330	Knobloch syndrome 1	Enrichment	PAK2	1.30
331	Mosaic variegated aneuploidy syndrome 1	Enrichment	PAK6	1.30
332	Robinow syndrome, autosomal dominant 2	Enrichment	CHN1	1.30
333	Pre-eclampsia	Enrichment	FLT1	1.30
334	Primary hypereosinophilic syndrome	Enrichment	FGFR1	1.30
335	Idiopathic aplastic anemia	Enrichment	PRF1	1.30
336	Meniere disease	Enrichment	MYO7A	1.29
337	Childhood-onset nemaline myopathy	Enrichment	ACTA1	1.29
338	Overgrowth syndrome	Enrichment	PIK3R1	1.29
339	Familial isolated restrictive cardiomyopathy	Enrichment	MYL2	1.29
340	Myocarditis	Enrichment	MYH7	1.23
341	Hypoplastic left heart syndrome	Enrichment	MYH6	1.23
342	Cowden syndrome 1	Enrichment	EGFR	1.23
343	Split-hand/foot malformation 1	Enrichment	FGFR2	1.23
344	Testicular germ cell tumor	Enrichment	FGFR3	1.23
345	46,xy disorder of sex development	Enrichment	FGFR3	1.23
346	Cardiomyopathy, familial hypertrophic, 4	Enrichment	MYH7	1.18
347	Nephrotic syndrome, type 1	Enrichment	PLCE1	1.18
348	Developmental and epileptic encephalopathy 14	Enrichment	PLCB1	1.18
349	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	1.18
350	Familial isolated arrhythmogenic right ventricular dysplasia	Enrichment	MYH7	1.18
351	Familial thoracic aortic aneurysm and dissection	Enrichment	MYH11	1.18
352	Nevus, epidermal	Enrichment	FGFR3	1.16
353	Squamous cell carcinoma, head and neck	Enrichment	EGFR	1.16
354	Renal cell carcinoma, papillary, 1	Enrichment	MET	1.16
355	Pilomyxoid astrocytoma	Enrichment	FGFR1	1.16
356	Hypophosphatemic rickets	Enrichment	FGF23	1.16
357	Gastric cancer	Enrichment	CASP10, FGFR2	1.15
358	Cat eye syndrome	Enrichment	ACTG1	1.14
359	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	1.14
360	Lennox-gastaut syndrome	Enrichment	MAPK10	1.10
361	Mosaic variegated aneuploidy syndrome	Enrichment	PAK6	1.10
362	Immune deficiency disease	Enrichment	SYK	1.10
363	Usher syndrome type 2	Enrichment	MYO7A	1.10
364	Presynaptic congenital myasthenic syndromes	Enrichment	MYO9A	1.10
365	Restrictive cardiomyopathy	Enrichment	MYH7	1.06
366	Orofacial cleft 1	Enrichment	FGF10	1.06
367	Adult hepatocellular carcinoma	Enrichment	EGF	1.06
368	Hypogonadotropic hypogonadism	Enrichment	FGFR1	1.06
369	Renal agenesis, bilateral	Enrichment	FGF20	1.06
370	Microphthalmia/coloboma 12	Enrichment	MYH10	1.03
371	Meier-gorlin syndrome 1	Enrichment	FGFR2	1.01
372	Aplastic anemia	Enrichment	PRF1	1.01
373	Primary bone dysplasia	Enrichment	FGFR3	1.01
374	Hypertelorism	Enrichment	FGFR2, MYH10	1.01
375	Aortic aneurysm, familial thoracic 1	Enrichment	MYH11	1.00
376	Heart disease	Enrichment	MYL2	1.00
377	Osteochondrodysplasia	Enrichment	FGFR3	0.97
378	Lung non-small cell carcinoma	Enrichment	EGFR	0.97
379	Coloboma of macula	Enrichment	MYH10	0.97
380	Usher syndrome, type i	Enrichment	MYO7A	0.97
381	Myopia	Enrichment	MYH11	0.97
382	Myeloma, multiple	Enrichment	FGFR3, PIK3R2	0.95
383	Wolff-parkinson-white syndrome	Enrichment	MYH7	0.94
384	Hypertension	Enrichment	MYH9	0.94
385	Septooptic dysplasia	Enrichment	FGFR1	0.94
386	Renal hypodysplasia/aplasia 3	Enrichment	FGFR3	0.94
387	Lip and oral cavity carcinoma	Enrichment	EGFR	0.94
388	Heart, malformation of	Enrichment	MYH6	0.90
389	Patent foramen ovale	Enrichment	MYH6	0.90
390	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	FGFR1	0.87
391	Generalized epilepsy with febrile seizures plus	Enrichment	FGF13	0.87
392	Focal segmental glomerulosclerosis	Enrichment	PLCE1	0.85
393	Renal cell carcinoma, nonpapillary	Enrichment	MET	0.85
394	Hydrocephalus	Enrichment	FGFR2	0.85
395	Septopreoptic holoprosencephaly	Enrichment	FGF8	0.85
396	Midline interhemispheric variant of holoprosencephaly	Enrichment	FGF8	0.85
397	Lissencephaly	Enrichment	ACTG1	0.83
398	Centronuclear myopathy	Enrichment	ACTA1	0.83
399	Malaria	Enrichment	FCGR2A	0.80
400	Alobar holoprosencephaly	Enrichment	FGF8	0.80
401	Familial atrial fibrillation	Enrichment	MYL4	0.78
402	Arteriovenous malformations of the brain	Enrichment	EGFR	0.75
403	Hydrops fetalis, nonimmune	Enrichment	ACTA1	0.75
404	Auditory neuropathy	Enrichment	MYO7A	0.75
405	Endometrial cancer	Enrichment	FGFR2	0.71
406	Hepatoblastoma	Enrichment	FGFR3	0.71
407	Hepatocellular carcinoma	Enrichment	MET	0.70
408	Tooth agenesis	Enrichment	FGFR1	0.70
409	Long qt syndrome	Enrichment	MYH6	0.68
410	Non-immune hydrops fetalis	Enrichment	ACTA1	0.68
411	Cystic fibrosis	Enrichment	FCGR2A	0.67
412	Connective tissue disease	Enrichment	ACTA2	0.67
413	Autoinflammatory disease	Enrichment	PRF1	0.66
414	Usher syndrome	Enrichment	MYO7A	0.66
415	Cakut	Enrichment	ACTG1	0.64
416	Dystonia	Enrichment	MYO5A	0.63
417	Microcephaly	Enrichment	ACTB, ACTG1	0.63
418	Complex neurodevelopmental disorder	Enrichment	MYH10, RAC3	0.62
419	Fetal akinesia deformation sequence 1	Enrichment	ACTA1	0.61
420	Severe covid-19	Enrichment	CASP10	0.59
421	Benign epilepsy with centrotemporal spikes	Enrichment	PLCB1	0.57
422	Ovarian cancer	Enrichment	EGFR, MET	0.56
423	Centralopathic epilepsy	Enrichment	PLCB1	0.56
424	West syndrome	Enrichment	PLCB1	0.55
425	Thrombocytopenia	Enrichment	MYH9	0.52
426	Non-syndromic x-linked intellectual disability	Enrichment	ARHGEF6	0.51
427	Developmental and epileptic encephalopathy	Enrichment	ARHGEF15	0.51
428	Body mass index quantitative trait locus 11	Enrichment	MYH9	0.50
429	Hereditary breast ovarian cancer syndrome	Enrichment	MYO7A	0.47
430	Charcot-marie-tooth disease	Enrichment	ARHGEF10	0.46
431	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	PFN1	0.45
432	Inherited cancer-predisposing syndrome	Enrichment	EGFR, MET	0.41
433	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	FGF8	0.36
434	Undetermined early-onset epileptic encephalopathy	Enrichment	FGF12	0.36
435	Primary ovarian insufficiency	Enrichment	KDR	0.34
436	Breast cancer	Enrichment	JUN	0.27
437	Congenital nervous system abnormality	Enrichment	FGFR3	0.18
438	Nervous system disease	Enrichment	FGFR3	0.18
439	Retinitis pigmentosa	Enrichment	MYO7A	0.10
440	Hereditary retinal dystrophy	Enrichment	MYO7A	0.05
441	Fundus dystrophy	Enrichment	MYO7A	0.05

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

RhoGDI Pathway

Pathway Network for RhoGDI Pathway

Member Pathways for RhoGDI Pathway

Pathways in the RhoGDI Pathway SuperPath

Associated Genes for RhoGDI Pathway

Associated Disorders for RhoGDI Pathway

Disorders associated with RhoGDI Pathway SuperPath

STRING Interaction Network for RhoGDI Pathway

Sources for RhoGDI Pathway