Riboflavin and CoQ disorders

No Pathway Network information available for Riboflavin and CoQ disorders

Pathways in the Riboflavin and CoQ disorders SuperPath

#	Name	Source	Genes
1	Riboflavin and CoQ disorders	WikiPathways	APTX COQ2 COQ6 COQ7 COQ8A COQ9 ETFA ETFDH FLAD1 PDSS1 PDSS2 RFK SLC52A1 SLC52A2 (see all 14) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SLC52A1	Solute Carrier Family 52 Member 1	Protein Coding	1
2	SLC52A2	Solute Carrier Family 52 Member 2	Protein Coding	1
3	COQ8A	Coenzyme Q8A	Protein Coding	1
4	APTX	Aprataxin	Protein Coding	1
5	COQ7	Coenzyme Q7, Hydroxylase	Protein Coding	1
6	PDSS2	Decaprenyl Diphosphate Synthase Subunit 2	Protein Coding	1
7	COQ2	Coenzyme Q2, Polyprenyltransferase	Protein Coding	1
8	COQ9	Coenzyme Q9	Protein Coding	1
9	COQ6	Coenzyme Q6, Monooxygenase	Protein Coding	1
10	PDSS1	Decaprenyl Diphosphate Synthase Subunit 1	Protein Coding	1
11	RFK	Riboflavin Kinase	Protein Coding	1
12	FLAD1	Flavin Adenine Dinucleotide Synthetase 1	Protein Coding	1
13	ETFA	Electron Transfer Flavoprotein Subunit Alpha	Protein Coding	1
14	ETFDH	Electron Transfer Flavoprotein Dehydrogenase	Protein Coding	1

Disorders associated with Riboflavin and CoQ disorders SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Multiple acyl-coa dehydrogenase deficiency	Enrichment	ETFA, ETFDH, FLAD1	8.45
2	Multiple acyl-coa dehydrogenase deficiency, severe neonatal type	Enrichment	ETFA, ETFDH, FLAD1	8.06
3	Multiple acyl-coa dehydrogenase deficiency, mild type	Enrichment	ETFA, ETFDH, FLAD1	8.06
4	Coenzyme q10 deficiency, primary, 1	Enrichment	COQ2, COQ8A	5.53
5	Coenzyme q10 deficiency, primary, 5	Enrichment	COQ7, COQ9	5.53
6	Nephrotic syndrome	Enrichment	COQ2, PDSS2	3.06
7	Lipid storage myopathy due to flavin adenine dinucleotide synthetase deficiency	Enrichment	FLAD1	2.99
8	Coenzyme q10 deficiency, primary, 4	Enrichment	COQ8A	2.99
9	Coenzyme q10 deficiency, primary, 2	Enrichment	PDSS1	2.99
10	Riboflavin deficiency	Enrichment	SLC52A1	2.99
11	Coenzyme q10 deficiency, primary, 3	Enrichment	PDSS2	2.99
12	Maternal riboflavin deficiency	Enrichment	SLC52A1	2.99
13	Multiple system atrophy, parkinsonian type	Enrichment	COQ2	2.99
14	Multiple system atrophy 1	Enrichment	COQ2	2.69
15	Brown-vialetto-van laere syndrome 1	Enrichment	SLC52A2	2.69
16	Coenzyme q10 deficiency, primary, 6	Enrichment	COQ6	2.69
17	Glutaric aciduria iii	Enrichment	ETFA	2.69
18	Multiple system atrophy	Enrichment	COQ2	2.69
19	Multiple system atrophy, cerebellar type	Enrichment	COQ2	2.69
20	Brown-vialetto-van laere syndrome 2	Enrichment	SLC52A2	2.51
21	Neuronopathy, distal hereditary motor, autosomal recessive 9	Enrichment	COQ7	2.51
22	Coenzyme q10 deficiency, primary, 8	Enrichment	COQ7	2.51
23	Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia	Enrichment	APTX	2.38
24	Full schwannomatosis	Enrichment	COQ6	2.38
25	Focal segmental glomerulosclerosis	Enrichment	COQ2	1.69
26	Auditory neuropathy	Enrichment	SLC52A2	1.58
27	Epilepsy	Enrichment	APTX	1.39
28	Hypertrophic cardiomyopathy	Enrichment	ETFDH	1.36
29	Sensorineural hearing loss	Enrichment	SLC52A2	1.31
30	Mitochondrial disease	Enrichment	COQ8A	1.06
31	Congenital nervous system abnormality	Enrichment	COQ8A	0.98
32	Nervous system disease	Enrichment	COQ8A	0.98

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Riboflavin and CoQ disorders

Pathway Network for Riboflavin and CoQ disorders

Member Pathways for Riboflavin and CoQ disorders

Pathways in the Riboflavin and CoQ disorders SuperPath

Associated Genes for Riboflavin and CoQ disorders

Associated Disorders for Riboflavin and CoQ disorders

Disorders associated with Riboflavin and CoQ disorders SuperPath

STRING Interaction Network for Riboflavin and CoQ disorders

Sources for Riboflavin and CoQ disorders