RNA Polymerase II Transcription Initiation And Promoter Clearance

Pathway network for the RNA Polymerase II Transcription Initiation And Promoter Clearance SuperPath

Sources:

Reactome
GeneGo (Thomson Reuters)
QIAGEN
WikiPathways

Pathways in the RNA Polymerase II Transcription Initiation And Promoter Clearance SuperPath

#	Name	Source	Genes
1	RNA Polymerase II Transcription Initiation And Promoter Clearance	Reactome	CCNH CDK7 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MNAT1 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF3 TAF4 TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TBP (see all 47) (see less)
2	Transcription Ligand-Dependent Transcription of Retinoid-Target genes	GeneGo (Thomson Reuters)	CARM1 CCNC CCND3 CCNH CDK7 CDK8 CRABP2 CREBBP EP300 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 HDAC1 HDAC2 KAT2B MED1 MED10 MED12 MED13 MED14 MED16 MED17 MED20 MED21 MED23 MED24 MED27 MED30 MED31 MED4 MED6 MED7 MNAT1 NCOA1 NCOA2 NCOA3 NCOR1 NCOR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J2 POLR2K POLR2L PRKACA PRKACB PRKACG PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 RARA RBBP4 RBBP7 RXRA SAP130 SAP18 SAP30 SIN3A SUPT3H TADA2A TADA3 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF2 TAF3 TAF4 TAF4B TAF5 TAF5L TAF6 TAF6L TAF7 TAF7L TAF8 TAF9 TAF9B TBP (see all 129) (see less)
3	Crosstalk Between CARM1 and ESRs	QIAGEN	ARHGDIA ARHGDIB ARHGDIG CARM1 CREBBP DIRAS3 EP300 ESR1 ESR2 GRIP1 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 H3-3A H3-3B H3-4 H3C1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H4C1 H4C11 H4C12 H4C13 H4C14 H4C2 H4C3 H4C4 H4C5 H4C6 H4C7 H4C8 H4C9 HAT1 KAT2B MEF2A MEF2C MEF2D NCOA1 NCOA3 POLR2A POLR2B POLR2C PRMT1 RHOA RHOB RHOC RHOD RHOG RHOH RND2 RND3 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1A TAF1B TAF1C TAF1L TAF2 TAF4 TAF5 TAF5L TAF6 TAF6L TAF7 TAF7L TAF9 TAF9B TBP (see all 86) (see less)
4	Protein Acetylation and Deacetylation	QIAGEN	CREBBP EP300 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 HAT1 HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 KAT2B NCOA1 NCOA3 NCOR2 POLR2A POLR2B POLR2C SIN3A SIN3B TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1A TAF1B TAF1C TAF1L TAF2 TAF4 TAF5 TAF5L TAF6 TAF6L TAF7 TAF7L TAF9 TAF9B TBP (see all 55) (see less)
5	RNA Polymerase II Transcription Initiation	Reactome	CCNH CDK7 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MNAT1 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF3 TAF4 TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TBP (see all 47) (see less)
6	RNA Polymerase II Promoter Escape	Reactome	CCNH CDK7 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MNAT1 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF3 TAF4 TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TBP (see all 47) (see less)
7	HIV Transcription Initiation	Reactome	CCNH CDK7 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MNAT1 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF3 TAF4 TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TBP (see all 47) (see less)
8	RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	Reactome	CCNH CDK7 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MNAT1 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF3 TAF4 TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TBP (see all 47) (see less)
9	RNA Polymerase II HIV Promoter Escape	Reactome	CCNH CDK7 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MNAT1 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF3 TAF4 TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TBP (see all 47) (see less)
10	Transcription of mRNA	QIAGEN	GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2I POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2K POLR2L TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF4 TAF5 TAF5L TAF6 TAF6L TAF7 TAF7L TAF9 TAF9B TBP TCEA1 TCEA2 TCEA3 (see all 45) (see less)
11	Assembly of RNA Polymerase-II Initiation Complex	QIAGEN	GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2K POLR2L TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF4 TAF5 TAF5L TAF6 TAF6L TAF7 TAF7L TAF9 TAF9B TBP (see all 41) (see less)
12	Eukaryotic transcription initiation	WikiPathways	CCNH CDK7 ERCC2 ERCC3 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 ILK MNAT1 POLR1A POLR1B POLR1D POLR1E POLR2A POLR2B POLR2C POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR3B POLR3D POLR3E POLR3H POLR3K TAF12 TAF13 TAF5 TAF6 TAF7 TAF9 TBP (see all 41) (see less)

Gene overlap in member pathways for RNA Polymerase II Transcription Initiation And Promoter Clearance SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	GTF2A2	General Transcription Factor IIA Subunit 2	Protein Coding	12
2	GTF2B	General Transcription Factor IIB	Protein Coding	12
3	GTF2H1	General Transcription Factor IIH Subunit 1	Protein Coding	12
4	GTF2H2	General Transcription Factor IIH Subunit 2	Protein Coding	12
5	GTF2H3	General Transcription Factor IIH Subunit 3	Protein Coding	12
6	GTF2H4	General Transcription Factor IIH Subunit 4	Protein Coding	12
7	POLR2A	RNA Polymerase II Subunit A	Protein Coding	12
8	POLR2B	RNA Polymerase II Subunit B	Protein Coding	12
9	POLR2C	RNA Polymerase II Subunit C	Protein Coding	12
10	TAF5	TATA-Box Binding Protein Associated Factor 5	Protein Coding	12
11	TAF6	TATA-Box Binding Protein Associated Factor 6	Protein Coding	12
12	TAF7	TATA-Box Binding Protein Associated Factor 7	Protein Coding	12
13	TAF9	TATA-Box Binding Protein Associated Factor 9	Protein Coding	12
14	TAF12	TATA-Box Binding Protein Associated Factor 12	Protein Coding	12
15	TAF13	TATA-Box Binding Protein Associated Factor 13	Protein Coding	12
16	TBP	TATA-Box Binding Protein	Protein Coding	12
17	GTF2A1	General Transcription Factor IIA Subunit 1	Protein Coding	11
18	GTF2E1	General Transcription Factor IIE Subunit 1	Protein Coding	11
19	GTF2E2	General Transcription Factor IIE Subunit 2	Protein Coding	11
20	GTF2F2	General Transcription Factor IIF Subunit 2	Protein Coding	11
21	GTF2H5	General Transcription Factor IIH Subunit 5	Protein Coding	11
22	TAF9B	TATA-Box Binding Protein Associated Factor 9b	Protein Coding	11
23	TAF7L	TATA-Box Binding Protein Associated Factor 7 Like	Protein Coding	11
24	TAF1	TATA-Box Binding Protein Associated Factor 1	Protein Coding	11
25	TAF2	TATA-Box Binding Protein Associated Factor 2	Protein Coding	11
26	TAF4	TATA-Box Binding Protein Associated Factor 4	Protein Coding	11
27	TAF10	TATA-Box Binding Protein Associated Factor 10	Protein Coding	11
28	TAF11	TATA-Box Binding Protein Associated Factor 11	Protein Coding	11
29	TAF15	TATA-Box Binding Protein Associated Factor 15	Protein Coding	11
30	TAF1L	TATA-Box Binding Protein Associated Factor 1 Like	Protein Coding	10
31	GTF2F1	General Transcription Factor IIF Subunit 1	Protein Coding	10
32	POLR2E	RNA Polymerase II, I And III Subunit E	Protein Coding	10
33	POLR2F	RNA Polymerase II, I And III Subunit F	Protein Coding	10
34	POLR2G	RNA Polymerase II Subunit G	Protein Coding	10
35	POLR2H	RNA Polymerase II, I And III Subunit H	Protein Coding	10
36	POLR2I	RNA Polymerase II Subunit I	Protein Coding	10
37	POLR2K	RNA Polymerase II, I And III Subunit K	Protein Coding	10
38	POLR2D	RNA Polymerase II Subunit D	Protein Coding	9
39	POLR2L	RNA Polymerase II, I And III Subunit L	Protein Coding	9
40	CDK7	Cyclin Dependent Kinase 7	Protein Coding	8
41	ERCC2	ERCC Excision Repair 2, TFIIH Core Complex Helicase Subunit	Protein Coding	8
42	ERCC3	ERCC Excision Repair 3, TFIIH Core Complex Helicase Subunit	Protein Coding	8
43	MNAT1	MNAT1 Component Of CDK Activating Kinase	Protein Coding	8
44	POLR2J	RNA Polymerase II Subunit J	Protein Coding	8
45	CCNH	Cyclin H	Protein Coding	8
46	TAF4B	TATA-Box Binding Protein Associated Factor 4b	Protein Coding	7
47	TAF3	TATA-Box Binding Protein Associated Factor 3	Protein Coding	7
48	TAF6L	TATA-Box Binding Protein Associated Factor 6 Like	Protein Coding	5
49	TAF5L	TATA-Box Binding Protein Associated Factor 5 Like	Protein Coding	5
50	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	3
51	EP300	EP300 Lysine Acetyltransferase	Protein Coding	3
52	NCOA3	Nuclear Receptor Coactivator 3	Protein Coding	3
53	NCOA1	Nuclear Receptor Coactivator 1	Protein Coding	3
54	KAT2B	Lysine Acetyltransferase 2B	Protein Coding	3
55	HDAC1	Histone Deacetylase 1	Protein Coding	2
56	HDAC2	Histone Deacetylase 2	Protein Coding	2
57	NCOR2	Nuclear Receptor Corepressor 2	Protein Coding	2
58	CARM1	Coactivator Associated Arginine Methyltransferase 1	Protein Coding	2
59	SIN3A	SIN3 Transcription Regulator Family Member A	Protein Coding	2
60	HAT1	Histone Acetyltransferase 1	Protein Coding	2
61	TAF1A	TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit A	Protein Coding	2
62	TAF1B	TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit B	Protein Coding	2
63	TAF1C	TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit C	Protein Coding	2
64	CCNC	Cyclin C	Protein Coding	1
65	CCND3	Cyclin D3	Protein Coding	1
66	CDK8	Cyclin Dependent Kinase 8	Protein Coding	1
67	CRABP2	Cellular Retinoic Acid Binding Protein 2	Protein Coding	1
68	MED1	Mediator Complex Subunit 1	Protein Coding	1
69	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
70	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	1
71	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	1
72	PSMA1	Proteasome 20S Subunit Alpha 1	Protein Coding	1
73	PSMA2	Proteasome 20S Subunit Alpha 2	Protein Coding	1
74	PSMA3	Proteasome 20S Subunit Alpha 3	Protein Coding	1
75	PSMA4	Proteasome 20S Subunit Alpha 4	Protein Coding	1
76	PSMA5	Proteasome 20S Subunit Alpha 5	Protein Coding	1
77	PSMA6	Proteasome 20S Subunit Alpha 6	Protein Coding	1
78	PSMA7	Proteasome 20S Subunit Alpha 7	Protein Coding	1
79	PSMB1	Proteasome 20S Subunit Beta 1	Protein Coding	1
80	PSMB2	Proteasome 20S Subunit Beta 2	Protein Coding	1
81	PSMB3	Proteasome 20S Subunit Beta 3	Protein Coding	1
82	PSMB4	Proteasome 20S Subunit Beta 4	Protein Coding	1
83	PSMB5	Proteasome 20S Subunit Beta 5	Protein Coding	1
84	PSMB6	Proteasome 20S Subunit Beta 6	Protein Coding	1
85	PSMB7	Proteasome 20S Subunit Beta 7	Protein Coding	1
86	PSMC1	Proteasome 26S Subunit, ATPase 1	Protein Coding	1
87	PSMC2	Proteasome 26S Subunit, ATPase 2	Protein Coding	1
88	PSMC3	Proteasome 26S Subunit, ATPase 3	Protein Coding	1
89	PSMC4	Proteasome 26S Subunit, ATPase 4	Protein Coding	1
90	PSMC5	Proteasome 26S Subunit, ATPase 5	Protein Coding	1
91	PSMC6	Proteasome 26S Subunit, ATPase 6	Protein Coding	1
92	PSMD1	Proteasome 26S Subunit, Non-ATPase 1	Protein Coding	1
93	PSMD2	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 2	Protein Coding	1
94	PSMD3	Proteasome 26S Subunit, Non-ATPase 3	Protein Coding	1
95	PSMD4	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 4	Protein Coding	1
96	PSMD5	Proteasome 26S Subunit, Non-ATPase 5	Protein Coding	1
97	PSMD7	Proteasome 26S Subunit, Non-ATPase 7	Protein Coding	1
98	PSMD8	Proteasome 26S Subunit, Non-ATPase 8	Protein Coding	1
99	PSMD9	Proteasome 26S Subunit, Non-ATPase 9	Protein Coding	1
100	PSMD10	Proteasome 26S Subunit, Non-ATPase 10	Protein Coding	1
101	PSMD11	Proteasome 26S Subunit, Non-ATPase 11	Protein Coding	1
102	PSMD12	Proteasome 26S Subunit, Non-ATPase 12	Protein Coding	1
103	PSMD13	Proteasome 26S Subunit, Non-ATPase 13	Protein Coding	1
104	RARA	Retinoic Acid Receptor Alpha	Protein Coding	1
105	RBBP4	RB Binding Protein 4, Chromatin Remodeling Factor	Protein Coding	1
106	RBBP7	RB Binding Protein 7, Chromatin Remodeling Factor	Protein Coding	1
107	RXRA	Retinoid X Receptor Alpha	Protein Coding	1
108	TADA2A	Transcriptional Adaptor 2A	Protein Coding	1
109	SUPT3H	SPT3 Homolog, SAGA And STAGA Complex Component	Protein Coding	1
110	SAP30	Sin3A Associated Protein 30	Protein Coding	1
111	MED14	Mediator Complex Subunit 14	Protein Coding	1
112	MED21	Mediator Complex Subunit 21	Protein Coding	1
113	MED23	Mediator Complex Subunit 23	Protein Coding	1
114	MED17	Mediator Complex Subunit 17	Protein Coding	1
115	MED27	Mediator Complex Subunit 27	Protein Coding	1
116	MED7	Mediator Complex Subunit 7	Protein Coding	1
117	MED20	Mediator Complex Subunit 20	Protein Coding	1
118	NCOR1	Nuclear Receptor Corepressor 1	Protein Coding	1
119	PSMD6	Proteasome 26S Subunit, Non-ATPase 6	Protein Coding	1
120	MED24	Mediator Complex Subunit 24	Protein Coding	1
121	MED12	Mediator Complex Subunit 12	Protein Coding	1
122	MED13	Mediator Complex Subunit 13	Protein Coding	1
123	MED6	Mediator Complex Subunit 6	Protein Coding	1
124	MED16	Mediator Complex Subunit 16	Protein Coding	1
125	PSMD14	Proteasome 26S Subunit, Non-ATPase 14	Protein Coding	1
126	SAP18	Sin3A Associated Protein 18	Protein Coding	1
127	TADA3	Transcriptional Adaptor 3	Protein Coding	1
128	NCOA2	Nuclear Receptor Coactivator 2	Protein Coding	1
129	MED4	Mediator Complex Subunit 4	Protein Coding	1
130	MED31	Mediator Complex Subunit 31	Protein Coding	1
131	SAP130	Sin3A Associated Protein 130	Protein Coding	1
132	MED10	Mediator Complex Subunit 10	Protein Coding	1
133	MED30	Mediator Complex Subunit 30	Protein Coding	1
134	TAF8	TATA-Box Binding Protein Associated Factor 8	Protein Coding	1
135	PSMA8	Proteasome 20S Subunit Alpha 8	Protein Coding	1
136	POLR2J2	RNA Polymerase II Subunit J2	Protein Coding	1
137	RHOA	Ras Homolog Family Member A	Protein Coding	1
138	RHOB	Ras Homolog Family Member B	Protein Coding	1
139	RHOC	Ras Homolog Family Member C	Protein Coding	1
140	RHOD	Ras Homolog Family Member D	Protein Coding	1
141	RND3	Rho Family GTPase 3	Protein Coding	1
142	RHOG	Ras Homolog Family Member G	Protein Coding	1
143	ARHGDIA	Rho GDP Dissociation Inhibitor Alpha	Protein Coding	1
144	ARHGDIB	Rho GDP Dissociation Inhibitor Beta	Protein Coding	1
145	ARHGDIG	Rho GDP Dissociation Inhibitor Gamma	Protein Coding	1
146	RHOH	Ras Homolog Family Member H	Protein Coding	1
147	DIRAS3	DIRAS Family GTPase 3	Protein Coding	1
148	RND2	Rho Family GTPase 2	Protein Coding	1
149	ESR1	Estrogen Receptor 1	Protein Coding	1
150	ESR2	Estrogen Receptor 2	Protein Coding	1
151	GRIP1	Glutamate Receptor Interacting Protein 1	Protein Coding	1
152	H3-3A	H3.3 Histone A	Protein Coding	1
153	H3-3B	H3.3 Histone B	Protein Coding	1
154	H3C1	H3 Clustered Histone 1	Protein Coding	1
155	H3C2	H3 Clustered Histone 2	Protein Coding	1
156	H3C3	H3 Clustered Histone 3	Protein Coding	1
157	H3C4	H3 Clustered Histone 4	Protein Coding	1
158	H3C6	H3 Clustered Histone 6	Protein Coding	1
159	H3C7	H3 Clustered Histone 7	Protein Coding	1
160	H3C8	H3 Clustered Histone 8	Protein Coding	1
161	H3C10	H3 Clustered Histone 10	Protein Coding	1
162	H3C11	H3 Clustered Histone 11	Protein Coding	1
163	H3C12	H3 Clustered Histone 12	Protein Coding	1
164	H4C1	H4 Clustered Histone 1	Protein Coding	1
165	H4C2	H4 Clustered Histone 2	Protein Coding	1
166	H4C3	H4 Clustered Histone 3	Protein Coding	1
167	H4C4	H4 Clustered Histone 4	Protein Coding	1
168	H4C5	H4 Clustered Histone 5	Protein Coding	1
169	H4C6	H4 Clustered Histone 6	Protein Coding	1
170	H4C7	H4 Clustered Histone 7	Protein Coding	1
171	H4C8	H4 Clustered Histone 8	Protein Coding	1
172	H4C9	H4 Clustered Histone 9	Protein Coding	1
173	H4C11	H4 Clustered Histone 11	Protein Coding	1
174	H4C12	H4 Clustered Histone 12	Protein Coding	1
175	H4C13	H4 Clustered Histone 13	Protein Coding	1
176	H4C14	H4 Clustered Histone 14	Protein Coding	1
177	H3-4	H3.4 Histone, Cluster Member	Protein Coding	1
178	PRMT1	Protein Arginine Methyltransferase 1	Protein Coding	1
179	MEF2A	Myocyte Enhancer Factor 2A	Protein Coding	1
180	MEF2C	Myocyte Enhancer Factor 2C	Protein Coding	1
181	MEF2D	Myocyte Enhancer Factor 2D	Protein Coding	1
182	HDAC10	Histone Deacetylase 10	Protein Coding	1
183	HDAC11	Histone Deacetylase 11	Protein Coding	1
184	HDAC3	Histone Deacetylase 3	Protein Coding	1
185	HDAC5	Histone Deacetylase 5	Protein Coding	1
186	HDAC6	Histone Deacetylase 6	Protein Coding	1
187	HDAC7	Histone Deacetylase 7	Protein Coding	1
188	HDAC8	Histone Deacetylase 8	Protein Coding	1
189	HDAC9	Histone Deacetylase 9	Protein Coding	1
190	SIN3B	SIN3 Transcription Regulator Family Member B	Protein Coding	1
191	GTF2I	General Transcription Factor IIi	Protein Coding	1
192	TCEA1	Transcription Elongation Factor A1	Protein Coding	1
193	TCEA2	Transcription Elongation Factor A2	Protein Coding	1
194	TCEA3	Transcription Elongation Factor A3	Protein Coding	1
195	POLR3B	RNA Polymerase III Subunit B	Protein Coding	1
196	POLR3K	RNA Polymerase III Subunit K	Protein Coding	1
197	POLR1D	RNA Polymerase I And III Subunit D	Protein Coding	1
198	ILK	Integrin Linked Kinase	Protein Coding	1
199	POLR1A	RNA Polymerase I Subunit A	Protein Coding	1
200	POLR3H	RNA Polymerase III Subunit H	Protein Coding	1
201	POLR1B	RNA Polymerase I Subunit B	Protein Coding	1
202	POLR3D	RNA Polymerase III Subunit D	Protein Coding	1
203	POLR1E	RNA Polymerase I Subunit E	Protein Coding	1
204	POLR3E	RNA Polymerase III Subunit E	Protein Coding	1

Disorders associated with RNA Polymerase II Transcription Initiation And Promoter Clearance SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Human immunodeficiency virus infectious disease	Direct
2	Trichothiodystrophy	Enrichment	ERCC2, ERCC3, GTF2E2, GTF2H5	7.80
3	Witteveen-kolk syndrome	Enrichment	SIN3A, SIN3B	4.79
4	Tessadori-bicknell-van haaften neurodevelopmental syndrome 1	Enrichment	H4C1, H4C3	4.40
5	Tessadori-bicknell-van haaften neurodevelopmental syndrome 2	Enrichment	H4C1, H4C11	4.40
6	Bryant-li-bhoj neurodevelopmental syndrome 2	Enrichment	H3-3A, H3-3B	4.40
7	Xeroderma pigmentosum-cockayne syndrome complex	Enrichment	ERCC2, ERCC3	4.05
8	Tessadori-bicknell-van haaften neurodevelopmental syndrome 4	Enrichment	H4C1, H4C9	3.93
9	Tessadori-bicknell-van haaften neurodevelopmental syndrome 3	Enrichment	H4C1, H4C5	3.93
10	Treacher collins syndrome 1	Enrichment	POLR1B, POLR1D	3.73
11	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	3.62
12	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	3.62
13	Corpus callosum, agenesis of	Enrichment	CREBBP, ERCC2, MED12	3.45
14	Isolated corpus callosum agenesis	Enrichment	CREBBP, ERCC2, MED12	3.45
15	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP, ERCC2, MED12	3.45
16	Xeroderma pigmentosum, variant type	Enrichment	ERCC2, ERCC3	3.32
17	Cornelia de lange syndrome 1	Enrichment	HDAC8, TAF6	3.24
18	Cornelia de lange syndrome	Enrichment	HDAC8, TAF6	3.24
19	Glioma susceptibility 1	Enrichment	H3-3A, H3C1	2.96
20	Leukodystrophy	Enrichment	ERCC2, POLR3B	2.79
21	Rare genetic intellectual disability	Enrichment	CREBBP, EP300	2.79
22	Intellectual developmental disorder, x-linked, syndromic 33	Enrichment	TAF1	2.52
23	Dystonia 3, torsion, x-linked	Enrichment	TAF1	2.52
24	Neurodevelopmental disorder with feeding difficulties, thin corpus callosum, and foot deformity	Enrichment	TAF2	2.52
25	Trichothiodystrophy 6, nonphotosensitive	Enrichment	GTF2E2	2.52
26	Trichothiodystrophy 3, photosensitive	Enrichment	GTF2H5	2.52
27	Alazami-yuan syndrome	Enrichment	TAF6	2.52
28	Intellectual developmental disorder, autosomal recessive 60	Enrichment	TAF13	2.52
29	X-linked intellectual disability-global development delay-facial dysmorphism-sacral caudal remnant syndrome	Enrichment	TAF1	2.52
30	Xeroderma pigmentosum, complementation group b	Enrichment	ERCC3	2.52
31	Leukodystrophy, hypomyelinating, 27	Enrichment	POLR1A	2.52
32	Treacher collins syndrome 4	Enrichment	POLR1B	2.52
33	Xeroderma pigmentosum, complementation group d	Enrichment	ERCC2	2.52
34	Leukodystrophy, hypomyelinating, 21	Enrichment	POLR3K	2.52
35	Trichothiodystrophy 2, photosensitive	Enrichment	ERCC3	2.52
36	Xeroderma pigmentosum group b	Enrichment	ERCC3	2.52
37	Treacher collins syndrome 2	Enrichment	POLR1D	2.52
38	Cerebrooculofacioskeletal syndrome 2	Enrichment	ERCC2	2.52
39	Xeroderma pigmentosum group d	Enrichment	ERCC2	2.52
40	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	2.51
41	Spermatogenic failure 13	Enrichment	TAF4B	2.46
42	Chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia	Enrichment	HDAC6	2.39
43	Auriculocondylar syndrome 4	Enrichment	HDAC9	2.39
44	Cornelia de lange syndrome 5	Enrichment	HDAC8	2.39
45	Menke-hennekam syndrome 1	Enrichment	CREBBP	2.39
46	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	2.39
47	Chromosome 15q24 deletion syndrome	Enrichment	SIN3A	2.39
48	Menke-hennekam syndrome	Enrichment	CREBBP	2.39
49	Spinocerebellar ataxia 17	Enrichment	TBP	2.22
50	Waardenburg syndrome, type 4c	Enrichment	POLR2F	2.22
51	Intellectual developmental disorder, autosomal dominant 73	Enrichment	TAF4	2.22
52	Peripheral demyelinating neuropathy, central dysmyelination, waardenburg syndrome, and hirschsprung disease	Enrichment	POLR2F	2.22
53	Leukodystrophy, hypomyelinating, 8, with or without oligodontia and/or hypogonadotropic hypogonadism	Enrichment	POLR3B	2.22
54	Charcot-marie-tooth disease, demyelinating, type 1i	Enrichment	POLR3B	2.22
55	Acrofacial dysostosis, cincinnati type	Enrichment	POLR1A	2.22
56	Nephrotic syndrome, type 8	Enrichment	ARHGDIA	2.20
57	Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Enrichment	MEF2C	2.20
58	Coronary artery disease, autosomal dominant, 1	Enrichment	MEF2A	2.20
59	Ovarian dysgenesis 8	Enrichment	ESR2	2.20
60	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	2.20
61	Bryant-li-bhoj neurodevelopmental syndrome 1	Enrichment	H3-3A	2.20
62	Fraser syndrome 3	Enrichment	GRIP1	2.20
63	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	2.20
64	Immunodeficiency 129	Enrichment	RHOH	2.20
65	T-cell immunodeficiency with epidermodysplasia verruciformis	Enrichment	RHOH	2.20
66	5q14.3 microdeletion syndrome	Enrichment	MEF2C	2.20
67	Complete atrioventricular septal defect without ventricular hypoplasia	Enrichment	MEF2C	2.20
68	Mef2c-related disorder	Enrichment	MEF2C	2.20
69	Complex neurodevelopmental disorder	Enrichment	CDK8, MED13, MED27, PSMD12, TAF4	2.18
70	Thumb deformity	Enrichment	CREBBP	2.09
71	Syndactyly, type iii	Enrichment	HDAC8	2.09
72	Menke-hennekam syndrome 2	Enrichment	EP300	2.09
73	Wilson-turner syndrome	Enrichment	HDAC8	2.09
74	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	2.09
75	Waardenburg syndrome, type 2a	Enrichment	POLR2F	2.04
76	Trichothiodystrophy 1, photosensitive	Enrichment	ERCC2	2.04
77	Burn-mckeown syndrome	Enrichment	POLR1A	2.04
78	Infantile cerebellar-retinal degeneration	Enrichment	POLR3H	2.04
79	Optic atrophy 9	Enrichment	POLR3H	2.04
80	Viss syndrome	Enrichment	POLR3B	2.04
81	Wieacker-wolff syndrome	Enrichment	CCNH	2.04
82	Polr3-related leukodystrophy	Enrichment	POLR3B	2.04
83	Spermatogenic failure, x-linked, 9	Enrichment	RBBP7	2.02
84	Intellectual developmental disorder, autosomal recessive 18, with or without epilepsy	Enrichment	MED23	2.02
85	Neurodevelopmental disorder with spasticity, cataracts, and cerebellar hypoplasia	Enrichment	MED27	2.02
86	Neurodevelopmental disorder with microcephaly, hypotonia, and absent language	Enrichment	PSMB1	2.02
87	Stankiewicz-isidor syndrome	Enrichment	PSMD12	2.02
88	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	2.02
89	Neurodevelopmental disorder with severe motor impairment, absent language, cerebral hypomyelination, and brain atrophy	Enrichment	TAF8	2.02
90	Deafness, cataract, impaired intellectual development, and polyneuropathy	Enrichment	PSMC3	2.02
91	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	2.02
92	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	2.02
93	Guillouet-gordon syndrome	Enrichment	MED16	2.02
94	Hydrocephalus, congenital, 1	Enrichment	CDK8, MED12	2.01
95	Syndromic intellectual disability	Enrichment	MED16, TAF6	1.95
96	Neurodevelopmental disorder with hypotonia and variable intellectual and behavioral abnormalities	Enrichment	POLR2A	1.92
97	Hypomyelinating leukodystrophy 7	Enrichment	POLR3B	1.92
98	Craniopharyngioma	Enrichment	ERCC2	1.92
99	Tethered spinal cord syndrome	Enrichment	CREBBP	1.92
100	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.92
101	Hypogonadotropic hypogonadism 1 with or without anosmia	Enrichment	POLR2F	1.82
102	Chondrosarcoma, extraskeletal myxoid	Enrichment	TAF15	1.82
103	Capillary malformations, congenital	Enrichment	CCNH	1.82
104	Leukodystrophy, hypomyelinating, 7, with or without oligodontia and/or hypogonadotropic hypogonadism	Enrichment	POLR3B	1.82
105	Myeloma, multiple	Enrichment	CREBBP, NCOR2, RXRA	1.79
106	Waardenburg syndrome, type 4a	Enrichment	POLR2F	1.74
107	Waardenburg syndrome	Enrichment	POLR2F	1.74
108	Klippel-trenaunay-weber syndrome	Enrichment	CCNH	1.74
109	Cerebrooculofacioskeletal syndrome 1	Enrichment	ERCC2	1.74
110	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	CCNH	1.74
111	Hemangioma, capillary infantile	Enrichment	CCNH	1.74
112	Basal cell carcinoma 1	Enrichment	CCNH	1.74
113	Thyroid carcinoma, familial medullary	Enrichment	ESR2	1.72
114	Estrogen resistance	Enrichment	ESR1	1.72
115	Migraine without aura	Enrichment	ESR1	1.72
116	Argininemia	Enrichment	MED23	1.72
117	Ebstein anomaly	Enrichment	CDK8	1.72
118	Hardikar syndrome	Enrichment	MED12	1.72
119	Opitz-kaveggia syndrome	Enrichment	MED12	1.72
120	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.72
121	Birk-aharoni syndrome	Enrichment	PSMC1	1.72
122	Ohdo syndrome, x-linked	Enrichment	MED12	1.72
123	Proteasome-associated autoinflammatory syndrome 3	Enrichment	PSMB4	1.72
124	Fibrolamellar carcinoma	Enrichment	PRKACA	1.72
125	17q24.2 microdeletion syndrome	Enrichment	PSMD12	1.72
126	Cholestasis-pigmentary retinopathy-cleft palate syndrome	Enrichment	MED12	1.72
127	Intellectual developmental disorder with hypotonia and behavioral abnormalities	Enrichment	CDK8	1.72
128	Med12-related disorders	Enrichment	MED12	1.72
129	Blepharophimosis - intellectual disability syndrome, mkb type	Enrichment	MED12	1.72
130	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.70
131	Waardenburg syndrome, type 1	Enrichment	POLR2F	1.68
132	Waardenburg syndrome, type 2e	Enrichment	POLR2F	1.68
133	Capillary malformation-arteriovenous malformation 1	Enrichment	CCNH	1.68
134	Hereditary hemorrhagic telangiectasia	Enrichment	CCNH	1.68
135	Hypertrichosis	Enrichment	CREBBP	1.62
136	Arthrogryposis multiplex congenita 3, myogenic type	Enrichment	ESR1	1.60
137	Inflammatory bowel disease 1	Enrichment	ERCC2	1.57
138	Arteriovenous malformation	Enrichment	CCNH	1.57
139	Hypotrichosis simplex	Enrichment	ERCC2	1.57
140	Cleidocranial dysplasia 1	Enrichment	SUPT3H	1.55
141	Proteasome-associated autoinflammatory syndrome 1	Enrichment	PSMB4	1.55
142	Intellectual developmental disorder, x-linked, syndromic, lujan-fryns type	Enrichment	MED12	1.55
143	Microcephaly, postnatal progressive, with seizures and brain atrophy	Enrichment	MED17	1.55
144	Anus, imperforate	Enrichment	MED12	1.55
145	Intellectual developmental disorder, autosomal dominant 61	Enrichment	MED13	1.55
146	Proteosome-associated autoinflammatory syndrome	Enrichment	PSMB4	1.55
147	Cleidocranial dysplasia	Enrichment	SUPT3H	1.55
148	Thyroid hemiagenesis	Enrichment	PSMD3	1.55
149	Microcephaly	Enrichment	EP300, MED12, PSMC3, TAF8	1.53
150	Myopathy, x-linked, with excessive autophagy	Enrichment	CCNH	1.53
151	Fanconi anemia, complementation group c	Enrichment	HDAC8	1.50
152	46 xx gonadal dysgenesis	Enrichment	POLR3H	1.45
153	Charge syndrome	Enrichment	EP300	1.44
154	Ovarian cancer	Enrichment	ERCC2, ERCC3	1.43
155	Fraser syndrome 1	Enrichment	GRIP1	1.43
156	Hemihyperplasia, isolated	Enrichment	RHOA	1.43
157	Isolated growth hormone deficiency, type ii	Enrichment	MED13	1.43
158	Hypogonadotropic hypogonadism 7 with or without anosmia	Enrichment	POLR3B	1.38
159	Atrial heart septal defect	Enrichment	HDAC8	1.36
160	Interatrial communication	Enrichment	HDAC8	1.36
161	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	MEF2C, TAF15	1.28
162	Heart disease	Enrichment	CREBBP	1.26
163	Developmental dysplasia of the hip 1	Enrichment	PSMC3	1.25
164	Patent ductus arteriosus	Enrichment	PSMC3	1.25
165	Esophageal atresia/tracheoesophageal fistula	Enrichment	POLR2B	1.25
166	Parkinson's disease	Enrichment	TBP	1.25
167	Polydactyly, postaxial, type a1	Enrichment	EP300	1.23
168	Hepatoblastoma	Enrichment	ERCC2	1.21
169	Williams-beuren syndrome	Enrichment	GTF2I	1.19
170	Kallmann syndrome	Enrichment	POLR2F	1.17
171	Migraine with or without aura 1	Enrichment	ESR1	1.17
172	Parkinson disease, late-onset	Enrichment	TBP	1.15
173	Polycystic kidney disease	Enrichment	HDAC8	1.15
174	Diffuse large b-cell lymphoma	Enrichment	CREBBP	1.13
175	Hirschsprung disease 1	Enrichment	POLR2F	1.08
176	Bladder cancer	Enrichment	ERCC2	1.08
177	Polymicrogyria	Enrichment	PSMC3	1.04
178	Primary autosomal recessive microcephaly	Enrichment	TAF13	1.03
179	Scoliosis	Enrichment	CREBBP	1.03
180	Diaphragmatic hernia, congenital	Enrichment	CDK8	0.93
181	Acute promyelocytic leukemia	Enrichment	RARA	0.93
182	Optic atrophy plus syndrome	Enrichment	POLR3H	0.90
183	Myocardial infarction	Enrichment	ESR1	0.88
184	Cardiomyopathy, dilated, 1e	Enrichment	MED12	0.82
185	Heart, malformation of	Enrichment	CDK8	0.80
186	Patent foramen ovale	Enrichment	PSMC3	0.80
187	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	TAF4B	0.75
188	Familial isolated dilated cardiomyopathy	Enrichment	TAF1A	0.71
189	Genetic steroid-resistant nephrotic syndrome	Enrichment	ARHGDIA	0.71
190	Rare genetic deafness	Enrichment	POLR2F	0.67
191	Hereditary breast carcinoma	Enrichment	ESR1	0.61
192	Autism	Enrichment	CREBBP	0.59
193	Non-syndromic x-linked intellectual disability	Enrichment	MED12	0.54
194	Colorectal cancer	Enrichment	EP300	0.52
195	Inherited cancer-predisposing syndrome	Enrichment	ERCC3	0.48
196	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	MED12	0.46
197	Congenital nervous system abnormality	Enrichment	CREBBP	0.45
198	Nervous system disease	Enrichment	CREBBP	0.45
199	Breast cancer	Enrichment	ESR1	0.42
200	Autosomal recessive non-syndromic intellectual disability	Enrichment	MED23	0.37
201	Autism spectrum disorder	Enrichment	MEF2C	0.30

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

RNA Polymerase II Transcription Initiation And Promoter Clearance

Pathway Network for RNA Polymerase II Transcription Initiation And Promoter Clearance

Pathway network for the RNA Polymerase II Transcription Initiation And Promoter Clearance SuperPath

Member Pathways for RNA Polymerase II Transcription Initiation And Promoter Clearance

Pathways in the RNA Polymerase II Transcription Initiation And Promoter Clearance SuperPath

Gene overlap in member pathways for RNA Polymerase II Transcription Initiation And Promoter Clearance SuperPath

Associated Genes for RNA Polymerase II Transcription Initiation And Promoter Clearance

Associated Disorders for RNA Polymerase II Transcription Initiation And Promoter Clearance

Disorders associated with RNA Polymerase II Transcription Initiation And Promoter Clearance SuperPath

STRING Interaction Network for RNA Polymerase II Transcription Initiation And Promoter Clearance

Sources for RNA Polymerase II Transcription Initiation And Promoter Clearance