ROBO receptors bind AKAP5
Pathways in the ROBO receptors bind AKAP5 SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | ROBO receptors bind AKAP5 | Reactome |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | PPP3CB | Protein Phosphatase 3 Catalytic Subunit Beta | Protein Coding | 1 |
| 2 | PRKACA | Protein Kinase CAMP-Activated Catalytic Subunit Alpha | Protein Coding | 1 |
| 3 | PRKACB | Protein Kinase CAMP-Activated Catalytic Subunit Beta | Protein Coding | 1 |
| 4 | PRKACG | Protein Kinase CAMP-Activated Catalytic Subunit Gamma | Protein Coding | 1 |
| 5 | PRKAR2A | Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha | Protein Coding | 1 |
| 6 | PRKCA | Protein Kinase C Alpha | Protein Coding | 1 |
| 7 | ROBO2 | Roundabout Guidance Receptor 2 | Protein Coding | 1 |
| 8 | ROBO3 | Roundabout Guidance Receptor 3 | Protein Coding | 1 |
| 9 | AKAP5 | A-Kinase Anchoring Protein 5 | Protein Coding | 1 |
Disorders associated with ROBO receptors bind AKAP5 SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Ellis-van creveld syndrome | Enrichment | PRKACA, PRKACB | 4.85 |
| 2 | Vesicoureteral reflux 2 | Enrichment | ROBO2 | 3.18 |
| 3 | Cardioacrofacial dysplasia 2 | Enrichment | PRKACB | 3.18 |
| 4 | Conjugate gaze palsy | Enrichment | ROBO3 | 3.18 |
| 5 | Pigmented nodular adrenocortical disease, primary, 4 | Enrichment | PRKACA | 3.18 |
| 6 | Cardioacrofacial dysplasia 1 | Enrichment | PRKACA | 3.18 |
| 7 | Gaze palsy, familial horizontal, with progressive scoliosis 1 | Enrichment | ROBO3 | 2.88 |
| 8 | Bleeding disorder, platelet-type, 19 | Enrichment | PRKACG | 2.88 |
| 9 | Fibrolamellar carcinoma | Enrichment | PRKACA | 2.88 |
| 10 | Horizontal gaze palsy with progressive scoliosis | Enrichment | ROBO3 | 2.88 |
| 11 | Familial vesicoureteral reflux | Enrichment | ROBO2 | 2.70 |