Role of ABL in ROBO-SLIT signaling

No Pathway Network information available for Role of ABL in ROBO-SLIT signaling

#	Name	Source	Genes
1	Role of ABL in ROBO-SLIT signaling	Reactome	ABL1 ABL2 CAP1 CAP2 CLASP1 CLASP2 ROBO1 SLIT2 (see all 8) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CAP2	Cyclase Associated Actin Cytoskeleton Regulatory Protein 2	Protein Coding	1
2	CAP1	Cyclase Associated Actin Cytoskeleton Regulatory Protein 1	Protein Coding	1
3	CLASP2	Cytoplasmic Linker Associated Protein 2	Protein Coding	1
4	CLASP1	Cytoplasmic Linker Associated Protein 1	Protein Coding	1
5	ABL1	ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase	Protein Coding	1
6	ABL2	ABL Proto-Oncogene 2, Non-Receptor Tyrosine Kinase	Protein Coding	1
7	ROBO1	Roundabout Guidance Receptor 1	Protein Coding	1
8	SLIT2	Slit Guidance Ligand 2	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Cakut	Enrichment	ROBO1, SLIT2	3.77
2	Nystagmus 8, congenital, autosomal recessive	Enrichment	ROBO1	3.23
3	Cardiomyopathy, dilated, 2i	Enrichment	CAP2	3.23
4	Autosomal recessive congenital nystagmus	Enrichment	ROBO1	3.23
5	Pituitary hormone deficiency, combined or isolated, 8	Enrichment	ROBO1	3.23
6	Neurooculorenal syndrome	Enrichment	ROBO1	3.23
7	Congenital nystagmus	Enrichment	ROBO1	3.23
8	Microcephalic osteodysplastic primordial dwarfism, type i	Enrichment	CLASP1	2.93
9	Lowry-wood syndrome	Enrichment	CLASP1	2.93
10	Roifman syndrome	Enrichment	CLASP1	2.93
11	Congenital heart defects and skeletal malformations syndrome	Enrichment	ABL1	2.93
12	Rnu4atac-opathy	Enrichment	CLASP1	2.93
13	Spondyloepiphyseal dysplasia congenita	Enrichment	CLASP1	2.75
14	T-cell acute lymphoblastic leukemia	Enrichment	ABL1	2.75
15	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	ABL1	2.63
16	Leukemia, chronic myeloid	Enrichment	ABL1	2.38
17	Moyamoya angiopathy	Enrichment	ABL1	2.38
18	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	ABL1	2.38
19	Renal agenesis, bilateral	Enrichment	ROBO1	2.28
20	Lip and oral cavity carcinoma	Enrichment	ABL1	2.15
21	Heart disease	Enrichment	ABL1	2.08
22	Pituitary stalk interruption syndrome	Enrichment	ROBO1	2.08
23	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ABL1	1.87
24	Tetralogy of fallot	Enrichment	ROBO1	1.82
25	Familial isolated dilated cardiomyopathy	Enrichment	CAP2	1.51
26	Microcephaly	Enrichment	ABL1	1.15

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Role of ABL in ROBO-SLIT signaling