Role of phospholipids in phagocytosis

No Pathway Network information available for Role of phospholipids in phagocytosis

Pathways in the Role of phospholipids in phagocytosis SuperPath

#	Name	Source	Genes
1	Role of phospholipids in phagocytosis	Reactome	AHCYL1 CD247 CD3G FCGR1A FCGR2A FCGR3A ITPR1 ITPR2 ITPR3 PIK3CA PIK3CB PIK3R1 PIK3R2 PLA2G6 PLCG1 PLCG2 PLD1 PLD2 PLD3 PLD4 PLPP4 PLPP5 PRKCD PRKCE SYK (see all 25) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AHCYL1	Adenosylhomocysteinase Like 1	Protein Coding	1
2	PLD4	Phospholipase D Family Member 4	Protein Coding	1
3	PLPP4	Phospholipid Phosphatase 4	Protein Coding	1
4	FCGR1A	Fc Gamma Receptor Ia	Protein Coding	1
5	FCGR2A	Fc Gamma Receptor IIa	Protein Coding	1
6	FCGR3A	Fc Gamma Receptor IIIa	Protein Coding	1
7	PLD3	Phospholipase D Family Member 3	Protein Coding	1
8	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	1
9	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	1
10	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	1
11	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
12	PIK3CB	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta	Protein Coding	1
13	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
14	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	1
15	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
16	PLCG2	Phospholipase C Gamma 2	Protein Coding	1
17	PLD1	Phospholipase D1	Protein Coding	1
18	PLD2	Phospholipase D2	Protein Coding	1
19	PRKCD	Protein Kinase C Delta	Protein Coding	1
20	PRKCE	Protein Kinase C Epsilon	Protein Coding	1
21	SYK	Spleen Associated Tyrosine Kinase	Protein Coding	1
22	PLA2G6	Phospholipase A2 Group VI	Protein Coding	1
23	PLPP5	Phospholipid Phosphatase 5	Protein Coding	1
24	CD3G	CD3 Gamma Subunit Of T-Cell Receptor Complex	Protein Coding	1
25	CD247	CD247 Molecule	Protein Coding	1

Disorders associated with Role of phospholipids in phagocytosis SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	5.01
2	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3CA, PIK3R2	4.71
3	Severe combined immunodeficiency	Enrichment	CD247, CD3G	2.78
4	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	2.73
5	Macrodactyly	Enrichment	PIK3CA	2.73
6	Osteopetrosis and infantile neuroaxonal dystrophy	Enrichment	PLA2G6	2.73
7	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.73
8	Cowden syndrome 5	Enrichment	PIK3CA	2.73
9	Cardiac valvular dysplasia 1	Enrichment	PLD1	2.73
10	Immunodeficiency 20	Enrichment	FCGR3A	2.73
11	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	2.73
12	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.73
13	Immunodeficiency 82 with systemic inflammation	Enrichment	SYK	2.73
14	Neurodegeneration with brain iron accumulation 2a	Enrichment	PLA2G6	2.73
15	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	2.73
16	Short syndrome	Enrichment	PIK3R1	2.73
17	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.73
18	Immunodeficiency 25	Enrichment	CD247	2.73
19	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.73
20	Parkinson disease 14, autosomal recessive	Enrichment	PLA2G6	2.73
21	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.73
22	Neurodegeneration with brain iron accumulation 2b	Enrichment	PLA2G6	2.73
23	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.73
24	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	2.73
25	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.73
26	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	2.73
27	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.73
28	Hypospadias	Enrichment	PIK3CA	2.73
29	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	2.73
30	Colitis	Enrichment	SYK	2.73
31	Systemic lupus erythematosus 18	Enrichment	PLD4	2.73
32	Rare venous malformation	Enrichment	PIK3CA	2.73
33	Diaphragmatic eventration	Enrichment	PIK3CA	2.73
34	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.73
35	Rare combined vascular malformation	Enrichment	PIK3CA	2.73
36	Cavernous lymphangioma	Enrichment	PIK3CA	2.73
37	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.73
38	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.73
39	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.73
40	Macrodactyly of toe	Enrichment	PIK3CA	2.73
41	Spinocerebellar ataxia 29	Enrichment	ITPR1	2.43
42	Charcot-marie-tooth disease, demyelinating, type 4f	Enrichment	PLD3	2.43
43	Keratosis, seborrheic	Enrichment	PIK3CA	2.43
44	Noonan syndrome 8	Enrichment	PIK3CA	2.43
45	Spinocerebellar ataxia 46	Enrichment	PLD3	2.43
46	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	2.43
47	Immunodeficiency 17	Enrichment	CD3G	2.43
48	Charcot-marie-tooth disease type 4f	Enrichment	PLD3	2.43
49	Arthritis	Enrichment	SYK	2.43
50	Infantile osteopetrosis with neuroaxonal dysplasia	Enrichment	PLA2G6	2.43
51	Spastic ataxia	Enrichment	ITPR1, PLA2G6	2.37
52	Gillespie syndrome	Enrichment	ITPR1	2.26
53	Pompe disease, infantile-onset	Enrichment	PIK3CA	2.26
54	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	2.26
55	Immunodeficiency 14	Enrichment	PIK3R1	2.26
56	T-b+ severe combined immunodeficiency due to cd3delta/cd3epsilon/cd3zeta	Enrichment	CD247	2.26
57	Keratoacanthoma	Enrichment	PIK3CA	2.26
58	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	PIK3R2	2.13
59	Spinocerebellar ataxia 15	Enrichment	ITPR1	2.13
60	Cerebrovascular disease	Enrichment	PIK3CA	2.13
61	Familial cerebral cavernous malformations	Enrichment	PIK3CA	2.13
62	Capillary malformations, congenital	Enrichment	PIK3CA	2.04
63	Hemimegalencephaly	Enrichment	PIK3CA	2.04
64	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.96
65	Cowden syndrome 1	Enrichment	PIK3CA	1.96
66	Hemihyperplasia, isolated	Enrichment	PIK3CA	1.96
67	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	1.96
68	Breast adenocarcinoma	Enrichment	PIK3CA	1.96
69	Lung squamous cell carcinoma	Enrichment	PIK3CA	1.96
70	Colorectal cancer	Enrichment	PIK3CA, PIK3R1	1.96
71	Nevus, epidermal	Enrichment	PIK3CA	1.89
72	Capillary malformation-arteriovenous malformation 1	Enrichment	PIK3CA	1.89
73	Gallbladder cancer	Enrichment	PIK3CA	1.89
74	Oligoarticular juvenile idiopathic arthritis	Enrichment	CD247	1.89
75	Overgrowth syndrome	Enrichment	PIK3R1	1.89
76	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	CD247	1.89
77	Arteriovenous malformation	Enrichment	PIK3CA	1.78
78	Adult hepatocellular carcinoma	Enrichment	PIK3CA	1.78
79	Cowden syndrome	Enrichment	PIK3CA	1.78
80	Myopathy, x-linked, with excessive autophagy	Enrichment	PIK3CA	1.74
81	Neurodegeneration with brain iron accumulation	Enrichment	PLA2G6	1.74
82	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	1.74
83	Immune deficiency disease	Enrichment	SYK	1.70
84	Lung non-small cell carcinoma	Enrichment	PIK3CA	1.70
85	Meningioma	Enrichment	PIK3CA	1.66
86	Lip and oral cavity carcinoma	Enrichment	PIK3CA	1.66
87	Congenital long qt syndrome	Enrichment	ITPR3	1.66
88	Nk-cell enteropathy	Enrichment	PIK3CB	1.63
89	Multiple sclerosis	Enrichment	ITPR1	1.59
90	Anterior segment dysgenesis	Enrichment	ITPR1	1.56
91	Lynch syndrome	Enrichment	PIK3CA	1.56
92	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	PLA2G6	1.54
93	Charcot-marie-tooth disease type 4	Enrichment	PLD3	1.49
94	Endometrial cancer	Enrichment	PIK3CA	1.42
95	Hepatocellular carcinoma	Enrichment	PIK3CA	1.40
96	Malaria	Enrichment	FCGR2A	1.38
97	Bladder cancer	Enrichment	PIK3CA	1.28
98	Prostate cancer	Enrichment	PIK3CA	1.28
99	Long qt syndrome 1	Enrichment	ITPR3	1.27
100	Lung cancer	Enrichment	PIK3CA	1.24
101	Cystic fibrosis	Enrichment	FCGR2A	1.24
102	Systemic lupus erythematosus	Enrichment	FCGR2A	1.16
103	Charcot-marie-tooth disease	Enrichment	PLD3	1.14
104	Gastric cancer	Enrichment	PIK3CA	1.12
105	Hereditary breast carcinoma	Enrichment	PIK3CA	1.11
106	Hypertelorism	Enrichment	PIK3CA	1.04
107	Myeloma, multiple	Enrichment	PIK3R2	1.01
108	Breast cancer	Enrichment	PIK3CA	0.89
109	Ovarian cancer	Enrichment	PIK3CA	0.77
110	Congenital nervous system abnormality	Enrichment	PLA2G6	0.75
111	Nervous system disease	Enrichment	PLA2G6	0.75
112	Microcephaly	Enrichment	PLA2G6	0.69

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Role of phospholipids in phagocytosis

Pathway Network for Role of phospholipids in phagocytosis

Member Pathways for Role of phospholipids in phagocytosis

Pathways in the Role of phospholipids in phagocytosis SuperPath

Associated Genes for Role of phospholipids in phagocytosis

Associated Disorders for Role of phospholipids in phagocytosis

Disorders associated with Role of phospholipids in phagocytosis SuperPath

STRING Interaction Network for Role of phospholipids in phagocytosis

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