rRNA processing in the nucleus and cytosol

Pathway network for the rRNA processing in the nucleus and cytosol SuperPath

Sources:

Reactome

Pathways in the rRNA processing in the nucleus and cytosol SuperPath

#	Name	Source	Genes
1	rRNA processing in the nucleus and cytosol	Reactome	BMS1 BOP1 BUD23 BYSL C1D CSNK1D CSNK1E DCAF13 DDX21 DDX47 DDX49 DDX52 DHX37 DIMT1 DIS3 DKC1 EBNA1BP2 EMG1 ERI1 EXOSC1 EXOSC10 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FAU FBL FCF1 FTSJ3 GAR1 GNL3 HEATR1 IMP3 IMP4 ISG20L2 KRR1 LAS1L LTV1 MPHOSPH10 MPHOSPH6 MTREX NAT10 NCL NHP2 NIP7 NOB1 NOC4L NOL11 NOL12 NOL6 NOL9 NOP10 NOP14 NOP2 NOP56 NOP58 PDCD11 PELP1 PES1 PNO1 PWP2 RBM28 RCL1 RIOK1 RIOK2 RIOK3 RNA45SN5 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL3L RPL4 RPL41 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPLP0 RPLP1 RPLP2 RPP14 RPP21 RPP25 RPP30 RPP38 RPP40 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4X RPS4Y1 RPS4Y2 RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 RRP36 RRP7A RRP9 SENP3 SNU13 TBL3 TEX10 THUMPD1 TRMT112 TSR1 TSR3 UBA52 UTP11 UTP14A UTP14C UTP15 UTP18 UTP20 UTP25 UTP3 UTP4 UTP6 WDR12 WDR18 WDR3 WDR36 WDR43 WDR46 WDR75 XRN2 (see all 194) (see less)
2	rRNA processing	Reactome	BMS1 BOP1 BUD23 BYSL C1D CSNK1D CSNK1E DCAF13 DDX21 DDX47 DDX49 DDX52 DHX37 DIMT1 DIS3 DKC1 EBNA1BP2 ELAC2 EMG1 ERI1 EXOSC1 EXOSC10 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FASTKD2 FAU FBL FCF1 FTSJ3 GAR1 GNL3 HEATR1 HSD17B10 IMP3 IMP4 ISG20L2 KRR1 LAS1L LTV1 MPHOSPH10 MPHOSPH6 MRM1 MRM2 MRM3 MTERF3 MTERF4 MTREX NAT10 NCL NGRN NHP2 NIP7 NOB1 NOC4L NOL11 NOL12 NOL6 NOL9 NOP10 NOP14 NOP2 NOP56 NOP58 NSUN4 PDCD11 PELP1 PES1 PNO1 PRORP PWP2 RBM28 RCC1L RCL1 RIOK1 RIOK2 RIOK3 RNA45SN5 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL3L RPL4 RPL41 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPLP0 RPLP1 RPLP2 RPP14 RPP21 RPP25 RPP30 RPP38 RPP40 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4X RPS4Y1 RPS4Y2 RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RPUSD3 RPUSD4 RRP1 RRP36 RRP7A RRP9 SENP3 SNU13 TBL3 TEX10 TFB1M THUMPD1 TRMT10C TRMT112 TRUB2 TSR1 TSR3 UBA52 UTP11 UTP14A UTP14C UTP15 UTP18 UTP20 UTP25 UTP3 UTP4 UTP6 WDR12 WDR18 WDR3 WDR36 WDR43 WDR46 WDR75 XRN2 (see all 211) (see less)
3	Major pathway of rRNA processing in the nucleolus and cytosol	Reactome	BMS1 BOP1 BUD23 BYSL C1D CSNK1D CSNK1E DCAF13 DDX21 DDX47 DDX49 DDX52 DHX37 DIS3 EBNA1BP2 EMG1 ERI1 EXOSC1 EXOSC10 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FAU FBL FCF1 FTSJ3 GNL3 HEATR1 IMP3 IMP4 ISG20L2 KRR1 LAS1L LTV1 MPHOSPH10 MPHOSPH6 MTREX NCL NIP7 NOB1 NOC4L NOL11 NOL12 NOL6 NOL9 NOP14 NOP56 NOP58 PDCD11 PELP1 PES1 PNO1 PWP2 RBM28 RCL1 RIOK1 RIOK2 RIOK3 RNA45SN5 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL3L RPL4 RPL41 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPLP0 RPLP1 RPLP2 RPP14 RPP21 RPP25 RPP30 RPP38 RPP40 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4X RPS4Y1 RPS4Y2 RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 RRP36 RRP7A RRP9 SENP3 SNU13 TBL3 TEX10 TSR1 UBA52 UTP11 UTP14A UTP14C UTP15 UTP18 UTP20 UTP25 UTP3 UTP4 UTP6 WDR12 WDR18 WDR3 WDR36 WDR43 WDR46 WDR75 XRN2 (see all 184) (see less)
4	rRNA modification in the nucleus and cytosol	Reactome	BMS1 BUD23 DCAF13 DDX47 DDX49 DDX52 DHX37 DIMT1 DKC1 EMG1 FBL FCF1 GAR1 HEATR1 IMP3 IMP4 KRR1 MPHOSPH10 NAT10 NHP2 NOC4L NOL11 NOL6 NOP10 NOP14 NOP2 NOP56 NOP58 PDCD11 PNO1 PWP2 RCL1 RNA45SN5 RPS14 RPS2 RPS6 RPS7 RPS9 RRP36 RRP7A RRP9 SNU13 TBL3 THUMPD1 TRMT112 TSR3 UTP11 UTP14A UTP14C UTP15 UTP18 UTP20 UTP25 UTP3 UTP4 UTP6 WDR3 WDR36 WDR43 WDR46 WDR75 (see all 61) (see less)

Gene overlap in member pathways for rRNA processing in the nucleus and cytosol SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RNA45SN5	RNA, 45S Pre-Ribosomal N5	RNA Gene	4
2	RCL1	RNA Terminal Phosphate Cyclase Like 1	Protein Coding	4
3	MPHOSPH10	M-Phase Phosphoprotein 10	Protein Coding	4
4	EMG1	EMG1 N1-Specific Pseudouridine Methyltransferase	Protein Coding	4
5	NOP56	NOP56 Ribonucleoprotein	Protein Coding	4
6	TBL3	Transducin Beta Like 3	Protein Coding	4
7	UTP14A	UTP14A Small Subunit Processome Component	Protein Coding	4
8	WDR3	WD Repeat Domain 3	Protein Coding	4
9	DDX52	DExD-Box Helicase 52	Protein Coding	4
10	KRR1	KRR1 Small Subunit Processome Component	Protein Coding	4
11	BUD23	BUD23 RRNA Methyltransferase And Ribosome Maturation Factor	Protein Coding	4
12	WDR36	WD Repeat Domain 36	Protein Coding	4
13	FBL	Fibrillarin	Protein Coding	4
14	PDCD11	Programmed Cell Death 11	Protein Coding	4
15	WDR43	WD Repeat Domain 43	Protein Coding	4
16	DCAF13	DDB1 And CUL4 Associated Factor 13	Protein Coding	4
17	NOL11	Nucleolar Protein 11	Protein Coding	4
18	UTP25	UTP25 Small Subunit Processome Component	Protein Coding	4
19	UTP20	UTP20 Small Subunit Processome Component	Protein Coding	4
20	RRP7A	Ribosomal RNA Processing 7 Homolog A	Protein Coding	4
21	SNU13	Small Nuclear Ribonucleoprotein 13	Protein Coding	4
22	FCF1	FCF1 RRNA-Processing Protein	Protein Coding	4
23	UTP18	UTP18 Small Subunit Processome Component	Protein Coding	4
24	UTP11	UTP11 Small Subunit Processome Component	Protein Coding	4
25	DDX47	DEAD-Box Helicase 47	Protein Coding	4
26	NOP58	NOP58 Ribonucleoprotein	Protein Coding	4
27	DDX49	DEAD-Box Helicase 49	Protein Coding	4
28	HEATR1	HEAT Repeat Containing 1	Protein Coding	4
29	IMP3	IMP U3 Small Nucleolar Ribonucleoprotein 3	Protein Coding	4
30	UTP6	UTP6 Small Subunit Processome Component	Protein Coding	4
31	PNO1	Partner Of NOB1 Homolog	Protein Coding	4
32	UTP3	UTP3 Small Subunit Processome Component	Protein Coding	4
33	DHX37	DEAH-Box Helicase 37	Protein Coding	4
34	PWP2	PWP2 Small Subunit Processome Component	Protein Coding	4
35	RPS2	Ribosomal Protein S2	Protein Coding	4
36	RPS6	Ribosomal Protein S6	Protein Coding	4
37	RPS7	Ribosomal Protein S7	Protein Coding	4
38	RPS9	Ribosomal Protein S9	Protein Coding	4
39	RPS14	Ribosomal Protein S14	Protein Coding	4
40	NOL6	Nucleolar Protein 6	Protein Coding	4
41	NOC4L	Nucleolar Complex Associated 4 Homolog	Protein Coding	4
42	WDR75	WD Repeat Domain 75	Protein Coding	4
43	UTP15	UTP15 Small Subunit Processome Component	Protein Coding	4
44	UTP4	UTP4 Small Subunit Processome Component	Protein Coding	4
45	NOP14	NOP14 Nucleolar Protein	Protein Coding	4
46	RRP36	Ribosomal RNA Processing 36	Protein Coding	4
47	RRP9	Ribosomal RNA Processing 9, U3 Small Nucleolar RNA Binding Protein	Protein Coding	4
48	WDR46	WD Repeat Domain 46	Protein Coding	4
49	IMP4	IMP U3 Small Nucleolar Ribonucleoprotein 4	Protein Coding	4
50	UTP14C	UTP14C Small Subunit Processome Component	Protein Coding	4
51	BMS1	BMS1 Ribosome Biogenesis Factor	Protein Coding	4
52	MPHOSPH6	M-Phase Phosphoprotein 6	Protein Coding	3
53	C1D	C1D Nuclear Receptor Corepressor	Protein Coding	3
54	RPP30	Ribonuclease P/MRP Subunit P30	Protein Coding	3
55	RPP38	Ribonuclease P/MRP Subunit P38	Protein Coding	3
56	RPP40	Ribonuclease P/MRP Subunit P40	Protein Coding	3
57	EBNA1BP2	EBNA1 Binding Protein 2	Protein Coding	3
58	RPP14	Ribonuclease P/MRP Subunit P14	Protein Coding	3
59	RPL35	Ribosomal Protein L35	Protein Coding	3
60	EXOSC8	Exosome Component 8	Protein Coding	3
61	TSR3	TSR3 Ribosome Maturation Factor	Protein Coding	3
62	RPL39L	Ribosomal Protein L39 Like	Protein Coding	3
63	FTSJ3	FtsJ RNA 2''-O-Methyltransferase 3	Protein Coding	3
64	EXOSC6	Exosome Component 6	Protein Coding	3
65	RPS4Y2	Ribosomal Protein S4 Y-Linked 2	Protein Coding	3
66	RPL10L	Ribosomal Protein L10 Like	Protein Coding	3
67	CSNK1D	Casein Kinase 1 Delta	Protein Coding	3
68	CSNK1E	Casein Kinase 1 Epsilon	Protein Coding	3
69	DKC1	Dyskerin Pseudouridine Synthase 1	Protein Coding	3
70	RPL22L1	Ribosomal Protein L22 Like 1	Protein Coding	3
71	FAU	FAU Ubiquitin Like And Ribosomal Protein S30 Fusion	Protein Coding	3
72	XRN2	5''-3'' Exoribonuclease 2	Protein Coding	3
73	DIS3	DIS3 Exosome Endoribonuclease And 3''''-5'''' Exoribonuclease	Protein Coding	3
74	EXOSC7	Exosome Component 7	Protein Coding	3
75	BOP1	BOP1 Ribosomal Biogenesis Factor	Protein Coding	3
76	EXOSC2	Exosome Component 2	Protein Coding	3
77	PES1	Pescadillo Ribosomal Biogenesis Factor 1	Protein Coding	3
78	MTREX	Mtr4 Exosome RNA Helicase	Protein Coding	3
79	RPL13A	Ribosomal Protein L13a	Protein Coding	3
80	RPL36	Ribosomal Protein L36	Protein Coding	3
81	SENP3	SUMO Specific Peptidase 3	Protein Coding	3
82	GNL3	G Protein Nucleolar 3	Protein Coding	3
83	PELP1	Proline, Glutamate And Leucine Rich Protein 1	Protein Coding	3
84	DIMT1	DIM1 RRNA Methyltransferase And Ribosome Maturation Factor	Protein Coding	3
85	NOB1	NIN1 (RPN12) Binding Protein 1 Homolog	Protein Coding	3
86	RPSA	Ribosomal Protein SA	Protein Coding	3
87	NCL	Nucleolin	Protein Coding	3
88	RPL10A	Ribosomal Protein L10a	Protein Coding	3
89	NOP2	NOP2 Nucleolar Protein	Protein Coding	3
90	EXOSC3	Exosome Component 3	Protein Coding	3
91	EXOSC1	Exosome Component 1	Protein Coding	3
92	RPS27L	Ribosomal Protein S27 Like	Protein Coding	3
93	RPL26L1	Ribosomal Protein L26 Like 1	Protein Coding	3
94	NIP7	Nucleolar Pre-RRNA Processing Protein NIP7	Protein Coding	3
95	TRMT112	TRNA Methyltransferase Activator Subunit 11-2	Protein Coding	3
96	EXOSC9	Exosome Component 9	Protein Coding	3
97	EXOSC10	Exosome Component 10	Protein Coding	3
98	GAR1	GAR1 Ribonucleoprotein	Protein Coding	3
99	EXOSC4	Exosome Component 4	Protein Coding	3
100	TEX10	Testis Expressed 10	Protein Coding	3
101	RPP25	Ribonuclease P/MRP Subunit P25	Protein Coding	3
102	RBM28	RNA Binding Motif Protein 28	Protein Coding	3
103	NAT10	N-Acetyltransferase 10	Protein Coding	3
104	NOP10	NOP10 Ribonucleoprotein	Protein Coding	3
105	THUMPD1	THUMP Domain 1 NAT10 Acetyltransferase Adaptor	Protein Coding	3
106	NHP2	NHP2 Ribonucleoprotein	Protein Coding	3
107	TSR1	TSR1 Ribosome Maturation Factor	Protein Coding	3
108	WDR12	WD Repeat Domain 12	Protein Coding	3
109	RIOK2	RIO Kinase 2	Protein Coding	3
110	EXOSC5	Exosome Component 5	Protein Coding	3
111	WDR18	WD Repeat Domain 18	Protein Coding	3
112	RPL3	Ribosomal Protein L3	Protein Coding	3
113	RPL3L	Ribosomal Protein L3 Like	Protein Coding	3
114	RPL4	Ribosomal Protein L4	Protein Coding	3
115	RPL5	Ribosomal Protein L5	Protein Coding	3
116	RPL6	Ribosomal Protein L6	Protein Coding	3
117	RPL7	Ribosomal Protein L7	Protein Coding	3
118	RPL7A	Ribosomal Protein L7a	Protein Coding	3
119	RPL8	Ribosomal Protein L8	Protein Coding	3
120	RPL9	Ribosomal Protein L9	Protein Coding	3
121	RPL10	Ribosomal Protein L10	Protein Coding	3
122	RPL11	Ribosomal Protein L11	Protein Coding	3
123	RPL12	Ribosomal Protein L12	Protein Coding	3
124	RPL13	Ribosomal Protein L13	Protein Coding	3
125	RPL15	Ribosomal Protein L15	Protein Coding	3
126	RPL17	Ribosomal Protein L17	Protein Coding	3
127	RPL18	Ribosomal Protein L18	Protein Coding	3
128	RPL18A	Ribosomal Protein L18a	Protein Coding	3
129	RPL19	Ribosomal Protein L19	Protein Coding	3
130	RPL21	Ribosomal Protein L21	Protein Coding	3
131	RPL22	Ribosomal Protein L22	Protein Coding	3
132	RPL23A	Ribosomal Protein L23a	Protein Coding	3
133	RPL24	Ribosomal Protein L24	Protein Coding	3
134	RPL26	Ribosomal Protein L26	Protein Coding	3
135	RPL27	Ribosomal Protein L27	Protein Coding	3
136	RPL30	Ribosomal Protein L30	Protein Coding	3
137	RPL27A	Ribosomal Protein L27a	Protein Coding	3
138	RPL28	Ribosomal Protein L28	Protein Coding	3
139	RPL29	Ribosomal Protein L29	Protein Coding	3
140	RPL31	Ribosomal Protein L31	Protein Coding	3
141	RPL32	Ribosomal Protein L32	Protein Coding	3
142	RPL34	Ribosomal Protein L34	Protein Coding	3
143	RPL35A	Ribosomal Protein L35a	Protein Coding	3
144	RPL36AL	Ribosomal Protein L36a Like	Protein Coding	3
145	RPL37	Ribosomal Protein L37	Protein Coding	3
146	RPL37A	Ribosomal Protein L37a	Protein Coding	3
147	RPL38	Ribosomal Protein L38	Protein Coding	3
148	RPL39	Ribosomal Protein L39	Protein Coding	3
149	RPL41	Ribosomal Protein L41	Protein Coding	3
150	RPL36A	Ribosomal Protein L36a	Protein Coding	3
151	RPLP0	Ribosomal Protein Lateral Stalk Subunit P0	Protein Coding	3
152	RPLP1	Ribosomal Protein Lateral Stalk Subunit P1	Protein Coding	3
153	RPLP2	Ribosomal Protein Lateral Stalk Subunit P2	Protein Coding	3
154	RPS3	Ribosomal Protein S3	Protein Coding	3
155	RPS3A	Ribosomal Protein S3A	Protein Coding	3
156	RPS4X	Ribosomal Protein S4 X-Linked	Protein Coding	3
157	RPS4Y1	Ribosomal Protein S4 Y-Linked 1	Protein Coding	3
158	RPS5	Ribosomal Protein S5	Protein Coding	3
159	RPS8	Ribosomal Protein S8	Protein Coding	3
160	RPS10	Ribosomal Protein S10	Protein Coding	3
161	RPS11	Ribosomal Protein S11	Protein Coding	3
162	RPS12	Ribosomal Protein S12	Protein Coding	3
163	RPS13	Ribosomal Protein S13	Protein Coding	3
164	RPS15	Ribosomal Protein S15	Protein Coding	3
165	RPS15A	Ribosomal Protein S15a	Protein Coding	3
166	RPS16	Ribosomal Protein S16	Protein Coding	3
167	RPS17	Ribosomal Protein S17	Protein Coding	3
168	RPS18	Ribosomal Protein S18	Protein Coding	3
169	RPS19	Ribosomal Protein S19	Protein Coding	3
170	RPS20	Ribosomal Protein S20	Protein Coding	3
171	RPS21	Ribosomal Protein S21	Protein Coding	3
172	RPS23	Ribosomal Protein S23	Protein Coding	3
173	RPS24	Ribosomal Protein S24	Protein Coding	3
174	RPS25	Ribosomal Protein S25	Protein Coding	3
175	RPS26	Ribosomal Protein S26	Protein Coding	3
176	RPS27	Ribosomal Protein S27	Protein Coding	3
177	RPS27A	Ribosomal Protein S27a	Protein Coding	3
178	RPS28	Ribosomal Protein S28	Protein Coding	3
179	RPS29	Ribosomal Protein S29	Protein Coding	3
180	BYSL	Bystin Like	Protein Coding	3
181	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	3
182	NOL12	Nucleolar Protein 12	Protein Coding	3
183	NOL9	Nucleolar Protein 9	Protein Coding	3
184	RPP21	Ribonuclease P Subunit P21	Protein Coding	3
185	ISG20L2	Interferon Stimulated Exonuclease Gene 20 Like 2	Protein Coding	3
186	LAS1L	LAS1 Like Ribosome Biogenesis Factor	Protein Coding	3
187	RIOK1	RIO Kinase 1	Protein Coding	3
188	LTV1	LTV1 Ribosome Biogenesis Factor	Protein Coding	3
189	RRP1	Ribosomal RNA Processing 1	Protein Coding	3
190	RIOK3	RIO Kinase 3	Protein Coding	3
191	RPL14	Ribosomal Protein L14	Protein Coding	3
192	ERI1	Exoribonuclease 1	Protein Coding	3
193	DDX21	DExD-Box Helicase 21	Protein Coding	3
194	RPL23	Ribosomal Protein L23	Protein Coding	3
195	MTERF4	Mitochondrial Transcription Termination Factor 4	Protein Coding	1
196	FASTKD2	FAST Kinase Domains 2	Protein Coding	1
197	TRUB2	TruB Pseudouridine Synthase Family Member 2	Protein Coding	1
198	RPUSD3	RNA Pseudouridine Synthase D3	Protein Coding	1
199	MRM2	Mitochondrial RRNA Methyltransferase 2	Protein Coding	1
200	HSD17B10	Hydroxysteroid 17-Beta Dehydrogenase 10	Protein Coding	1
201	NSUN4	NOP2/Sun RNA Methyltransferase 4	Protein Coding	1
202	MTERF3	Mitochondrial Transcription Termination Factor 3	Protein Coding	1
203	TFB1M	Transcription Factor B1, Mitochondrial	Protein Coding	1
204	NGRN	Neugrin, Neurite Outgrowth Associated	Protein Coding	1
205	TRMT10C	TRNA Methyltransferase 10C, Mitochondrial RNase P Subunit	Protein Coding	1
206	MRM3	Mitochondrial RRNA Methyltransferase 3	Protein Coding	1
207	ELAC2	ElaC Ribonuclease Z 2	Protein Coding	1
208	MRM1	Mitochondrial RRNA Methyltransferase 1	Protein Coding	1
209	RCC1L	RCC1 Like	Protein Coding	1
210	RPUSD4	RNA Pseudouridine Synthase D4	Protein Coding	1
211	PRORP	Protein Only RNase P Catalytic Subunit	Protein Coding	1

Disorders associated with rRNA processing in the nucleus and cytosol SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Diamond-blackfan anemia	Enrichment	RPL11, RPL15, RPL17, RPL18, RPL26, RPL27, RPL31, RPL35, RPL35A, RPL5, RPL8, RPL9, RPS10, RPS15A, RPS17, RPS19, RPS20, RPS24, RPS26, RPS27, RPS28, RPS29, RPS7	16.00
2	Diamond-blackfan anemia 1	Enrichment	RPL11, RPL17, RPL35A, RPL5, RPL9, RPS10, RPS17, RPS19, RPS20, RPS24, RPS26, RPS7	10.93
3	Pontocerebellar hypoplasia, type 1e	Enrichment	EXOSC3, EXOSC8, EXOSC9	4.32
4	Dyskeratosis congenita	Enrichment	DKC1, NHP2, NOP10	4.10
5	Diamond-blackfan anemia 15 with mandibulofacial dysostosis	Enrichment	RPS26, RPS28	3.26
6	North american indian childhood cirrhosis	Enrichment	UTP4	2.35
7	Glaucoma 1, open angle, g	Enrichment	WDR36	2.35
8	Dyskeratosis congenita, autosomal recessive 1	Enrichment	NOP10	2.35
9	Bowen-conradi syndrome	Enrichment	EMG1	2.35
10	46,xy sex reversal 11	Enrichment	DHX37	2.35
11	Cataracts, hearing impairment, nephrotic syndrome, and enterocolitis 2	Enrichment	NOP10	2.35
12	Cataracts, hearing impairment, nephrotic syndrome, and enterocolitis 1	Enrichment	DKC1	2.35
13	Diamond-blackfan anemia 8	Enrichment	RPS7	2.35
14	Microcephaly 28, primary, autosomal recessive	Enrichment	RRP7A	2.35
15	Neurodevelopmental disorder with brain anomalies and with or without vertebral or cardiac anomalies	Enrichment	DHX37	2.35
16	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 9	Enrichment	NOP10	2.35
17	Chromosome 5q deletion syndrome	Enrichment	RPS14	2.05
18	Dyskeratosis congenita, autosomal recessive 2	Enrichment	NHP2	2.05
19	Neurodevelopmental disorder with speech delay and variable ocular anomalies	Enrichment	THUMPD1	2.05
20	Psychotic disorder	Enrichment	RCL1	2.05
21	Protein-deficiency anemia	Enrichment	RPL11, RPS26	1.89
22	Aplasia cutis congenita, nonsyndromic	Enrichment	BMS1	1.87
23	Dyskeratosis congenita, x-linked	Enrichment	DKC1	1.87
24	Congenital disorder of glycosylation, type ip	Enrichment	UTP14C	1.87
25	Spinocerebellar ataxia 36	Enrichment	NOP56	1.87
26	Intellectual developmental disorder, x-linked, syndromic 35	Enrichment	RPL10	1.87
27	Asplenia, isolated congenital	Enrichment	RPSA	1.87
28	Intellectual developmental disorder, x-linked, syndromic, wilson-turner type	Enrichment	LAS1L	1.87
29	Diamond-blackfan anemia 10	Enrichment	RPS26	1.87
30	Alopecia, neurologic defects, and endocrinopathy syndrome	Enrichment	RBM28	1.87
31	Hypotrichosis 12	Enrichment	RPL21	1.87
32	Diamond-blackfan anemia 13	Enrichment	RPS29	1.87
33	Advanced sleep phase syndrome, familial, 2	Enrichment	CSNK1D	1.87
34	Diamond-blackfan anemia 7	Enrichment	RPL11	1.87
35	Diamond-blackfan anemia 18	Enrichment	RPL18	1.87
36	Spondyloepimetaphyseal dysplasia, isidor-toutain type	Enrichment	RPL13	1.87
37	Spermatogenic failure 63	Enrichment	RPL10L	1.87
38	Pontocerebellar hypoplasia, type 1f	Enrichment	EXOSC1	1.87
39	Autism x-linked 5	Enrichment	RPL10	1.87
40	Cerebellar ataxia, brain abnormalities, and cardiac conduction defects	Enrichment	EXOSC5	1.87
41	Diamond-blackfan anemia 20	Enrichment	RPS15A	1.87
42	Hoxha-aliu syndrome	Enrichment	ERI1	1.87
43	Diamond-blackfan anemia 3	Enrichment	RPS24	1.87
44	Diamond-blackfan anemia 4	Enrichment	RPS17	1.87
45	Diamond-blackfan anemia 11	Enrichment	RPL26	1.87
46	Pontocerebellar hypoplasia, type 1c	Enrichment	EXOSC8	1.87
47	Inflammatory poikiloderma with hair abnormalities and acral keratoses	Enrichment	LTV1	1.87
48	Spondyloepimetaphyseal dysplasia	Enrichment	RPL13	1.87
49	Pontocerebellar hypoplasia, type 1d	Enrichment	EXOSC9	1.87
50	Diamond-blackfan anemia 19	Enrichment	RPL35	1.87
51	Short stature, hearing loss, retinitis pigmentosa, and distinctive facies	Enrichment	EXOSC2	1.87
52	Brachycephaly, trichomegaly, and developmental delay	Enrichment	RPS23	1.87
53	Cardiomyopathy, dilated, 2d	Enrichment	RPL3L	1.87
54	Spinal muscular atrophy with respiratory distress type 2	Enrichment	LAS1L	1.87
55	X-linked intellectual disability-cerebellar hypoplasia-spondylo-epiphyseal dysplasia syndrome	Enrichment	RPL10	1.87
56	Spondyloepimetaphyseal dysplasia, guo-campeau type	Enrichment	ERI1	1.87
57	Pure red-cell aplasia	Enrichment	RPS26	1.87
58	Diamond-blackfan anemia 22	Enrichment	RPL17	1.87
59	X-linked microcephaly-growth retardation-prognathism-cryptorchidism syndrome	Enrichment	RPL10	1.87
60	Hsd10 mitochondrial disease	Enrichment	HSD17B10	1.81
61	Combined oxidative phosphorylation deficiency 30	Enrichment	TRMT10C	1.81
62	Syndromic x-linked intellectual disability type 10	Enrichment	HSD17B10	1.81
63	Prostate cancer, hereditary, 2	Enrichment	ELAC2	1.81
64	Combined oxidative phosphorylation deficiency 17	Enrichment	ELAC2	1.81
65	Mitochondrial dna depletion syndrome 17	Enrichment	MRM2	1.81
66	Fastkd2-related infantile mitochondrial encephalomyopathy	Enrichment	FASTKD2	1.81
67	Aplasia cutis congenita	Enrichment	BMS1	1.65
68	Pontocerebellar hypoplasia	Enrichment	EXOSC3, EXOSC9	1.61
69	Coloboma of optic nerve	Enrichment	DHX37	1.57
70	Hoyeraal-hreidarsson syndrome	Enrichment	DKC1	1.57
71	Diamond-blackfan anemia 6	Enrichment	RPL5	1.57
72	Diamond-blackfan anemia 9	Enrichment	RPS10	1.57
73	Diamond-blackfan anemia 5	Enrichment	RPL35A	1.57
74	Diamond-blackfan anemia 12	Enrichment	RPL15	1.57
75	Wilson-turner syndrome	Enrichment	LAS1L	1.57
76	Diamond-blackfan anemia 16	Enrichment	RPL27	1.57
77	Diamond-blackfan anemia 17	Enrichment	RPS27	1.57
78	Congenital pontocerebellar hypoplasia type 1	Enrichment	EXOSC3	1.57
79	Familial isolated congenital asplenia	Enrichment	RPSA	1.57
80	Combined oxidative phosphorylation deficiency 54	Enrichment	PRORP	1.51
81	Combined oxidative phosphorylation deficiency 44	Enrichment	FASTKD2	1.51
82	Spastic ataxia 10, autosomal recessive	Enrichment	TRUB2	1.51
83	Pontocerebellar hypoplasia, type 1b	Enrichment	EXOSC3	1.40
84	Cerebellar disease	Enrichment	EXOSC3	1.40
85	Macrocytic anemia	Enrichment	RPL17	1.40
86	Advanced sleep phase syndrome	Enrichment	CSNK1D	1.40
87	Polymicrogyria	Enrichment	DHX37	1.36
88	Coenzyme q10 deficiency, primary, 7	Enrichment	TRUB2	1.34
89	46,xy complete gonadal dysgenesis	Enrichment	DHX37	1.32
90	46,xy partial gonadal dysgenesis	Enrichment	DHX37	1.21
91	Male infertility with spermatogenesis disorder	Enrichment	DHX37	1.18
92	Hemangioma	Enrichment	RPL5	1.18
93	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	DKC1	1.16
94	Pancytopenia	Enrichment	RPL17	1.10
95	Williams-beuren syndrome	Enrichment	BUD23	1.06
96	Hypotrichosis simplex	Enrichment	RPL21	0.94
97	Leukemia, chronic lymphocytic	Enrichment	RPS15	0.89
98	Aplastic anemia	Enrichment	RPL5	0.89
99	Perrault syndrome 2	Enrichment	PRORP	0.88
100	Atrial heart septal defect	Enrichment	RPL5	0.86
101	Interatrial communication	Enrichment	RPL5	0.86
102	Familial colorectal cancer type x	Enrichment	RPS20	0.86
103	Rare mitochondrial non-syndromic sensorineural deafness	Enrichment	TFB1M	0.84
104	Epicanthus	Enrichment	RPL17	0.82
105	Renal hypodysplasia/aplasia 3	Enrichment	ERI1	0.82
106	Pulmonary hypertension, primary, 1	Enrichment	RPL5	0.79
107	Lactic acidosis	Enrichment	PRORP	0.77
108	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	DHX37, RPL10L	0.75
109	Perrault syndrome 1	Enrichment	PRORP	0.65
110	Congenital myopathy	Enrichment	EXOSC3	0.64
111	Lissencephaly	Enrichment	EXOSC3	0.60
112	Attention deficit-hyperactivity disorder	Enrichment	RPL17	0.59
113	Developmental and epileptic encephalopathy 1	Enrichment	CSNK1E	0.54
114	Mitochondrial complex iv deficiency, nuclear type 1	Enrichment	FASTKD2	0.53
115	Prostate cancer	Enrichment	ELAC2	0.44
116	Fetal akinesia deformation sequence 1	Enrichment	EXOSC3	0.40
117	West syndrome	Enrichment	CSNK1E	0.34
118	Spastic ataxia	Enrichment	EXOSC8	0.29
119	Familial isolated dilated cardiomyopathy	Enrichment	RPL3L	0.29
120	Myeloma, multiple	Enrichment	DIS3	0.27
121	Microcephaly	Enrichment	EXOSC3, PRORP	0.24
122	Autism	Enrichment	RPL17	0.20
123	Leigh syndrome, nuclear	Enrichment	FASTKD2	0.18
124	Leigh disease	Enrichment	FASTKD2	0.16
125	Mitochondrial disease	Enrichment	TRMT10C	0.13
126	Congenital nervous system abnormality	Enrichment	EXOSC3	0.12
127	Nervous system disease	Enrichment	EXOSC3	0.12
128	Ovarian cancer	Enrichment	ELAC2	0.10
129	Inherited cancer-predisposing syndrome	Enrichment	RPS20	0.08

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

rRNA processing in the nucleus and cytosol

Pathway Network for rRNA processing in the nucleus and cytosol

Pathway network for the rRNA processing in the nucleus and cytosol SuperPath

Member Pathways for rRNA processing in the nucleus and cytosol

Pathways in the rRNA processing in the nucleus and cytosol SuperPath

Gene overlap in member pathways for rRNA processing in the nucleus and cytosol SuperPath

Associated Genes for rRNA processing in the nucleus and cytosol

Associated Disorders for rRNA processing in the nucleus and cytosol

Disorders associated with rRNA processing in the nucleus and cytosol SuperPath

STRING Interaction Network for rRNA processing in the nucleus and cytosol

Sources for rRNA processing in the nucleus and cytosol