RUNX1 regulates expression of components of tight junctions

No Pathway Network information available for RUNX1 regulates expression of components of tight junctions

#	Name	Source	Genes
1	RUNX1 regulates expression of components of tight junctions	Reactome	CBFB CLDN5 RUNX1 TJP1

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TJP1	Tight Junction Protein 1	Protein Coding	1
2	CLDN5	Claudin 5	Protein Coding	1
3	RUNX1	RUNX Family Transcription Factor 1	Protein Coding	1
4	CBFB	Core-Binding Factor Subunit Beta	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Storage pool platelet disease	Enrichment	RUNX1	3.23
2	Cleidocranial dysplasia 2	Enrichment	CBFB	3.23
3	Tafro syndrome	Enrichment	RUNX1	3.23
4	Platelet disorder, familial, with associated myeloid malignancy	Enrichment	RUNX1	3.05
5	Hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with runx1	Enrichment	RUNX1	3.05
6	Blood platelet disease	Enrichment	RUNX1	2.93
7	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	CBFB	2.93
8	Aggressive systemic mastocytosis	Enrichment	RUNX1	2.83
9	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	RUNX1	2.83
10	Pancytopenia	Enrichment	RUNX1	2.75
11	Leukemia, chronic myeloid	Enrichment	RUNX1	2.69
12	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	RUNX1	2.58
13	Leukemia, acute myeloid	Enrichment	RUNX1	1.93
14	Thrombocytopenia	Enrichment	RUNX1	1.85
15	Inherited cancer-predisposing syndrome	Enrichment	RUNX1	1.42

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for RUNX1 regulates expression of components of tight junctions