RUNX1 regulates transcription of genes involved in BCR signaling

No Pathway Network information available for RUNX1 regulates transcription of genes involved in BCR signaling

#	Name	Source	Genes
1	RUNX1 regulates transcription of genes involved in BCR signaling	Reactome	BLK CBFB ELF1 ELF2 PAX5 RUNX1 (see all 6) (see less)
2	RUNX1 regulates transcription of genes involved in interleukin signaling	Reactome	CBFB ELF1 IL3 LIFR RUNX1

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ELF1	E74 Like ETS Transcription Factor 1	Protein Coding	2
2	RUNX1	RUNX Family Transcription Factor 1	Protein Coding	2
3	CBFB	Core-Binding Factor Subunit Beta	Protein Coding	2
4	ELF2	E74 Like ETS Transcription Factor 2	Protein Coding	1
5	PAX5	Paired Box 5	Protein Coding	1
6	BLK	BLK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
7	IL3	Interleukin 3	Protein Coding	1
8	LIFR	LIF Receptor Subunit Alpha	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Storage pool platelet disease	Enrichment	RUNX1	3.13
2	Cleidocranial dysplasia 2	Enrichment	CBFB	3.13
3	Tafro syndrome	Enrichment	RUNX1	3.13
4	Maturity-onset diabetes of the young, type 11	Enrichment	BLK	3.05
5	Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome	Enrichment	ELF2	3.05
6	B-lymphoblastic leukemia/lymphoma with t(7;9)(q11.2;p13.2)	Enrichment	PAX5	3.05
7	Platelet disorder, familial, with associated myeloid malignancy	Enrichment	RUNX1	2.96
8	Stuve-wiedemann syndrome 1	Enrichment	LIFR	2.96
9	Hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with runx1	Enrichment	RUNX1	2.96
10	Stüve-wiedemann syndrome	Enrichment	LIFR	2.96
11	Blood platelet disease	Enrichment	RUNX1	2.83
12	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	CBFB	2.83
13	Aggressive systemic mastocytosis	Enrichment	RUNX1	2.73
14	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	RUNX1	2.73
15	Pancytopenia	Enrichment	RUNX1	2.66
16	Leukemia, chronic myeloid	Enrichment	RUNX1	2.59
17	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	RUNX1	2.48
18	Leukemia, acute lymphoblastic 3	Enrichment	PAX5	2.40
19	Leukemia, acute lymphoblastic	Enrichment	PAX5	2.31
20	Maturity-onset diabetes of the young	Enrichment	BLK	2.05
21	Cakut	Enrichment	LIFR	1.90
22	Leukemia, acute myeloid	Enrichment	RUNX1	1.83
23	Systemic lupus erythematosus	Enrichment	BLK	1.77
24	Thrombocytopenia	Enrichment	RUNX1	1.76
25	Inherited cancer-predisposing syndrome	Enrichment	RUNX1	1.32

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for RUNX1 regulates transcription of genes involved in BCR signaling