RUNX1 regulates transcription of genes involved in differentiation of keratinocytes

No Pathway Network information available for RUNX1 regulates transcription of genes involved in differentiation of keratinocytes

#	Name	Source	Genes
1	RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Reactome	CBFB CTSK CTSL CTSV RUNX1 SERPINB13 SOCS3 SOCS4 (see all 8) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SOCS4	Suppressor Of Cytokine Signaling 4	Protein Coding	1
2	CTSK	Cathepsin K	Protein Coding	1
3	CTSL	Cathepsin L	Protein Coding	1
4	CTSV	Cathepsin V	Protein Coding	1
5	SERPINB13	Serpin Family B Member 13	Protein Coding	1
6	RUNX1	RUNX Family Transcription Factor 1	Protein Coding	1
7	CBFB	Core-Binding Factor Subunit Beta	Protein Coding	1
8	SOCS3	Suppressor Of Cytokine Signaling 3	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Pycnodysostosis	Enrichment	CTSK	3.23
2	Dermatitis, atopic, 4	Enrichment	SOCS3	3.23
3	Storage pool platelet disease	Enrichment	RUNX1	2.93
4	Cleidocranial dysplasia 2	Enrichment	CBFB	2.93
5	Tafro syndrome	Enrichment	RUNX1	2.93
6	Platelet disorder, familial, with associated myeloid malignancy	Enrichment	RUNX1	2.75
7	Nail disorder, nonsyndromic congenital, 9	Enrichment	CTSK	2.75
8	Hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with runx1	Enrichment	RUNX1	2.75
9	Blood platelet disease	Enrichment	RUNX1	2.63
10	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	CBFB	2.63
11	Aggressive systemic mastocytosis	Enrichment	RUNX1	2.53
12	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	RUNX1	2.53
13	Pancytopenia	Enrichment	RUNX1	2.45
14	Leukemia, chronic myeloid	Enrichment	RUNX1	2.38
15	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	RUNX1	2.28
16	Primary bone dysplasia	Enrichment	CTSK	2.23
17	Osteochondrodysplasia	Enrichment	CTSK	2.19
18	Scoliosis	Enrichment	CTSK	1.85
19	Leukemia, acute myeloid	Enrichment	RUNX1	1.63
20	Thrombocytopenia	Enrichment	RUNX1	1.55
21	Inherited cancer-predisposing syndrome	Enrichment	RUNX1	1.12

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for RUNX1 regulates transcription of genes involved in differentiation of keratinocytes