RUNX1 regulates transcription of genes involved in differentiation of myeloid cells

No Pathway Network information available for RUNX1 regulates transcription of genes involved in differentiation of myeloid cells

Pathways in the RUNX1 regulates transcription of genes involved in differentiation of myeloid cells SuperPath

#	Name	Source	Genes
1	RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	Reactome	CBFB CREBBP CSF2 LGALS3 PRKCB RUNX1 RUNX2 (see all 7) (see less)
2	RUNX2 regulates genes involved in differentiation of myeloid cells	Reactome	CBFB LGALS3 RUNX1 RUNX2

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	LGALS3	Galectin 3	Protein Coding	2
2	RUNX2	RUNX Family Transcription Factor 2	Protein Coding	2
3	RUNX1	RUNX Family Transcription Factor 1	Protein Coding	2
4	CBFB	Core-Binding Factor Subunit Beta	Protein Coding	2
5	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
6	CSF2	Colony Stimulating Factor 2	Protein Coding	1
7	PRKCB	Protein Kinase C Beta	Protein Coding	1

Disorders associated with RUNX1 regulates transcription of genes involved in differentiation of myeloid cells SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Menke-hennekam syndrome 1	Enrichment	CREBBP	3.29
2	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	3.29
3	Menke-hennekam syndrome	Enrichment	CREBBP	3.29
4	Metaphyseal dysplasia with maxillary hypoplasia with or without brachydactyly	Enrichment	RUNX2	3.23
5	Storage pool platelet disease	Enrichment	RUNX1	3.23
6	Cleidocranial dysplasia 2	Enrichment	CBFB	3.23
7	Tafro syndrome	Enrichment	RUNX1	3.23
8	Cleidocranial dysplasia 1	Enrichment	RUNX2	3.05
9	Platelet disorder, familial, with associated myeloid malignancy	Enrichment	RUNX1	3.05
10	Cleidocranial dysplasia	Enrichment	RUNX2	3.05
11	Hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with runx1	Enrichment	RUNX1	3.05
12	Thumb deformity	Enrichment	CREBBP	2.99
13	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	2.99
14	Blood platelet disease	Enrichment	RUNX1	2.93
15	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	CBFB	2.93
16	Aggressive systemic mastocytosis	Enrichment	RUNX1	2.83
17	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	RUNX1	2.83
18	Tethered spinal cord syndrome	Enrichment	CREBBP	2.81
19	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	2.81
20	Pancytopenia	Enrichment	RUNX1	2.75
21	Leukemia, chronic myeloid	Enrichment	RUNX1	2.69
22	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	RUNX1	2.58
23	Rubinstein-taybi syndrome 1	Enrichment	CREBBP	2.51
24	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP	2.51
25	Hypertrichosis	Enrichment	CREBBP	2.51
26	Heart disease	Enrichment	CREBBP	2.14
27	Corpus callosum, agenesis of	Enrichment	CREBBP	2.11
28	Isolated corpus callosum agenesis	Enrichment	CREBBP	2.11
29	Rare genetic intellectual disability	Enrichment	CREBBP	2.11
30	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP	2.11
31	Diffuse large b-cell lymphoma	Enrichment	CREBBP	2.01
32	Leukemia, acute myeloid	Enrichment	RUNX1	1.93
33	Scoliosis	Enrichment	CREBBP	1.91
34	Nephrotic syndrome	Enrichment	RUNX2	1.90
35	Thrombocytopenia	Enrichment	RUNX1	1.85
36	Myeloma, multiple	Enrichment	CREBBP	1.54
37	Autism	Enrichment	CREBBP	1.44
38	Inherited cancer-predisposing syndrome	Enrichment	RUNX1	1.42
39	Congenital nervous system abnormality	Enrichment	CREBBP	1.27
40	Nervous system disease	Enrichment	CREBBP	1.27

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

RUNX1 regulates transcription of genes involved in differentiation of myeloid cells

Pathway Network for RUNX1 regulates transcription of genes involved in differentiation of myeloid cells

Member Pathways for RUNX1 regulates transcription of genes involved in differentiation of myeloid cells

Pathways in the RUNX1 regulates transcription of genes involved in differentiation of myeloid cells SuperPath

Associated Genes for RUNX1 regulates transcription of genes involved in differentiation of myeloid cells

Associated Disorders for RUNX1 regulates transcription of genes involved in differentiation of myeloid cells

Disorders associated with RUNX1 regulates transcription of genes involved in differentiation of myeloid cells SuperPath

STRING Interaction Network for RUNX1 regulates transcription of genes involved in differentiation of myeloid cells

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