S1P4 pathway
Pathways in the S1P4 pathway SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | S1P4 pathway | PubChem | |
| 2 | S1P5 pathway | PubChem |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | S1PR5 | Sphingosine-1-Phosphate Receptor 5 | Protein Coding | 2 |
| 2 | GNA12 | G Protein Subunit Alpha 12 | Protein Coding | 2 |
| 3 | RHOA | Ras Homolog Family Member A | Protein Coding | 2 |
| 4 | S1PR4 | Sphingosine-1-Phosphate Receptor 4 | Protein Coding | 1 |
| 5 | GNA13 | G Protein Subunit Alpha 13 | Protein Coding | 1 |
| 6 | CDC42 | Cell Division Cycle 42 | Protein Coding | 1 |
| 7 | PLCG1 | Phospholipase C Gamma 1 | Protein Coding | 1 |
| 8 | MAPK3 | Mitogen-Activated Protein Kinase 3 | Protein Coding | 1 |
Disorders associated with S1P4 pathway SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies | Enrichment | RHOA | 3.66 |
| 2 | Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies | Enrichment | RHOA | 3.66 |
| 3 | Immune dysregulation, autoimmunity, and autoinflammation | Enrichment | PLCG1 | 3.23 |
| 4 | Takenouchi-kosaki syndrome | Enrichment | CDC42 | 3.23 |
| 5 | Nocarh syndrome | Enrichment | CDC42 | 3.23 |
| 6 | Immune system disease | Enrichment | CDC42 | 2.93 |
| 7 | Hemihyperplasia, isolated | Enrichment | RHOA | 2.88 |
| 8 | Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia | Enrichment | CDC42 | 2.63 |
