selenocysteine biosynthesis

No Pathway Network information available for selenocysteine biosynthesis

#	Name	Source	Genes
1	selenocysteine biosynthesis	PubChem	PSTK SARS1 SARS2 SEPHS1 SEPHS2 SEPSECS (see all 6) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SEPHS1	Selenophosphate Synthetase 1	Protein Coding	1
2	SARS2	Seryl-TRNA Synthetase 2, Mitochondrial	Protein Coding	1
3	SEPSECS	Sep (O-Phosphoserine) TRNA:Sec (Selenocysteine) TRNA Synthase	Protein Coding	1
4	PSTK	Phosphoseryl-TRNA Kinase	Protein Coding	1
5	SARS1	Seryl-TRNA Synthetase 1	Protein Coding	1
6	SEPHS2	Selenophosphate Synthetase 2	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Neurodevelopmental disorder with microcephaly, ataxia, and seizures	Enrichment	SARS1	3.35
2	Hyperuricemia, pulmonary hypertension, renal failure, and alkalosis syndrome	Enrichment	SARS2	3.35
3	Ververi-brady syndrome 2	Enrichment	SEPHS1	3.35
4	Kyphosis	Enrichment	SEPSECS	2.88
5	Pontocerebellar hypoplasia, type 2d	Enrichment	SEPSECS	2.66
6	Spastic diplegia	Enrichment	SEPSECS	2.66
7	Pontocerebellar hypoplasia, type 2e	Enrichment	SEPSECS	2.51
8	Pontocerebellar hypoplasia	Enrichment	SEPSECS	2.10
9	Arteriovenous malformations of the brain	Enrichment	SARS1	2.08
10	Primary autosomal recessive microcephaly	Enrichment	SARS1	1.85
11	Distal arthrogryposis	Enrichment	SEPSECS	1.73
12	Spastic ataxia	Enrichment	SEPSECS	1.63
13	Autosomal recessive non-syndromic intellectual disability	Enrichment	SARS1	1.60

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for selenocysteine biosynthesis