Separation of Sister Chromatids
Pathways in the Separation of Sister Chromatids SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Separation of Sister Chromatids | Reactome | |
| 2 | Mitotic Metaphase and Anaphase | Reactome | |
| 3 | Mitotic Anaphase | Reactome | |
| 4 | Regulation of sister chromatid separation at the metaphase-anaphase transition | WikiPathways |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | STAG1 | STAG1 Cohesin Complex Component | Protein Coding | 4 |
| 2 | CENPE | Centromere Protein E | Protein Coding | 4 |
| 3 | ANAPC2 | Anaphase Promoting Complex Subunit 2 | Protein Coding | 4 |
| 4 | MAD2L1 | Mitotic Arrest Deficient 2 Like 1 | Protein Coding | 4 |
| 5 | ANAPC11 | Anaphase Promoting Complex Subunit 11 | Protein Coding | 4 |
| 6 | RAD21 | RAD21 Cohesin Complex Component | Protein Coding | 4 |
| 7 | BUB1 | BUB1 Mitotic Checkpoint Serine/Threonine Kinase | Protein Coding | 4 |
| 8 | BUB1B | BUB1 Mitotic Checkpoint Serine/Threonine Kinase B | Protein Coding | 4 |
| 9 | SMC1A | Structural Maintenance Of Chromosomes 1A | Protein Coding | 4 |
| 10 | MAD1L1 | Mitotic Arrest Deficient 1 Like 1 | Protein Coding | 4 |
| 11 | SMC3 | Structural Maintenance Of Chromosomes 3 | Protein Coding | 4 |
| 12 | BUB3 | BUB3 Mitotic Checkpoint Protein | Protein Coding | 4 |
| 13 | PTTG1 | PTTG1 Regulator Of Sister Chromatid Separation, Securin | Protein Coding | 4 |
| 14 | ESPL1 | Extra Spindle Pole Bodies Like 1, Separase | Protein Coding | 4 |
| 15 | CDC20 | Cell Division Cycle 20 | Protein Coding | 4 |
| 16 | CENPS-CORT | CENPS-CORT Readthrough | Protein Coding | 3 |
| 17 | PMF1-BGLAP | PMF1-BGLAP Readthrough | Protein Coding | 3 |
| 18 | PSMD14 | Proteasome 26S Subunit, Non-ATPase 14 | Protein Coding | 3 |
| 19 | TUBA1B | Tubulin Alpha 1b | Protein Coding | 3 |
| 20 | TUBB3 | Tubulin Beta 3 Class III | Protein Coding | 3 |
| 21 | TUBB4A | Tubulin Beta 4A Class IVa | Protein Coding | 3 |
| 22 | TUBB4B | Tubulin Beta 4B Class IVb | Protein Coding | 3 |
| 23 | ANAPC10 | Anaphase Promoting Complex Subunit 10 | Protein Coding | 3 |
| 24 | NDC80 | NDC80 Kinetochore Complex Component | Protein Coding | 3 |
| 25 | CENPA | Centromere Protein A | Protein Coding | 3 |
| 26 | CENPC | Centromere Protein C | Protein Coding | 3 |
| 27 | CENPF | Centromere Protein F | Protein Coding | 3 |
| 28 | NUDC | Nuclear Distribution C, Dynein Complex Regulator | Protein Coding | 3 |
| 29 | STAG2 | STAG2 Cohesin Complex Component | Protein Coding | 3 |
| 30 | KIF2C | Kinesin Family Member 2C | Protein Coding | 3 |
| 31 | ADRM1 | ADRM1 26S Proteasome Ubiquitin Receptor | Protein Coding | 3 |
| 32 | UBE2C | Ubiquitin Conjugating Enzyme E2 C | Protein Coding | 3 |
| 33 | ZWINT | ZW10 Interacting Kinetochore Protein | Protein Coding | 3 |
| 34 | PMF1 | Polyamine Modulated Factor 1 | Protein Coding | 3 |
| 35 | TUBA3E | Tubulin Alpha 3e | Protein Coding | 3 |
| 36 | CDCA5 | Cell Division Cycle Associated 5 | Protein Coding | 3 |
| 37 | TUBA3D | Tubulin Alpha 3d | Protein Coding | 3 |
| 38 | ANAPC16 | Anaphase Promoting Complex Subunit 16 | Protein Coding | 3 |
| 39 | DYNLL2 | Dynein Light Chain LC8-Type 2 | Protein Coding | 3 |
| 40 | SPC24 | SPC24 Component Of NDC80 Kinetochore Complex | Protein Coding | 3 |
| 41 | SGO2 | Shugoshin 2 | Protein Coding | 3 |
| 42 | SGO1 | Shugoshin 1 | Protein Coding | 3 |
| 43 | DYNC1H1 | Dynein Cytoplasmic 1 Heavy Chain 1 | Protein Coding | 3 |
| 44 | DYNC1I1 | Dynein Cytoplasmic 1 Intermediate Chain 1 | Protein Coding | 3 |
| 45 | DYNC1I2 | Dynein Cytoplasmic 1 Intermediate Chain 2 | Protein Coding | 3 |
| 46 | DYNC1LI2 | Dynein Cytoplasmic 1 Light Intermediate Chain 2 | Protein Coding | 3 |
| 47 | SKA1 | Spindle And Kinetochore Associated Complex Subunit 1 | Protein Coding | 3 |
| 48 | MAPRE1 | Microtubule Associated Protein RP/EB Family Member 1 | Protein Coding | 3 |
| 49 | PDS5B | PDS5 Cohesin Associated Factor B | Protein Coding | 3 |
| 50 | WAPL | WAPL Cohesin Release Factor | Protein Coding | 3 |
| 51 | CLASP2 | Cytoplasmic Linker Associated Protein 2 | Protein Coding | 3 |
| 52 | PDS5A | PDS5 Cohesin Associated Factor A | Protein Coding | 3 |
| 53 | NUP160 | Nucleoporin 160 | Protein Coding | 3 |
| 54 | CLASP1 | Cytoplasmic Linker Associated Protein 1 | Protein Coding | 3 |
| 55 | ITGB3BP | Integrin Subunit Beta 3 Binding Protein | Protein Coding | 3 |
| 56 | CDC26 | Cell Division Cycle 26 | Protein Coding | 3 |
| 57 | CENPI | Centromere Protein I | Protein Coding | 3 |
| 58 | ANAPC15 | Anaphase Promoting Complex Subunit 15 | Protein Coding | 3 |
| 59 | AHCTF1 | AT-Hook Containing Transcription Factor 1 | Protein Coding | 3 |
| 60 | NSL1 | NSL1 Component Of MIS12 Kinetochore Complex | Protein Coding | 3 |
| 61 | TUBB8B | Tubulin Beta 8B | Protein Coding | 3 |
| 62 | UBE2S | Ubiquitin Conjugating Enzyme E2 S | Protein Coding | 3 |
| 63 | ANAPC4 | Anaphase Promoting Complex Subunit 4 | Protein Coding | 3 |
| 64 | BIRC5 | Baculoviral IAP Repeat Containing 5 | Protein Coding | 3 |
| 65 | TUBB8 | Tubulin Beta 8 Class VIII | Protein Coding | 3 |
| 66 | TUBB2B | Tubulin Beta 2B Class IIb | Protein Coding | 3 |
| 67 | SKA2 | Spindle And Kinetochore Associated Complex Subunit 2 | Protein Coding | 3 |
| 68 | NUP43 | Nucleoporin 43 | Protein Coding | 3 |
| 69 | INCENP | Inner Centromere Protein | Protein Coding | 3 |
| 70 | CENPS | Centromere Protein S | Protein Coding | 3 |
| 71 | KIF2A | Kinesin Family Member 2A | Protein Coding | 3 |
| 72 | CENPP | Centromere Protein P | Protein Coding | 3 |
| 73 | NUP98 | Nucleoporin 98 And 96 Precursor | Protein Coding | 3 |
| 74 | PAFAH1B1 | Platelet Activating Factor Acetylhydrolase 1b Regulatory Subunit 1 | Protein Coding | 3 |
| 75 | DYNC1LI1 | Dynein Cytoplasmic 1 Light Intermediate Chain 1 | Protein Coding | 3 |
| 76 | ANAPC5 | Anaphase Promoting Complex Subunit 5 | Protein Coding | 3 |
| 77 | ANAPC7 | Anaphase Promoting Complex Subunit 7 | Protein Coding | 3 |
| 78 | TUBA8 | Tubulin Alpha 8 | Protein Coding | 3 |
| 79 | PLK1 | Polo Like Kinase 1 | Protein Coding | 3 |
| 80 | NDE1 | NudE Neurodevelopment Protein 1 | Protein Coding | 3 |
| 81 | ERCC6L | ERCC Excision Repair 6 Like, Spindle Assembly Checkpoint Helicase | Protein Coding | 3 |
| 82 | SPDL1 | Spindle Apparatus Coiled-Coil Protein 1 | Protein Coding | 3 |
| 83 | PPP1CC | Protein Phosphatase 1 Catalytic Subunit Gamma | Protein Coding | 3 |
| 84 | ZWILCH | Zwilch Kinetochore Protein | Protein Coding | 3 |
| 85 | CDCA8 | Cell Division Cycle Associated 8 | Protein Coding | 3 |
| 86 | PPP2CA | Protein Phosphatase 2 Catalytic Subunit Alpha | Protein Coding | 3 |
| 87 | PPP2CB | Protein Phosphatase 2 Catalytic Subunit Beta | Protein Coding | 3 |
| 88 | CENPQ | Centromere Protein Q | Protein Coding | 3 |
| 89 | PPP2R1A | Protein Phosphatase 2 Scaffold Subunit Aalpha | Protein Coding | 3 |
| 90 | PPP2R1B | Protein Phosphatase 2 Scaffold Subunit Abeta | Protein Coding | 3 |
| 91 | PPP2R5A | Protein Phosphatase 2 Regulatory Subunit B''Alpha | Protein Coding | 3 |
| 92 | PPP2R5B | Protein Phosphatase 2 Regulatory Subunit B''Beta | Protein Coding | 3 |
| 93 | PPP2R5C | Protein Phosphatase 2 Regulatory Subunit B''Gamma | Protein Coding | 3 |
| 94 | PPP2R5D | Protein Phosphatase 2 Regulatory Subunit B''Delta | Protein Coding | 3 |
| 95 | PPP2R5E | Protein Phosphatase 2 Regulatory Subunit B''Epsilon | Protein Coding | 3 |
| 96 | NUP133 | Nucleoporin 133 | Protein Coding | 3 |
| 97 | CENPN | Centromere Protein N | Protein Coding | 3 |
| 98 | HDAC8 | Histone Deacetylase 8 | Protein Coding | 3 |
| 99 | RCC2 | Regulator Of Chromosome Condensation 2 | Protein Coding | 3 |
| 100 | PSMA1 | Proteasome 20S Subunit Alpha 1 | Protein Coding | 3 |
| 101 | PSMA2 | Proteasome 20S Subunit Alpha 2 | Protein Coding | 3 |
| 102 | PSMA3 | Proteasome 20S Subunit Alpha 3 | Protein Coding | 3 |
| 103 | PSMA4 | Proteasome 20S Subunit Alpha 4 | Protein Coding | 3 |
| 104 | PSMA5 | Proteasome 20S Subunit Alpha 5 | Protein Coding | 3 |
| 105 | PSMA6 | Proteasome 20S Subunit Alpha 6 | Protein Coding | 3 |
| 106 | PSMA7 | Proteasome 20S Subunit Alpha 7 | Protein Coding | 3 |
| 107 | PSMB1 | Proteasome 20S Subunit Beta 1 | Protein Coding | 3 |
| 108 | PSMB2 | Proteasome 20S Subunit Beta 2 | Protein Coding | 3 |
| 109 | PSMB3 | Proteasome 20S Subunit Beta 3 | Protein Coding | 3 |
| 110 | PSMB4 | Proteasome 20S Subunit Beta 4 | Protein Coding | 3 |
| 111 | PSMB5 | Proteasome 20S Subunit Beta 5 | Protein Coding | 3 |
| 112 | PSMB6 | Proteasome 20S Subunit Beta 6 | Protein Coding | 3 |
| 113 | PSMB7 | Proteasome 20S Subunit Beta 7 | Protein Coding | 3 |
| 114 | PSMC1 | Proteasome 26S Subunit, ATPase 1 | Protein Coding | 3 |
| 115 | PSMC2 | Proteasome 26S Subunit, ATPase 2 | Protein Coding | 3 |
| 116 | PSMC3 | Proteasome 26S Subunit, ATPase 3 | Protein Coding | 3 |
| 117 | PSMC4 | Proteasome 26S Subunit, ATPase 4 | Protein Coding | 3 |
| 118 | PSMC5 | Proteasome 26S Subunit, ATPase 5 | Protein Coding | 3 |
| 119 | PSMC6 | Proteasome 26S Subunit, ATPase 6 | Protein Coding | 3 |
| 120 | PSMD1 | Proteasome 26S Subunit, Non-ATPase 1 | Protein Coding | 3 |
| 121 | PSMD2 | Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 2 | Protein Coding | 3 |
| 122 | KNL1 | Kinetochore Scaffold 1 | Protein Coding | 3 |
| 123 | PSMD3 | Proteasome 26S Subunit, Non-ATPase 3 | Protein Coding | 3 |
| 124 | NUP107 | Nucleoporin 107 | Protein Coding | 3 |
| 125 | PSMD7 | Proteasome 26S Subunit, Non-ATPase 7 | Protein Coding | 3 |
| 126 | PSMD8 | Proteasome 26S Subunit, Non-ATPase 8 | Protein Coding | 3 |
| 127 | PSMD11 | Proteasome 26S Subunit, Non-ATPase 11 | Protein Coding | 3 |
| 128 | PSMD12 | Proteasome 26S Subunit, Non-ATPase 12 | Protein Coding | 3 |
| 129 | PSMD13 | Proteasome 26S Subunit, Non-ATPase 13 | Protein Coding | 3 |
| 130 | SPC25 | SPC25 Component Of NDC80 Kinetochore Complex | Protein Coding | 3 |
| 131 | TAOK1 | TAO Kinase 1 | Protein Coding | 3 |
| 132 | RANBP2 | RAN Binding Protein 2 | Protein Coding | 3 |
| 133 | RANGAP1 | Ran GTPase Activating Protein 1 | Protein Coding | 3 |
| 134 | RPS27 | Ribosomal Protein S27 | Protein Coding | 3 |
| 135 | RPS27A | Ribosomal Protein S27a | Protein Coding | 3 |
| 136 | CLIP1 | CAP-Gly Domain Containing Linker Protein 1 | Protein Coding | 3 |
| 137 | SEC13 | SEC13 Homolog, Nuclear Pore And COPII Component | Protein Coding | 3 |
| 138 | CENPK | Centromere Protein K | Protein Coding | 3 |
| 139 | ANAPC1 | Anaphase Promoting Complex Subunit 1 | Protein Coding | 3 |
| 140 | CENPH | Centromere Protein H | Protein Coding | 3 |
| 141 | TUBA4A | Tubulin Alpha 4a | Protein Coding | 3 |
| 142 | TUBA3C | Tubulin Alpha 3c | Protein Coding | 3 |
| 143 | TUBB2A | Tubulin Beta 2A Class IIa | Protein Coding | 3 |
| 144 | UBA52 | Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 | Protein Coding | 3 |
| 145 | UBB | Ubiquitin B | Protein Coding | 3 |
| 146 | UBC | Ubiquitin C | Protein Coding | 3 |
| 147 | UBE2D1 | Ubiquitin Conjugating Enzyme E2 D1 | Protein Coding | 3 |
| 148 | UBE2E1 | Ubiquitin Conjugating Enzyme E2 E1 | Protein Coding | 3 |
| 149 | XPO1 | Exportin 1 | Protein Coding | 3 |
| 150 | TUBA1A | Tubulin Alpha 1a | Protein Coding | 3 |
| 151 | MIS12 | MIS12 Kinetochore Complex Component | Protein Coding | 3 |
| 152 | CENPM | Centromere Protein M | Protein Coding | 3 |
| 153 | NUP37 | Nucleoporin 37 | Protein Coding | 3 |
| 154 | CENPO | Centromere Protein O | Protein Coding | 3 |
| 155 | CENPU | Centromere Protein U | Protein Coding | 3 |
| 156 | SEM1 | SEM1 26S Proteasome Subunit | Protein Coding | 3 |
| 157 | TUBAL3 | Tubulin Alpha Like 3 | Protein Coding | 3 |
| 158 | NUP85 | Nucleoporin 85 | Protein Coding | 3 |
| 159 | DSN1 | DSN1 Component Of MIS12 Kinetochore Complex | Protein Coding | 3 |
| 160 | TUBA4B | Tubulin Alpha 4b | Protein Coding | 3 |
| 161 | CENPT | Centromere Protein T | Protein Coding | 3 |
| 162 | B9D2 | B9 Domain Containing 2 | Protein Coding | 3 |
| 163 | TUBB1 | Tubulin Beta 1 Class VI | Protein Coding | 3 |
| 164 | NDEL1 | NudE Neurodevelopment Protein 1 Like 1 | Protein Coding | 3 |
| 165 | SEH1L | SEH1 Like Nucleoporin | Protein Coding | 3 |
| 166 | KIF18A | Kinesin Family Member 18A | Protein Coding | 3 |
| 167 | NUF2 | NUF2 Component Of NDC80 Kinetochore Complex | Protein Coding | 3 |
| 168 | TUBB6 | Tubulin Beta 6 Class V | Protein Coding | 3 |
| 169 | KIF2B | Kinesin Family Member 2B | Protein Coding | 3 |
| 170 | TUBA1C | Tubulin Alpha 1c | Protein Coding | 3 |
| 171 | DYNLL1 | Dynein Light Chain LC8-Type 1 | Protein Coding | 3 |
| 172 | CDC23 | Cell Division Cycle 23 | Protein Coding | 3 |
| 173 | CDC16 | Cell Division Cycle 16 | Protein Coding | 3 |
| 174 | CENPL | Centromere Protein L | Protein Coding | 3 |
| 175 | ZW10 | Zw10 Kinetochore Protein | Protein Coding | 3 |
| 176 | AURKB | Aurora Kinase B | Protein Coding | 3 |
| 177 | KNTC1 | Kinetochore Associated 1 | Protein Coding | 3 |
| 178 | CKAP5 | Cytoskeleton Associated Protein 5 | Protein Coding | 3 |
| 179 | PSMD6 | Proteasome 26S Subunit, Non-ATPase 6 | Protein Coding | 3 |
| 180 | CDC27 | Cell Division Cycle 27 | Protein Coding | 3 |
| 181 | RNF103-CHMP3 | RNF103-CHMP3 Readthrough | Protein Coding | 2 |
| 182 | RCC1 | Regulator Of Chromosome Condensation 1 | Protein Coding | 2 |
| 183 | CHMP4B | Charged Multivesicular Body Protein 4B | Protein Coding | 2 |
| 184 | NUP35 | Nucleoporin 35 | Protein Coding | 2 |
| 185 | CC2D1B | Coiled-Coil And C2 Domain Containing 1B | Protein Coding | 2 |
| 186 | EMD | Emerin | Protein Coding | 2 |
| 187 | LEMD2 | LEM Domain Nuclear Envelope Protein 2 | Protein Coding | 2 |
| 188 | SIRT2 | Sirtuin 2 | Protein Coding | 2 |
| 189 | ANKLE2 | Ankyrin Repeat And LEM Domain Containing 2 | Protein Coding | 2 |
| 190 | NUP205 | Nucleoporin 205 | Protein Coding | 2 |
| 191 | NUP188 | Nucleoporin 188 | Protein Coding | 2 |
| 192 | LEMD3 | LEM Domain Containing 3 | Protein Coding | 2 |
| 193 | NUP62 | Nucleoporin 62 | Protein Coding | 2 |
| 194 | CHMP2B | Charged Multivesicular Body Protein 2B | Protein Coding | 2 |
| 195 | VPS4A | Vacuolar Protein Sorting 4 Homolog A | Protein Coding | 2 |
| 196 | CHMP2A | Charged Multivesicular Body Protein 2A | Protein Coding | 2 |
| 197 | CHMP4A | Charged Multivesicular Body Protein 4A | Protein Coding | 2 |
| 198 | KPNB1 | Karyopherin Subunit Beta 1 | Protein Coding | 2 |
| 199 | TNPO1 | Transportin 1 | Protein Coding | 2 |
| 200 | LBR | Lamin B Receptor | Protein Coding | 2 |
| 201 | LMNA | Lamin A/C | Protein Coding | 2 |
| 202 | LMNB1 | Lamin B1 | Protein Coding | 2 |
| 203 | CHMP3 | Charged Multivesicular Body Protein 3 | Protein Coding | 2 |
| 204 | NUP54 | Nucleoporin 54 | Protein Coding | 2 |
| 205 | PPP2R2A | Protein Phosphatase 2 Regulatory Subunit Balpha | Protein Coding | 2 |
| 206 | NDC1 | NDC1 Transmembrane Nucleoporin | Protein Coding | 2 |
| 207 | RAN | RAN, Member RAS Oncogene Family | Protein Coding | 2 |
| 208 | SPAST | Spastin | Protein Coding | 2 |
| 209 | TMPO | Thymopoietin | Protein Coding | 2 |
| 210 | UBE2I | Ubiquitin Conjugating Enzyme E2 I | Protein Coding | 2 |
| 211 | SUMO1 | Small Ubiquitin Like Modifier 1 | Protein Coding | 2 |
| 212 | VRK1 | VRK Serine/Threonine Kinase 1 | Protein Coding | 2 |
| 213 | VRK2 | VRK Serine/Threonine Kinase 2 | Protein Coding | 2 |
| 214 | CHMP6 | Charged Multivesicular Body Protein 6 | Protein Coding | 2 |
| 215 | BANF1 | Barrier To Autointegration Nuclear Assembly Factor 1 | Protein Coding | 2 |
| 216 | CCNB1 | Cyclin B1 | Protein Coding | 2 |
| 217 | CCNB2 | Cyclin B2 | Protein Coding | 2 |
| 218 | CHMP7 | Charged Multivesicular Body Protein 7 | Protein Coding | 2 |
| 219 | CHMP4C | Charged Multivesicular Body Protein 4C | Protein Coding | 2 |
| 220 | NUP155 | Nucleoporin 155 | Protein Coding | 2 |
| 221 | NUP93 | Nucleoporin 93 | Protein Coding | 2 |
| 222 | IST1 | IST1 Factor Associated With ESCRT-III | Protein Coding | 2 |
| 223 | NUP58 | Nucleoporin 58 | Protein Coding | 2 |
| 224 | CDK1 | Cyclin Dependent Kinase 1 | Protein Coding | 2 |
| 225 | POM121 | POM121 Transmembrane Nucleoporin | Protein Coding | 2 |
| 226 | FBXO5 | F-Box Protein 5 | Protein Coding | 1 |
Disorders associated with Separation of Sister Chromatids SuperPath
according to GeneCards Suite gene sharing