Serotonin and anxiety

No Pathway Network information available for Serotonin and anxiety

Pathways in the Serotonin and anxiety SuperPath

#	Name	Source	Genes
1	Serotonin and anxiety	WikiPathways	ADRA1A ARC CAMK2B CRH FMR1 FOS GABRA1 GRM1 HTR1A HTR2A HTR2C PLCD4 PLEK POMC PPP3CA PRKCB TRPV1 (see all 17) (see less)
2	Serotonin and anxiety-related events	WikiPathways	ARC CRHR1 FOS GRIN2D HTR1A HTR2A HTR2C NLGN1 PLCD4 PLEK PPP3CA PRKCB (see all 12) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PLCD4	Phospholipase C Delta 4	Protein Coding	2
2	PRKCB	Protein Kinase C Beta	Protein Coding	2
3	PPP3CA	Protein Phosphatase 3 Catalytic Subunit Alpha	Protein Coding	2
4	PLEK	Pleckstrin	Protein Coding	2
5	HTR2C	5-Hydroxytryptamine Receptor 2C	Protein Coding	2
6	HTR2A	5-Hydroxytryptamine Receptor 2A	Protein Coding	2
7	HTR1A	5-Hydroxytryptamine Receptor 1A	Protein Coding	2
8	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	2
9	ARC	Activity Regulated Cytoskeleton Associated Protein	Protein Coding	2
10	CAMK2B	Calcium/Calmodulin Dependent Protein Kinase II Beta	Protein Coding	1
11	TRPV1	Transient Receptor Potential Cation Channel Subfamily V Member 1	Protein Coding	1
12	POMC	Proopiomelanocortin	Protein Coding	1
13	GRM1	Glutamate Metabotropic Receptor 1	Protein Coding	1
14	GABRA1	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha1	Protein Coding	1
15	FMR1	Fragile X Messenger Ribonucleoprotein 1	Protein Coding	1
16	ADRA1A	Adrenoceptor Alpha 1A	Protein Coding	1
17	CRH	Corticotropin Releasing Hormone	Protein Coding	1
18	GRIN2D	Glutamate Ionotropic Receptor NMDA Type Subunit 2D	Protein Coding	1
19	NLGN1	Neuroligin 1	Protein Coding	1
20	CRHR1	Corticotropin Releasing Hormone Receptor 1	Protein Coding	1

Disorders associated with Serotonin and anxiety SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Developmental and epileptic encephalopathy 91	Enrichment	PPP3CA	3.05
2	Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development	Enrichment	PPP3CA	3.05
3	Periodic fever, menstrual cycle-dependent	Enrichment	HTR1A	3.05
4	Autism 20	Enrichment	NLGN1	3.05
5	Undetermined early-onset epileptic encephalopathy	Enrichment	GRIN2D, PPP3CA	2.97
6	Epilepsy, idiopathic generalized 13	Enrichment	GABRA1	2.90
7	Spinocerebellar ataxia, autosomal recessive 13	Enrichment	GRM1	2.90
8	Intellectual developmental disorder, autosomal dominant 54	Enrichment	CAMK2B	2.90
9	Developmental and epileptic encephalopathy 19	Enrichment	GABRA1	2.90
10	Spinocerebellar ataxia 44	Enrichment	GRM1	2.90
11	Xq27.3q28 duplication syndrome	Enrichment	FMR1	2.90
12	Chondromyxoid fibroma	Enrichment	GRM1	2.90
13	Autosomal dominant non-syndromic intellectual disability	Enrichment	CAMK2B, PPP3CA	2.76
14	Obsessive-compulsive disorder	Enrichment	HTR2A	2.75
15	Developmental and epileptic encephalopathy 46	Enrichment	GRIN2D	2.75
16	Congenital generalized lipodystrophy	Enrichment	FOS	2.45
17	Obesity, early-onset, with adrenal insufficiency and red hair	Enrichment	POMC	2.43
18	Obesity due to pro-opiomelanocortin deficiency	Enrichment	POMC	2.43
19	Major depressive disorder	Enrichment	HTR2A	2.35
20	Histiocytoid hemangioma	Enrichment	FOS	2.35
21	Fragile x tremor/ataxia syndrome	Enrichment	FMR1	2.30
22	Fragile x-associated tremor/ataxia syndrome	Enrichment	FMR1	2.30
23	Premature ovarian failure 1	Enrichment	FMR1	2.20
24	Fragile x syndrome	Enrichment	FMR1	2.20
25	Childhood absence epilepsy	Enrichment	GABRA1	2.13
26	Autosomal dominant sleep-related hypermotor epilepsy	Enrichment	CRH	2.06
27	Dravet syndrome	Enrichment	GABRA1	1.90
28	Epilepsy, myoclonic juvenile	Enrichment	GABRA1	1.86
29	Epilepsy, idiopathic generalized	Enrichment	GABRA1	1.86
30	Dystonia	Enrichment	CAMK2B	1.37
31	Epilepsy	Enrichment	GABRA1	1.31
32	Schizophrenia	Enrichment	HTR2A	1.29
33	Body mass index quantitative trait locus 11	Enrichment	POMC	1.22
34	Congenital nervous system abnormality	Enrichment	CAMK2B	0.90
35	Nervous system disease	Enrichment	CAMK2B	0.90
36	Microcephaly	Enrichment	CAMK2B	0.84

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Serotonin and anxiety

Pathway Network for Serotonin and anxiety

Member Pathways for Serotonin and anxiety

Pathways in the Serotonin and anxiety SuperPath

Associated Genes for Serotonin and anxiety

Associated Disorders for Serotonin and anxiety

Disorders associated with Serotonin and anxiety SuperPath

STRING Interaction Network for Serotonin and anxiety

Sources for Serotonin and anxiety