Serotonin and melatonin biosynthesis

No Pathway Network information available for Serotonin and melatonin biosynthesis

#	Name	Source	Genes
1	Serotonin and melatonin biosynthesis	Reactome	AANAT ASMT DDC TPH1 TPH2
2	serotonin and melatonin biosynthesis	PubChem	AANAT ASMT DDC TPH1 TPH2

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TPH2	Tryptophan Hydroxylase 2	Protein Coding	2
2	AANAT	Aralkylamine N-Acetyltransferase	Protein Coding	2
3	DDC	Dopa Decarboxylase	Protein Coding	2
4	ASMT	Acetylserotonin O-Methyltransferase	Protein Coding	2
5	TPH1	Tryptophan Hydroxylase 1	Protein Coding	2

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Major affective disorder 1	Enrichment	TPH2	3.13
2	Aromatic l-amino acid decarboxylase deficiency	Enrichment	DDC	3.13
3	Major depressive disorder	Enrichment	TPH2	2.73
4	Rasopathy	Enrichment	DDC	2.02

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Serotonin and melatonin biosynthesis