Signaling by FGFR2 amplification mutants

No Pathway Network information available for Signaling by FGFR2 amplification mutants

#	Name	Source	Genes
1	Signaling by FGFR2 amplification mutants	Reactome	FGFR2
2	Signaling by FGFR2 fusions	Reactome	FGFR2

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	FGFR2	Fibroblast Growth Factor Receptor 2	Protein Coding	2

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Beare-stevenson cutis gyrata syndrome	Enrichment	FGFR2	4.13
2	Scaphocephaly, maxillary retrusion, and impaired intellectual development	Enrichment	FGFR2	4.13
3	Apert syndrome	Enrichment	FGFR2	4.13
4	Bent bone dysplasia syndrome 1	Enrichment	FGFR2	4.13
5	Non-syndromic unicoronal craniosynostosis	Enrichment	FGFR2	4.13
6	Aural atresia, congenital	Enrichment	FGFR2	3.83
7	Pfeiffer syndrome	Enrichment	FGFR2	3.83
8	Jackson-weiss syndrome	Enrichment	FGFR2	3.83
9	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis	Enrichment	FGFR2	3.83
10	Split hand-foot malformation	Enrichment	FGFR2	3.83
11	Autosomal dominant nonsyndromic deafness	Enrichment	FGFR2	3.83
12	Crouzon syndrome	Enrichment	FGFR2	3.66
13	Lacrimoauriculodentodigital syndrome 1	Enrichment	FGFR2	3.66
14	Saethre-chotzen syndrome	Enrichment	FGFR2	3.53
15	Glioma	Enrichment	FGFR2	3.53
16	Hemifacial hyperplasia	Enrichment	FGFR2	3.43
17	Split-hand/foot malformation 1	Enrichment	FGFR2	3.35
18	Meier-gorlin syndrome 1	Enrichment	FGFR2	3.13
19	Hydrocephalus	Enrichment	FGFR2	2.96
20	Craniosynostosis	Enrichment	FGFR2	2.83
21	Endometrial cancer	Enrichment	FGFR2	2.81
22	Gastric cancer	Enrichment	FGFR2	2.50
23	Hypertelorism	Enrichment	FGFR2	2.42
24	Colorectal cancer	Enrichment	FGFR2	2.19

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Signaling by FGFR2 amplification mutants