Signaling by SCF-KIT

Pathway network for the Signaling by SCF-KIT SuperPath

Sources:

Reactome

Pathways in the Signaling by SCF-KIT SuperPath

#	Name	Source	Genes
1	Signaling by SCF-KIT	Reactome	CBL CHEK1 CMA1 FER FES FYN GAB2 GRAP GRAP2 GRB10 GRB2 GRB7 HRAS JAK2 KIT KITLG KRAS LCK LYN MMP9 NRAS PIK3CA PIK3R1 PIK3R2 PIK3R3 PRKCA PTPN11 PTPN6 PTPRU RAC1 SH2B2 SH2B3 SOCS1 SOCS6 SOS1 SRC STAT1 STAT3 STAT5A STAT5B VAV1 YES1 (see all 42) (see less)
2	Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	Reactome	FYN GRB2 HRAS JAK2 KIT KRAS LCK LYN NRAS PIK3CA PIK3R1 PIK3R2 PIK3R3 SOS1 SRC STAT1 STAT3 STAT5A STAT5B YES1 (see all 20) (see less)
3	Signaling by KIT in disease	Reactome	FYN GRB2 HRAS JAK2 KIT KRAS LCK LYN NRAS PIK3CA PIK3R1 PIK3R2 PIK3R3 SOS1 SRC STAT1 STAT3 STAT5A STAT5B YES1 (see all 20) (see less)
4	Regulation of KIT signaling	Reactome	CBL FYN GRB2 KIT KITLG LCK LYN PRKCA PTPN6 SH2B2 SH2B3 SOCS1 SOCS6 SOS1 SRC YES1 (see all 16) (see less)

Gene overlap in member pathways for Signaling by SCF-KIT SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	4
2	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	4
3	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	4
4	LCK	LCK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	4
5	LYN	LYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	4
6	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	4
7	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	4
8	YES1	YES Proto-Oncogene 1, Src Family Tyrosine Kinase	Protein Coding	4
9	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	3
10	JAK2	Janus Kinase 2	Protein Coding	3
11	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	3
12	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	3
13	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	3
14	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	3
15	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	3
16	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	3
17	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	3
18	STAT5A	Signal Transducer And Activator Of Transcription 5A	Protein Coding	3
19	STAT5B	Signal Transducer And Activator Of Transcription 5B	Protein Coding	3
20	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	3
21	SH2B3	SH2B Adaptor Protein 3	Protein Coding	2
22	SH2B2	SH2B Adaptor Protein 2	Protein Coding	2
23	KITLG	KIT Ligand	Protein Coding	2
24	PRKCA	Protein Kinase C Alpha	Protein Coding	2
25	PTPN6	Protein Tyrosine Phosphatase Non-Receptor Type 6	Protein Coding	2
26	SOCS1	Suppressor Of Cytokine Signaling 1	Protein Coding	2
27	CBL	Cbl Proto-Oncogene	Protein Coding	2
28	SOCS6	Suppressor Of Cytokine Signaling 6	Protein Coding	2
29	PTPRU	Protein Tyrosine Phosphatase Receptor Type U	Protein Coding	1
30	GRAP	GRB2 Related Adaptor Protein	Protein Coding	1
31	CHEK1	Checkpoint Kinase 1	Protein Coding	1
32	CMA1	Chymase 1	Protein Coding	1
33	FER	FER Tyrosine Kinase	Protein Coding	1
34	FES	FES Proto-Oncogene, Tyrosine Kinase	Protein Coding	1
35	GRB7	Growth Factor Receptor Bound Protein 7	Protein Coding	1
36	GRB10	Growth Factor Receptor Bound Protein 10	Protein Coding	1
37	MMP9	Matrix Metallopeptidase 9	Protein Coding	1
38	PTPN11	Protein Tyrosine Phosphatase Non-Receptor Type 11	Protein Coding	1
39	RAC1	Rac Family Small GTPase 1	Protein Coding	1
40	VAV1	Vav Guanine Nucleotide Exchange Factor 1	Protein Coding	1
41	GRAP2	GRB2 Related Adaptor Protein 2	Protein Coding	1
42	GAB2	GRB2 Associated Binding Protein 2	Protein Coding	1

Disorders associated with Signaling by SCF-KIT SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome and noonan-related syndrome	Enrichment	CBL, HRAS, KRAS, NRAS, PTPN11, SOS1	10.78
2	Noonan syndrome 1	Enrichment	CBL, HRAS, KRAS, NRAS, PTPN11, SOS1	10.12
3	Rasopathy	Enrichment	CBL, HRAS, KRAS, NRAS, PTPN11, SOS1	9.90
4	Nevus, epidermal	Enrichment	HRAS, KRAS, NRAS, PIK3CA	9.87
5	Lung non-small cell carcinoma	Enrichment	HRAS, KRAS, NRAS, PIK3CA	8.94
6	Noonan syndrome 3	Enrichment	HRAS, KRAS, PTPN11, SOS1	8.56
7	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	7.96
8	Juvenile myelomonocytic leukemia	Enrichment	CBL, KRAS, NRAS, PTPN11	7.41
9	Leukemia, acute myeloid	Enrichment	JAK2, KIT, KRAS, NRAS	6.52
10	Lip and oral cavity carcinoma	Enrichment	HRAS, KIT, PIK3CA	6.22
11	Myelofibrosis	Enrichment	JAK2, SH2B3, SRC	6.02
12	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	5.69
13	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	5.21
14	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	5.21
15	Breast implant-associated anaplastic large cell lymphoma	Enrichment	JAK2, STAT3	5.21
16	Colorectal cancer	Enrichment	NRAS, PIK3CA, PIK3R1, SRC	5.15
17	Bladder cancer	Enrichment	HRAS, KRAS, PIK3CA	5.01
18	Differentiated thyroid carcinoma	Enrichment	HRAS, KRAS, NRAS	5.01
19	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3CA, PIK3R2	4.91
20	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS, NRAS	4.91
21	Testicular germ cell tumor	Enrichment	KIT, KITLG	4.71
22	Breast adenocarcinoma	Enrichment	KRAS, PIK3CA	4.51
23	Lung squamous cell carcinoma	Enrichment	KRAS, PIK3CA	4.51
24	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS, NRAS	4.36
25	Capillary malformation-arteriovenous malformation 1	Enrichment	KRAS, PIK3CA	4.36
26	Leukemia, chronic myeloid	Enrichment	KRAS, NRAS	4.36
27	Gallbladder cancer	Enrichment	KRAS, PIK3CA	4.36
28	Follicular thyroid carcinoma	Enrichment	HRAS, NRAS	4.36
29	Erythrocytosis, familial, 1	Enrichment	JAK2, SH2B3	4.25
30	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CBL, PTPN11	4.25
31	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, NRAS	4.24
32	Arteriovenous malformation	Enrichment	HRAS, PIK3CA	4.13
33	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, PIK3CA	4.03
34	Myeloproliferative neoplasm	Enrichment	CBL, JAK2	4.03
35	Non-immune hydrops fetalis	Enrichment	HRAS, KRAS, PTPN11	3.93
36	Acute promyelocytic leukemia	Enrichment	STAT3, STAT5B	3.80
37	Essential thrombocythemia	Enrichment	JAK2, SH2B3	3.71
38	Lynch syndrome	Enrichment	KRAS, PIK3CA	3.67
39	Ovarian cancer	Enrichment	KIT, KRAS, PIK3CA	3.38
40	Myeloma, multiple	Enrichment	KRAS, PIK3R2, SH2B3	3.17
41	Lung cancer	Enrichment	KRAS, PIK3CA	3.00
42	Rhabdomyosarcoma	Enrichment	CBL, HRAS	2.96
43	Noonan syndrome 4	Enrichment	SOS1	2.93
44	Mastocytosis, cutaneous	Enrichment	KIT	2.93
45	Hyperpigmentation with or without hypopigmentation, familial progressive	Enrichment	KITLG	2.93
46	Skin/hair/eye pigmentation, variation in, 7	Enrichment	KITLG	2.93
47	Immunodeficiency 22	Enrichment	LCK	2.93
48	Thrombocytopenia 6	Enrichment	SRC	2.93
49	Autoinflammatory disease, systemic, with vasculitis	Enrichment	LYN	2.93
50	Chronic mast cell leukemia	Enrichment	KIT	2.93
51	Deafness, autosomal dominant 69	Enrichment	KITLG	2.93
52	Isolated bone marrow mastocytosis	Enrichment	KIT	2.93
53	Smoldering systemic mastocytosis	Enrichment	KIT	2.93
54	Vegetative pyoderma gangrenosum	Enrichment	PTPN6	2.93
55	Bullous pyoderma gangrenosum	Enrichment	PTPN6	2.93
56	Pustular pyoderma gangrenosum	Enrichment	PTPN6	2.93
57	Mastocytosis	Enrichment	KIT	2.93
58	Familial progressive hyperpigmentation	Enrichment	KITLG	2.93
59	Growth retardation-mild developmental delay-chronic hepatitis syndrome	Enrichment	SH2B3	2.93
60	Cutaneous mastocytoma	Enrichment	KIT	2.93
61	Typical urticaria pigmentosa	Enrichment	KIT	2.93
62	Classic pyoderma gangrenosum	Enrichment	PTPN6	2.93
63	Nodular urticaria pigmentosa	Enrichment	KIT	2.93
64	Pseudoxanthomatous diffuse cutaneous mastocytosis	Enrichment	KIT	2.93
65	Telangiectasia macularis eruptiva perstans	Enrichment	KIT	2.93
66	Acute mast cell leukemia	Enrichment	KIT	2.93
67	Familial progressive hyper- and hypopigmentation	Enrichment	KITLG	2.93
68	Plaque-form urticaria pigmentosa	Enrichment	KIT	2.93
69	Bullous diffuse cutaneous mastocytosis	Enrichment	KIT	2.93
70	Testis seminoma	Enrichment	KIT	2.93
71	Macrodactyly	Enrichment	PIK3CA	2.83
72	Oculoectodermal syndrome	Enrichment	KRAS	2.83
73	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.83
74	Cowden syndrome 5	Enrichment	PIK3CA	2.83
75	Melanosis, neurocutaneous	Enrichment	NRAS	2.83
76	Noonan syndrome 6	Enrichment	NRAS	2.83
77	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.83
78	Growth hormone insensitivity syndrome with immune dysregulation 2, autosomal dominant	Enrichment	STAT5B	2.83
79	Short syndrome	Enrichment	PIK3R1	2.83
80	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	2.83
81	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	2.83
82	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.83
83	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.83
84	Immunodeficiency 31a	Enrichment	STAT1	2.83
85	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.83
86	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.83
87	Immunodeficiency 31b	Enrichment	STAT1	2.83
88	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	2.83
89	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.83
90	Hypospadias	Enrichment	PIK3CA	2.83
91	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	2.83
92	Congenital pulmonary airway malformation	Enrichment	KRAS	2.83
93	Rare venous malformation	Enrichment	PIK3CA	2.83
94	Diaphragmatic eventration	Enrichment	PIK3CA	2.83
95	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.83
96	Rare combined vascular malformation	Enrichment	PIK3CA	2.83
97	Cavernous lymphangioma	Enrichment	PIK3CA	2.83
98	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.83
99	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.83
100	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.83
101	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	2.83
102	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.83
103	Macrodactyly of toe	Enrichment	PIK3CA	2.83
104	Neurocutaneous melanocytosis	Enrichment	NRAS	2.83
105	Diffuse large b-cell lymphoma	Enrichment	SOCS1, STAT3	2.81
106	Gastric cancer	Enrichment	KRAS, PIK3CA	2.75
107	Hereditary breast carcinoma	Enrichment	KRAS, PIK3CA	2.73
108	Fibromatosis, gingival, 1	Enrichment	SOS1	2.63
109	Ovarian germ cell cancer	Enrichment	CBL	2.63
110	Pulmonic stenosis	Enrichment	SOS1	2.63
111	Piebald trait	Enrichment	KIT	2.63
112	Waardenburg syndrome, type 2f	Enrichment	KITLG	2.63
113	Malignant germ cell tumor of ovary	Enrichment	CBL	2.63
114	B-lymphoblastic leukemia/lymphoma with t	Enrichment	KIT	2.63
115	Hydrops fetalis, nonimmune	Enrichment	HRAS, PTPN11	2.54
116	Costello syndrome	Enrichment	HRAS	2.53
117	Growth hormone insensitivity syndrome with immune dysregulation 1, autosomal recessive	Enrichment	STAT5B	2.53
118	Keratosis, seborrheic	Enrichment	PIK3CA	2.53
119	Encephalocraniocutaneous lipomatosis	Enrichment	KRAS	2.53
120	Noonan syndrome 8	Enrichment	PIK3CA	2.53
121	Thrombocythemia 3	Enrichment	JAK2	2.53
122	Immunodeficiency 31c	Enrichment	STAT1	2.53
123	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	2.53
124	Polycythemia	Enrichment	JAK2	2.53
125	Hypereosinophilic syndrome	Enrichment	JAK2	2.53
126	Laron syndrome with immunodeficiency	Enrichment	STAT5B	2.53
127	Wooly hair nevus	Enrichment	HRAS	2.53
128	Metachondromatosis	Enrichment	PTPN11	2.51
129	Leopard syndrome 1	Enrichment	PTPN11	2.51
130	Deafness, autosomal recessive 114	Enrichment	GRAP	2.51
131	Oocyte/zygote/embryo maturation arrest 21	Enrichment	CHEK1	2.51
132	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.51
133	Silver-russell syndrome due to maternal uniparental disomy of chromosome 7	Enrichment	GRB10	2.51
134	Malignant astrocytoma	Enrichment	PTPN11	2.51
135	Thrombocythemia 1	Enrichment	SH2B3	2.45
136	Immune thrombocytopenia	Enrichment	SOCS1	2.45
137	Nuchal bleb, familial	Enrichment	SOS1	2.45
138	Neutrophilic dermatosis, acute febrile	Enrichment	PTPN6	2.45
139	Autoinflammatory syndrome, familial, with or without immunodeficiency	Enrichment	SOCS1	2.45
140	Testicular germ cell cancer	Enrichment	KIT	2.45
141	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	STAT3	2.35
142	Polycythemia vera	Enrichment	JAK2	2.35
143	Pompe disease, infantile-onset	Enrichment	PIK3CA	2.35
144	Langerhans cell histiocytosis	Enrichment	NRAS	2.35
145	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	2.35
146	Hyper ige syndrome	Enrichment	STAT3	2.35
147	Immunodeficiency 14	Enrichment	PIK3R1	2.35
148	Spermatocytoma	Enrichment	HRAS	2.35
149	Keratoacanthoma	Enrichment	PIK3CA	2.35
150	Anemia, autoimmune hemolytic	Enrichment	SOCS1	2.33
151	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	KIT	2.33
152	Systemic mastocytosis with associated hematologic neoplasm	Enrichment	KIT	2.33
153	Gingival fibromatosis	Enrichment	SOS1	2.33
154	Breast cancer	Enrichment	KRAS, PIK3CA	2.27
155	Acute myeloid leukemia with maturation	Enrichment	KIT	2.23
156	Aggressive systemic mastocytosis	Enrichment	CBL	2.23
157	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	KIT	2.23
158	Cardiofaciocutaneous syndrome 1	Enrichment	KRAS	2.23
159	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	2.23
160	Budd-chiari syndrome	Enrichment	JAK2	2.23
161	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	PIK3R2	2.23
162	Cardiofaciocutaneous syndrome	Enrichment	KRAS	2.23
163	Lung sarcomatoid carcinoma	Enrichment	KRAS	2.23
164	Cerebrovascular disease	Enrichment	PIK3CA	2.23
165	Pilocytic astrocytoma	Enrichment	KRAS	2.23
166	Epidermolytic nevus	Enrichment	HRAS	2.23
167	Familial cerebral cavernous malformations	Enrichment	PIK3CA	2.23
168	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	2.21
169	Werner syndrome	Enrichment	PTPN11	2.21
170	Metaphyseal anadysplasia 2	Enrichment	MMP9	2.21
171	Metaphyseal anadysplasia	Enrichment	MMP9	2.21
172	Capillary malformations, congenital	Enrichment	PIK3CA	2.13
173	Hemimegalencephaly	Enrichment	PIK3CA	2.13
174	Inherited cancer-predisposing syndrome	Enrichment	KIT, PTPN11, SH2B3	2.11
175	Gastrointestinal stromal tumor	Enrichment	KIT	2.08
176	Waardenburg syndrome, type 2e	Enrichment	KITLG	2.08
177	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	2.05
178	Cowden syndrome 1	Enrichment	PIK3CA	2.05
179	Hemihyperplasia, isolated	Enrichment	PIK3CA	2.05
180	Chronic mucocutaneous candidiasis	Enrichment	STAT1	2.05
181	Tricuspid valve insufficiency	Enrichment	PTPN11	2.03
182	Thrombocytopenia	Enrichment	PTPN11, SRC	2.02
183	Pilomyxoid astrocytoma	Enrichment	KRAS	1.99
184	Overgrowth syndrome	Enrichment	PIK3R1	1.99
185	Permanent neonatal diabetes mellitus	Enrichment	STAT3	1.93
186	Noonan syndrome with multiple lentigines	Enrichment	PTPN11	1.91
187	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	CHEK1	1.91
188	Leukemia, acute lymphoblastic 3	Enrichment	JAK2	1.88
189	Adult hepatocellular carcinoma	Enrichment	PIK3CA	1.88
190	Cowden syndrome	Enrichment	PIK3CA	1.88
191	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	1.83
192	Aortic valve disease 1	Enrichment	SOS1	1.82
193	Lymphoma	Enrichment	PTPN11	1.81
194	Osteoporosis	Enrichment	SRC	1.79
195	46,xy partial gonadal dysgenesis	Enrichment	SOS1	1.79
196	Meningioma	Enrichment	PIK3CA	1.76
197	Patent ductus arteriosus	Enrichment	PTPN11	1.73
198	Protein-deficiency anemia	Enrichment	NRAS	1.72
199	Lung cancer susceptibility 3	Enrichment	KRAS	1.69
200	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	1.56
201	Arteriovenous malformations of the brain	Enrichment	KRAS	1.56
202	Endometrial cancer	Enrichment	PIK3CA	1.52
203	Hepatocellular carcinoma	Enrichment	PIK3CA	1.50
204	Pectus excavatum	Enrichment	PTPN11	1.47
205	Specific learning disability	Enrichment	PTPN11	1.47
206	Pancreatic cancer	Enrichment	KRAS	1.44
207	Epicanthus	Enrichment	PTPN11	1.44
208	Congenital long qt syndrome	Enrichment	PTPN11	1.44
209	Severe combined immunodeficiency	Enrichment	LCK	1.42
210	Prostate cancer	Enrichment	PIK3CA	1.38
211	Systemic lupus erythematosus	Enrichment	SOCS1	1.35
212	Patent foramen ovale	Enrichment	PTPN11	1.27
213	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	KITLG	1.22
214	Scoliosis	Enrichment	PTPN11	1.14
215	Hypertelorism	Enrichment	PIK3CA	1.13
216	Hereditary breast ovarian cancer syndrome	Enrichment	KRAS	1.11
217	Strabismus	Enrichment	PTPN11	1.09
218	Primary ovarian insufficiency	Enrichment	JAK2	1.08
219	Long qt syndrome 1	Enrichment	PTPN11	1.05
220	Hypertrophic cardiomyopathy	Enrichment	PTPN11	0.90
221	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	PTPN11	0.80
222	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	GRAP	0.62
223	Autism spectrum disorder	Enrichment	PTPN11	0.54
224	Microcephaly	Enrichment	PTPN11	0.50

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Signaling by SCF-KIT

Pathway Network for Signaling by SCF-KIT

Pathway network for the Signaling by SCF-KIT SuperPath

Member Pathways for Signaling by SCF-KIT

Pathways in the Signaling by SCF-KIT SuperPath

Gene overlap in member pathways for Signaling by SCF-KIT SuperPath

Associated Genes for Signaling by SCF-KIT

Associated Disorders for Signaling by SCF-KIT

Disorders associated with Signaling by SCF-KIT SuperPath

STRING Interaction Network for Signaling by SCF-KIT

Sources for Signaling by SCF-KIT