Signaling by TGFB family members

Pathway network for the Signaling by TGFB family members SuperPath

Sources:

Reactome
Tocris

Pathways in the Signaling by TGFB family members SuperPath

#	Name	Source	Genes
1	Signaling by TGFB family members	Reactome	ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 AGO1 AGO2 AGO3 AGO4 AMH AMHR2 APH1A APH1B ARHGEF18 ARRB1 ARRB2 ATP1B4 BAMBI BMP10 BMP2 BMPR1A BMPR1B BMPR2 CBL CCNC CCNK CCNT1 CCNT2 CDK8 CDK9 CDKN2B CER1 CGN CHRDL1 COL1A2 DRAP1 E2F4 E2F5 EP300 F11R FBN1 FGF2 FKBP1A FOXH1 FST FSTL1 FSTL3 FURIN GDF2 GIPC1 GREM2 HDAC1 HELLS INHA INHBA INHBB ITGA8 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 JUNB KLF16 LTBP1 LTBP2 LTBP3 LTBP4 MAPK1 MAPK3 MEN1 MMP14 MMP16 MOV10 MTMR4 MYC MYCN MYF5 MYF6 MYOD1 MYOG NCOR1 NCOR2 NCSTN NEDD4L NEDD8 NOG PARD3 PARD6A PARP1 PMEPA1 PPM1A PPP1CA PPP1CB PPP1CC PPP1R15A PRKCZ PSEN1 PSEN2 PSENEN RARA RBL1 RHOA RNF111 RPS27A RXRA SERPINE1 SKI SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMAD7 SMAD9 SMURF1 SMURF2 SNW1 SP1 STAT1 STRAP STUB1 TCF12 TCF3 TCF4 TFDP1 TFDP2 TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TGFBR3 TGIF1 TGIF2 TIMP1 TIMP2 TNRC6A TNRC6B TNRC6C TRIM33 UBA52 UBB UBC UBE2D1 UBE2D3 UBE2M UCHL5 USP15 USP9X WWTR1 XPO1 YBX1 ZFYVE16 ZFYVE9 (see all 158) (see less)
2	Signaling by TGF-beta Receptor Complex	Reactome	ARHGEF18 ATP1B4 BAMBI CBL CCNC CCNK CCNT1 CCNT2 CDK8 CDK9 CDKN2B CGN COL1A2 E2F4 E2F5 EP300 F11R FBN1 FKBP1A FURIN HDAC1 ITGA8 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 JUNB LTBP1 LTBP2 LTBP3 LTBP4 MAPK1 MAPK3 MEN1 MTMR4 MYC NCOR1 NCOR2 NEDD4L NEDD8 PARD3 PARD6A PARP1 PMEPA1 PPM1A PPP1CA PPP1CB PPP1CC PPP1R15A PRKCZ RBL1 RHOA RNF111 RPS27A SERPINE1 SKI SKIL SMAD2 SMAD3 SMAD4 SMAD7 SMURF1 SMURF2 SNW1 SP1 STAT1 STRAP STUB1 TFDP1 TFDP2 TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TGFBR3 TGIF1 TGIF2 TRIM33 UBA52 UBB UBC UBE2D1 UBE2D3 UBE2M UCHL5 USP15 USP9X WWTR1 XPO1 YBX1 ZFYVE9 (see all 94) (see less)
3	Signaling by Activin	Reactome	ACVR1B ACVR1C ACVR2A ACVR2B DRAP1 FOXH1 FST FSTL3 INHA INHBA INHBB MAPK1 MAPK3 SMAD2 SMAD3 SMAD4 TGFBR3 (see all 17) (see less)
4	TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Reactome	ARHGEF18 CGN F11R FKBP1A PARD3 PARD6A PRKCZ RHOA RPS27A SMURF1 TGFB1 TGFBR1 TGFBR2 UBA52 UBB UBC (see all 16) (see less)
5	Regulation of CDH1 mRNA translation by microRNAs	Reactome	AGO1 AGO2 AGO3 AGO4 MOV10 MYC MYCN TNRC6A TNRC6B TNRC6C (see all 10) (see less)
6	Notch Pathway	Tocris	MYC MYCN PSEN1 PSEN2 PSENEN
7	TGFBR3 regulates activin signaling	Reactome	ACVR2A INHA INHBA TGFBR3
8	Antagonism of Activin by Follistatin	Reactome	FST FSTL3 INHBA INHBB

Gene overlap in member pathways for Signaling by TGFB family members SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	INHBA	Inhibin Subunit Beta A	Protein Coding	4
2	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	4
3	TGFBR3	Transforming Growth Factor Beta Receptor 3	Protein Coding	4
4	FSTL3	Follistatin Like 3	Protein Coding	3
5	FST	Follistatin	Protein Coding	3
6	FKBP1A	FKBP Prolyl Isomerase 1A	Protein Coding	3
7	ARHGEF18	Rho/Rac Guanine Nucleotide Exchange Factor 18	Protein Coding	3
8	INHA	Inhibin Subunit Alpha	Protein Coding	3
9	INHBB	Inhibin Subunit Beta B	Protein Coding	3
10	RHOA	Ras Homolog Family Member A	Protein Coding	3
11	SMAD2	SMAD Family Member 2	Protein Coding	3
12	SMAD3	SMAD Family Member 3	Protein Coding	3
13	SMAD4	SMAD Family Member 4	Protein Coding	3
14	MYCN	MYCN Proto-Oncogene, BHLH Transcription Factor	Protein Coding	3
15	F11R	F11 Receptor	Protein Coding	3
16	PARD6A	Par-6 Family Cell Polarity Regulator Alpha	Protein Coding	3
17	PRKCZ	Protein Kinase C Zeta	Protein Coding	3
18	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	3
19	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	3
20	PARD3	Par-3 Family Cell Polarity Regulator	Protein Coding	3
21	SMURF1	SMAD Specific E3 Ubiquitin Protein Ligase 1	Protein Coding	3
22	CGN	Cingulin	Protein Coding	3
23	RPS27A	Ribosomal Protein S27a	Protein Coding	3
24	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	3
25	TGFBR1	Transforming Growth Factor Beta Receptor 1	Protein Coding	3
26	TGFBR2	Transforming Growth Factor Beta Receptor 2	Protein Coding	3
27	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	3
28	UBB	Ubiquitin B	Protein Coding	3
29	UBC	Ubiquitin C	Protein Coding	3
30	ACVR2A	Activin A Receptor Type 2A	Protein Coding	3
31	CDK8	Cyclin Dependent Kinase 8	Protein Coding	2
32	CDK9	Cyclin Dependent Kinase 9	Protein Coding	2
33	STUB1	STIP1 Homology And U-Box Containing Protein 1	Protein Coding	2
34	CDKN2B	Cyclin Dependent Kinase Inhibitor 2B	Protein Coding	2
35	DRAP1	DR1 Associated Protein 1	Protein Coding	2
36	STRAP	Serine/Threonine Kinase Receptor Associated Protein	Protein Coding	2
37	COL1A2	Collagen Type I Alpha 2 Chain	Protein Coding	2
38	ACVR1C	Activin A Receptor Type 1C	Protein Coding	2
39	PARP1	Poly(ADP-Ribose) Polymerase 1	Protein Coding	2
40	E2F4	E2F Transcription Factor 4	Protein Coding	2
41	E2F5	E2F Transcription Factor 5	Protein Coding	2
42	AGO3	Argonaute RISC Catalytic Component 3	Protein Coding	2
43	AGO4	Argonaute RISC Component 4	Protein Coding	2
44	EP300	EP300 Lysine Acetyltransferase	Protein Coding	2
45	FBN1	Fibrillin 1	Protein Coding	2
46	SNW1	SNW Domain Containing 1	Protein Coding	2
47	TNRC6B	Trinucleotide Repeat Containing Adaptor 6B	Protein Coding	2
48	NEDD4L	NEDD4 Like E3 Ubiquitin Protein Ligase	Protein Coding	2
49	ATP1B4	ATPase Na+/K+ Transporting Family Member Beta 4	Protein Coding	2
50	PPP1R15A	Protein Phosphatase 1 Regulatory Subunit 15A	Protein Coding	2
51	BAMBI	BMP And Activin Membrane Bound Inhibitor	Protein Coding	2
52	WWTR1	WW Domain Containing Transcription Regulator 1	Protein Coding	2
53	AGO1	Argonaute RISC Component 1	Protein Coding	2
54	AGO2	Argonaute RISC Catalytic Component 2	Protein Coding	2
55	TNRC6A	Trinucleotide Repeat Containing Adaptor 6A	Protein Coding	2
56	HDAC1	Histone Deacetylase 1	Protein Coding	2
57	ITGAV	Integrin Subunit Alpha V	Protein Coding	2
58	ITGB1	Integrin Subunit Beta 1	Protein Coding	2
59	ITGB3	Integrin Subunit Beta 3	Protein Coding	2
60	ITGB5	Integrin Subunit Beta 5	Protein Coding	2
61	ITGB6	Integrin Subunit Beta 6	Protein Coding	2
62	ITGB8	Integrin Subunit Beta 8	Protein Coding	2
63	JUNB	JunB Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	2
64	LTBP1	Latent Transforming Growth Factor Beta Binding Protein 1	Protein Coding	2
65	LTBP2	Latent Transforming Growth Factor Beta Binding Protein 2	Protein Coding	2
66	LTBP3	Latent Transforming Growth Factor Beta Binding Protein 3	Protein Coding	2
67	SMAD7	SMAD Family Member 7	Protein Coding	2
68	MEN1	Menin 1	Protein Coding	2
69	MOV10	Mov10 RNA Helicase	Protein Coding	2
70	NEDD8	NEDD8 Ubiquitin Like Modifier	Protein Coding	2
71	YBX1	Y-Box Binding Protein 1	Protein Coding	2
72	FURIN	Furin, Paired Basic Amino Acid Cleaving Enzyme	Protein Coding	2
73	SERPINE1	Serpin Family E Member 1	Protein Coding	2
74	UCHL5	Ubiquitin C-Terminal Hydrolase L5	Protein Coding	2
75	TRIM33	Tripartite Motif Containing 33	Protein Coding	2
76	RNF111	Ring Finger Protein 111	Protein Coding	2
77	PPM1A	Protein Phosphatase, Mg2+/Mn2+ Dependent 1A	Protein Coding	2
78	PPP1CA	Protein Phosphatase 1 Catalytic Subunit Alpha	Protein Coding	2
79	PPP1CB	Protein Phosphatase 1 Catalytic Subunit Beta	Protein Coding	2
80	PPP1CC	Protein Phosphatase 1 Catalytic Subunit Gamma	Protein Coding	2
81	PSENEN	Presenilin Enhancer, Gamma-Secretase Subunit	Protein Coding	2
82	PSEN1	Presenilin 1	Protein Coding	2
83	PSEN2	Presenilin 2	Protein Coding	2
84	PMEPA1	Prostate Transmembrane Protein, Androgen Induced 1	Protein Coding	2
85	TNRC6C	Trinucleotide Repeat Containing Adaptor 6C	Protein Coding	2
86	RBL1	RB Transcriptional Corepressor Like 1	Protein Coding	2
87	TGIF2	TGFB Induced Factor Homeobox 2	Protein Coding	2
88	SMURF2	SMAD Specific E3 Ubiquitin Protein Ligase 2	Protein Coding	2
89	SKI	SKI Proto-Oncogene	Protein Coding	2
90	SKIL	SKI Like Proto-Oncogene	Protein Coding	2
91	SP1	Sp1 Transcription Factor	Protein Coding	2
92	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	2
93	TFDP1	Transcription Factor Dp-1	Protein Coding	2
94	TFDP2	Transcription Factor Dp-2	Protein Coding	2
95	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	2
96	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	2
97	TGIF1	TGFB Induced Factor Homeobox 1	Protein Coding	2
98	UBE2D1	Ubiquitin Conjugating Enzyme E2 D1	Protein Coding	2
99	UBE2D3	Ubiquitin Conjugating Enzyme E2 D3	Protein Coding	2
100	XPO1	Exportin 1	Protein Coding	2
101	USP9X	Ubiquitin Specific Peptidase 9 X-Linked	Protein Coding	2
102	LTBP4	Latent Transforming Growth Factor Beta Binding Protein 4	Protein Coding	2
103	ITGA8	Integrin Subunit Alpha 8	Protein Coding	2
104	CBL	Cbl Proto-Oncogene	Protein Coding	2
105	CCNK	Cyclin K	Protein Coding	2
106	CCNC	Cyclin C	Protein Coding	2
107	FOXH1	Forkhead Box H1	Protein Coding	2
108	CCNT1	Cyclin T1	Protein Coding	2
109	UBE2M	Ubiquitin Conjugating Enzyme E2 M	Protein Coding	2
110	CCNT2	Cyclin T2	Protein Coding	2
111	ACVR1B	Activin A Receptor Type 1B	Protein Coding	2
112	MTMR4	Myotubularin Related Protein 4	Protein Coding	2
113	ACVR2B	Activin A Receptor Type 2B	Protein Coding	2
114	ZFYVE9	Zinc Finger FYVE-Type Containing 9	Protein Coding	2
115	NCOR1	Nuclear Receptor Corepressor 1	Protein Coding	2
116	NCOR2	Nuclear Receptor Corepressor 2	Protein Coding	2
117	USP15	Ubiquitin Specific Peptidase 15	Protein Coding	2
118	GIPC1	GIPC PDZ Domain Containing Family Member 1	Protein Coding	1
119	FSTL1	Follistatin Like 1	Protein Coding	1
120	FGF2	Fibroblast Growth Factor 2	Protein Coding	1
121	NCSTN	Nicastrin	Protein Coding	1
122	GDF2	Growth Differentiation Factor 2	Protein Coding	1
123	AMH	Anti-Mullerian Hormone	Protein Coding	1
124	AMHR2	Anti-Mullerian Hormone Receptor Type 2	Protein Coding	1
125	BMP10	Bone Morphogenetic Protein 10	Protein Coding	1
126	HELLS	Helicase, Lymphoid Specific	Protein Coding	1
127	ARRB1	Arrestin Beta 1	Protein Coding	1
128	SMAD1	SMAD Family Member 1	Protein Coding	1
129	ARRB2	Arrestin Beta 2	Protein Coding	1
130	SMAD5	SMAD Family Member 5	Protein Coding	1
131	SMAD6	SMAD Family Member 6	Protein Coding	1
132	SMAD9	SMAD Family Member 9	Protein Coding	1
133	MMP14	Matrix Metallopeptidase 14	Protein Coding	1
134	MMP16	Matrix Metallopeptidase 16	Protein Coding	1
135	MYF5	Myogenic Factor 5	Protein Coding	1
136	MYF6	Myogenic Factor 6	Protein Coding	1
137	MYOD1	Myogenic Differentiation 1	Protein Coding	1
138	MYOG	Myogenin	Protein Coding	1
139	APH1A	Aph-1A Gamma-Secretase Subunit	Protein Coding	1
140	RARA	Retinoic Acid Receptor Alpha	Protein Coding	1
141	RXRA	Retinoid X Receptor Alpha	Protein Coding	1
142	GREM2	Gremlin 2, DAN Family BMP Antagonist	Protein Coding	1
143	BMP2	Bone Morphogenetic Protein 2	Protein Coding	1
144	BMPR1A	Bone Morphogenetic Protein Receptor Type 1A	Protein Coding	1
145	BMPR1B	Bone Morphogenetic Protein Receptor Type 1B	Protein Coding	1
146	BMPR2	Bone Morphogenetic Protein Receptor Type 2	Protein Coding	1
147	TCF4	Transcription Factor 4	Protein Coding	1
148	TCF3	Transcription Factor 3	Protein Coding	1
149	TCF12	Transcription Factor 12	Protein Coding	1
150	TIMP1	TIMP Metallopeptidase Inhibitor 1	Protein Coding	1
151	TIMP2	TIMP Metallopeptidase Inhibitor 2	Protein Coding	1
152	APH1B	Aph-1B Gamma-Secretase Subunit	Protein Coding	1
153	KLF16	KLF Transcription Factor 16	Protein Coding	1
154	CHRDL1	Chordin Like 1	Protein Coding	1
155	NOG	Noggin	Protein Coding	1
156	CER1	Cerberus 1, DAN Family BMP Antagonist	Protein Coding	1
157	ACVRL1	Activin A Receptor Like Type 1	Protein Coding	1
158	ZFYVE16	Zinc Finger FYVE-Type Containing 16	Protein Coding	1

Disorders associated with Signaling by TGFB family members SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	FBN1, SKI, SMAD2, SMAD3, SMAD4, TGFB2, TGFB3, TGFBR1, TGFBR2	10.74
2	Loeys-dietz syndrome	Enrichment	FBN1, SMAD2, SMAD3, TGFB2, TGFB3, TGFBR1, TGFBR2	10.59
3	Marfan syndrome	Enrichment	FBN1, LTBP2, TGFB2, TGFBR1, TGFBR2	8.45
4	Loeys-dietz syndrome 1	Enrichment	SMAD2, TGFBR1, TGFBR2	6.49
5	Alzheimer disease 4	Enrichment	PSEN1, PSEN2	6.49
6	Aortic aneurysm	Enrichment	FBN1, SMAD3, TGFBR1	5.89
7	Loeys-dietz syndrome 2	Enrichment	TGFBR1, TGFBR2	5.88
8	Early-onset autosomal dominant alzheimer disease	Enrichment	PSEN1, PSEN2	5.64
9	Heritable pulmonary arterial hypertension	Enrichment	ACVRL1, BMPR2, GDF2, SMAD9	5.26
10	Ehlers-danlos syndrome	Enrichment	COL1A2, SMAD3, TGFB2, TGFBR2	5.11
11	Acromicric dysplasia	Enrichment	FBN1, LTBP3	4.32
12	Loeys-dietz syndrome 4	Enrichment	TGFB2, TGFB3	4.32
13	Hereditary hemorrhagic telangiectasia	Enrichment	ACVRL1, GDF2, SMAD4	4.28
14	Complex neurodevelopmental disorder	Enrichment	AGO1, AGO2, TNRC6B	4.07
15	Craniosynostosis 7	Enrichment	BMP2, SMAD6	3.87
16	Weill-marchesani syndrome 1	Enrichment	FBN1, LTBP2	3.85
17	Geleophysic dysplasia	Enrichment	FBN1, LTBP3	3.85
18	Familial isolated dilated cardiomyopathy	Enrichment	PSEN1, PSEN2	3.83
19	Weill-marchesani syndrome	Enrichment	FBN1, LTBP2	3.55
20	Pseudomyogenic hemangioendothelioma	Enrichment	SERPINE1, WWTR1	3.55
21	Ovary adenocarcinoma	Enrichment	INHBA	3.53
22	Cardiomyopathy, dilated, 1v	Enrichment	PSEN2	3.43
23	Cardiomyopathy, dilated, 1u	Enrichment	PSEN1	3.43
24	Acne inversa, familial, 2, with or without dowling-degos disease	Enrichment	PSENEN	3.43
25	Acne inversa, familial, 3	Enrichment	PSEN1	3.43
26	Huntington's disease-like	Enrichment	PSEN2	3.43
27	Juvenile polyposis syndrome	Enrichment	BMPR1A, SMAD4	3.40
28	Transposition of the great arteries, dextro-looped	Enrichment	ACVR1B, BMP2	3.40
29	Pulmonary arterial hypertension associated with congenital heart disease	Enrichment	BMPR2, SMAD9	3.40
30	Pulmonary hypertension, primary, 1	Enrichment	ACVRL1, BMPR2, GDF2	3.39
31	Pancreatic cancer	Enrichment	ACVR1B, SMAD4	3.36
32	Goldberg-shprintzen syndrome	Enrichment	FBN1, SKI	3.33
33	Aortic aneurysm, familial thoracic 1	Enrichment	FBN1, SMAD3, SMAD6	3.29
34	Classic ehlers-danlos syndrome	Enrichment	COL1A2, TGFBR1	3.15
35	Burkitt lymphoma	Enrichment	MYC	3.13
36	Alzheimer disease 3	Enrichment	PSEN1	3.13
37	Pick disease of brain	Enrichment	PSEN1	3.13
38	Megalencephaly-polydactyly syndrome	Enrichment	MYCN	3.13
39	Familial retinoblastoma	Enrichment	MYCN	3.13
40	Global developmental delay with speech and behavioral abnormalities	Enrichment	TNRC6B	3.13
41	Epilepsy, familial adult myoclonic, 6	Enrichment	TNRC6A	3.13
42	Brachydactyly, type a2	Enrichment	BMP2, BMPR1B	3.10
43	Persistent mullerian duct syndrome, types i and ii	Enrichment	AMH, AMHR2	3.10
44	Persistent mullerian duct syndrome	Enrichment	AMH, AMHR2	3.10
45	Multiple endocrine neoplasia, type i	Enrichment	CDKN2B, MEN1	3.01
46	Retinoblastoma	Enrichment	MYCN	2.96
47	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	MYC	2.96
48	Heart, malformation of	Enrichment	CDK8, MAPK1, SMAD6	2.95
49	Orofacial cleft	Enrichment	FST	2.93
50	Orofacial clefting syndrome	Enrichment	FST	2.93
51	Multiple self-healing squamous epithelioma	Enrichment	TGFBR1	2.93
52	Retinitis pigmentosa 78	Enrichment	ARHGEF18	2.93
53	Colorectal cancer, hereditary nonpolyposis, type 6	Enrichment	TGFBR2	2.93
54	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	2.93
55	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	2.93
56	Noonan syndrome 13	Enrichment	MAPK1	2.90
57	Loeys-dietz syndrome 6	Enrichment	SMAD2	2.90
58	Congenital heart defects, multiple types, 8, with or without heterotaxy	Enrichment	SMAD2	2.90
59	Heritable thoracic aortic disease	Enrichment	SMAD4	2.90
60	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	BMPR1A, SMAD4	2.88
61	Connective tissue disease	Enrichment	FBN1, SMAD3, TGFBR2	2.86
62	Dowling-degos disease	Enrichment	PSENEN	2.83
63	2q23.1 microduplication syndrome	Enrichment	ACVR2A	2.83
64	Familial cerebral saccular aneurysm	Enrichment	TGFBR3	2.83
65	Premature ovarian failure 3	Enrichment	AGO2	2.83
66	Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures	Enrichment	AGO1	2.83
67	Familial thoracic aortic aneurysm and dissection	Enrichment	FBN1, SMAD3	2.78
68	Feingold syndrome 1	Enrichment	MYCN	2.73
69	Dementia	Enrichment	PSEN1	2.73
70	Atrial septal defect 1	Enrichment	BMP2, TGFB2	2.71
71	Myopathy, centronuclear, 1	Enrichment	MYF6, MYOD1	2.71
72	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	ACVRL1, PSEN1	2.71
73	Lessel-kreienkamp syndrome	Enrichment	AGO2	2.66
74	Camurati-engelmann disease 1	Enrichment	TGFB1	2.63
75	Microvascular complications of diabetes 5	Enrichment	TGFBR2	2.63
76	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	2.63
77	Camurati-engelmann disease	Enrichment	TGFB1	2.63
78	Submucosal cleft palate	Enrichment	UBB	2.63
79	Cleft hard palate	Enrichment	UBB	2.63
80	Myhre syndrome	Enrichment	SMAD4	2.60
81	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	2.60
82	Heterotaxy, visceral, 4, autosomal	Enrichment	ACVR2B	2.60
83	Loeys-dietz syndrome 3	Enrichment	SMAD3	2.60
84	Pectus excavatum	Enrichment	FBN1, TGFBR1	2.60
85	Semantic dementia	Enrichment	PSEN1	2.59
86	Neuroblastoma	Enrichment	MYCN	2.53
87	Progressive non-fluent aphasia	Enrichment	PSEN1	2.48
88	Behavioral variant of frontotemporal dementia	Enrichment	PSEN1	2.48
89	Diaphragmatic hernia, congenital	Enrichment	CDK8, FBN1	2.45
90	Neural tube defects	Enrichment	ITGB1, PARD3	2.45
91	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ, SKI	2.45
92	Uvula, bifid	Enrichment	UBB	2.45
93	Cleft soft palate	Enrichment	UBB	2.45
94	Frontotemporal dementia 1	Enrichment	PSEN1	2.39
95	Alzheimer's disease	Enrichment	PSEN1	2.32
96	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	2.30
97	Alzheimer disease, familial, 1	Enrichment	PSEN1	2.20
98	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	TNRC6B	2.18
99	Ectopia lentis 1, isolated, autosomal dominant	Enrichment	FBN1	2.16
100	Microspherophakia and/or megalocornea, with ectopia lentis and with or without secondary glaucoma	Enrichment	LTBP2	2.16
101	Ehlers-danlos syndrome, cardiac valvular type	Enrichment	COL1A2	2.16
102	Intellectual developmental disorder, x-linked 99	Enrichment	USP9X	2.16
103	Glaucoma 3, primary congenital, d	Enrichment	LTBP2	2.16
104	Holoprosencephaly 4	Enrichment	TGIF1	2.16
105	Shprintzen-goldberg craniosynostosis syndrome	Enrichment	SKI	2.16
106	Weill-marchesani syndrome 2	Enrichment	FBN1	2.16
107	Geleophysic dysplasia 2	Enrichment	FBN1	2.16
108	Protrusio acetabuli	Enrichment	FBN1	2.16
109	Weill-marchesani syndrome 3	Enrichment	LTBP2	2.16
110	Combined osteogenesis imperfecta and ehlers-danlos syndrome 2	Enrichment	COL1A2	2.16
111	Adrenal cortical adenoma	Enrichment	MEN1	2.16
112	Lymphoplasmacytic lymphoma	Enrichment	FBN1	2.16
113	Intellectual developmental disorder, x-linked 99, syndromic, female-restricted	Enrichment	USP9X	2.16
114	Plasminogen activator inhibitor-1 deficiency	Enrichment	SERPINE1	2.16
115	Camurati-engelmann disease 2	Enrichment	TGFB2	2.16
116	Geleophysic dysplasia 3	Enrichment	LTBP3	2.16
117	Immunodeficiency 31a	Enrichment	STAT1	2.16
118	Colorectal cancer 3	Enrichment	SMAD7	2.16
119	Immunodeficiency 31b	Enrichment	STAT1	2.16
120	Loeys-dietz syndrome 5	Enrichment	TGFB3	2.16
121	Cutis laxa, autosomal recessive, type iie	Enrichment	LTBP1	2.16
122	Noonan syndrome-like disorder with loose anagen hair 2	Enrichment	PPP1CB	2.16
123	Intellectual developmental disorder with hypertelorism and distinctive facies	Enrichment	CCNK	2.16
124	Periventricular nodular heterotopia 7	Enrichment	NEDD4L	2.16
125	Amelogenesis imperfecta, type ih	Enrichment	ITGB6	2.16
126	Female-restricted syndromic x-linked intellectual disability 99	Enrichment	USP9X	2.16
127	Glaucoma secondary to spherophakia/ectopia lentis and megalocornea	Enrichment	LTBP2	2.16
128	Developmental dysplasia of the hip 4	Enrichment	TRIM33	2.16
129	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	2.16
130	Adrenal adenoma	Enrichment	MEN1	2.16
131	Congenital plasminogen activator inhibitor type 1 deficiency	Enrichment	SERPINE1	2.16
132	Neonatal marfan syndrome	Enrichment	FBN1	2.16
133	Dislocation of the hip-dysmorphism syndrome	Enrichment	TRIM33	2.16
134	Hemihyperplasia, isolated	Enrichment	RHOA	2.15
135	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	2.15
136	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	2.15
137	Esophageal cancer	Enrichment	TGFBR2	2.08
138	Precursor t-cell acute lymphoblastic leukemia	Enrichment	MYC	2.07
139	Gallbladder cancer	Enrichment	SMAD4	2.06
140	Noonan syndrome 1	Enrichment	CBL, PPP1CB	1.96
141	Stapes ankylosis with broad thumbs and toes	Enrichment	NOG	1.93
142	Tarsal-carpal coalition syndrome	Enrichment	NOG	1.93
143	Telangiectasia, hereditary hemorrhagic, type 2	Enrichment	ACVRL1	1.93
144	Polyposis syndrome, hereditary mixed, 2	Enrichment	BMPR1A	1.93
145	Acromesomelic dysplasia 3	Enrichment	BMPR1B	1.93
146	Brachydactyly, type b2	Enrichment	NOG	1.93
147	Acne inversa, familial, 1	Enrichment	NCSTN	1.93
148	Symphalangism, proximal, 1a	Enrichment	NOG	1.93
149	Immunodeficiency-centromeric instability-facial anomalies syndrome 4	Enrichment	HELLS	1.93
150	Multiple synostoses syndrome 1	Enrichment	NOG	1.93
151	Brachydactyly, type a1, d	Enrichment	BMPR1B	1.93
152	Radioulnar synostosis, nonsyndromic	Enrichment	SMAD6	1.93
153	Agammaglobulinemia 8b, autosomal recessive	Enrichment	TCF3	1.93
154	Winchester syndrome	Enrichment	MMP14	1.93
155	Tooth agenesis, selective, 9	Enrichment	GREM2	1.93
156	Agammaglobulinemia 8a, autosomal dominant	Enrichment	TCF3	1.93
157	Ophthalmoplegia, external, with rib and vertebral anomalies	Enrichment	MYF5	1.93
158	Oculopharyngodistal myopathy 2	Enrichment	GIPC1	1.93
159	Craniosynostosis 3	Enrichment	TCF12	1.93
160	Telangiectasia, hereditary hemorrhagic, type 5	Enrichment	GDF2	1.93
161	Pulmonary hypertension, primary, 2	Enrichment	SMAD9	1.93
162	Congenital myopathy 17	Enrichment	MYOD1	1.93
163	Corneal dystrophy, fuchs endothelial, 3	Enrichment	TCF4	1.93
164	20p12.3 microdeletion syndrome	Enrichment	BMP2	1.93
165	Short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies 1	Enrichment	BMP2	1.93
166	Telangiectasis	Enrichment	ACVRL1	1.93
167	Primary pulmonary hypertension	Enrichment	BMPR2	1.93
168	Pulmonary hypertension	Enrichment	BMPR2	1.93
169	Drug- or toxin-induced pulmonary arterial hypertension	Enrichment	BMPR2	1.93
170	Hypogonadotropic hypogonadism 26 with or without anosmia	Enrichment	TCF12	1.93
171	Pash syndrome	Enrichment	NCSTN	1.93
172	Isolated congenital megalocornea	Enrichment	CHRDL1	1.93
173	Septopreoptic holoprosencephaly	Enrichment	FOXH1, TGIF1	1.89
174	Midline interhemispheric variant of holoprosencephaly	Enrichment	FOXH1, TGIF1	1.89
175	Specific learning disability	Enrichment	MAPK1	1.86
176	Bruck syndrome 1	Enrichment	COL1A2	1.86
177	Stiff skin syndrome	Enrichment	FBN1	1.86
178	Ebstein anomaly	Enrichment	CDK8	1.86
179	Ovarian germ cell cancer	Enrichment	CBL	1.86
180	Hyperparathyroidism 1	Enrichment	MEN1	1.86
181	Cutis laxa, autosomal recessive, type ic	Enrichment	LTBP4	1.86
182	Beaulieu-boycott-innes syndrome	Enrichment	FBN1	1.86
183	Immunodeficiency 31c	Enrichment	STAT1	1.86
184	Spinocerebellar ataxia 48	Enrichment	STUB1	1.86
185	Ehlers-danlos syndrome, arthrochalasia type, 2	Enrichment	COL1A2	1.86
186	Menke-hennekam syndrome 2	Enrichment	EP300	1.86
187	Noonan syndrome-like disorder with loose anagen hair	Enrichment	PPP1CB	1.86
188	Aortic dissection	Enrichment	FBN1	1.86
189	Marfanoid-progeroid-lipodystrophy syndrome	Enrichment	FBN1	1.86
190	Medullary thyroid carcinoma	Enrichment	MEN1	1.86
191	Insulinoma	Enrichment	MEN1	1.86
192	Intellectual developmental disorder with hypotonia and behavioral abnormalities	Enrichment	CDK8	1.86
193	Ehlers-danlos/osteogenesis imperfecta syndrome	Enrichment	COL1A2	1.86
194	Malignant germ cell tumor of ovary	Enrichment	CBL	1.86
195	Dentinogenesis imperfecta	Enrichment	COL1A2	1.86
196	Primary mediastinal large b-cell lymphoma	Enrichment	XPO1	1.86
197	Lens subluxation	Enrichment	FBN1	1.86
198	Null pituitary adenoma	Enrichment	MEN1	1.86
199	Silent pituitary adenoma	Enrichment	MEN1	1.86
200	Gigantism	Enrichment	MEN1	1.86
201	Rasopathy	Enrichment	CBL, PPP1CB	1.86
202	Microform holoprosencephaly	Enrichment	FOXH1, TGIF1	1.84
203	Lobar holoprosencephaly	Enrichment	FOXH1, TGIF1	1.84
204	Alobar holoprosencephaly	Enrichment	FOXH1, TGIF1	1.79
205	Lynch syndrome	Enrichment	TGFBR2	1.76
206	Semilobar holoprosencephaly	Enrichment	FOXH1, TGIF1	1.74
207	Thrombocytopenia	Enrichment	ACVRL1, ITGB3, SMAD4	1.74
208	Contractural arachnodactyly, congenital	Enrichment	FBN1	1.69
209	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3	1.69
210	Achondroplasia	Enrichment	FBN1	1.69
211	Mccune-albright syndrome	Enrichment	FBN1	1.69
212	Exfoliation syndrome	Enrichment	LTBP2	1.69
213	Bleeding disorder, platelet-type, 16	Enrichment	ITGB3	1.69
214	Muscular dystrophy, duchenne type	Enrichment	LTBP4	1.69
215	Chromosome 5q14.3 deletion syndrome, distal	Enrichment	NEDD4L	1.69
216	Pituitary adenoma 1, multiple types	Enrichment	MEN1	1.69
217	Autosomal recessive cutis laxa type i	Enrichment	LTBP1	1.69
218	Isolated ectopia lentis	Enrichment	FBN1	1.69
219	Cellular ependymoma	Enrichment	MEN1	1.69
220	Tanycytic ependymoma	Enrichment	MEN1	1.69
221	Papillary ependymoma	Enrichment	MEN1	1.69
222	Parathyroid adenoma	Enrichment	MEN1	1.69
223	Growth hormone secreting pituitary adenoma	Enrichment	MEN1	1.69
224	Aip familial isolated pituitary adenomas	Enrichment	MEN1	1.69
225	Familial isolated hyperparathyroidism	Enrichment	MEN1	1.69
226	High bone mass osteogenesis imperfecta	Enrichment	COL1A2	1.69
227	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	1.69
228	Clear cell ependymoma	Enrichment	MEN1	1.69
229	Alopecia - intellectual disability syndrome	Enrichment	ITGB6	1.69
230	Hyperpigmentation of the skin	Enrichment	USP9X	1.69
231	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	PSEN1	1.67
232	Craniosynostosis	Enrichment	SMAD6, TCF12	1.65
233	Pulmonary venoocclusive disease 1, autosomal dominant	Enrichment	BMPR2	1.64
234	Fibrodysplasia ossificans progressiva	Enrichment	BMPR2	1.64
235	Pulmonary venoocclusive disease 1	Enrichment	BMPR2	1.64
236	Aortic valve disease 2	Enrichment	SMAD6	1.64
237	Proximal symphalangism	Enrichment	NOG	1.64
238	Hereditary mixed polyposis syndrome	Enrichment	BMPR1A	1.64
239	Radioulnar synostosis	Enrichment	SMAD6	1.64
240	B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3)	Enrichment	TCF3	1.64
241	Pulmonary venoocclusive disease	Enrichment	BMPR2	1.64
242	B-lymphoblastic leukemia/lymphoma with t(17;19)	Enrichment	TCF3	1.64
243	Juvenile polyposis of infancy	Enrichment	BMPR1A	1.64
244	Idiopathic/heritable pulmonary arterial hypertension	Enrichment	BMPR2	1.64
245	Visceral heterotaxy	Enrichment	ACVR2B	1.56
246	Myeloma, multiple	Enrichment	NCOR2, RXRA, TCF3	1.56
247	Ehlers-danlos syndrome, arthrochalasia type, 1	Enrichment	COL1A2	1.56
248	Amelogenesis imperfecta, type iiia	Enrichment	ITGB6	1.56
249	Glaucoma 3, primary infantile, b	Enrichment	LTBP2	1.56
250	Malignant epithelioid hemangioendothelioma	Enrichment	WWTR1	1.56
251	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CBL	1.56
252	Prolactinoma	Enrichment	MEN1	1.56
253	Osteogenesis imperfecta with normal sclerae, dominant form	Enrichment	COL1A2	1.56
254	Mitral valve insufficiency	Enrichment	FBN1	1.56
255	Primary hyperparathyroidism	Enrichment	MEN1	1.56
256	Benign ependymoma	Enrichment	MEN1	1.56
257	Scoliosis	Enrichment	FBN1, MYF5	1.50
258	Polycystic liver disease 1 with or without kidney cysts	Enrichment	FBN1	1.47
259	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	1.47
260	Arthrogryposis, renal dysfunction, and cholestasis 1	Enrichment	FBN1	1.47
261	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.47
262	Glanzmann thrombasthenia 2	Enrichment	ITGB3	1.47
263	Polycystic liver disease 1	Enrichment	FBN1	1.47
264	Myeloproliferative neoplasm	Enrichment	CBL	1.47
265	Juvenile glaucoma	Enrichment	LTBP2	1.47
266	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	1.47
267	Aggressive systemic mastocytosis	Enrichment	CBL	1.47
268	Brachydactyly, type a1	Enrichment	BMPR1B	1.46
269	Brachydactyly, type c	Enrichment	BMPR1B	1.46
270	Acromesomelic dysplasia 2a	Enrichment	BMPR1B	1.46
271	Acromesomelic dysplasia 2c	Enrichment	BMPR1B	1.46
272	Megalocornea	Enrichment	CHRDL1	1.46
273	Acromesomelic dysplasia 2b	Enrichment	BMPR1B	1.46
274	Multicentric osteolysis, nodulosis, and arthropathy	Enrichment	MMP14	1.46
275	Cystic fibrosis	Enrichment	TGFB1	1.43
276	Congenital nervous system abnormality	Enrichment	PSEN1	1.41
277	Nervous system disease	Enrichment	PSEN1	1.41
278	Ehlers-danlos syndrome, classic type, 1	Enrichment	COL1A2	1.39
279	Glaucoma, primary open angle	Enrichment	LTBP2	1.39
280	Developmental dysplasia of the hip 1	Enrichment	TRIM33	1.39
281	Osteogenesis imperfecta, type i	Enrichment	COL1A2	1.39
282	Rubinstein-taybi syndrome 1	Enrichment	EP300	1.39
283	Dental anomalies and short stature	Enrichment	LTBP3	1.39
284	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	EP300	1.39
285	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	STUB1	1.39
286	Inguinal hernia	Enrichment	FBN1	1.39
287	Chronic mucocutaneous candidiasis	Enrichment	STAT1	1.39
288	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGB3	1.39
289	Hemophilia a	Enrichment	ACVRL1	1.34
290	Pitt-hopkins syndrome	Enrichment	TCF4	1.34
291	Factor viii deficiency	Enrichment	ACVRL1	1.34
292	Multiple synostoses syndrome	Enrichment	NOG	1.34
293	Non-syndromic bicoronal craniosynostosis	Enrichment	TCF12	1.34
294	Osteogenesis imperfecta, type ii	Enrichment	COL1A2	1.32
295	Glaucoma 3, primary congenital, a	Enrichment	LTBP2	1.32
296	Brugada syndrome 1	Enrichment	FBN1	1.32
297	Glanzmann thrombasthenia 1	Enrichment	ITGB3	1.32
298	Gastrointestinal stromal tumor	Enrichment	MEN1	1.32
299	Gastric cancer	Enrichment	SMAD4	1.28
300	Renal hypodysplasia/aplasia 1	Enrichment	ITGA8	1.27
301	Orthostatic intolerance	Enrichment	FBN1	1.27
302	Chondrosarcoma, extraskeletal myxoid	Enrichment	TCF12	1.24
303	Ventricular septal defect 1	Enrichment	BMP2	1.24
304	Cholangitis, primary sclerosing	Enrichment	TCF4	1.24
305	Fuchs' endothelial dystrophy	Enrichment	TCF4	1.24
306	Charge syndrome	Enrichment	EP300	1.22
307	Renal agenesis, bilateral	Enrichment	ITGA8	1.22
308	Amelogenesis imperfecta, type ie	Enrichment	ITGB6	1.17
309	Stroke, ischemic	Enrichment	FBN1	1.17
310	Melanoma	Enrichment	FBN1	1.17
311	Autosomal dominant macrothrombocytopenia	Enrichment	ITGB3	1.17
312	Primary bone dysplasia	Enrichment	COL1A2	1.17
313	Immunodeficiency-centromeric instability-facial anomalies syndrome	Enrichment	HELLS	1.17
314	Osteochondrodysplasia	Enrichment	COL1A2	1.13
315	Diabetes mellitus	Enrichment	MEN1	1.13
316	Autism spectrum disorder	Enrichment	TNRC6B	1.11
317	Oculopharyngodistal myopathy 1	Enrichment	GIPC1	1.10
318	Juvenile myelomonocytic leukemia	Enrichment	CBL	1.10
319	Cutis laxa	Enrichment	LTBP4	1.10
320	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	TGFB3	1.10
321	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	TGFB3	1.10
322	Osteogenesis imperfecta, type iv	Enrichment	COL1A2	1.06
323	Amelogenesis imperfecta	Enrichment	LTBP3	1.06
324	Spastic paraplegia 4, autosomal dominant	Enrichment	TCF4	1.05
325	Hemochromatosis, type 1	Enrichment	BMP2	1.05
326	Osteoporosis	Enrichment	COL1A2	1.03
327	Periventricular nodular heterotopia	Enrichment	NEDD4L	1.03
328	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	TGFB3	1.03
329	Polydactyly, postaxial, type a1	Enrichment	EP300	1.00
330	Osteogenesis imperfecta, type iii	Enrichment	COL1A2	1.00
331	Myopia	Enrichment	FBN1	1.00
332	Rare genetic intellectual disability	Enrichment	EP300	1.00
333	Noonan syndrome and noonan-related syndrome	Enrichment	CBL	1.00
334	Tooth agenesis, selective, 1	Enrichment	BMPR2	1.00
335	Polydactyly	Enrichment	SMAD6	1.00
336	Colorectal cancer	Enrichment	SMAD4	0.98
337	Hydrocephalus, congenital, 1	Enrichment	CDK8	0.98
338	Perrault syndrome 1	Enrichment	FBN1	0.98
339	Hypertension	Enrichment	MEN1	0.98
340	Rhabdomyosarcoma	Enrichment	CBL	0.98
341	Autosomal non-syndromic agammaglobulinemia	Enrichment	TCF3	0.96
342	Melanoma, cutaneous malignant 1	Enrichment	CDKN2B	0.95
343	Dandy-walker syndrome	Enrichment	PPP1CB	0.95
344	Familial colorectal cancer type x	Enrichment	BMPR1A	0.92
345	Epicanthus	Enrichment	TCF4	0.88
346	Aortic valve disease 1	Enrichment	SMAD6	0.85
347	Acute promyelocytic leukemia	Enrichment	RARA	0.85
348	Stereotypic movement disorder	Enrichment	TCF4	0.85
349	Myocardial infarction	Enrichment	ITGB3	0.85
350	Microcephaly	Enrichment	MAPK1	0.84
351	Brittle bone disorder	Enrichment	COL1A2	0.83
352	Inherited cancer-predisposing syndrome	Enrichment	SMAD4	0.81
353	Severe covid-19	Enrichment	ITGAV	0.74
354	Differentiated thyroid carcinoma	Enrichment	TRIM33	0.74
355	Arteriovenous malformations of the brain	Enrichment	ZFYVE16	0.70
356	Non-syndromic x-linked intellectual disability	Enrichment	USP9X	0.65
357	Retinitis pigmentosa	Enrichment	ARHGEF18	0.65
358	Tooth agenesis	Enrichment	GREM2	0.64
359	Skin disease	Enrichment	NCSTN	0.64
360	Myopathy	Enrichment	FBN1	0.61
361	Hereditary retinal dystrophy	Enrichment	ARHGEF18	0.53
362	Fundus dystrophy	Enrichment	ARHGEF18	0.53
363	Hereditary breast ovarian cancer syndrome	Enrichment	MEN1	0.50
364	Fetal akinesia deformation sequence 1	Enrichment	MYOD1	0.45
365	Distal arthrogryposis	Enrichment	MYOD1	0.41
366	Breast cancer	Enrichment	CDKN2B	0.39
367	Dilated cardiomyopathy	Enrichment	FBN1	0.37
368	Autosomal dominant non-syndromic intellectual disability	Enrichment	TCF4	0.35
369	Ovarian cancer	Enrichment	BMPR1A	0.16

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Signaling by TGFB family members

Pathway Network for Signaling by TGFB family members

Pathway network for the Signaling by TGFB family members SuperPath

Member Pathways for Signaling by TGFB family members

Pathways in the Signaling by TGFB family members SuperPath

Gene overlap in member pathways for Signaling by TGFB family members SuperPath

Associated Genes for Signaling by TGFB family members

Associated Disorders for Signaling by TGFB family members

Disorders associated with Signaling by TGFB family members SuperPath

STRING Interaction Network for Signaling by TGFB family members

Sources for Signaling by TGFB family members