Signaling by WNT

No Pathway Network information available for Signaling by WNT

Pathways in the Signaling by WNT SuperPath

#	Name	Source	Genes
1	Signaling by WNT	Reactome	ADRM1 AGO1 AGO2 AGO3 AGO4 AKT1 AKT2 AMER1 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APC ARRB2 ASH2L AXIN1 AXIN2 BCL9 BCL9L BTRC CALM1 CALM2 CALM3 CAMK2A CAV1 CBY1 CCDC88C CDC73 CHD8 CLTA CLTB CLTC CREBBP CSNK1A1 CSNK1E CSNK1G2 CSNK2A1 CSNK2A2 CSNK2B CTBP1 CTBP2 CTNNB1 CTNNBIP1 CUL1 CUL3 DAAM1 DACT1 DKK1 DKK2 DKK4 DVL1 DVL2 DVL3 EP300 FRAT1 FRAT2 FZD1 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 GNAO1 GNAT2 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GSK3B H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AJ H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-3A H3-3B H3-4 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HDAC1 HECW1 ITPR1 ITPR2 ITPR3 KAT5 KLHL12 KMT2D KRAS KREMEN1 KREMEN2 LEF1 LEO1 LGR4 LGR5 LGR6 LRP5 LRP6 MAP3K7 MEN1 MOV10 MYC NFATC1 NLK PARD6A PDE6A PDE6B PDE6G PFN1 PIP5K1B PLCB1 PLCB2 PLCB3 PORCN PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP3CA PPP3CB PPP3R1 PRICKLE1 PRKCA PRKCB PRKCG PRKG1 PRKG2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PYGO1 PYGO2 RAC1 RAC2 RAC3 RBBP5 RBX1 RHOA RNF146 RNF43 ROR1 ROR2 RPS27A RSPO1 RSPO2 RSPO3 RSPO4 RUNX3 RUVBL1 RYK SCRIB SEM1 SFRP1 SFRP2 SKP1 SMARCA4 SMURF1 SMURF2 SNX3 SOST SOX13 SOX17 SOX2 SOX3 SOX4 SOX6 SOX7 SOX9 SRY TCF7 TCF7L1 TCF7L2 TERT TLE1 TLE2 TLE3 TLE4 TLE5 TMED5 TNKS TNKS2 TNRC6A TNRC6B TNRC6C TRRAP UBA52 UBB UBC USP34 USP8 VANGL2 VPS26A VPS29 VPS35 WIF1 WLS WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B XPO1 YWHAZ ZNRF3 ZRANB1 (see all 316) (see less)
2	TCF dependent signaling in response to WNT	Reactome	ADRM1 AKT1 AKT2 AMER1 APC ASH2L AXIN1 AXIN2 BCL9 BCL9L BTRC CAV1 CBY1 CCDC88C CDC73 CHD8 CREBBP CSNK1A1 CSNK1E CSNK1G2 CSNK2A1 CSNK2A2 CSNK2B CTBP1 CTNNB1 CTNNBIP1 CUL3 DACT1 DKK1 DKK2 DKK4 DVL1 DVL2 DVL3 EP300 FRAT1 FRAT2 FZD1 FZD2 FZD4 FZD5 FZD6 FZD8 GSK3B H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AJ H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-3A H3-3B H3-4 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HDAC1 HECW1 KAT5 KLHL12 KMT2D KREMEN1 KREMEN2 LEF1 LEO1 LGR4 LGR5 LGR6 LRP5 LRP6 MEN1 MYC PIP5K1B PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PYGO1 PYGO2 RBBP5 RBX1 RNF146 RNF43 RPS27A RSPO1 RSPO2 RSPO3 RSPO4 RUNX3 RUVBL1 RYK SEM1 SFRP1 SFRP2 SMARCA4 SMURF2 SOST SOX13 SOX17 SOX2 SOX3 SOX4 SOX6 SOX7 SOX9 SRY TCF7 TCF7L1 TCF7L2 TERT TLE1 TLE2 TLE3 TLE4 TNKS TNKS2 TRRAP UBA52 UBB UBC USP34 USP8 WIF1 WNT1 WNT3 WNT3A WNT4 WNT5A WNT8A WNT8B WNT9A XPO1 YWHAZ ZNRF3 (see all 217) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	FRAT1	FRAT Regulator Of Wnt Signaling Pathway 1	Protein Coding	2
2	PSMD14	Proteasome 26S Subunit, Non-ATPase 14	Protein Coding	2
3	KAT5	Lysine Acetyltransferase 5	Protein Coding	2
4	ADRM1	ADRM1 26S Proteasome Ubiquitin Receptor	Protein Coding	2
5	WIF1	Wnt Inhibitory Factor 1	Protein Coding	2
6	H4C16	H4 Histone 16	Protein Coding	2
7	LEO1	LEO1 Component Of Paf1/RNA Polymerase II Complex	Protein Coding	2
8	H3C14	H3 Clustered Histone 14	Protein Coding	2
9	H2BC26	H2B Clustered Histone 26	Protein Coding	2
10	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	2
11	AMER1	APC Membrane Recruitment Protein 1	Protein Coding	2
12	CSNK1A1	Casein Kinase 1 Alpha 1	Protein Coding	2
13	CSNK1E	Casein Kinase 1 Epsilon	Protein Coding	2
14	CSNK1G2	Casein Kinase 1 Gamma 2	Protein Coding	2
15	CSNK2A1	Casein Kinase 2 Alpha 1	Protein Coding	2
16	CSNK2A2	Casein Kinase 2 Alpha 2	Protein Coding	2
17	CSNK2B	Casein Kinase 2 Beta	Protein Coding	2
18	CTBP1	C-Terminal Binding Protein 1	Protein Coding	2
19	CTNNB1	Catenin Beta 1	Protein Coding	2
20	DVL1	Dishevelled Segment Polarity Protein 1	Protein Coding	2
21	DVL2	Dishevelled Segment Polarity Protein 2	Protein Coding	2
22	DVL3	Dishevelled Segment Polarity Protein 3	Protein Coding	2
23	EP300	EP300 Lysine Acetyltransferase	Protein Coding	2
24	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	2
25	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	2
26	DKK1	Dickkopf Wnt Signaling Pathway Inhibitor 1	Protein Coding	2
27	HECW1	HECT, C2 And WW Domain Containing E3 Ubiquitin Protein Ligase 1	Protein Coding	2
28	FRAT2	FRAT Regulator Of Wnt Signaling Pathway 2	Protein Coding	2
29	FZD2	Frizzled Class Receptor 2	Protein Coding	2
30	H2BC1	H2B Clustered Histone 1	Protein Coding	2
31	CBY1	Chibby 1, Beta Catenin Antagonist	Protein Coding	2
32	PYGO1	Pygopus Family PHD Finger 1	Protein Coding	2
33	DKK4	Dickkopf Wnt Signaling Pathway Inhibitor 4	Protein Coding	2
34	DKK2	Dickkopf Wnt Signaling Pathway Inhibitor 2	Protein Coding	2
35	BCL9L	BCL9 Like	Protein Coding	2
36	RSPO1	R-Spondin 1	Protein Coding	2
37	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	2
38	H2AC8	H2A Clustered Histone 8	Protein Coding	2
39	H2AC7	H2A Clustered Histone 7	Protein Coding	2
40	H2AX	H2A.X Variant Histone	Protein Coding	2
41	H2BC5	H2B Clustered Histone 5	Protein Coding	2
42	H2BC3	H2B Clustered Histone 3	Protein Coding	2
43	H3-3A	H3.3 Histone A	Protein Coding	2
44	H3-3B	H3.3 Histone B	Protein Coding	2
45	HDAC1	Histone Deacetylase 1	Protein Coding	2
46	APC	APC Regulator Of Wnt Signaling Pathway	Protein Coding	2
47	H3C15	H3 Clustered Histone 15	Protein Coding	2
48	RSPO2	R-Spondin 2	Protein Coding	2
49	RSPO4	R-Spondin 4	Protein Coding	2
50	LRP6	LDL Receptor Related Protein 6	Protein Coding	2
51	LRP5	LDL Receptor Related Protein 5	Protein Coding	2
52	MEN1	Menin 1	Protein Coding	2
53	CCDC88C	Coiled-Coil And HOOK Domain Protein 88C	Protein Coding	2
54	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	2
55	H2AB1	H2A.B Variant Histone 1	Protein Coding	2
56	SOST	Sclerostin	Protein Coding	2
57	LEF1	Lymphoid Enhancer Binding Factor 1	Protein Coding	2
58	DACT1	Dishevelled Binding Antagonist Of Beta Catenin 1	Protein Coding	2
59	H2BC12L	H2B Clustered Histone 12 Like	Protein Coding	2
60	WNT4	Wnt Family Member 4	Protein Coding	2
61	RNF43	Ring Finger Protein 43	Protein Coding	2
62	PPP2CA	Protein Phosphatase 2 Catalytic Subunit Alpha	Protein Coding	2
63	PPP2CB	Protein Phosphatase 2 Catalytic Subunit Beta	Protein Coding	2
64	PPP2R1A	Protein Phosphatase 2 Scaffold Subunit Aalpha	Protein Coding	2
65	PPP2R1B	Protein Phosphatase 2 Scaffold Subunit Abeta	Protein Coding	2
66	PPP2R5A	Protein Phosphatase 2 Regulatory Subunit B''Alpha	Protein Coding	2
67	PPP2R5B	Protein Phosphatase 2 Regulatory Subunit B''Beta	Protein Coding	2
68	PPP2R5C	Protein Phosphatase 2 Regulatory Subunit B''Gamma	Protein Coding	2
69	PPP2R5D	Protein Phosphatase 2 Regulatory Subunit B''Delta	Protein Coding	2
70	PPP2R5E	Protein Phosphatase 2 Regulatory Subunit B''Epsilon	Protein Coding	2
71	LGR4	Leucine Rich Repeat Containing G Protein-Coupled Receptor 4	Protein Coding	2
72	H4C15	H4 Clustered Histone 15	Protein Coding	2
73	SOX6	SRY-Box Transcription Factor 6	Protein Coding	2
74	H2AJ	H2A.J Histone	Protein Coding	2
75	PSMA1	Proteasome 20S Subunit Alpha 1	Protein Coding	2
76	PSMA2	Proteasome 20S Subunit Alpha 2	Protein Coding	2
77	PSMA3	Proteasome 20S Subunit Alpha 3	Protein Coding	2
78	PSMA4	Proteasome 20S Subunit Alpha 4	Protein Coding	2
79	PSMA5	Proteasome 20S Subunit Alpha 5	Protein Coding	2
80	PSMA6	Proteasome 20S Subunit Alpha 6	Protein Coding	2
81	PSMA7	Proteasome 20S Subunit Alpha 7	Protein Coding	2
82	PSMB1	Proteasome 20S Subunit Beta 1	Protein Coding	2
83	PSMB2	Proteasome 20S Subunit Beta 2	Protein Coding	2
84	PSMB3	Proteasome 20S Subunit Beta 3	Protein Coding	2
85	PSMB4	Proteasome 20S Subunit Beta 4	Protein Coding	2
86	PSMB5	Proteasome 20S Subunit Beta 5	Protein Coding	2
87	PSMB6	Proteasome 20S Subunit Beta 6	Protein Coding	2
88	PSMB7	Proteasome 20S Subunit Beta 7	Protein Coding	2
89	CTNNBIP1	Catenin Beta Interacting Protein 1	Protein Coding	2
90	PSMC1	Proteasome 26S Subunit, ATPase 1	Protein Coding	2
91	PSMC2	Proteasome 26S Subunit, ATPase 2	Protein Coding	2
92	PSMC3	Proteasome 26S Subunit, ATPase 3	Protein Coding	2
93	PSMC4	Proteasome 26S Subunit, ATPase 4	Protein Coding	2
94	PSMC5	Proteasome 26S Subunit, ATPase 5	Protein Coding	2
95	PSMC6	Proteasome 26S Subunit, ATPase 6	Protein Coding	2
96	PSMD1	Proteasome 26S Subunit, Non-ATPase 1	Protein Coding	2
97	PSMD2	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 2	Protein Coding	2
98	PSMD3	Proteasome 26S Subunit, Non-ATPase 3	Protein Coding	2
99	PSMD7	Proteasome 26S Subunit, Non-ATPase 7	Protein Coding	2
100	PSMD8	Proteasome 26S Subunit, Non-ATPase 8	Protein Coding	2
101	PSMD11	Proteasome 26S Subunit, Non-ATPase 11	Protein Coding	2
102	PSMD12	Proteasome 26S Subunit, Non-ATPase 12	Protein Coding	2
103	PSMD13	Proteasome 26S Subunit, Non-ATPase 13	Protein Coding	2
104	CHD8	Chromodomain Helicase DNA Binding Protein 8	Protein Coding	2
105	RBBP5	RB Binding Protein 5, Histone Lysine Methyltransferase Complex Subunit	Protein Coding	2
106	KLHL12	Kelch Like Family Member 12	Protein Coding	2
107	LGR6	Leucine Rich Repeat Containing G Protein-Coupled Receptor 6	Protein Coding	2
108	BCL9	BCL9 Transcription Coactivator	Protein Coding	2
109	RPS27A	Ribosomal Protein S27a	Protein Coding	2
110	RYK	Receptor Like Tyrosine Kinase	Protein Coding	2
111	SFRP1	Secreted Frizzled Related Protein 1	Protein Coding	2
112	SFRP2	Secreted Frizzled Related Protein 2	Protein Coding	2
113	SOX17	SRY-Box Transcription Factor 17	Protein Coding	2
114	SMURF2	SMAD Specific E3 Ubiquitin Protein Ligase 2	Protein Coding	2
115	H3C13	H3 Clustered Histone 13	Protein Coding	2
116	SMARCA4	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 4	Protein Coding	2
117	SOX2	SRY-Box Transcription Factor 2	Protein Coding	2
118	SOX3	SRY-Box Transcription Factor 3	Protein Coding	2
119	SOX4	SRY-Box Transcription Factor 4	Protein Coding	2
120	SOX9	SRY-Box Transcription Factor 9	Protein Coding	2
121	SRY	Sex Determining Region Y	Protein Coding	2
122	TCF7	Transcription Factor 7	Protein Coding	2
123	TCF7L2	Transcription Factor 7 Like 2	Protein Coding	2
124	TERT	Telomerase Reverse Transcriptase	Protein Coding	2
125	TLE1	TLE Family Member 1, Transcriptional Corepressor	Protein Coding	2
126	TLE2	TLE Family Member 2, Transcriptional Corepressor	Protein Coding	2
127	TLE3	TLE Family Member 3, Transcriptional Corepressor	Protein Coding	2
128	TLE4	TLE Family Member 4, Transcriptional Corepressor	Protein Coding	2
129	H2AC19	H2A Clustered Histone 19	Protein Coding	2
130	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	2
131	UBB	Ubiquitin B	Protein Coding	2
132	UBC	Ubiquitin C	Protein Coding	2
133	WNT1	Wnt Family Member 1	Protein Coding	2
134	WNT3	Wnt Family Member 3	Protein Coding	2
135	WNT5A	Wnt Family Member 5A	Protein Coding	2
136	WNT8A	Wnt Family Member 8A	Protein Coding	2
137	WNT8B	Wnt Family Member 8B	Protein Coding	2
138	WNT9A	Wnt Family Member 9A	Protein Coding	2
139	XPO1	Exportin 1	Protein Coding	2
140	YWHAZ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta	Protein Coding	2
141	FZD5	Frizzled Class Receptor 5	Protein Coding	2
142	KREMEN2	Kringle Containing Transmembrane Protein 2	Protein Coding	2
143	CDC73	Cell Division Cycle 73	Protein Coding	2
144	SEM1	SEM1 26S Proteasome Subunit	Protein Coding	2
145	TNKS2	Tankyrase 2	Protein Coding	2
146	KMT2D	Lysine Methyltransferase 2D	Protein Coding	2
147	RNF146	Ring Finger Protein 146	Protein Coding	2
148	H3-4	H3.4 Histone, Cluster Member	Protein Coding	2
149	H4C9	H4 Clustered Histone 9	Protein Coding	2
150	TRRAP	Transformation/Transcription Domain Associated Protein	Protein Coding	2
151	AXIN1	Axin 1	Protein Coding	2
152	AXIN2	Axin 2	Protein Coding	2
153	FZD1	Frizzled Class Receptor 1	Protein Coding	2
154	FZD4	Frizzled Class Receptor 4	Protein Coding	2
155	FZD6	Frizzled Class Receptor 6	Protein Coding	2
156	FZD8	Frizzled Class Receptor 8	Protein Coding	2
157	H2AC14	H2A Clustered Histone 14	Protein Coding	2
158	H2AC6	H2A Clustered Histone 6	Protein Coding	2
159	H2AC4	H2A Clustered Histone 4	Protein Coding	2
160	H2AC18	H2A Clustered Histone 18	Protein Coding	2
161	H2AC20	H2A Clustered Histone 20	Protein Coding	2
162	H2BC8	H2B Clustered Histone 8	Protein Coding	2
163	H2BC13	H2B Clustered Histone 13	Protein Coding	2
164	H2BC15	H2B Clustered Histone 15	Protein Coding	2
165	H2BC14	H2B Clustered Histone 14	Protein Coding	2
166	H2BC7	H2B Clustered Histone 7	Protein Coding	2
167	TCF7L1	Transcription Factor 7 Like 1	Protein Coding	2
168	H2BC6	H2B Clustered Histone 6	Protein Coding	2
169	H2BC9	H2B Clustered Histone 9	Protein Coding	2
170	H2BC10	H2B Clustered Histone 10	Protein Coding	2
171	H2BC4	H2B Clustered Histone 4	Protein Coding	2
172	H2BC17	H2B Clustered Histone 17	Protein Coding	2
173	H2BC21	H2B Clustered Histone 21	Protein Coding	2
174	H3C1	H3 Clustered Histone 1	Protein Coding	2
175	H3C4	H3 Clustered Histone 4	Protein Coding	2
176	H3C3	H3 Clustered Histone 3	Protein Coding	2
177	H3C6	H3 Clustered Histone 6	Protein Coding	2
178	H3C11	H3 Clustered Histone 11	Protein Coding	2
179	H3C8	H3 Clustered Histone 8	Protein Coding	2
180	H3C12	H3 Clustered Histone 12	Protein Coding	2
181	H3C10	H3 Clustered Histone 10	Protein Coding	2
182	H3C2	H3 Clustered Histone 2	Protein Coding	2
183	H4C1	H4 Clustered Histone 1	Protein Coding	2
184	SOX7	SRY-Box Transcription Factor 7	Protein Coding	2
185	H4C4	H4 Clustered Histone 4	Protein Coding	2
186	H4C6	H4 Clustered Histone 6	Protein Coding	2
187	H4C12	H4 Clustered Histone 12	Protein Coding	2
188	H4C11	H4 Clustered Histone 11	Protein Coding	2
189	H4C3	H4 Clustered Histone 3	Protein Coding	2
190	H4C8	H4 Clustered Histone 8	Protein Coding	2
191	H4C2	H4 Clustered Histone 2	Protein Coding	2
192	H4C5	H4 Clustered Histone 5	Protein Coding	2
193	H4C13	H4 Clustered Histone 13	Protein Coding	2
194	H4C14	H4 Clustered Histone 14	Protein Coding	2
195	PIP5K1B	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Beta	Protein Coding	2
196	KREMEN1	Kringle Containing Transmembrane Protein 1	Protein Coding	2
197	ZNRF3	Zinc And Ring Finger 3	Protein Coding	2
198	CUL3	Cullin 3	Protein Coding	2
199	RSPO3	R-Spondin 3	Protein Coding	2
200	H2BC12	H2B Clustered Histone 12	Protein Coding	2
201	LGR5	Leucine Rich Repeat Containing G Protein-Coupled Receptor 5	Protein Coding	2
202	CAV1	Caveolin 1	Protein Coding	2
203	RUVBL1	RuvB Like AAA ATPase 1	Protein Coding	2
204	RUNX3	RUNX Family Transcription Factor 3	Protein Coding	2
205	TNKS	Tankyrase	Protein Coding	2
206	BTRC	Beta-Transducin Repeat Containing E3 Ubiquitin Protein Ligase	Protein Coding	2
207	H3C7	H3 Clustered Histone 7	Protein Coding	2
208	H2BC11	H2B Clustered Histone 11	Protein Coding	2
209	WNT3A	Wnt Family Member 3A	Protein Coding	2
210	ASH2L	ASH2 Like, Histone Lysine Methyltransferase Complex Subunit	Protein Coding	2
211	PYGO2	Pygopus Family PHD Finger 2	Protein Coding	2
212	USP8	Ubiquitin Specific Peptidase 8	Protein Coding	2
213	H2AZ2	H2A.Z Variant Histone 2	Protein Coding	2
214	SOX13	SRY-Box Transcription Factor 13	Protein Coding	2
215	USP34	Ubiquitin Specific Peptidase 34	Protein Coding	2
216	PSMD6	Proteasome 26S Subunit, Non-ATPase 6	Protein Coding	2
217	RBX1	Ring-Box 1	Protein Coding	2
218	GNB5	G Protein Subunit Beta 5	Protein Coding	1
219	AP2M1	Adaptor Related Protein Complex 2 Subunit Mu 1	Protein Coding	1
220	AP2S1	Adaptor Related Protein Complex 2 Subunit Sigma 1	Protein Coding	1
221	CLTA	Clathrin Light Chain A	Protein Coding	1
222	CLTB	Clathrin Light Chain B	Protein Coding	1
223	CLTC	Clathrin Heavy Chain	Protein Coding	1
224	PRICKLE1	Prickle Planar Cell Polarity Protein 1	Protein Coding	1
225	CTBP2	C-Terminal Binding Protein 2	Protein Coding	1
226	AP2A1	Adaptor Related Protein Complex 2 Subunit Alpha 1	Protein Coding	1
227	AP2A2	Adaptor Related Protein Complex 2 Subunit Alpha 2	Protein Coding	1
228	AP2B1	Adaptor Related Protein Complex 2 Subunit Beta 1	Protein Coding	1
229	TLE5	TLE Family Member 5, Transcriptional Modulator	Protein Coding	1
230	AGO3	Argonaute RISC Catalytic Component 3	Protein Coding	1
231	AGO4	Argonaute RISC Component 4	Protein Coding	1
232	DAAM1	Dishevelled Associated Activator Of Morphogenesis 1	Protein Coding	1
233	TNRC6B	Trinucleotide Repeat Containing Adaptor 6B	Protein Coding	1
234	PLCB1	Phospholipase C Beta 1	Protein Coding	1
235	SCRIB	Scribble Planar Cell Polarity Protein	Protein Coding	1
236	AGO1	Argonaute RISC Component 1	Protein Coding	1
237	AGO2	Argonaute RISC Catalytic Component 2	Protein Coding	1
238	TNRC6A	Trinucleotide Repeat Containing Adaptor 6A	Protein Coding	1
239	GNAO1	G Protein Subunit Alpha O1	Protein Coding	1
240	GNAT2	G Protein Subunit Alpha Transducin 2	Protein Coding	1
241	GNB1	G Protein Subunit Beta 1	Protein Coding	1
242	GNB2	G Protein Subunit Beta 2	Protein Coding	1
243	GNB3	G Protein Subunit Beta 3	Protein Coding	1
244	GNG3	G Protein Subunit Gamma 3	Protein Coding	1
245	GNG4	G Protein Subunit Gamma 4	Protein Coding	1
246	GNG5	G Protein Subunit Gamma 5	Protein Coding	1
247	GNG7	G Protein Subunit Gamma 7	Protein Coding	1
248	GNG10	G Protein Subunit Gamma 10	Protein Coding	1
249	GNG11	G Protein Subunit Gamma 11	Protein Coding	1
250	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	1
251	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	1
252	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	1
253	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	1
254	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	1
255	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	1
256	RHOA	Ras Homolog Family Member A	Protein Coding	1
257	ARRB2	Arrestin Beta 2	Protein Coding	1
258	MOV10	Mov10 RNA Helicase	Protein Coding	1
259	NFATC1	Nuclear Factor Of Activated T Cells 1	Protein Coding	1
260	ROR1	Receptor Tyrosine Kinase Like Orphan Receptor 1	Protein Coding	1
261	ROR2	Receptor Tyrosine Kinase Like Orphan Receptor 2	Protein Coding	1
262	PARD6A	Par-6 Family Cell Polarity Regulator Alpha	Protein Coding	1
263	TMED5	Transmembrane P24 Trafficking Protein 5	Protein Coding	1
264	WNT16	Wnt Family Member 16	Protein Coding	1
265	PDE6A	Phosphodiesterase 6A	Protein Coding	1
266	PDE6G	Phosphodiesterase 6G	Protein Coding	1
267	PDE6B	Phosphodiesterase 6B	Protein Coding	1
268	VPS29	VPS29 Retromer Complex Component	Protein Coding	1
269	NLK	Nemo Like Kinase	Protein Coding	1
270	GNG13	G Protein Subunit Gamma 13	Protein Coding	1
271	PFN1	Profilin 1	Protein Coding	1
272	PLCB2	Phospholipase C Beta 2	Protein Coding	1
273	PLCB3	Phospholipase C Beta 3	Protein Coding	1
274	GNG2	G Protein Subunit Gamma 2	Protein Coding	1
275	ZRANB1	Zinc Finger RANBP2-Type Containing 1	Protein Coding	1
276	PPP3CA	Protein Phosphatase 3 Catalytic Subunit Alpha	Protein Coding	1
277	PPP3CB	Protein Phosphatase 3 Catalytic Subunit Beta	Protein Coding	1
278	PPP3R1	Protein Phosphatase 3 Regulatory Subunit B, Alpha	Protein Coding	1
279	VPS35	VPS35 Retromer Complex Component	Protein Coding	1
280	PRKCA	Protein Kinase C Alpha	Protein Coding	1
281	PRKCB	Protein Kinase C Beta	Protein Coding	1
282	PRKCG	Protein Kinase C Gamma	Protein Coding	1
283	PRKG1	Protein Kinase CGMP-Dependent 1	Protein Coding	1
284	PRKG2	Protein Kinase CGMP-Dependent 2	Protein Coding	1
285	GNG12	G Protein Subunit Gamma 12	Protein Coding	1
286	SMURF1	SMAD Specific E3 Ubiquitin Protein Ligase 1	Protein Coding	1
287	VANGL2	VANGL Planar Cell Polarity Protein 2	Protein Coding	1
288	TNRC6C	Trinucleotide Repeat Containing Adaptor 6C	Protein Coding	1
289	RAC1	Rac Family Small GTPase 1	Protein Coding	1
290	RAC2	Rac Family Small GTPase 2	Protein Coding	1
291	RAC3	Rac Family Small GTPase 3	Protein Coding	1
292	GNB4	G Protein Subunit Beta 4	Protein Coding	1
293	PORCN	Porcupine O-Acyltransferase	Protein Coding	1
294	SKP1	S-Phase Kinase Associated Protein 1	Protein Coding	1
295	MAP3K7	Mitogen-Activated Protein Kinase Kinase Kinase 7	Protein Coding	1
296	WNT2	Wnt Family Member 2	Protein Coding	1
297	WNT6	Wnt Family Member 6	Protein Coding	1
298	WNT7A	Wnt Family Member 7A	Protein Coding	1
299	WNT7B	Wnt Family Member 7B	Protein Coding	1
300	WNT10B	Wnt Family Member 10B	Protein Coding	1
301	WNT11	Wnt Family Member 11	Protein Coding	1
302	WNT2B	Wnt Family Member 2B	Protein Coding	1
303	WNT9B	Wnt Family Member 9B	Protein Coding	1
304	FZD3	Frizzled Class Receptor 3	Protein Coding	1
305	WLS	Wnt Ligand Secretion Mediator	Protein Coding	1
306	CALM1	Calmodulin 1	Protein Coding	1
307	WNT10A	Wnt Family Member 10A	Protein Coding	1
308	CALM2	Calmodulin 2	Protein Coding	1
309	CALM3	Calmodulin 3	Protein Coding	1
310	WNT5B	Wnt Family Member 5B	Protein Coding	1
311	CAMK2A	Calcium/Calmodulin Dependent Protein Kinase II Alpha	Protein Coding	1
312	FZD7	Frizzled Class Receptor 7	Protein Coding	1
313	CUL1	Cullin 1	Protein Coding	1
314	SNX3	Sorting Nexin 3	Protein Coding	1
315	GNG8	G Protein Subunit Gamma 8	Protein Coding	1
316	VPS26A	VPS26 Retromer Complex Component A	Protein Coding	1

Disorders associated with Signaling by WNT SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Robinow syndrome, autosomal recessive 1	Enrichment	DVL1, DVL3, FZD2, ROR2, WNT5A	8.18
2	Autosomal recessive robinow syndrome	Enrichment	DVL1, DVL3, FZD2, ROR2, WNT5A	7.41
3	Robinow syndrome, autosomal dominant 1	Enrichment	DVL1, DVL3, FZD2, WNT5A	7.20
4	Autosomal dominant robinow syndrome	Enrichment	DVL1, DVL3, FZD2, WNT5A	7.20
5	Osteoporosis, juvenile	Enrichment	DKK1, WNT1, WNT3A	5.39
6	Tessadori-bicknell-van haaften neurodevelopmental syndrome 4	Enrichment	H2BC12, H4C1, H4C9	5.39
7	Complex neurodevelopmental disorder	Enrichment	AGO1, AGO2, CSNK2A1, CUL3, GNB2, H4C3, H4C5, H4C9, PPP2CA, PSMD12, RAC3, TCF7L2, TNRC6B	5.20
8	Exudative vitreoretinopathy 1	Enrichment	CTNNB1, FZD4, LRP5	4.40
9	Robinow syndrome, autosomal dominant 2	Enrichment	DVL1, DVL3, FZD2	4.40
10	Nonsyndromic 46,xx testicular disorders/differences of sex development	Enrichment	SOX3, SOX9, SRY	4.40
11	Adrenocortical carcinoma	Enrichment	CTNNB1, TERT, ZNRF3	4.11
12	Polycystic liver disease	Enrichment	CTNNB1, LRP5, LRP6, RUVBL1	3.89
13	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1, LRP5, LRP6, RUVBL1	3.89
14	Exudative vitreoretinopathy	Enrichment	CTNNB1, FZD4, LRP5	3.67
15	Van buchem disease	Enrichment	LRP5, SOST	3.59
16	Osteopathia striata with cranial sclerosis	Enrichment	AMER1, CTNNB1	3.59
17	Hyperparathyroidism 1	Enrichment	CDC73, MEN1	3.59
18	Robinow syndrome, autosomal dominant 3	Enrichment	DVL3, FZD2	3.59
19	Tessadori-bicknell-van haaften neurodevelopmental syndrome 1	Enrichment	H4C1, H4C3	3.59
20	Tessadori-bicknell-van haaften neurodevelopmental syndrome 2	Enrichment	H4C1, H4C11	3.59
21	Bryant-li-bhoj neurodevelopmental syndrome 2	Enrichment	H3-3A, H3-3B	3.59
22	Rare genetic intellectual disability	Enrichment	CHD8, CREBBP, EP300, GNAO1	3.49
23	Hepatocellular carcinoma	Enrichment	APC, AXIN1, CTNNB1, TERT	3.43
24	Colorectal cancer	Enrichment	AKT1, AMER1, APC, AXIN2, CTNNB1, EP300, SOX9	3.32
25	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	3.19
26	Isolated split hand-split foot malformation	Enrichment	BTRC, SEM1, WNT10B	3.19
27	Desmoid disease, hereditary	Enrichment	APC, CTNNB1	3.12
28	46,xx sex reversal 1	Enrichment	SOX9, SRY	3.12
29	Tessadori-bicknell-van haaften neurodevelopmental syndrome 3	Enrichment	H4C1, H4C5	3.12
30	Desmoid tumor	Enrichment	APC, CTNNB1	3.12
31	Parathyroid adenoma	Enrichment	CDC73, MEN1	3.12
32	Tetraamelia syndrome	Enrichment	RSPO2, WNT3	3.12
33	Familial isolated hyperparathyroidism	Enrichment	CDC73, MEN1	3.12
34	Autosomal dominant non-syndromic intellectual disability	Enrichment	CAMK2A, CLTC, CSNK2B, GNB1, PPP3CA, YWHAZ	2.99
35	Retinopathy of prematurity	Enrichment	FZD4, LRP5	2.82
36	Craniopharyngioma	Enrichment	APC, CTNNB1	2.82
37	Tooth agenesis	Enrichment	AXIN2, LRP6, WNT10A, WNT10B	2.82
38	Neural tube defects	Enrichment	DACT1, SCRIB, VANGL2	2.52
39	Lung sarcomatoid carcinoma	Enrichment	KRAS, TERT	2.50
40	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	2.44
41	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	2.44
42	Hepatoblastoma	Enrichment	APC, CTNNB1, TERT	2.36
43	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3, ITPR3	2.31
44	Multiple endocrine neoplasia, type i	Enrichment	CDC73, MEN1	2.29
45	Cleft palate, isolated	Enrichment	AMER1, GNB1, SMARCA4	2.18
46	Glioma susceptibility 1	Enrichment	H3-3A, H3C1	2.17
47	Breast adenocarcinoma	Enrichment	AKT1, KRAS	2.12
48	Charge syndrome	Enrichment	EP300, KMT2D	2.07
49	Adult hepatocellular carcinoma	Enrichment	AXIN1, CTNNB1	2.07
50	Noonan syndrome 3	Enrichment	CLTC, KRAS	1.98
51	Gallbladder cancer	Enrichment	CTNNB1, KRAS	1.98
52	Macs syndrome	Enrichment	PORCN, SOX2, WNT7B	1.97
53	46,xy complete gonadal dysgenesis	Enrichment	SOX9, SRY	1.89
54	Heritable pulmonary arterial hypertension	Enrichment	CAV1, SOX17	1.89
55	Septooptic dysplasia	Enrichment	SOX2, SOX3	1.82
56	Meningioma	Enrichment	AKT1, TERT	1.82
57	Chiari malformation type i	Enrichment	DKK1	1.80
58	Proteus syndrome	Enrichment	AKT1	1.80
59	Endosteal hyperostosis, autosomal dominant	Enrichment	LRP5	1.80
60	Craniodiaphyseal dysplasia, autosomal dominant	Enrichment	SOST	1.80
61	Nail disorder, nonsyndromic congenital, 1	Enrichment	FZD6	1.80
62	Mullerian aplasia and hyperandrogenism	Enrichment	WNT4	1.80
63	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	1.80
64	Panhypopituitarism, x-linked	Enrichment	SOX3	1.80
65	Bone mineral density quantitative trait locus 1	Enrichment	LRP5	1.80
66	Exudative vitreoretinopathy 4	Enrichment	LRP5	1.80
67	Sclerosteosis 1	Enrichment	SOST	1.80
68	Oligodontia-colorectal cancer syndrome	Enrichment	AXIN2	1.80
69	Branchial cleft anomalies	Enrichment	KMT2D	1.80
70	Lipodystrophy, congenital generalized, type 3	Enrichment	CAV1	1.80
71	46,xx sex reversal with dysgenesis of kidneys, adrenals, and lungs	Enrichment	WNT4	1.80
72	Parathyroid carcinoma	Enrichment	CDC73	1.80
73	Omodysplasia 2	Enrichment	FZD2	1.80
74	Hyperparathyroidism 2 with jaw tumors	Enrichment	CDC73	1.80
75	Pseudohypoaldosteronism, type iie	Enrichment	CUL3	1.80
76	Tooth agenesis, selective, 7	Enrichment	LRP6	1.80
77	Sessile serrated polyposis cancer syndrome	Enrichment	RNF43	1.80
78	Caudal duplication anomaly	Enrichment	AXIN1	1.80
79	Vesicoureteral reflux 3	Enrichment	SOX17	1.80
80	Ectodermal dysplasia 13, hair/tooth type	Enrichment	KREMEN1	1.80
81	Bone mineral density quantitative trait locus 17	Enrichment	LGR4	1.80
82	Pulmonary hypertension, primary, 3	Enrichment	CAV1	1.80
83	Ectodermal dysplasia 17 with or without limb malformations	Enrichment	LEF1	1.80
84	Exudative vitreoretinopathy 8	Enrichment	LRP6	1.80
85	Intellectual developmental disorder with speech delay and dysmorphic facies	Enrichment	SOX4	1.80
86	Neurodevelopmental disorder with microcephaly, hypotonia, and absent language	Enrichment	PSMB1	1.80
87	46,xy sex reversal 10	Enrichment	SOX9	1.80
88	Humerofemoral hypoplasia with radiotibial ray deficiency	Enrichment	RSPO2	1.80
89	Tolchin-le caignec syndrome	Enrichment	SOX6	1.80
90	Houge-janssens syndrome 4	Enrichment	PPP2R5C	1.80
91	46,xx sex reversal 2	Enrichment	SOX9	1.80
92	Stankiewicz-isidor syndrome	Enrichment	PSMD12	1.80
93	Adrenal cortical adenoma	Enrichment	MEN1	1.80
94	Intellectual developmental disorder, x-linked, with panhypopituitarism	Enrichment	SOX3	1.80
95	Palmoplantar hyperkeratosis with squamous cell carcinoma of skin and 46,xx sex reversal	Enrichment	RSPO1	1.80
96	Osteoporosis-pseudoglioma syndrome	Enrichment	LRP5	1.80
97	Lipodystrophy, familial partial, type 7	Enrichment	CAV1	1.80
98	Coronary artery disease, autosomal dominant 2	Enrichment	LRP6	1.80
99	Bone mineral density quantitative trait locus 16	Enrichment	WNT1	1.80
100	Houge-janssens syndrome 2	Enrichment	PPP2R1A	1.80
101	Deafness, cataract, impaired intellectual development, and polyneuropathy	Enrichment	PSMC3	1.80
102	Spinocerebellar ataxia 40	Enrichment	CCDC88C	1.80
103	Polycystic liver disease 4 with or without kidney cysts	Enrichment	LRP5	1.80
104	Cowden syndrome 6	Enrichment	AKT1	1.80
105	Microphthalmia/coloboma 11	Enrichment	FZD5	1.80
106	Cdc73-related disorders	Enrichment	CDC73	1.80
107	Branchial arch abnormalities, choanal atresia, athelia, hearing loss, and hypothyroidism syndrome	Enrichment	KMT2D	1.80
108	Smarca4-deficient sarcoma of thorax	Enrichment	SMARCA4	1.80
109	Ovarian small cell carcinoma	Enrichment	SMARCA4	1.80
110	Deafness, autosomal dominant 75	Enrichment	TRRAP	1.80
111	Neurodevelopmental disorder with or without autism or seizures	Enrichment	CUL3	1.80
112	Bryant-li-bhoj neurodevelopmental syndrome 1	Enrichment	H3-3A	1.80
113	Okur-chung neurodevelopmental syndrome	Enrichment	CSNK2A1	1.80
114	Townes-brocks syndrome 2	Enrichment	DACT1	1.80
115	Tetraamelia syndrome 2	Enrichment	RSPO2	1.80
116	Menke-hennekam syndrome 1	Enrichment	CREBBP	1.80
117	Hyperplastic polyposis syndrome	Enrichment	RNF43	1.80
118	Developmental delay with or without dysmorphic facies and autism	Enrichment	TRRAP	1.80
119	Autosomal recessive dyskeratosis congenita 4	Enrichment	TERT	1.80
120	Craniometadiaphyseal osteosclerosis with hip dysplasia	Enrichment	AXIN1	1.80
121	Craniorachischisis	Enrichment	DACT1	1.80
122	Adenoid ameloblastoma	Enrichment	CTNNB1	1.80
123	45,x/46,xy mixed gonadal dysgenesis	Enrichment	SRY	1.80
124	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	1.80
125	Autosomal recessive spastic paraplegia type 59	Enrichment	USP8	1.80
126	Craniodigital syndrome and intellectual disability syndrome	Enrichment	CSNK2B	1.80
127	Lrp5-related primary osteoporosis	Enrichment	LRP5	1.80
128	Pulmonary hypertension, primary, 7	Enrichment	SOX17	1.80
129	Palmoplantar keratoderma-xx sex reversal-predisposition to squamous cell carcinoma syndrome	Enrichment	RSPO1	1.80
130	Familial adenomatous polyposis	Enrichment	APC	1.80
131	Adrenal adenoma	Enrichment	MEN1	1.80
132	Menke-hennekam syndrome	Enrichment	CREBBP	1.80
133	Gardner syndrome	Enrichment	APC	1.80
134	Osteosclerosis-developmental delay-craniosynostosis syndrome	Enrichment	LRP5	1.80
135	5q22 microdeletion syndrome	Enrichment	APC	1.80
136	Ppp2r1a-related neurodevelopmental disorder	Enrichment	PPP2R1A	1.80
137	Attenuated familial adenomatous polyposis	Enrichment	APC	1.80
138	Microcystic stromal tumor	Enrichment	CTNNB1	1.80
139	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	1.80
140	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1, TNRC6B	1.76
141	Hereditary breast carcinoma	Enrichment	AKT1, APC, CDC73, KRAS	1.72
142	Osteoporosis	Enrichment	LRP5, WNT1	1.69
143	Medulloblastoma	Enrichment	APC, CTNNB1	1.69
144	46,xy partial gonadal dysgenesis	Enrichment	SOX9, SRY	1.69
145	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	1.63
146	Brachydactyly, type b1	Enrichment	ROR2	1.63
147	Cardiospondylocarpofacial syndrome	Enrichment	MAP3K7	1.63
148	Oculoectodermal syndrome	Enrichment	KRAS	1.63
149	Hypocalciuric hypercalcemia, familial, type iii	Enrichment	AP2S1	1.63
150	Microphthalmia, syndromic 8	Enrichment	SNX3	1.63
151	Focal dermal hypoplasia	Enrichment	PORCN	1.63
152	Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis	Enrichment	RAC2	1.63
153	Split-hand/foot malformation 6	Enrichment	WNT10B	1.63
154	Amyotrophic lateral sclerosis 18	Enrichment	PFN1	1.63
155	Tooth agenesis, selective, 8	Enrichment	WNT10B	1.63
156	Retinitis pigmentosa 57	Enrichment	PDE6G	1.63
157	Parkinson disease 17	Enrichment	VPS35	1.63
158	Aortic aneurysm, familial thoracic 8	Enrichment	PRKG1	1.63
159	Neurodevelopmental disorder with involuntary movements	Enrichment	GNAO1	1.63
160	Frontometaphyseal dysplasia 2	Enrichment	MAP3K7	1.63
161	Global developmental delay with speech and behavioral abnormalities	Enrichment	TNRC6B	1.63
162	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	1.63
163	Spondylometaphyseal dysplasia, pagnamenta type	Enrichment	PRKG2	1.63
164	Spondylometaphyseal dysplasia with corneal dystrophy	Enrichment	PLCB3	1.63
165	Deafness, autosomal recessive 108	Enrichment	ROR1	1.63
166	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	1.63
167	Intellectual developmental disorder, autosomal recessive 63	Enrichment	CAMK2A	1.63
168	Developmental and epileptic encephalopathy 91	Enrichment	PPP3CA	1.63
169	Neurodevelopmental disorder with structural brain anomalies and dysmorphic facies	Enrichment	RAC3	1.63
170	Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development	Enrichment	PPP3CA	1.63
171	Diarrhea 9	Enrichment	WNT2B	1.63
172	Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia	Enrichment	RAC2	1.63
173	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	1.63
174	Developmental and epileptic encephalopathy 17	Enrichment	GNAO1	1.63
175	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	1.63
176	Spinocerebellar ataxia 14	Enrichment	PRKCG	1.63
177	Santos syndrome	Enrichment	WNT7A	1.63
178	Long qt syndrome 16	Enrichment	CALM3	1.63
179	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	1.63
180	Retinitis pigmentosa 43	Enrichment	PDE6A	1.63
181	Epilepsy, familial adult myoclonic, 6	Enrichment	TNRC6A	1.63
182	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	1.63
183	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	1.63
184	Sick sinus syndrome 4	Enrichment	GNB2	1.63
185	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	1.63
186	Intellectual developmental disorder, autosomal dominant 53	Enrichment	CAMK2A	1.63
187	Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia	Enrichment	RAC2	1.63
188	Long qt syndrome 15	Enrichment	CALM2	1.63
189	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	1.63
190	Congenital pulmonary airway malformation	Enrichment	KRAS	1.63
191	Infantile lad-like disease due to rac2 deficiency	Enrichment	RAC2	1.63
192	Reticular dysgenesis-like severe combined immunodeficiency	Enrichment	RAC2	1.63
193	Gnao1-related disorder	Enrichment	GNAO1	1.63
194	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	1.63
195	Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome	Enrichment	RAC2	1.63
196	Coffin-siris syndrome 1	Enrichment	SMARCA4, SOX4	1.63
197	Autism	Enrichment	CHD8, CREBBP, KMT2D, TCF7L2	1.55
198	Bladder cancer	Enrichment	CTNNB1, KRAS, TERT	1.53
199	Breast cancer	Enrichment	AKT1, APC, CDC73, GNG3, KRAS	1.52
200	Ectrodactyly and ectodermal dysplasia without cleft lip/palate	Enrichment	LEF1	1.50
201	Burkitt lymphoma	Enrichment	MYC	1.50
202	Campomelic dysplasia	Enrichment	SOX9	1.50
203	Craniodiaphyseal dysplasia	Enrichment	SOST	1.50
204	Pituitary adenoma 4, acth-secreting	Enrichment	USP8	1.50
205	Thumb deformity	Enrichment	CREBBP	1.50
206	Bladder exstrophy and epispadias complex	Enrichment	WNT3	1.50
207	Hypertrichosis, congenital generalized, 2	Enrichment	SOX3	1.50
208	Tetraamelia syndrome 1	Enrichment	WNT3	1.50
209	Rhabdoid tumor predisposition syndrome 2	Enrichment	SMARCA4	1.50
210	Pseudohypoaldosteronism, type i, autosomal dominant	Enrichment	CUL3	1.50
211	Complement component c1s deficiency	Enrichment	KMT2D	1.50
212	Osteogenesis imperfecta, type xv	Enrichment	WNT1	1.50
213	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 1	Enrichment	TERT	1.50
214	Choanal atresia, posterior	Enrichment	KMT2D	1.50
215	Houge-janssens syndrome 1	Enrichment	PPP2R5D	1.50
216	Neurodevelopmental disorder with dysmorphic facies, sleep disturbance, and brain abnormalities	Enrichment	KAT5	1.50
217	Immunodeficiency, common variable, 15	Enrichment	RUVBL1	1.50
218	Birk-aharoni syndrome	Enrichment	PSMC1	1.50
219	Hypotonia, ataxia, developmental delay, and tooth enamel defect syndrome	Enrichment	CTBP1	1.50
220	46,xy sex reversal 1	Enrichment	SRY	1.50
221	Poirier-bienvenu neurodevelopmental syndrome	Enrichment	CSNK2B	1.50
222	Menke-hennekam syndrome 2	Enrichment	EP300	1.50
223	Proteasome-associated autoinflammatory syndrome 3	Enrichment	PSMB4	1.50
224	Sclerosteosis	Enrichment	SOST	1.50
225	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	1.50
226	Rhabdoid tumor predisposition syndrome	Enrichment	SMARCA4	1.50
227	Townes-brocks syndrome	Enrichment	DACT1	1.50
228	Delayed puberty, self-limited	Enrichment	LGR4	1.50
229	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	1.50
230	Split hand-foot malformation	Enrichment	LEF1	1.50
231	Medullary thyroid carcinoma	Enrichment	MEN1	1.50
232	Melanoma, cutaneous malignant 9	Enrichment	TERT	1.50
233	Otosclerosis 12	Enrichment	SMARCA4	1.50
234	Coffin-siris syndrome 4	Enrichment	SMARCA4	1.50
235	Periampullary adenoma	Enrichment	APC	1.50
236	Gastric adenocarcinoma and proximal polyposis of the stomach	Enrichment	APC	1.50
237	Insulinoma	Enrichment	MEN1	1.50
238	Chromosome 2p16.1-p15 deletion syndrome	Enrichment	USP34	1.50
239	14q11.2 microduplication syndrome	Enrichment	CHD8	1.50
240	Idiopathic interstitial pneumonia	Enrichment	TERT	1.50
241	17q24.2 microdeletion syndrome	Enrichment	PSMD12	1.50
242	Houge-janssens syndrome 3	Enrichment	PPP2CA	1.50
243	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.50
244	Teratoma	Enrichment	CTNNB1	1.50
245	Primary mediastinal large b-cell lymphoma	Enrichment	XPO1	1.50
246	Osteosclerosis	Enrichment	LRP5	1.50
247	Bladder exstrophy-epispadias-cloacal exstrophy complex	Enrichment	WNT3	1.50
248	Null pituitary adenoma	Enrichment	MEN1	1.50
249	Silent pituitary adenoma	Enrichment	MEN1	1.50
250	Submucosal cleft palate	Enrichment	UBB	1.50
251	Campomelic dysplasia and related disorders	Enrichment	SOX9	1.50
252	Cleft hard palate	Enrichment	UBB	1.50
253	Gigantism	Enrichment	MEN1	1.50
254	Lung cancer	Enrichment	KMT2D, KRAS, PPP2R1B	1.42
255	Cone-rod dystrophy 6	Enrichment	GNAT2, PDE6B	1.39
256	Myeloma, multiple	Enrichment	CREBBP, H3C1, KMT2D, KRAS	1.39
257	Autism spectrum disorder	Enrichment	CHD8, CSNK2A1, CSNK2B, CUL3, GNB1, TNRC6B	1.38
258	Spinocerebellar ataxia 29	Enrichment	ITPR1	1.34
259	Tooth agenesis, selective, 4	Enrichment	WNT10A	1.34
260	Schopf-schulz-passarge syndrome	Enrichment	WNT10A	1.34
261	Ulna and fibula, absence of, with severe limb deficiency	Enrichment	WNT7A	1.34
262	Odontoonychodermal dysplasia	Enrichment	WNT10A	1.34
263	Premature ovarian failure 3	Enrichment	AGO2	1.34
264	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	1.34
265	Encephalocraniocutaneous lipomatosis	Enrichment	KRAS	1.34
266	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS	1.34
267	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	1.34
268	Fibular aplasia or hypoplasia, femoral bowing, and poly-, syn-, and oligodactyly	Enrichment	WNT7A	1.34
269	Long qt syndrome 14	Enrichment	CALM1	1.34
270	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	1.34
271	Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures	Enrichment	AGO1	1.34
272	Acromesomelic dysplasia 4	Enrichment	PRKG2	1.34
273	Zaki syndrome	Enrichment	WLS	1.34
274	Intellectual developmental disorder, autosomal dominant 60, with seizures	Enrichment	AP2M1	1.34
275	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	1.34
276	Isolated anencephaly	Enrichment	VANGL2	1.34
277	Isolated exencephaly	Enrichment	VANGL2	1.34
278	Cerebral visual impairment	Enrichment	GNB1	1.34
279	Hydrocephalus	Enrichment	CCDC88C, FZD3	1.33
280	Prognathism, mandibular	Enrichment	CSNK2B	1.33
281	Pseudohypoaldosteronism, type iia	Enrichment	CUL3	1.33
282	Proteasome-associated autoinflammatory syndrome 1	Enrichment	PSMB4	1.33
283	Nail disorder, nonsyndromic congenital, 4	Enrichment	RSPO4	1.33
284	Uvula, bifid	Enrichment	UBB	1.33
285	Pituitary hormone deficiency, combined, 2	Enrichment	SOX3	1.33
286	Mullerian duct aplasia, unilateral renal agenesis, and cervicothoracic somite anomalies	Enrichment	WNT4	1.33
287	Osteopetrosis, autosomal dominant 1	Enrichment	LRP5	1.33
288	Cleft soft palate	Enrichment	UBB	1.33
289	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.33
290	Pituitary adenoma 1, multiple types	Enrichment	MEN1	1.33
291	Cenani-lenz syndactyly syndrome	Enrichment	APC	1.33
292	Anus, imperforate	Enrichment	CTNNB1	1.33
293	Neurodevelopmental disorder with progressive spasticity and brain abnormalities	Enrichment	RUVBL1	1.33
294	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.33
295	Tethered spinal cord syndrome	Enrichment	CREBBP	1.33
296	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	MYC	1.33
297	Proteosome-associated autoinflammatory syndrome	Enrichment	PSMB4	1.33
298	Interstitial lung disease	Enrichment	TERT	1.33
299	Nail disease	Enrichment	FZD6	1.33
300	Cellular ependymoma	Enrichment	MEN1	1.33
301	Tanycytic ependymoma	Enrichment	MEN1	1.33
302	Macrocytic anemia	Enrichment	TERT	1.33
303	Papillary ependymoma	Enrichment	MEN1	1.33
304	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.33
305	Familial vesicoureteral reflux	Enrichment	SOX17	1.33
306	Growth hormone secreting pituitary adenoma	Enrichment	MEN1	1.33
307	Aip familial isolated pituitary adenomas	Enrichment	MEN1	1.33
308	Occipital encephalocele	Enrichment	DACT1	1.33
309	Colon adenocarcinoma	Enrichment	APC	1.33
310	Clear cell ependymoma	Enrichment	MEN1	1.33
311	Thyroid hemiagenesis	Enrichment	PSMD3	1.33
312	Apc-associated polyposis conditions	Enrichment	APC	1.33
313	Brittle bone disorder	Enrichment	LRP5, WNT1	1.29
314	Inherited cancer-predisposing syndrome	Enrichment	APC, AXIN2, CDC73, MEN1, SMARCA4	1.22
315	Acyl-coa dehydrogenase, very long-chain, deficiency of	Enrichment	DVL2	1.20
316	Microphthalmia, syndromic 3	Enrichment	SOX2	1.20
317	Microtia-anotia	Enrichment	KMT2D	1.20
318	Pilomatrixoma	Enrichment	CTNNB1	1.20
319	Alazami syndrome	Enrichment	CTNNB1	1.20
320	Intellectual developmental disorder, autosomal dominant 26	Enrichment	KMT2D	1.20
321	Enophthalmos	Enrichment	CSNK2B	1.20
322	Syndactyly	Enrichment	CSNK2B	1.20
323	Intellectual developmental disorder with autism and macrocephaly	Enrichment	CHD8	1.20
324	Orofacial cleft	Enrichment	LRP6	1.20
325	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	YWHAZ	1.20
326	Prolactinoma	Enrichment	MEN1	1.20
327	Eyelid coloboma	Enrichment	FZD5	1.20
328	Primary hyperparathyroidism	Enrichment	MEN1	1.20
329	Vitreoretinopathy	Enrichment	LRP5	1.20
330	Benign ependymoma	Enrichment	MEN1	1.20
331	Orofacial clefting syndrome	Enrichment	LRP6	1.20
332	Lens coloboma	Enrichment	FZD5	1.20
333	Microcephaly	Enrichment	CTNNB1, EP300, GNAO1, GNB1, KMT2D, PSMC3	1.17
334	Night blindness, congenital stationary, autosomal dominant 2	Enrichment	PDE6B	1.17
335	Gillespie syndrome	Enrichment	ITPR1	1.17
336	Microphthalmia, syndromic 9	Enrichment	WNT7B	1.17
337	Tooth agenesis, selective, 2	Enrichment	WNT10A	1.17
338	Retinitis pigmentosa 40	Enrichment	PDE6B	1.17
339	Epilepsy, progressive myoclonic, 1b	Enrichment	PRICKLE1	1.17
340	Intellectual developmental disorder, autosomal dominant 56	Enrichment	CLTC	1.17
341	Frontometaphyseal dysplasia	Enrichment	MAP3K7	1.17
342	Lessel-kreienkamp syndrome	Enrichment	AGO2	1.17
343	Norrie disease	Enrichment	FZD4	1.11
344	Familial adenomatous polyposis 1	Enrichment	APC	1.11
345	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.11
346	Amblyopia	Enrichment	KMT2D	1.11
347	Lymphoma	Enrichment	KMT2D	1.11
348	Congenital ptosis	Enrichment	CHD8	1.11
349	Persistent hyperplastic primary vitreous	Enrichment	FZD4	1.11
350	Coloboma of choroid and retina	Enrichment	FZD5	1.11
351	Diffuse cutaneous systemic sclerosis	Enrichment	CAV1	1.11
352	Idiopathic aplastic anemia	Enrichment	TERT	1.11
353	Ovarian cancer	Enrichment	AKT1, APC, AXIN2, CTNNB1	1.10
354	West syndrome	Enrichment	CSNK1E, GNAO1, PLCB1	1.08
355	Schimmelpenning-feuerstein-mims syndrome	Enrichment	KRAS	1.05
356	Cardiofaciocutaneous syndrome 1	Enrichment	KRAS	1.05
357	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	1.05
358	Ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	WNT10A	1.05
359	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	1.05
360	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	1.05
361	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.05
362	Developmental and epileptic encephalopathy 12	Enrichment	PLCB1	1.05
363	Achromatopsia 4	Enrichment	GNAT2	1.05
364	Cardiofaciocutaneous syndrome	Enrichment	KRAS	1.05
365	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS	1.05
366	Hereditary ataxia	Enrichment	PRKCG	1.05
367	Ectodermal dysplasia	Enrichment	WNT10A	1.05
368	Neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 1	Enrichment	CLTC	1.05
369	Pilocytic astrocytoma	Enrichment	KRAS	1.05
370	Glioma	Enrichment	VPS35	1.05
371	Familial sick sinus syndrome	Enrichment	GNB2	1.05
372	Microphthalmia	Enrichment	SOX2, WNT7B	1.04
373	Dyskeratosis congenita, autosomal dominant 1	Enrichment	TERT	1.04
374	Developmental dysplasia of the hip 1	Enrichment	PSMC3	1.04
375	Coloboma of optic nerve	Enrichment	FZD5	1.04
376	Kabuki syndrome 1	Enrichment	KMT2D	1.04
377	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.04
378	Wolf-hirschhorn syndrome	Enrichment	CTBP1	1.04
379	Split-hand/foot malformation 1	Enrichment	LEF1	1.04
380	Pierre robin syndrome	Enrichment	SOX9	1.04
381	Patent ductus arteriosus	Enrichment	PSMC3	1.04
382	Pulmonary fibrosis	Enrichment	TERT	1.04
383	Limited scleroderma	Enrichment	CAV1	1.04
384	Hoyeraal-hreidarsson syndrome	Enrichment	TERT	1.04
385	Hypertrichosis	Enrichment	CREBBP	1.04
386	46,xy disorder of sex development	Enrichment	SRY	1.04
387	Kidney clear cell sarcoma	Enrichment	TERT	1.04
388	Congenital stationary night blindness	Enrichment	GNB3, PDE6B	1.00
389	Congenital nervous system abnormality	Enrichment	CREBBP, CTNNB1, GNAO1, GNB5, KMT2D	0.99
390	Nervous system disease	Enrichment	CREBBP, CTNNB1, GNAO1, GNB5, KMT2D	0.99
391	Coats disease	Enrichment	FZD4	0.97
392	Gastrointestinal stromal tumor	Enrichment	MEN1	0.97
393	Dyskeratosis congenita, autosomal dominant 2	Enrichment	TERT	0.97
394	Congenital hydrocephalus	Enrichment	CCDC88C	0.97
395	Overgrowth syndrome	Enrichment	CHD8	0.97
396	Albinism, oculocutaneous, type ii	Enrichment	PDE6B	0.95
397	Autosomal recessive hypohidrotic ectodermal dysplasia syndrome	Enrichment	WNT10A	0.95
398	Developmental and epileptic encephalopathy 1	Enrichment	CSNK1E, GNAO1	0.94
399	Neuroblastoma	Enrichment	SMARCA4	0.92
400	Strabismus	Enrichment	GNB1, KMT2D	0.89
401	Hemihyperplasia, isolated	Enrichment	RHOA	0.88
402	Renal dysplasia, cystic	Enrichment	WNT9B	0.88
403	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	0.88
404	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	0.88
405	Inflammatory myofibroblastic tumor	Enrichment	CLTC	0.88
406	Renal hypoplasia	Enrichment	WNT9B	0.88
407	Diarrhea	Enrichment	WNT2B	0.88
408	Lung squamous cell carcinoma	Enrichment	KRAS	0.88
409	Multicystic kidney dysplasia	Enrichment	FZD3	0.88
410	Multicystic dysplastic kidney	Enrichment	FZD3	0.88
411	Tooth agenesis, selective, 1	Enrichment	AXIN2	0.87
412	Primary hyperaldosteronism	Enrichment	USP8	0.87
413	Ventricular septal defect	Enrichment	SMARCA4	0.87
414	Colonic benign neoplasm	Enrichment	APC	0.87
415	Cowden syndrome	Enrichment	AKT1	0.87
416	Type 2 diabetes mellitus	Enrichment	AKT2, TCF7L2	0.84
417	Differentiated thyroid carcinoma	Enrichment	KRAS, TERT	0.84
418	Cat eye syndrome	Enrichment	FZD5	0.83
419	Aplastic anemia	Enrichment	TERT	0.83
420	Polymicrogyria	Enrichment	PSMC3	0.83
421	Nevus, epidermal	Enrichment	KRAS	0.82
422	Capillary malformation-arteriovenous malformation 1	Enrichment	KRAS	0.82
423	Leukemia, chronic myeloid	Enrichment	KRAS	0.82
424	Renal cell carcinoma with mit translocations	Enrichment	CLTC	0.82
425	Pilomyxoid astrocytoma	Enrichment	KRAS	0.82
426	Long qt syndrome	Enrichment	CALM1, CALM2	0.79
427	Non-immune hydrops fetalis	Enrichment	FZD6, KRAS	0.79
428	Nanophthalmos	Enrichment	SOX2	0.79
429	Atrial heart septal defect	Enrichment	SMARCA4	0.79
430	Diabetes mellitus	Enrichment	MEN1	0.79
431	Interatrial communication	Enrichment	SMARCA4	0.79
432	Renal hypodysplasia/aplasia 1	Enrichment	WNT9B	0.76
433	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	0.76
434	Hypothyroidism	Enrichment	GNB1	0.76
435	Choreatic disease	Enrichment	GNAO1	0.76
436	Microphthalmia/coloboma 12	Enrichment	FZD5	0.72
437	Hypercholesterolemia, familial, 1	Enrichment	SMARCA4	0.72
438	Osteogenesis imperfecta, type iv	Enrichment	WNT1	0.72
439	Pulmonary hypertension, primary, 1	Enrichment	SOX17	0.72
440	Nk-cell enteropathy	Enrichment	CUL3	0.72
441	Myoclonic-atonic epilepsy	Enrichment	AP2M1	0.72
442	Developmental and epileptic encephalopathy 14	Enrichment	PLCB1	0.72
443	Renal agenesis, bilateral	Enrichment	WNT9B	0.72
444	Heart disease	Enrichment	CREBBP	0.69
445	Achromatopsia	Enrichment	GNAT2	0.68
446	Coloboma of macula	Enrichment	FZD5	0.67
447	Polydactyly, postaxial, type a1	Enrichment	EP300	0.67
448	Corpus callosum, agenesis of	Enrichment	CREBBP	0.67
449	Osteogenesis imperfecta, type iii	Enrichment	WNT1	0.67
450	Familial hypercholesterolemia	Enrichment	SMARCA4	0.67
451	Isolated corpus callosum agenesis	Enrichment	CREBBP	0.67
452	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP	0.67
453	Male infertility with spermatogenesis disorder	Enrichment	KMT2D	0.67
454	Hydrocephalus, congenital, 1	Enrichment	CCDC88C	0.64
455	Hypertension	Enrichment	MEN1	0.64
456	Leukemia, acute lymphoblastic	Enrichment	GNB1	0.64
457	Myelodysplastic syndrome	Enrichment	GNB1	0.64
458	Lung non-small cell carcinoma	Enrichment	KRAS	0.64
459	Movement disease	Enrichment	GNAO1	0.64
460	Cerebral palsy	Enrichment	GNB1, SMARCA4	0.64
461	Leukemia, acute myeloid	Enrichment	KRAS, TERT	0.62
462	Melanoma, cutaneous malignant 1	Enrichment	TERT	0.62
463	Interstitial lung disease 2	Enrichment	TERT	0.62
464	Dandy-walker syndrome	Enrichment	KMT2D	0.62
465	Juvenile myelomonocytic leukemia	Enrichment	KRAS	0.61
466	Congenital long qt syndrome	Enrichment	ITPR3	0.61
467	Benign epilepsy with centrotemporal spikes	Enrichment	PLCB1, PRICKLE1	0.61
468	Patent foramen ovale	Enrichment	PSMC3	0.60
469	Distal arthrogryposis	Enrichment	FZD3, ROR2	0.59
470	Chronic kidney disease	Enrichment	WNT9B	0.58
471	Diffuse large b-cell lymphoma	Enrichment	CREBBP	0.58
472	Dyskeratosis congenita	Enrichment	TERT	0.58
473	Centralopathic epilepsy	Enrichment	PLCB1, PRICKLE1	0.58
474	Gastric cancer	Enrichment	APC, KRAS	0.58
475	Multiple sclerosis	Enrichment	ITPR1	0.55
476	Myoclonic epilepsy of unverricht and lundborg	Enrichment	PRICKLE1	0.55
477	Lung cancer susceptibility 3	Enrichment	KRAS	0.55
478	Anterior segment dysgenesis	Enrichment	ITPR1	0.53
479	Lynch syndrome	Enrichment	KRAS	0.53
480	Noonan syndrome and noonan-related syndrome	Enrichment	KRAS	0.53
481	Myocardial infarction	Enrichment	PSMA6	0.52
482	Precursor t-cell acute lymphoblastic leukemia	Enrichment	MYC	0.51
483	Scoliosis	Enrichment	CREBBP	0.49
484	Hypertension, essential	Enrichment	GNB3	0.48
485	Sudden infant death syndrome	Enrichment	CALM2	0.48
486	Hydrops fetalis, nonimmune	Enrichment	FZD6	0.47
487	Early infantile developmental and epileptic encephalopathy	Enrichment	GNAO1	0.46
488	Spastic ataxia	Enrichment	CCDC88C, ITPR1	0.45
489	Arteriovenous malformations of the brain	Enrichment	KRAS	0.44
490	Hereditary breast ovarian cancer syndrome	Enrichment	KRAS, MEN1	0.43
491	Hirschsprung disease 1	Enrichment	AXIN2	0.43
492	Undetermined early-onset epileptic encephalopathy	Enrichment	CLTC, PPP3CA	0.42
493	Isolated joubert syndrome	Enrichment	CBY1	0.42
494	Connective tissue disease	Enrichment	SOX9	0.39
495	Attention deficit-hyperactivity disorder	Enrichment	GNB5	0.39
496	Noonan syndrome 1	Enrichment	KRAS	0.38
497	Parkinson disease, late-onset	Enrichment	VPS35	0.36
498	Cone dystrophy	Enrichment	GNAT2	0.36
499	Pancreatic cancer	Enrichment	KRAS	0.35
500	Rasopathy	Enrichment	KRAS	0.34
501	Joubert syndrome 1	Enrichment	CBY1	0.26
502	Dystonia	Enrichment	GNB1	0.25
503	Eye disease	Enrichment	GNAT2	0.25
504	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	TRRAP	0.25
505	Developmental and epileptic encephalopathy	Enrichment	GNAO1	0.24
506	Fetal akinesia deformation sequence 1	Enrichment	ROR2	0.23
507	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	LEO1	0.23
508	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	PRKG1	0.19
509	Leber plus disease	Enrichment	PDE6A, PDE6B	0.19
510	Hereditary retinal dystrophy	Enrichment	FZD4, GNAT2, LRP5, PDE6A, PDE6B, PDE6G	0.17
511	Fundus dystrophy	Enrichment	FZD4, GNAT2, LRP5, PDE6A, PDE6B, PDE6G	0.17
512	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	PFN1	0.13
513	Cone-rod dystrophy 2	Enrichment	PDE6B	0.10
514	Retinitis pigmentosa	Enrichment	PDE6A, PDE6B, PDE6G	0.06
515	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	ROR1	0.06

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Signaling by WNT

Pathway Network for Signaling by WNT

Member Pathways for Signaling by WNT

Pathways in the Signaling by WNT SuperPath

Associated Genes for Signaling by WNT

Associated Disorders for Signaling by WNT

Disorders associated with Signaling by WNT SuperPath

STRING Interaction Network for Signaling by WNT

Sources for Signaling by WNT