Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

No Pathway Network information available for Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Pathways in the Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) SuperPath

#	Name	Source	Genes
1	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)	PubChem	AKT1 AKT1S1 APC ARF6 ARHGEF4 BAD BCAR1 CBL CDC42 CDH1 CRK CRKL CTNNA1 CTNNB1 DEPTOR EGR1 EIF4E EIF4EBP1 EPS15 ETS1 F2RL2 GAB1 GAB2 GRB2 HGF HGS HRAS INPPL1 JUN KPNB1 MAP2K1 MAP2K4 MAP3K1 MAPK3 MAPK8 MET MLST8 MTOR MUC20 NCK1 NUMB PAK1 PAK2 PAK4 PARD6A PDPK1 PIK3CA PIK3R1 PLCG1 PTK2 PTPN1 PTPN11 PTPN2 PTPRJ PXN RAB5A RAC1 RAF1 RANBP10 RANBP9 RAPGEF1 RHOA RIN2 RPTOR SH3GL2 SH3KBP1 SHC1 SNAI1 SOS1 SRC WASL (see all 71) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ARHGEF4	Rho Guanine Nucleotide Exchange Factor 4	Protein Coding	1
2	RIN2	Ras And Rab Interactor 2	Protein Coding	1
3	F2RL2	Coagulation Factor II Thrombin Receptor Like 2	Protein Coding	1
4	DEPTOR	DEP Domain Containing MTOR Interacting Protein	Protein Coding	1
5	PAK4	P21 (RAC1) Activated Kinase 4	Protein Coding	1
6	PTPN2	Protein Tyrosine Phosphatase Non-Receptor Type 2	Protein Coding	1
7	INPPL1	Inositol Polyphosphate Phosphatase Like 1	Protein Coding	1
8	MAP2K4	Mitogen-Activated Protein Kinase Kinase 4	Protein Coding	1
9	ETS1	ETS Proto-Oncogene 1, Transcription Factor	Protein Coding	1
10	EIF4E	Eukaryotic Translation Initiation Factor 4E	Protein Coding	1
11	RPTOR	Regulatory Associated Protein Of MTOR Complex 1	Protein Coding	1
12	EIF4EBP1	Eukaryotic Translation Initiation Factor 4E Binding Protein 1	Protein Coding	1
13	AKT1S1	AKT1 Substrate 1	Protein Coding	1
14	EGR1	Early Growth Response 1	Protein Coding	1
15	PARD6A	Par-6 Family Cell Polarity Regulator Alpha	Protein Coding	1
16	PTPRJ	Protein Tyrosine Phosphatase Receptor Type J	Protein Coding	1
17	MUC20	Mucin 20, Cell Surface Associated	Protein Coding	1
18	RANBP10	RAN Binding Protein 10	Protein Coding	1
19	HGF	Hepatocyte Growth Factor	Protein Coding	1
20	MLST8	MTOR Associated Protein MLST8	Protein Coding	1
21	RAPGEF1	Rap Guanine Nucleotide Exchange Factor 1	Protein Coding	1
22	GAB1	GRB2 Associated Binding Protein 1	Protein Coding	1
23	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	1
24	APC	APC Regulator Of Wnt Signaling Pathway	Protein Coding	1
25	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
26	KPNB1	Karyopherin Subunit Beta 1	Protein Coding	1
27	RAB5A	RAB5A, Member RAS Oncogene Family	Protein Coding	1
28	BCAR1	BCAR1 Scaffold Protein, Cas Family Member	Protein Coding	1
29	PTPN1	Protein Tyrosine Phosphatase Non-Receptor Type 1	Protein Coding	1
30	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	1
31	PXN	Paxillin	Protein Coding	1
32	SNAI1	Snail Family Transcriptional Repressor 1	Protein Coding	1
33	CTNNB1	Catenin Beta 1	Protein Coding	1
34	CTNNA1	Catenin Alpha 1	Protein Coding	1
35	CDH1	Cadherin 1	Protein Coding	1
36	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
37	SH3KBP1	SH3 Domain Containing Kinase Binding Protein 1	Protein Coding	1
38	NUMB	NUMB Endocytic Adaptor Protein	Protein Coding	1
39	RANBP9	RAN Binding Protein 9	Protein Coding	1
40	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
41	WASL	WASP Like Actin Nucleation Promoting Factor	Protein Coding	1
42	NCK1	NCK Adaptor Protein 1	Protein Coding	1
43	PTPN11	Protein Tyrosine Phosphatase Non-Receptor Type 11	Protein Coding	1
44	CDC42	Cell Division Cycle 42	Protein Coding	1
45	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
46	PTK2	Protein Tyrosine Kinase 2	Protein Coding	1
47	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
48	PAK2	P21 (RAC1) Activated Kinase 2	Protein Coding	1
49	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	1
50	RHOA	Ras Homolog Family Member A	Protein Coding	1
51	MET	MET Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	1
52	RAC1	Rac Family Small GTPase 1	Protein Coding	1
53	ARF6	ARF GTPase 6	Protein Coding	1
54	EPS15	Epidermal Growth Factor Receptor Pathway Substrate 15	Protein Coding	1
55	SH3GL2	SH3 Domain Containing GRB2 Like 2, Endophilin A1	Protein Coding	1
56	HGS	Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate	Protein Coding	1
57	CBL	Cbl Proto-Oncogene	Protein Coding	1
58	GAB2	GRB2 Associated Binding Protein 2	Protein Coding	1
59	CRKL	CRK Like Proto-Oncogene, Adaptor Protein	Protein Coding	1
60	BAD	BCL2 Associated Agonist Of Cell Death	Protein Coding	1
61	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	1
62	CRK	CRK Proto-Oncogene, Adaptor Protein	Protein Coding	1
63	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
64	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	1
65	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	1
66	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	1
67	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
68	SHC1	SHC Adaptor Protein 1	Protein Coding	1
69	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
70	MAP3K1	Mitogen-Activated Protein Kinase Kinase Kinase 1	Protein Coding	1
71	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1

Disorders associated with Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Colorectal cancer	Enrichment	AKT1, APC, CDH1, CTNNA1, CTNNB1, MET, PIK3CA, PIK3R1, PTPRJ, SRC	10.43
2	Noonan syndrome and noonan-related syndrome	Enrichment	CBL, HRAS, MAP2K1, PTPN11, RAF1, SOS1	10.02
3	Noonan syndrome 1	Enrichment	CBL, HRAS, MAP2K1, PTPN11, RAF1, SOS1	8.80
4	Rasopathy	Enrichment	CBL, HRAS, MAP2K1, PTPN11, RAF1, SOS1	8.45
5	Noonan syndrome 3	Enrichment	HRAS, PTPN11, RAF1, SOS1	7.62
6	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CBL, CDC42, PTPN11	6.26
7	Ovarian cancer	Enrichment	AKT1, APC, CDH1, CTNNB1, MAP3K1, MET, PIK3CA	6.03
8	Breast cancer	Enrichment	AKT1, APC, CDH1, JUN, PIK3CA, SHC1	5.60
9	Hepatocellular carcinoma	Enrichment	APC, CTNNB1, MET, PIK3CA	5.33
10	Arteriovenous malformation	Enrichment	HRAS, MAP2K1, PIK3CA	4.95
11	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, MAP2K1, PIK3CA	4.79
12	Lung non-small cell carcinoma	Enrichment	HRAS, MAP2K1, PIK3CA	4.66
13	Childhood hepatocellular carcinoma	Enrichment	CTNNB1, MET	4.57
14	Hereditary breast carcinoma	Enrichment	AKT1, APC, CDH1, PIK3CA	4.10
15	Desmoid disease, hereditary	Enrichment	APC, CTNNB1	4.09
16	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	4.09
17	Desmoid tumor	Enrichment	APC, CTNNB1	4.09
18	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CDH1, CTNNA1	3.79
19	Craniopharyngioma	Enrichment	APC, CTNNB1	3.79
20	Noonan syndrome with multiple lentigines	Enrichment	PTPN11, RAF1	3.79
21	Hemimegalencephaly	Enrichment	MTOR, PIK3CA	3.57
22	Hemihyperplasia, isolated	Enrichment	PIK3CA, RHOA	3.40
23	Breast adenocarcinoma	Enrichment	AKT1, PIK3CA	3.40
24	Bladder cancer	Enrichment	CTNNB1, HRAS, PIK3CA	3.34
25	Nevus, epidermal	Enrichment	HRAS, PIK3CA	3.25
26	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1, PIK3CA	3.25
27	Renal cell carcinoma, papillary, 1	Enrichment	MET, MTOR	3.25
28	Gallbladder cancer	Enrichment	CTNNB1, PIK3CA	3.25
29	Overgrowth syndrome	Enrichment	MTOR, PIK3R1	3.25
30	Inherited cancer-predisposing syndrome	Enrichment	APC, CDH1, CTNNA1, MET, PTPN11	3.20
31	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, RAF1	3.13
32	Adult hepatocellular carcinoma	Enrichment	CTNNB1, PIK3CA	3.02
33	Cowden syndrome	Enrichment	AKT1, PIK3CA	3.02
34	Gastric cancer	Enrichment	APC, CDH1, PIK3CA	2.84
35	Juvenile myelomonocytic leukemia	Enrichment	CBL, PTPN11	2.76
36	Meningioma	Enrichment	AKT1, PIK3CA	2.76
37	Lip and oral cavity carcinoma	Enrichment	HRAS, PIK3CA	2.76
38	Medulloblastoma	Enrichment	APC, CTNNB1	2.63
39	46,xy partial gonadal dysgenesis	Enrichment	MAP3K1, SOS1	2.63
40	Renal cell carcinoma, nonpapillary	Enrichment	MET, MTOR	2.57
41	Rhabdomyosarcoma	Enrichment	CBL, HRAS	2.51
42	Macrodactyly	Enrichment	PIK3CA	2.28
43	Proteus syndrome	Enrichment	AKT1	2.28
44	Metachondromatosis	Enrichment	PTPN11	2.28
45	Deafness, autosomal recessive 26	Enrichment	GAB1	2.28
46	Noonan syndrome 5	Enrichment	RAF1	2.28
47	Immunodeficiency 61	Enrichment	SH3KBP1	2.28
48	Noonan syndrome 4	Enrichment	SOS1	2.28
49	Macular dystrophy, patterned, 2	Enrichment	CTNNA1	2.28
50	Deafness, autosomal recessive 39	Enrichment	HGF	2.28
51	Melorheostosis, isolated	Enrichment	MAP2K1	2.28
52	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.28
53	Leopard syndrome 1	Enrichment	PTPN11	2.28
54	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.28
55	Cowden syndrome 5	Enrichment	PIK3CA	2.28
56	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.28
57	46,xy sex reversal 6	Enrichment	MAP3K1	2.28
58	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.28
59	Knobloch syndrome 2	Enrichment	PAK2	2.28
60	Short syndrome	Enrichment	PIK3R1	2.28
61	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	2.28
62	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.28
63	Osteofibrous dysplasia	Enrichment	MET	2.28
64	Autism 19	Enrichment	EIF4E	2.28
65	Deafness, autosomal recessive 97	Enrichment	MET	2.28
66	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.28
67	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.28
68	Melorheostosis	Enrichment	MAP2K1	2.28
69	Autism 9	Enrichment	MET	2.28
70	Leopard syndrome 2	Enrichment	RAF1	2.28
71	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.28
72	Cowden syndrome 6	Enrichment	AKT1	2.28
73	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.28
74	Thrombocytopenia 6	Enrichment	SRC	2.28
75	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	2.28
76	Takenouchi-kosaki syndrome	Enrichment	CDC42	2.28
77	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	2.28
78	Trigonitis	Enrichment	RAF1	2.28
79	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.28
80	Adenoid ameloblastoma	Enrichment	CTNNB1	2.28
81	Arthrogryposis, distal, type 11	Enrichment	MET	2.28
82	Hypospadias	Enrichment	PIK3CA	2.28
83	Thrombocytopenia 10	Enrichment	PTPRJ	2.28
84	Breast lobular carcinoma	Enrichment	CDH1	2.28
85	Rare venous malformation	Enrichment	PIK3CA	2.28
86	Familial adenomatous polyposis	Enrichment	APC	2.28
87	Diaphragmatic eventration	Enrichment	PIK3CA	2.28
88	Nocarh syndrome	Enrichment	CDC42	2.28
89	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.28
90	Rare combined vascular malformation	Enrichment	PIK3CA	2.28
91	Cavernous lymphangioma	Enrichment	PIK3CA	2.28
92	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.28
93	Gardner syndrome	Enrichment	APC	2.28
94	5q22 microdeletion syndrome	Enrichment	APC	2.28
95	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.28
96	Attenuated familial adenomatous polyposis	Enrichment	APC	2.28
97	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.28
98	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.28
99	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.28
100	Macrodactyly of toe	Enrichment	PIK3CA	2.28
101	Microcystic stromal tumor	Enrichment	CTNNB1	2.28
102	Malignant astrocytoma	Enrichment	PTPN11	2.28
103	Endometrial cancer	Enrichment	CDH1, PIK3CA	2.27
104	Hepatoblastoma	Enrichment	APC, CTNNB1	2.27
105	Hydrops fetalis, nonimmune	Enrichment	HRAS, PTPN11	2.09
106	Prostate cancer	Enrichment	CDH1, PIK3CA	2.00
107	Blepharocheilodontic syndrome 1	Enrichment	CDH1	1.98
108	Fibromatosis, gingival, 1	Enrichment	SOS1	1.98
109	Costello syndrome	Enrichment	HRAS	1.98
110	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.98
111	Ovarian germ cell cancer	Enrichment	CBL	1.98
112	Schneckenbecken dysplasia	Enrichment	INPPL1	1.98
113	Pulmonic stenosis	Enrichment	SOS1	1.98
114	Keratosis, seborrheic	Enrichment	PIK3CA	1.98
115	Noonan syndrome 8	Enrichment	PIK3CA	1.98
116	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	1.98
117	Werner syndrome	Enrichment	PTPN11	1.98
118	Cebalid syndrome	Enrichment	MTOR	1.98
119	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	1.98
120	Papillary renal cell carcinoma	Enrichment	MET	1.98
121	Periampullary adenoma	Enrichment	APC	1.98
122	Gastric adenocarcinoma and proximal polyposis of the stomach	Enrichment	APC	1.98
123	Immune system disease	Enrichment	CDC42	1.98
124	Smith-kingsmore syndrome	Enrichment	MTOR	1.98
125	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.98
126	Malignant germ cell tumor of ovary	Enrichment	CBL	1.98
127	Teratoma	Enrichment	CTNNB1	1.98
128	Wooly hair nevus	Enrichment	HRAS	1.98
129	Non-immune hydrops fetalis	Enrichment	HRAS, PTPN11	1.94
130	Lung cancer	Enrichment	MET, PIK3CA	1.92
131	Jacobsen syndrome	Enrichment	ETS1	1.81
132	Opsismodysplasia	Enrichment	INPPL1	1.81
133	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.81
134	Nuchal bleb, familial	Enrichment	SOS1	1.81
135	Langerhans cell histiocytosis	Enrichment	MAP2K1	1.81
136	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.81
137	Cenani-lenz syndactyly syndrome	Enrichment	APC	1.81
138	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	1.81
139	Anus, imperforate	Enrichment	CTNNB1	1.81
140	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.81
141	Large congenital melanocytic nevus	Enrichment	HRAS	1.81
142	Immunodeficiency 14	Enrichment	PIK3R1	1.81
143	Spermatocytoma	Enrichment	HRAS	1.81
144	Butterfly-shaped pigment dystrophy	Enrichment	CTNNA1	1.81
145	Colon adenocarcinoma	Enrichment	APC	1.81
146	Tricuspid valve insufficiency	Enrichment	PTPN11	1.81
147	Renal cell carcinoma	Enrichment	MET	1.81
148	Keratoacanthoma	Enrichment	PIK3CA	1.81
149	Apc-associated polyposis conditions	Enrichment	APC	1.81
150	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS	1.68
151	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K1	1.68
152	Polyposis syndrome, hereditary mixed, 1	Enrichment	CTNNA1	1.68
153	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3CA	1.68
154	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	CRKL	1.68
155	Focal cortical dysplasia, type ii	Enrichment	MTOR	1.68
156	Pilomatrixoma	Enrichment	CTNNB1	1.68
157	Alazami syndrome	Enrichment	CTNNB1	1.68
158	Cardiofaciocutaneous syndrome	Enrichment	MAP2K1	1.68
159	Cerebrovascular disease	Enrichment	PIK3CA	1.68
160	Epidermolytic nevus	Enrichment	HRAS	1.68
161	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.68
162	Knobloch syndrome	Enrichment	PAK2	1.68
163	Isolated focal cortical dysplasia type ii	Enrichment	MTOR	1.68
164	Gingival fibromatosis	Enrichment	SOS1	1.68
165	Capillary malformations, congenital	Enrichment	PIK3CA	1.59
166	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.59
167	Knobloch syndrome 1	Enrichment	PAK2	1.59
168	Familial adenomatous polyposis 1	Enrichment	APC	1.59
169	Lymphoma	Enrichment	PTPN11	1.59
170	Myeloproliferative neoplasm	Enrichment	CBL	1.59
171	Aggressive systemic mastocytosis	Enrichment	CBL	1.59
172	Thrombocytopenia	Enrichment	PTPN11, SRC	1.58
173	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.51
174	Cowden syndrome 1	Enrichment	PIK3CA	1.51
175	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.51
176	Patent ductus arteriosus	Enrichment	PTPN11	1.51
177	Adrenocortical carcinoma	Enrichment	CTNNB1	1.51
178	Lung squamous cell carcinoma	Enrichment	PIK3CA	1.51
179	Cleft lip with or without cleft palate	Enrichment	CDH1	1.51
180	Hereditary breast ovarian cancer syndrome	Enrichment	BCAR1, CTNNA1	1.47
181	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS	1.44
182	Myelofibrosis	Enrichment	SRC	1.44
183	Pilomyxoid astrocytoma	Enrichment	RAF1	1.44
184	Follicular thyroid carcinoma	Enrichment	HRAS	1.44
185	Oligoarticular juvenile idiopathic arthritis	Enrichment	PTPN2	1.44
186	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	PTPN2	1.44
187	Arthrogryposis, distal, type 1a	Enrichment	MET	1.39
188	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.39
189	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	1.34
190	Colonic benign neoplasm	Enrichment	APC	1.34
191	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	1.29
192	Pectus excavatum	Enrichment	PTPN11	1.25
193	46,xy complete gonadal dysgenesis	Enrichment	MAP3K1	1.25
194	Specific learning disability	Enrichment	PTPN11	1.25
195	Epicanthus	Enrichment	PTPN11	1.21
196	Congenital long qt syndrome	Enrichment	PTPN11	1.21
197	Aortic valve disease 1	Enrichment	SOS1	1.18
198	Osteoporosis	Enrichment	SRC	1.15
199	Cleft lip/palate	Enrichment	CDH1	1.15
200	Lynch syndrome	Enrichment	PIK3CA	1.12
201	Rare genetic intellectual disability	Enrichment	MTOR	1.12
202	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	HGF, MET	1.10
203	Polycystic liver disease	Enrichment	CTNNB1	1.07
204	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	1.07
205	Patent foramen ovale	Enrichment	PTPN11	1.04
206	Macs syndrome	Enrichment	RIN2	1.00
207	Craniosynostosis	Enrichment	CTNNA1	1.00
208	Autism spectrum disorder	Enrichment	MAP2K1, PTPN11	0.95
209	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	0.93
210	Scoliosis	Enrichment	PTPN11	0.93
211	Strabismus	Enrichment	PTPN11	0.88
212	Microcephaly	Enrichment	CTNNB1, PTPN11	0.87
213	Differentiated thyroid carcinoma	Enrichment	HRAS	0.85
214	Long qt syndrome 1	Enrichment	PTPN11	0.84
215	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.80
216	Left ventricular noncompaction	Enrichment	RAF1	0.77
217	Systemic lupus erythematosus	Enrichment	ETS1	0.73
218	Type 2 diabetes mellitus	Enrichment	PTPN1	0.70
219	Hypertrophic cardiomyopathy	Enrichment	PTPN11	0.69
220	Sensorineural hearing loss	Enrichment	HGF	0.65
221	Hypertelorism	Enrichment	PIK3CA	0.62
222	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.61
223	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	PTPN11	0.59
224	Dilated cardiomyopathy	Enrichment	RAF1	0.46
225	Congenital nervous system abnormality	Enrichment	CTNNB1	0.37
226	Nervous system disease	Enrichment	CTNNB1	0.37
227	Hereditary retinal dystrophy	Enrichment	CTNNA1	0.10
228	Fundus dystrophy	Enrichment	CTNNA1	0.10

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Pathway Network for Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Member Pathways for Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Pathways in the Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) SuperPath

Associated Genes for Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Associated Disorders for Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Disorders associated with Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) SuperPath

STRING Interaction Network for Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Sources for Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)