Signaling events mediated by VEGFR1 and VEGFR2

No Pathway Network information available for Signaling events mediated by VEGFR1 and VEGFR2

Pathways in the Signaling events mediated by VEGFR1 and VEGFR2 SuperPath

#	Name	Source	Genes
1	Signaling events mediated by VEGFR1 and VEGFR2	PubChem	AKAP1 AKT1 ARF1 BRAF CAMKK2 CAV1 CBL CDC42 CDH5 CTNNA1 CTNNB1 DAG1 DNM2 FBXW11 FES FLT1 FYN GAB1 GRB10 GRB2 HGS HSP90AA1 HSP90AB1 IQGAP1 ITGAV ITGB3 KDR MAP2K1 MAP2K3 MAP2K6 MAPK11 MAPK14 MAPK3 MAPKAPK2 MYOF NCK1 NEDD4 NOS3 PAK2 PDPK1 PIK3CA PIK3R1 PLCG1 PRKACA PRKCA PRKCB PRKCD PTK2 PTK2B PTPN11 PTPN2 PTPN6 PTPRJ PXN RAF1 RHOA ROCK1 SH2D2A SHB SRC VCL VEGFA VTN (see all 63) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	MYOF	Myoferlin	Protein Coding	1
2	MAP2K3	Mitogen-Activated Protein Kinase Kinase 3	Protein Coding	1
3	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	1
4	PTPN2	Protein Tyrosine Phosphatase Non-Receptor Type 2	Protein Coding	1
5	FBXW11	F-Box And WD Repeat Domain Containing 11	Protein Coding	1
6	CAMKK2	Calcium/Calmodulin Dependent Protein Kinase Kinase 2	Protein Coding	1
7	PTPRJ	Protein Tyrosine Phosphatase Receptor Type J	Protein Coding	1
8	NEDD4	NEDD4 E3 Ubiquitin Protein Ligase	Protein Coding	1
9	CDH5	Cadherin 5	Protein Coding	1
10	SH2D2A	SH2 Domain Containing 2A	Protein Coding	1
11	SHB	SH2 Domain Containing Adaptor Protein B	Protein Coding	1
12	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	1
13	GRB10	Growth Factor Receptor Bound Protein 10	Protein Coding	1
14	GAB1	GRB2 Associated Binding Protein 1	Protein Coding	1
15	PRKCD	Protein Kinase C Delta	Protein Coding	1
16	ROCK1	Rho Associated Coiled-Coil Containing Protein Kinase 1	Protein Coding	1
17	HSP90AB1	Heat Shock Protein 90 Alpha Family Class B Member 1	Protein Coding	1
18	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
19	NOS3	Nitric Oxide Synthase 3	Protein Coding	1
20	MAPKAPK2	MAPK Activated Protein Kinase 2	Protein Coding	1
21	CAV1	Caveolin 1	Protein Coding	1
22	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	1
23	PTPN6	Protein Tyrosine Phosphatase Non-Receptor Type 6	Protein Coding	1
24	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
25	VTN	Vitronectin	Protein Coding	1
26	IQGAP1	IQ Motif Containing GTPase Activating Protein 1	Protein Coding	1
27	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	1
28	PXN	Paxillin	Protein Coding	1
29	CTNNB1	Catenin Beta 1	Protein Coding	1
30	CTNNA1	Catenin Alpha 1	Protein Coding	1
31	VCL	Vinculin	Protein Coding	1
32	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	1
33	ITGAV	Integrin Subunit Alpha V	Protein Coding	1
34	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
35	DAG1	Dystroglycan 1	Protein Coding	1
36	PRKCA	Protein Kinase C Alpha	Protein Coding	1
37	NCK1	NCK Adaptor Protein 1	Protein Coding	1
38	PTPN11	Protein Tyrosine Phosphatase Non-Receptor Type 11	Protein Coding	1
39	CDC42	Cell Division Cycle 42	Protein Coding	1
40	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
41	PTK2	Protein Tyrosine Kinase 2	Protein Coding	1
42	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
43	PAK2	P21 (RAC1) Activated Kinase 2	Protein Coding	1
44	FES	FES Proto-Oncogene, Tyrosine Kinase	Protein Coding	1
45	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
46	RHOA	Ras Homolog Family Member A	Protein Coding	1
47	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
48	HSP90AA1	Heat Shock Protein 90 Alpha Family Class A Member 1	Protein Coding	1
49	HGS	Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate	Protein Coding	1
50	DNM2	Dynamin 2	Protein Coding	1
51	ARF1	ARF GTPase 1	Protein Coding	1
52	CBL	Cbl Proto-Oncogene	Protein Coding	1
53	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	1
54	PRKCB	Protein Kinase C Beta	Protein Coding	1
55	ITGB3	Integrin Subunit Beta 3	Protein Coding	1
56	KDR	Kinase Insert Domain Receptor	Protein Coding	1
57	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
58	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
59	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
60	AKAP1	A-Kinase Anchoring Protein 1	Protein Coding	1
61	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
62	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
63	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1

Disorders associated with Signaling events mediated by VEGFR1 and VEGFR2 SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF, CBL, MAP2K1, PTPN11, RAF1	8.27
2	Colorectal cancer	Enrichment	AKT1, BRAF, CTNNA1, CTNNB1, PIK3CA, PIK3R1, PTPRJ, SRC	8.22
3	Noonan syndrome 1	Enrichment	BRAF, CBL, MAP2K1, PTPN11, RAF1	7.24
4	Rasopathy	Enrichment	BRAF, CBL, MAP2K1, PTPN11, RAF1	6.95
5	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CBL, CDC42, PTPN11	6.42
6	Noonan syndrome with multiple lentigines	Enrichment	BRAF, PTPN11, RAF1	6.42
7	Gallbladder cancer	Enrichment	BRAF, CTNNB1, PIK3CA	5.48
8	Lung non-small cell carcinoma	Enrichment	BRAF, MAP2K1, PIK3CA	4.81
9	Langerhans cell histiocytosis	Enrichment	BRAF, MAP2K1	4.20
10	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	4.20
11	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF, MAP2K1	3.90
12	Cardiofaciocutaneous syndrome	Enrichment	BRAF, MAP2K1	3.90
13	Craniopharyngioma	Enrichment	BRAF, CTNNB1	3.90
14	Pre-eclampsia	Enrichment	FLT1, NOS3	3.68
15	Hemihyperplasia, isolated	Enrichment	PIK3CA, RHOA	3.50
16	Breast adenocarcinoma	Enrichment	AKT1, PIK3CA	3.50
17	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1, PIK3CA	3.36
18	Noonan syndrome 3	Enrichment	PTPN11, RAF1	3.36
19	Pilomyxoid astrocytoma	Enrichment	BRAF, RAF1	3.36
20	Melanocytic nevus syndrome, congenital	Enrichment	BRAF, RAF1	3.23
21	Arteriovenous malformation	Enrichment	MAP2K1, PIK3CA	3.13
22	Adult hepatocellular carcinoma	Enrichment	CTNNB1, PIK3CA	3.13
23	Cowden syndrome	Enrichment	AKT1, PIK3CA	3.13
24	Myopathy, x-linked, with excessive autophagy	Enrichment	MAP2K1, PIK3CA	3.03
25	Juvenile myelomonocytic leukemia	Enrichment	CBL, PTPN11	2.87
26	Meningioma	Enrichment	AKT1, PIK3CA	2.87
27	Lip and oral cavity carcinoma	Enrichment	BRAF, PIK3CA	2.87
28	Thrombocytopenia	Enrichment	ITGB3, PTPN11, SRC	2.85
29	Hepatocellular carcinoma	Enrichment	CTNNB1, PIK3CA	2.34
30	Macrodactyly	Enrichment	PIK3CA	2.33
31	Proteus syndrome	Enrichment	AKT1	2.33
32	Metachondromatosis	Enrichment	PTPN11	2.33
33	Deafness, autosomal recessive 26	Enrichment	GAB1	2.33
34	Noonan syndrome 5	Enrichment	RAF1	2.33
35	Lipodystrophy, congenital generalized, type 3	Enrichment	CAV1	2.33
36	Macular dystrophy, patterned, 2	Enrichment	CTNNA1	2.33
37	Melorheostosis, isolated	Enrichment	MAP2K1	2.33
38	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.33
39	Noonan syndrome 7	Enrichment	BRAF	2.33
40	Leopard syndrome 3	Enrichment	BRAF	2.33
41	Leopard syndrome 1	Enrichment	PTPN11	2.33
42	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.33
43	Cowden syndrome 5	Enrichment	PIK3CA	2.33
44	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.33
45	Muscular dystrophy-dystroglycanopathy , type a, 9	Enrichment	DAG1	2.33
46	Charcot-marie-tooth disease, dominant intermediate b	Enrichment	DNM2	2.33
47	Pulmonary hypertension, primary, 3	Enrichment	CAV1	2.33
48	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	2.33
49	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.33
50	Knobloch syndrome 2	Enrichment	PAK2	2.33
51	Short syndrome	Enrichment	PIK3R1	2.33
52	Neurodevelopmental, jaw, eye, and digital syndrome	Enrichment	FBXW11	2.33
53	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.33
54	Angioedema, hereditary, 7	Enrichment	MYOF	2.33
55	Lipodystrophy, familial partial, type 7	Enrichment	CAV1	2.33
56	Microvascular complications of diabetes 1	Enrichment	VEGFA	2.33
57	Cardiomyopathy, dilated, 1w	Enrichment	VCL	2.33
58	Lymphangioma	Enrichment	BRAF	2.33
59	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.33
60	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.33
61	Phace association	Enrichment	BRAF	2.33
62	Melorheostosis	Enrichment	MAP2K1	2.33
63	Leopard syndrome 2	Enrichment	RAF1	2.33
64	Lethal congenital contracture syndrome 5	Enrichment	DNM2	2.33
65	Cardiomyopathy, familial hypertrophic, 15	Enrichment	VCL	2.33
66	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.33
67	Cowden syndrome 6	Enrichment	AKT1	2.33
68	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	2.33
69	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.33
70	Muscular dystrophy-dystroglycanopathy , type c, 9	Enrichment	DAG1	2.33
71	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	2.33
72	Thrombocytopenia 6	Enrichment	SRC	2.33
73	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	2.33
74	Takenouchi-kosaki syndrome	Enrichment	CDC42	2.33
75	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	2.33
76	Trigonitis	Enrichment	RAF1	2.33
77	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.33
78	Tufted angioma of skin	Enrichment	KDR	2.33
79	Adenoid ameloblastoma	Enrichment	CTNNB1	2.33
80	Autosomal dominant charcot-marie-tooth disease type 2m	Enrichment	DNM2	2.33
81	Hypospadias	Enrichment	PIK3CA	2.33
82	Thrombocytopenia 10	Enrichment	PTPRJ	2.33
83	Rare venous malformation	Enrichment	PIK3CA	2.33
84	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	2.33
85	Vegetative pyoderma gangrenosum	Enrichment	PTPN6	2.33
86	Bullous pyoderma gangrenosum	Enrichment	PTPN6	2.33
87	Diaphragmatic eventration	Enrichment	PIK3CA	2.33
88	Pustular pyoderma gangrenosum	Enrichment	PTPN6	2.33
89	Nocarh syndrome	Enrichment	CDC42	2.33
90	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.33
91	Syringocystadenoma papilliferum	Enrichment	BRAF	2.33
92	Rare combined vascular malformation	Enrichment	PIK3CA	2.33
93	Ganglioglioma	Enrichment	BRAF	2.33
94	Cavernous lymphangioma	Enrichment	PIK3CA	2.33
95	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.33
96	Nongerminomatous germ cell tumor	Enrichment	BRAF	2.33
97	Phace syndrome	Enrichment	BRAF	2.33
98	Muscle-eye-brain disease with bilateral multicystic leucodystrophy	Enrichment	DAG1	2.33
99	Classic hairy cell leukemia	Enrichment	BRAF	2.33
100	Classic pyoderma gangrenosum	Enrichment	PTPN6	2.33
101	Silver-russell syndrome due to maternal uniparental disomy of chromosome 7	Enrichment	GRB10	2.33
102	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.33
103	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.33
104	Macrodactyly of toe	Enrichment	PIK3CA	2.33
105	Microcystic stromal tumor	Enrichment	CTNNB1	2.33
106	Malignant astrocytoma	Enrichment	PTPN11	2.33
107	Dilated cardiomyopathy	Enrichment	BRAF, RAF1, VCL	2.22
108	Bladder cancer	Enrichment	CTNNB1, PIK3CA	2.10
109	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	2.03
110	Ovarian germ cell cancer	Enrichment	CBL	2.03
111	Pulmonic stenosis	Enrichment	BRAF	2.03
112	Keratosis, seborrheic	Enrichment	PIK3CA	2.03
113	Angioma, tufted	Enrichment	KDR	2.03
114	Noonan syndrome 8	Enrichment	PIK3CA	2.03
115	Periventricular nodular heterotopia 8	Enrichment	ARF1	2.03
116	Werner syndrome	Enrichment	PTPN11	2.03
117	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	2.03
118	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	2.03
119	Fibrolamellar carcinoma	Enrichment	PRKACA	2.03
120	Immune system disease	Enrichment	CDC42	2.03
121	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	2.03
122	Malignant germ cell tumor of ovary	Enrichment	CBL	2.03
123	Teratoma	Enrichment	CTNNB1	2.03
124	Lung cancer	Enrichment	BRAF, PIK3CA	2.02
125	Ovarian cancer	Enrichment	AKT1, CTNNB1, PIK3CA	1.94
126	Desmoid disease, hereditary	Enrichment	CTNNB1	1.86
127	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3	1.86
128	Ataxia-telangiectasia	Enrichment	BRAF	1.86
129	Bleeding disorder, platelet-type, 16	Enrichment	ITGB3	1.86
130	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.86
131	Myopathy, centronuclear, x-linked	Enrichment	DNM2	1.86
132	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.86
133	Neutrophilic dermatosis, acute febrile	Enrichment	PTPN6	1.86
134	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	1.86
135	Anus, imperforate	Enrichment	CTNNB1	1.86
136	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.86
137	Tethered spinal cord syndrome	Enrichment	BRAF	1.86
138	Desmoid tumor	Enrichment	CTNNB1	1.86
139	Immunodeficiency 14	Enrichment	PIK3R1	1.86
140	Butterfly-shaped pigment dystrophy	Enrichment	CTNNA1	1.86
141	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	1.86
142	Tricuspid valve insufficiency	Enrichment	PTPN11	1.86
143	Keratoacanthoma	Enrichment	PIK3CA	1.86
144	Hereditary breast carcinoma	Enrichment	AKT1, PIK3CA	1.75
145	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CTNNA1	1.73
146	Thyroid cancer, nonmedullary, 1	Enrichment	BRAF	1.73
147	Polyposis syndrome, hereditary mixed, 1	Enrichment	CTNNA1	1.73
148	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3CA	1.73
149	Pilomatrixoma	Enrichment	CTNNB1	1.73
150	Alazami syndrome	Enrichment	CTNNB1	1.73
151	Cerebrovascular disease	Enrichment	PIK3CA	1.73
152	Newborn respiratory distress syndrome	Enrichment	BRAF	1.73
153	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.73
154	Knobloch syndrome	Enrichment	PAK2	1.73
155	Hereditary angioedema with normal c1inh not related to f12 or plg variant	Enrichment	MYOF	1.73
156	Capillary malformations, congenital	Enrichment	PIK3CA	1.64
157	Alzheimer disease 2	Enrichment	NOS3	1.64
158	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.64
159	Knobloch syndrome 1	Enrichment	PAK2	1.64
160	Glanzmann thrombasthenia 2	Enrichment	ITGB3	1.64
161	Lymphoma	Enrichment	PTPN11	1.64
162	Myeloproliferative neoplasm	Enrichment	CBL	1.64
163	Hemimegalencephaly	Enrichment	PIK3CA	1.64
164	Aggressive systemic mastocytosis	Enrichment	CBL	1.64
165	Diffuse cutaneous systemic sclerosis	Enrichment	CAV1	1.64
166	Familial isolated dilated cardiomyopathy	Enrichment	RAF1, VCL	1.60
167	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.56
168	Myopathy, centronuclear, 1	Enrichment	DNM2	1.56
169	Cowden syndrome 1	Enrichment	PIK3CA	1.56
170	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.56
171	Wilms tumor 5	Enrichment	BRAF	1.56
172	Hemangioma, capillary infantile	Enrichment	KDR	1.56
173	Patent ductus arteriosus	Enrichment	PTPN11	1.56
174	Adrenocortical carcinoma	Enrichment	CTNNB1	1.56
175	Limited scleroderma	Enrichment	CAV1	1.56
176	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGB3	1.56
177	Lung squamous cell carcinoma	Enrichment	PIK3CA	1.56
178	Primary ovarian insufficiency	Enrichment	KDR, NOS3	1.51
179	Nevus, epidermal	Enrichment	PIK3CA	1.49
180	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF	1.49
181	Myelofibrosis	Enrichment	SRC	1.49
182	Glanzmann thrombasthenia 1	Enrichment	ITGB3	1.49
183	Follicular thyroid carcinoma	Enrichment	BRAF	1.49
184	Oligoarticular juvenile idiopathic arthritis	Enrichment	PTPN2	1.49
185	Overgrowth syndrome	Enrichment	PIK3R1	1.49
186	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	PTPN2	1.49
187	Lymphoma, non-hodgkin, familial	Enrichment	BRAF	1.44
188	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.44
189	Cardiomyopathy, familial hypertrophic, 4	Enrichment	BRAF	1.39
190	Ellis-van creveld syndrome	Enrichment	PRKACA	1.39
191	Primary hyperaldosteronism	Enrichment	BRAF	1.39
192	Ventricular septal defect	Enrichment	BRAF	1.39
193	Stroke, ischemic	Enrichment	NOS3	1.34
194	Melanoma	Enrichment	BRAF	1.34
195	Autosomal dominant macrothrombocytopenia	Enrichment	ITGB3	1.34
196	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	1.34
197	Breast cancer	Enrichment	AKT1, PIK3CA	1.32
198	Pectus excavatum	Enrichment	PTPN11	1.30
199	Heritable pulmonary arterial hypertension	Enrichment	CAV1	1.30
200	Specific learning disability	Enrichment	PTPN11	1.30
201	Epicanthus	Enrichment	PTPN11	1.26
202	Congenital long qt syndrome	Enrichment	PTPN11	1.26
203	Osteoporosis	Enrichment	SRC	1.20
204	Medulloblastoma	Enrichment	CTNNB1	1.20
205	Lung cancer susceptibility 3	Enrichment	BRAF	1.20
206	Periventricular nodular heterotopia	Enrichment	ARF1	1.20
207	Walker-warburg syndrome	Enrichment	DAG1	1.20
208	Wilms tumor 1	Enrichment	BRAF	1.17
209	Lynch syndrome	Enrichment	PIK3CA	1.17
210	Creatine phosphokinase, elevated serum	Enrichment	DAG1	1.14
211	Isolated elevated serum creatine phosphokinase levels	Enrichment	DAG1	1.14
212	Rhabdomyosarcoma	Enrichment	CBL	1.14
213	Alzheimer disease, familial, 1	Enrichment	NOS3	1.12
214	Hypertension, essential	Enrichment	NOS3	1.12
215	Melanoma, cutaneous malignant 1	Enrichment	BRAF	1.12
216	Dandy-walker syndrome	Enrichment	BRAF	1.12
217	Polycystic liver disease	Enrichment	CTNNB1	1.12
218	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	1.12
219	Patent foramen ovale	Enrichment	PTPN11	1.09
220	Arteriovenous malformations of the brain	Enrichment	BRAF	1.07
221	Diffuse large b-cell lymphoma	Enrichment	BRAF	1.07
222	Craniosynostosis	Enrichment	CTNNA1	1.05
223	Autism spectrum disorder	Enrichment	MAP2K1, PTPN11	1.04
224	Endometrial cancer	Enrichment	PIK3CA	1.03
225	Centronuclear myopathy	Enrichment	DNM2	1.03
226	Hepatoblastoma	Enrichment	CTNNB1	1.03
227	Myocardial infarction	Enrichment	ITGB3	1.01
228	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	0.98
229	Scoliosis	Enrichment	PTPN11	0.98
230	Microcephaly	Enrichment	CTNNB1, PTPN11	0.95
231	Tetralogy of fallot	Enrichment	KDR	0.94
232	Hydrops fetalis, nonimmune	Enrichment	PTPN11	0.94
233	Strabismus	Enrichment	PTPN11	0.93
234	Inherited cancer-predisposing syndrome	Enrichment	CTNNA1, PTPN11	0.90
235	Prostate cancer	Enrichment	PIK3CA	0.90
236	Severe covid-19	Enrichment	ITGAV	0.90
237	Differentiated thyroid carcinoma	Enrichment	BRAF	0.90
238	Long qt syndrome 1	Enrichment	PTPN11	0.88
239	Non-immune hydrops fetalis	Enrichment	PTPN11	0.87
240	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.85
241	Left ventricular noncompaction	Enrichment	RAF1	0.82
242	Myopathy	Enrichment	DNM2	0.77
243	Charcot-marie-tooth disease	Enrichment	DNM2	0.76
244	Gastric cancer	Enrichment	PIK3CA	0.74
245	Hypertrophic cardiomyopathy	Enrichment	PTPN11	0.74
246	Hypertelorism	Enrichment	PIK3CA	0.67
247	Hereditary breast ovarian cancer syndrome	Enrichment	CTNNA1	0.65
248	Myeloma, multiple	Enrichment	BRAF	0.64
249	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	PTPN11	0.64
250	Congenital nervous system abnormality	Enrichment	CTNNB1	0.41
251	Nervous system disease	Enrichment	CTNNB1	0.41
252	Complex neurodevelopmental disorder	Enrichment	FBXW11	0.36
253	Hereditary retinal dystrophy	Enrichment	CTNNA1	0.13
254	Fundus dystrophy	Enrichment	CTNNA1	0.13

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Signaling events mediated by VEGFR1 and VEGFR2

Pathway Network for Signaling events mediated by VEGFR1 and VEGFR2

Member Pathways for Signaling events mediated by VEGFR1 and VEGFR2

Pathways in the Signaling events mediated by VEGFR1 and VEGFR2 SuperPath

Associated Genes for Signaling events mediated by VEGFR1 and VEGFR2

Associated Disorders for Signaling events mediated by VEGFR1 and VEGFR2

Disorders associated with Signaling events mediated by VEGFR1 and VEGFR2 SuperPath

STRING Interaction Network for Signaling events mediated by VEGFR1 and VEGFR2

Sources for Signaling events mediated by VEGFR1 and VEGFR2