SLIT2:ROBO1 increases RHOA activity

No Pathway Network information available for SLIT2:ROBO1 increases RHOA activity

#	Name	Source	Genes
1	SLIT2:ROBO1 increases RHOA activity	Reactome	MYO9B RHOA ROBO1 SLIT2

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RHOA	Ras Homolog Family Member A	Protein Coding	1
2	MYO9B	Myosin IXB	Protein Coding	1
3	ROBO1	Roundabout Guidance Receptor 1	Protein Coding	1
4	SLIT2	Slit Guidance Ligand 2	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Cakut	Enrichment	ROBO1, SLIT2	4.44
2	Nystagmus 8, congenital, autosomal recessive	Enrichment	ROBO1	3.53
3	Celiac disease 4	Enrichment	MYO9B	3.53
4	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	3.53
5	Autosomal recessive congenital nystagmus	Enrichment	ROBO1	3.53
6	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	3.53
7	Pituitary hormone deficiency, combined or isolated, 8	Enrichment	ROBO1	3.53
8	Neurooculorenal syndrome	Enrichment	ROBO1	3.53
9	Congenital nystagmus	Enrichment	ROBO1	3.53
10	Hemihyperplasia, isolated	Enrichment	RHOA	2.75
11	Renal agenesis, bilateral	Enrichment	ROBO1	2.58
12	Pituitary stalk interruption syndrome	Enrichment	ROBO1	2.38
13	Tetralogy of fallot	Enrichment	ROBO1	2.12

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for SLIT2:ROBO1 increases RHOA activity