Sulfation biotransformation reaction
Pathways in the Sulfation biotransformation reaction SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Sulfation biotransformation reaction | WikiPathways |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | PAPSS1 | 3''-Phosphoadenosine 5''-Phosphosulfate Synthase 1 | Protein Coding | 1 |
| 2 | PAPSS2 | 3''-Phosphoadenosine 5''-Phosphosulfate Synthase 2 | Protein Coding | 1 |
| 3 | SULT2A1 | Sulfotransferase Family 2A Member 1 | Protein Coding | 1 |
| 4 | SULT2B1 | Sulfotransferase Family 2B Member 1 | Protein Coding | 1 |
| 5 | SULT1C2 | Sulfotransferase Family 1C Member 2 | Protein Coding | 1 |
| 6 | SULT1A1 | Sulfotransferase Family 1A Member 1 | Protein Coding | 1 |
| 7 | SULT1A2 | Sulfotransferase Family 1A Member 2 | Protein Coding | 1 |
| 8 | SULT1E1 | Sulfotransferase Family 1E Member 1 | Protein Coding | 1 |
| 9 | SULT1C3 | Sulfotransferase Family 1C Member 3 | Protein Coding | 1 |
| 10 | GSR | Glutathione-Disulfide Reductase | Protein Coding | 1 |
| 11 | SULT1B1 | Sulfotransferase Family 1B Member 1 | Protein Coding | 1 |
| 12 | G6PD | Glucose-6-Phosphate Dehydrogenase | Protein Coding | 1 |
| 13 | SULT1A4 | Sulfotransferase Family 1A Member 4 | Protein Coding | 1 |
| 14 | SULT6B1 | Sulfotransferase Family 6B Member 1 | Protein Coding | 1 |
| 15 | SLX1A-SULT1A3 | SLX1A-SULT1A3 Readthrough (NMD Candidate) | RNA Gene | 1 |
| 16 | SULT1C4 | Sulfotransferase Family 1C Member 4 | Protein Coding | 1 |
| 17 | SULT4A1 | Sulfotransferase Family 4A Member 1 | Protein Coding | 1 |
Disorders associated with Sulfation biotransformation reaction SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Brachyolmia type 4 with mild epiphyseal and metaphyseal changes | Enrichment | PAPSS2 | 2.90 |
| 2 | Anemia, congenital, nonspherocytic hemolytic, 10 | Enrichment | GSR | 2.90 |
| 3 | Ichthyosis, congenital, autosomal recessive 14 | Enrichment | SULT2B1 | 2.90 |
| 4 | Brachyolmia | Enrichment | PAPSS2 | 2.90 |
| 5 | Autosomal recessive brachyolmia | Enrichment | PAPSS2 | 2.90 |
| 6 | Congenital nonspherocytic hemolytic anemia | Enrichment | G6PD | 2.90 |
| 7 | Congenital hemolytic anemia | Enrichment | G6PD | 2.60 |
| 8 | Glucosephosphate dehydrogenase deficiency | Enrichment | G6PD | 2.60 |
| 9 | Ichthyosis, congenital, autosomal recessive 1 | Enrichment | SULT2B1 | 2.43 |
| 10 | Ichthyosis, congenital, autosomal recessive 2 | Enrichment | SULT2B1 | 2.20 |
| 11 | Anemia, congenital, nonspherocytic hemolytic, 1 | Enrichment | G6PD | 2.20 |
| 12 | Coronary heart disease 5 | Enrichment | G6PD | 1.95 |
| 13 | Congenital nonbullous ichthyosiform erythroderma | Enrichment | SULT2B1 | 1.90 |
| 14 | Autosomal recessive congenital ichthyosis | Enrichment | SULT2B1 | 1.73 |
| 15 | Malaria | Enrichment | G6PD | 1.55 |