Sumoylation by RanBP2 regulates transcriptional repression

No Pathway Network information available for Sumoylation by RanBP2 regulates transcriptional repression

Pathways in the Sumoylation by RanBP2 regulates transcriptional repression SuperPath

#	Name	Source	Genes
1	Sumoylation by RanBP2 regulates transcriptional repression	PubChem	HDAC1 HDAC4 MDM2 NUP153 NUP210 NUP214 NUP62 PIAS1 PIAS2 RAN RANBP2 RANGAP1 SUMO1 UBE2I XPO1 (see all 15) (see less)
2	SUMOylation of nuclear envelope proteins	Reactome	RANGAP1 SUMO1 UBE2I

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RANGAP1	Ran GTPase Activating Protein 1	Protein Coding	2
2	SUMO1	Small Ubiquitin Like Modifier 1	Protein Coding	2
3	UBE2I	Ubiquitin Conjugating Enzyme E2 I	Protein Coding	2
4	HDAC4	Histone Deacetylase 4	Protein Coding	1
5	XPO1	Exportin 1	Protein Coding	1
6	RAN	RAN, Member RAS Oncogene Family	Protein Coding	1
7	PIAS2	Protein Inhibitor Of Activated STAT 2	Protein Coding	1
8	NUP210	Nucleoporin 210	Protein Coding	1
9	NUP153	Nucleoporin 153	Protein Coding	1
10	NUP214	Nucleoporin 214	Protein Coding	1
11	NUP62	Nucleoporin 62	Protein Coding	1
12	RANBP2	RAN Binding Protein 2	Protein Coding	1
13	MDM2	MDM2 Proto-Oncogene	Protein Coding	1
14	PIAS1	Protein Inhibitor Of Activated STAT 1	Protein Coding	1
15	HDAC1	Histone Deacetylase 1	Protein Coding	1

Disorders associated with Sumoylation by RanBP2 regulates transcriptional repression SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Orofacial cleft 10	Enrichment	SUMO1	3.66
2	Tooth agenesis	Enrichment	RANBP2, SUMO1	3.58
3	Nephronophthisis-like nephropathy 1	Enrichment	RANGAP1	3.35
4	Accelerated tumor formation	Enrichment	MDM2	2.96
5	Chromosome 2q37 deletion syndrome	Enrichment	HDAC4	2.96
6	Lessel-kubisch syndrome	Enrichment	MDM2	2.96
7	Encephalopathy, acute, infection-induced 9	Enrichment	NUP214	2.96
8	Neurodevelopmental disorder with central hypotonia and dysmorphic facies	Enrichment	HDAC4	2.96
9	Familial acute necrotizing encephalopathy	Enrichment	RANBP2	2.96
10	Striatonigral degeneration, infantile	Enrichment	NUP62	2.66
11	Acute myeloid leukemia with t(6;9) (p23;q34.1)	Enrichment	NUP214	2.66
12	Primary mediastinal large b-cell lymphoma	Enrichment	XPO1	2.66
13	Acute necrotizing encephalopathy of childhood	Enrichment	RANBP2	2.66
14	Ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	RANBP2	2.48
15	Dedifferentiated liposarcoma	Enrichment	MDM2	2.48
16	Well-differentiated liposarcoma	Enrichment	MDM2	2.48
17	Ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive	Enrichment	RANBP2	2.35
18	Ectodermal dysplasia	Enrichment	RANBP2	2.35
19	Familial infantile bilateral striatal necrosis	Enrichment	NUP62	2.35
20	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	RANBP2	2.26
21	Autosomal recessive hypohidrotic ectodermal dysplasia syndrome	Enrichment	RANBP2	2.26
22	Li-fraumeni syndrome	Enrichment	MDM2	2.18
23	Inflammatory myofibroblastic tumor	Enrichment	RANBP2	2.18
24	Mitochondrial dna depletion syndrome 4a	Enrichment	RANBP2	2.11
25	Mitochondrial dna depletion syndrome 4b	Enrichment	RANBP2	2.05
26	Precursor t-cell acute lymphoblastic leukemia	Enrichment	NUP214	1.60
27	Nephronophthisis	Enrichment	PIAS1	1.44
28	Leukemia, acute myeloid	Enrichment	NUP214	1.36
29	Myeloma, multiple	Enrichment	HDAC4	1.22

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Sumoylation by RanBP2 regulates transcriptional repression

Pathway Network for Sumoylation by RanBP2 regulates transcriptional repression

Member Pathways for Sumoylation by RanBP2 regulates transcriptional repression

Pathways in the Sumoylation by RanBP2 regulates transcriptional repression SuperPath

Associated Genes for Sumoylation by RanBP2 regulates transcriptional repression

Associated Disorders for Sumoylation by RanBP2 regulates transcriptional repression

Disorders associated with Sumoylation by RanBP2 regulates transcriptional repression SuperPath

STRING Interaction Network for Sumoylation by RanBP2 regulates transcriptional repression

Sources for Sumoylation by RanBP2 regulates transcriptional repression