superpathway of glycosphingolipids biosynthesis

Pathway network for the superpathway of glycosphingolipids biosynthesis SuperPath

Sources:

PubChem

Pathways in the superpathway of glycosphingolipids biosynthesis SuperPath

#	Name	Source	Genes
1	superpathway of glycosphingolipids biosynthesis	PubChem	A4GALT B3GALNT1 B3GALT1 B3GALT4 B3GALT5 B3GNT2 B3GNT5 B4GALNT1 B4GALT1 B4GALT2 B4GALT3 B4GALT4 B4GALT6 FUT1 FUT2 GBGT1 ST3GAL2 ST3GAL3 ST3GAL5 ST3GAL6 ST6GAL1 ST8SIA1 UGCG (see all 23) (see less)
2	super pathway of glycosphingolipids biosynthesis	PubChem	A4GALT B3GALNT1 B3GALT1 B3GALT4 B3GALT5 B3GNT2 B3GNT5 B4GALNT1 B4GALT1 B4GALT2 B4GALT3 B4GALT4 B4GALT6 FUT1 FUT2 GBGT1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL5 ST3GAL6 ST6GAL1 ST8SIA1 ST8SIA2 ST8SIA3 UGCG (see all 26) (see less)
3	neolacto-series glycosphingolipids biosynthesis	PubChem	B3GNT2 B3GNT5 B4GALT1 B4GALT2 B4GALT3 B4GALT4 B4GALT6 ST3GAL6 ST6GAL1 UGCG (see all 10) (see less)
4	globo-series glycosphingolipids biosynthesis	PubChem	A4GALT B3GALNT1 B3GALT5 B4GALT6 FUT1 FUT2 GBGT1 ST3GAL2 UGCG (see all 9) (see less)
5	ganglio-series glycosphingolipids biosynthesis	PubChem	B3GALT4 B4GALNT1 B4GALT6 ST3GAL2 ST3GAL3 ST3GAL5 ST6GAL1 ST8SIA1 UGCG (see all 9) (see less)
6	lacto-series glycosphingolipids biosynthesis	PubChem	B3GALT1 B3GALT5 B3GNT5 B4GALT6 FUT2 ST3GAL5 ST6GAL1 UGCG (see all 8) (see less)

Gene overlap in member pathways for superpathway of glycosphingolipids biosynthesis SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	UGCG	UDP-Glucose Ceramide Glucosyltransferase	Protein Coding	6
2	B4GALT6	Beta-1,4-Galactosyltransferase 6	Protein Coding	6
3	ST6GAL1	ST6 Beta-Galactoside Alpha-2,6-Sialyltransferase 1	Protein Coding	5
4	B3GALT5	Beta-1,3-Galactosyltransferase 5	Protein Coding	4
5	ST3GAL2	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 2	Protein Coding	4
6	B3GNT5	UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 5	Protein Coding	4
7	ST3GAL5	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 5	Protein Coding	4
8	FUT2	Fucosyltransferase 2 (H Blood Group)	Protein Coding	4
9	ST8SIA1	ST8 Alpha-N-Acetyl-Neuraminide Alpha-2,8-Sialyltransferase 1	Protein Coding	3
10	GBGT1	Globoside Alpha-1,3-N-Acetylgalactosaminyltransferase 1 (FORS Blood Group)	Protein Coding	3
11	ST3GAL6	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 6	Protein Coding	3
12	B3GNT2	UDP-GlcNAc:BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 2	Protein Coding	3
13	B3GALT1	Beta-1,3-Galactosyltransferase 1	Protein Coding	3
14	A4GALT	Alpha 1,4-Galactosyltransferase (P1PK Blood Group)	Protein Coding	3
15	B3GALT4	Beta-1,3-Galactosyltransferase 4	Protein Coding	3
16	B3GALNT1	Beta-1,3-N-Acetylgalactosaminyltransferase 1 (Globoside Blood Group)	Protein Coding	3
17	B4GALNT1	Beta-1,4-N-Acetyl-Galactosaminyltransferase 1	Protein Coding	3
18	ST3GAL3	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 3	Protein Coding	3
19	FUT1	Fucosyltransferase 1 (H Blood Group)	Protein Coding	3
20	B4GALT2	Beta-1,4-Galactosyltransferase 2	Protein Coding	3
21	B4GALT4	Beta-1,4-Galactosyltransferase 4	Protein Coding	3
22	B4GALT3	Beta-1,4-Galactosyltransferase 3	Protein Coding	3
23	B4GALT1	Beta-1,4-Galactosyltransferase 1	Protein Coding	3
24	ST8SIA3	ST8 Alpha-N-Acetyl-Neuraminide Alpha-2,8-Sialyltransferase 3	Protein Coding	1
25	ST8SIA2	ST8 Alpha-N-Acetyl-Neuraminide Alpha-2,8-Sialyltransferase 2	Protein Coding	1
26	ST3GAL4	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 4	Protein Coding	1

Disorders associated with superpathway of glycosphingolipids biosynthesis SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Blood group, p1pk system	Enrichment	A4GALT, B3GALNT1	6.41
2	Bombay phenotype	Enrichment	FUT1, FUT2	6.41
3	Blood group, globoside system	Enrichment	B3GALNT1	3.18
4	Spastic paraplegia 26, autosomal recessive	Enrichment	B4GALNT1	3.18
5	Intellectual developmental disorder, autosomal recessive 12	Enrichment	ST3GAL3	3.18
6	St3gal3-cdg	Enrichment	ST3GAL3	3.18
7	Congenital disorder of glycosylation, type iid	Enrichment	B4GALT1	3.13
8	Combined low ldl and fibrinogen	Enrichment	B4GALT1	3.13
9	Salt and pepper developmental regression syndrome	Enrichment	ST3GAL5	2.93
10	Vitamin b12 plasma level quantitative trait locus 1	Enrichment	FUT2	2.93
11	Salt and pepper syndrome	Enrichment	ST3GAL5	2.93
12	Developmental and epileptic encephalopathy 15	Enrichment	ST3GAL3	2.88
13	Caffey disease	Enrichment	A4GALT	2.70
14	Variegate porphyria	Enrichment	B4GALT3	2.43
15	Developmental and epileptic encephalopathy	Enrichment	ST3GAL3	1.63

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

superpathway of glycosphingolipids biosynthesis

Pathway Network for superpathway of glycosphingolipids biosynthesis

Pathway network for the superpathway of glycosphingolipids biosynthesis SuperPath

Member Pathways for superpathway of glycosphingolipids biosynthesis

Pathways in the superpathway of glycosphingolipids biosynthesis SuperPath

Gene overlap in member pathways for superpathway of glycosphingolipids biosynthesis SuperPath

Associated Genes for superpathway of glycosphingolipids biosynthesis

Associated Disorders for superpathway of glycosphingolipids biosynthesis

Disorders associated with superpathway of glycosphingolipids biosynthesis SuperPath

STRING Interaction Network for superpathway of glycosphingolipids biosynthesis

Sources for superpathway of glycosphingolipids biosynthesis