Supression of HMGB1 mediated inflammation by THBD

No Pathway Network information available for Supression of HMGB1 mediated inflammation by THBD

#	Name	Source	Genes
1	Supression of HMGB1 mediated inflammation by THBD	WikiPathways	AGER HMGB1 NFKB1 NFKBIA THBD

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	THBD	Thrombomodulin	Protein Coding	1
2	NFKBIA	NFKB Inhibitor Alpha	Protein Coding	1
3	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
4	HMGB1	High Mobility Group Box 1	Protein Coding	1
5	AGER	Advanced Glycosylation End-Product Specific Receptor	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Brachyphalangy, polydactyly, and tibial aplasia/hypoplasia	Enrichment	HMGB1	3.43
2	Hemolytic uremic syndrome, atypical 6	Enrichment	THBD	3.43
3	Thrombophilia due to thrombomodulin defect	Enrichment	THBD	3.43
4	Ectodermal dysplasia and immunodeficiency 2	Enrichment	NFKBIA	3.13
5	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	3.13
6	Ectodermal dysplasia and immune deficiency	Enrichment	NFKBIA	3.13
7	Common variable immunodeficiency 12	Enrichment	NFKB1	3.13
8	Nasopharyngeal carcinoma	Enrichment	NFKBIA	2.96
9	Atypical hemolytic uremic syndrome with complement gene abnormality	Enrichment	THBD	2.66
10	Common variable immunodeficiency	Enrichment	NFKB1	2.59
11	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	2.43
12	Gliosarcoma	Enrichment	NFKBIA	2.23
13	Giant cell glioblastoma	Enrichment	NFKBIA	2.20
14	Thrombocytopenia	Enrichment	THBD	1.76

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Supression of HMGB1 mediated inflammation by THBD