Sweet Taste Signaling

Pathway network for the Sweet Taste Signaling SuperPath

Sources:

QIAGEN

Pathways in the Sweet Taste Signaling SuperPath

#	Name	Source	Genes
1	Sweet Taste Signaling	QIAGEN	ADCY1 ADCY2 ADCY3 CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CALM1 CALM2 CALM3 GNA11 GNA12 GNA13 GNA14 GNA15 GNAL GNB1 GNB2 GNB3 GNB4 GNB5 GNG2 GNG3 GNG4 KCMF1 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK2 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9 KCNRG KCNT1 KCNT2 KCNU1 KCNV1 KCNV2 KCTD1 KCTD10 KCTD11 KCTD12 KCTD13 KCTD14 KCTD15 KCTD2 KCTD3 KCTD4 KCTD5 KCTD6 KCTD7 KCTD8 KCTD9 PDE1A PDE1B PDE1C PDE2A PDE3A PDE3B PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 TAS1R2 TAS1R3 (see all 119) (see less)
2	Sperm Motility	QIAGEN	ADCY1 ADCY10 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 AURKA AURKB AURKC B4GALT1 B4GALT3 B4GALT4 B4GALT5 B4GALT6 B4GALT7 BRSK2 CACNA1G CACNA1H CACNA1I CALM1 CALM2 CALM3 CATSPER1 CATSPER2 CDK7 CDKL5 CIT CNGA1 CNGA3 CNGA4 CNGB1 CNGB3 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRQ GABRR1 GABRR2 GABRR3 GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GPLD1 GUCY1A1 GUCY1A2 GUCY1B1 GUCY2C GUCY2D GUCY2EP GUCY2F HCN1 HCN2 HCN3 HCN4 ITPR1 ITPR2 ITPR3 KCMF1 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK2 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9 KCNRG KCNT1 KCNT2 KCNU1 KCNV1 KCNV2 KCTD1 KCTD10 KCTD11 KCTD12 KCTD13 KCTD14 KCTD15 KCTD2 KCTD3 KCTD4 KCTD5 KCTD6 KCTD7 KCTD8 KCTD9 MAP3K11 MST1R NEK4 NPR1 NPR2 PDE1A PDE1B PDE1C PDE2A PDE3A PDE3B PDE4A PDE4B PDE4C PDE4D PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4C PLA2G4D PLA2G5 PLA2G6 PLA2G7 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PLD1 PLD2 PLD3 PLK4 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 PRKG1 PRKG2 PTK2 PTK2B PTK6 PTK7 RPS6KB1 SLC9A5 SLC9A9 SRPK3 STK10 STK11 STK16 STK17A STK17B STK24 STK25 STK3 STK31 STK32A STK32B STK32C STK33 STK35 STK36 STK38 STK39 STK4 STK40 TSSK1B TSSK2 TSSK3 TSSK4 TSSK6 TWF1 TXK WHR1 ZAN ZP3 (see all 236) (see less)
3	Cellular Effects of Sildenafil	QIAGEN	ACTA1 ACTA2 ACTB ACTG1 ACTG2 ADCY1 ADCY10 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CALM1 CALM2 CALM3 CLEC18C CNGA1 CNGA3 CNGA4 CNGB1 CNGB3 GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GUCY1A1 GUCY1A2 GUCY1B1 GUCY2C GUCY2D GUCY2EP GUCY2F ITPR1 ITPR2 ITPR3 KCMF1 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK2 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9 KCNRG KCNT1 KCNT2 KCNU1 KCNV1 KCNV2 KCTD1 KCTD10 KCTD11 KCTD12 KCTD13 KCTD14 KCTD15 KCTD2 KCTD3 KCTD4 KCTD5 KCTD6 KCTD7 KCTD8 KCTD9 MYH1 MYH10 MYH11 MYH13 MYH14 MYH15 MYH2 MYH3 MYH4 MYH6 MYH7 MYH7B MYH8 MYH9 MYL1 MYL11 MYL2 MYL3 MYL4 MYL5 MYL6 MYL7 MYL9 MYLK MYO10 MYO15A MYO18B MYO1A MYO1B MYO1C MYO1D MYO1E MYO1F MYO1G MYO3A MYO3B MYO5A MYO5C MYO6 MYO7A MYO9A MYO9B NOS1 NOS3 NPR1 NPR2 PDE1A PDE1B PDE1C PDE2A PDE3A PDE3B PDE4A PDE4B PDE4C PDE4D PDE5A PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PPP1CB PPP1R12A PPP1R12B PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKG1 PRKG2 (see all 194) (see less)
4	Melatonin Signaling	QIAGEN	ARAF BRAF CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CALM1 CALM2 CALM3 CAMK2A CAMK2B CAMK2D CAMK2G FOS GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG2 GNG3 GNG4 GNRH1 GNRH2 JUN KCMF1 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK2 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9 KCNRG KCNT1 KCNT2 KCNU1 KCNV1 KCNV2 KCTD1 KCTD10 KCTD11 KCTD12 KCTD13 KCTD14 KCTD15 KCTD2 KCTD3 KCTD4 KCTD5 KCTD6 KCTD7 KCTD8 KCTD9 MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MTNR1A MTNR1B PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 RAF1 RORA RORB RORC SLC2A4 (see all 140) (see less)
5	Bitter Taste Signaling	QIAGEN	GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG13 KCMF1 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK2 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9 KCNRG KCNT1 KCNT2 KCNU1 KCNV1 KCNV2 KCTD1 KCTD10 KCTD11 KCTD12 KCTD13 KCTD14 KCTD15 KCTD2 KCTD3 KCTD4 KCTD5 KCTD6 KCTD7 KCTD8 KCTD9 PDE1A PDE1B PDE1C PDE2A PDE3A PDE3B PLCB1 PLCB2 PLCB3 PLCB4 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 TAS2R1 TAS2R10 TAS2R13 TAS2R14 TAS2R16 TAS2R3 TAS2R30 TAS2R31 TAS2R33 TAS2R36 TAS2R37P TAS2R38 TAS2R4 TAS2R41 TAS2R42 TAS2R43 TAS2R5 TAS2R7 TAS2R8 TAS2R9 (see all 84) (see less)

Gene overlap in member pathways for Sweet Taste Signaling SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	GNB1	G Protein Subunit Beta 1	Protein Coding	5
2	GNB2	G Protein Subunit Beta 2	Protein Coding	5
3	GNB3	G Protein Subunit Beta 3	Protein Coding	5
4	GNB4	G Protein Subunit Beta 4	Protein Coding	5
5	GNB5	G Protein Subunit Beta 5	Protein Coding	5
6	KCMF1	Potassium Channel Modulatory Factor 1	Protein Coding	5
7	KCNK1	Potassium Two Pore Domain Channel Subfamily K Member 1	Protein Coding	5
8	KCNK10	Potassium Two Pore Domain Channel Subfamily K Member 10	Protein Coding	5
9	KCNK12	Potassium Two Pore Domain Channel Subfamily K Member 12	Protein Coding	5
10	KCNK13	Potassium Two Pore Domain Channel Subfamily K Member 13	Protein Coding	5
11	KCNK15	Potassium Two Pore Domain Channel Subfamily K Member 15	Protein Coding	5
12	KCNK16	Potassium Two Pore Domain Channel Subfamily K Member 16	Protein Coding	5
13	KCNK17	Potassium Two Pore Domain Channel Subfamily K Member 17	Protein Coding	5
14	KCNK2	Potassium Two Pore Domain Channel Subfamily K Member 2	Protein Coding	5
15	KCNK3	Potassium Two Pore Domain Channel Subfamily K Member 3	Protein Coding	5
16	KCNK4	Potassium Two Pore Domain Channel Subfamily K Member 4	Protein Coding	5
17	KCNK5	Potassium Two Pore Domain Channel Subfamily K Member 5	Protein Coding	5
18	KCNK6	Potassium Two Pore Domain Channel Subfamily K Member 6	Protein Coding	5
19	KCNK7	Potassium Two Pore Domain Channel Subfamily K Member 7	Protein Coding	5
20	KCNK9	Potassium Two Pore Domain Channel Subfamily K Member 9	Protein Coding	5
21	KCNRG	Potassium Channel Regulator	Protein Coding	5
22	KCNT1	Potassium Sodium-Activated Channel Subfamily T Member 1	Protein Coding	5
23	KCNU1	Potassium Calcium-Activated Channel Subfamily U Member 1	Protein Coding	5
24	KCNV1	Potassium Voltage-Gated Channel Modifier Subfamily V Member 1	Protein Coding	5
25	KCNV2	Potassium Voltage-Gated Channel Modifier Subfamily V Member 2	Protein Coding	5
26	KCTD1	Potassium Channel Tetramerization Domain Containing 1	Protein Coding	5
27	KCTD10	Potassium Channel Tetramerization Domain Containing 10	Protein Coding	5
28	KCTD11	Potassium Channel Tetramerization Domain Containing 11	Protein Coding	5
29	KCTD12	Potassium Channel Tetramerization Domain Containing 12	Protein Coding	5
30	KCTD13	Potassium Channel Tetramerization Domain Containing 13	Protein Coding	5
31	KCTD14	Potassium Channel Tetramerization Domain Containing 14	Protein Coding	5
32	KCTD15	Potassium Channel Tetramerization Domain Containing 15	Protein Coding	5
33	KCTD2	Potassium Channel Tetramerization Domain Containing 2	Protein Coding	5
34	KCTD3	Potassium Channel Tetramerization Domain Containing 3	Protein Coding	5
35	KCTD4	Potassium Channel Tetramerization Domain Containing 4	Protein Coding	5
36	KCTD5	Potassium Channel Tetramerization Domain Containing 5	Protein Coding	5
37	KCTD6	Potassium Channel Tetramerization Domain Containing 6	Protein Coding	5
38	KCTD7	Potassium Channel Tetramerization Domain Containing 7	Protein Coding	5
39	KCTD8	Potassium Channel Tetramerization Domain Containing 8	Protein Coding	5
40	KCTD9	Potassium Channel Tetramerization Domain Containing 9	Protein Coding	5
41	PLCB1	Phospholipase C Beta 1	Protein Coding	5
42	PLCB2	Phospholipase C Beta 2	Protein Coding	5
43	PLCB3	Phospholipase C Beta 3	Protein Coding	5
44	PLCB4	Phospholipase C Beta 4	Protein Coding	5
45	KCNT2	Potassium Sodium-Activated Channel Subfamily T Member 2	Protein Coding	5
46	CACNA1G	Calcium Voltage-Gated Channel Subunit Alpha1 G	Protein Coding	4
47	CACNA1H	Calcium Voltage-Gated Channel Subunit Alpha1 H	Protein Coding	4
48	CACNA1I	Calcium Voltage-Gated Channel Subunit Alpha1 I	Protein Coding	4
49	CALM1	Calmodulin 1	Protein Coding	4
50	CALM2	Calmodulin 2	Protein Coding	4
51	CALM3	Calmodulin 3	Protein Coding	4
52	GNG2	G Protein Subunit Gamma 2	Protein Coding	4
53	GNG3	G Protein Subunit Gamma 3	Protein Coding	4
54	GNG4	G Protein Subunit Gamma 4	Protein Coding	4
55	PDE1A	Phosphodiesterase 1A	Protein Coding	4
56	PDE1B	Phosphodiesterase 1B	Protein Coding	4
57	PDE1C	Phosphodiesterase 1C	Protein Coding	4
58	PDE2A	Phosphodiesterase 2A	Protein Coding	4
59	PDE3A	Phosphodiesterase 3A	Protein Coding	4
60	PDE3B	Phosphodiesterase 3B	Protein Coding	4
61	PLCD1	Phospholipase C Delta 1	Protein Coding	4
62	PLCD3	Phospholipase C Delta 3	Protein Coding	4
63	PLCD4	Phospholipase C Delta 4	Protein Coding	4
64	PLCE1	Phospholipase C Epsilon 1	Protein Coding	4
65	PLCG1	Phospholipase C Gamma 1	Protein Coding	4
66	PLCG2	Phospholipase C Gamma 2	Protein Coding	4
67	PLCZ1	Phospholipase C Zeta 1	Protein Coding	4
68	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	4
69	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	4
70	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	4
71	PRKAR1A	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha	Protein Coding	4
72	PRKAR1B	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Beta	Protein Coding	4
73	PRKAR2A	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha	Protein Coding	4
74	PRKAR2B	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Beta	Protein Coding	4
75	PRKCA	Protein Kinase C Alpha	Protein Coding	4
76	PRKCB	Protein Kinase C Beta	Protein Coding	4
77	PRKCD	Protein Kinase C Delta	Protein Coding	4
78	PRKCE	Protein Kinase C Epsilon	Protein Coding	4
79	PRKCG	Protein Kinase C Gamma	Protein Coding	4
80	PRKCH	Protein Kinase C Eta	Protein Coding	4
81	PRKCI	Protein Kinase C Iota	Protein Coding	4
82	PRKD1	Protein Kinase D1	Protein Coding	4
83	PRKD3	Protein Kinase D3	Protein Coding	4
84	PRKCQ	Protein Kinase C Theta	Protein Coding	4
85	PRKCZ	Protein Kinase C Zeta	Protein Coding	4
86	ADCY1	Adenylate Cyclase 1	Protein Coding	3
87	ADCY2	Adenylate Cyclase 2	Protein Coding	3
88	ADCY3	Adenylate Cyclase 3	Protein Coding	3
89	CACNA1A	Calcium Voltage-Gated Channel Subunit Alpha1 A	Protein Coding	3
90	CACNA1B	Calcium Voltage-Gated Channel Subunit Alpha1 B	Protein Coding	3
91	CACNA1C	Calcium Voltage-Gated Channel Subunit Alpha1 C	Protein Coding	3
92	CACNA1D	Calcium Voltage-Gated Channel Subunit Alpha1 D	Protein Coding	3
93	CACNA1E	Calcium Voltage-Gated Channel Subunit Alpha1 E	Protein Coding	3
94	CACNA1F	Calcium Voltage-Gated Channel Subunit Alpha1 F	Protein Coding	3
95	CACNA1S	Calcium Voltage-Gated Channel Subunit Alpha1 S	Protein Coding	3
96	CACNA2D1	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 1	Protein Coding	3
97	CACNA2D2	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 2	Protein Coding	3
98	CACNA2D3	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 3	Protein Coding	3
99	CACNA2D4	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 4	Protein Coding	3
100	CACNB1	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 1	Protein Coding	3
101	CACNB2	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 2	Protein Coding	3
102	CACNB3	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 3	Protein Coding	3
103	CACNB4	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 4	Protein Coding	3
104	CACNG1	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 1	Protein Coding	3
105	CACNG2	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 2	Protein Coding	3
106	CACNG3	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 3	Protein Coding	3
107	CACNG4	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 4	Protein Coding	3
108	CACNG5	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 5	Protein Coding	3
109	CACNG6	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 6	Protein Coding	3
110	CACNG7	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 7	Protein Coding	3
111	CACNG8	Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 8	Protein Coding	3
112	GNA11	G Protein Subunit Alpha 11	Protein Coding	3
113	GNA12	G Protein Subunit Alpha 12	Protein Coding	3
114	GNA13	G Protein Subunit Alpha 13	Protein Coding	3
115	GNA14	G Protein Subunit Alpha 14	Protein Coding	3
116	GNA15	G Protein Subunit Alpha 15	Protein Coding	3
117	GNAL	G Protein Subunit Alpha L	Protein Coding	3
118	GNAS	GNAS Complex Locus	Protein Coding	3
119	GNG13	G Protein Subunit Gamma 13	Protein Coding	3
120	ADCY4	Adenylate Cyclase 4	Protein Coding	2
121	ADCY5	Adenylate Cyclase 5	Protein Coding	2
122	ADCY6	Adenylate Cyclase 6	Protein Coding	2
123	ADCY7	Adenylate Cyclase 7	Protein Coding	2
124	ADCY8	Adenylate Cyclase 8	Protein Coding	2
125	ADCY9	Adenylate Cyclase 9	Protein Coding	2
126	CNGA1	Cyclic Nucleotide Gated Channel Subunit Alpha 1	Protein Coding	2
127	CNGA3	Cyclic Nucleotide Gated Channel Subunit Alpha 3	Protein Coding	2
128	CNGA4	Cyclic Nucleotide Gated Channel Subunit Alpha 4	Protein Coding	2
129	CNGB1	Cyclic Nucleotide Gated Channel Subunit Beta 1	Protein Coding	2
130	CNGB3	Cyclic Nucleotide Gated Channel Subunit Beta 3	Protein Coding	2
131	GNAI1	G Protein Subunit Alpha I1	Protein Coding	2
132	GNAI2	G Protein Subunit Alpha I2	Protein Coding	2
133	GNAI3	G Protein Subunit Alpha I3	Protein Coding	2
134	GNG10	G Protein Subunit Gamma 10	Protein Coding	2
135	GNG11	G Protein Subunit Gamma 11	Protein Coding	2
136	GNG12	G Protein Subunit Gamma 12	Protein Coding	2
137	GNG5	G Protein Subunit Gamma 5	Protein Coding	2
138	GNG7	G Protein Subunit Gamma 7	Protein Coding	2
139	GNG8	G Protein Subunit Gamma 8	Protein Coding	2
140	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	2
141	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	2
142	GUCY1A2	Guanylate Cyclase 1 Soluble Subunit Alpha 2	Protein Coding	2
143	GUCY1A1	Guanylate Cyclase 1 Soluble Subunit Alpha 1	Protein Coding	2
144	GUCY1B1	Guanylate Cyclase 1 Soluble Subunit Beta 1	Protein Coding	2
145	GUCY2C	Guanylate Cyclase 2C	Protein Coding	2
146	GUCY2D	Guanylate Cyclase 2D, Retinal	Protein Coding	2
147	GUCY2EP	Guanylate Cyclase 2E, Pseudogene	Pseudogene	2
148	GUCY2F	Guanylate Cyclase 2F, Retinal	Protein Coding	2
149	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	2
150	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	2
151	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	2
152	NPR1	Natriuretic Peptide Receptor 1	Protein Coding	2
153	NPR2	Natriuretic Peptide Receptor 2	Protein Coding	2
154	PDE4A	Phosphodiesterase 4A	Protein Coding	2
155	PDE4B	Phosphodiesterase 4B	Protein Coding	2
156	PDE4C	Phosphodiesterase 4C	Protein Coding	2
157	PDE4D	Phosphodiesterase 4D	Protein Coding	2
158	PRKG1	Protein Kinase CGMP-Dependent 1	Protein Coding	2
159	PRKG2	Protein Kinase CGMP-Dependent 2	Protein Coding	2
160	ADCY10	Adenylate Cyclase 10	Protein Coding	2
161	TAS1R2	Taste 1 Receptor Member 2	Protein Coding	1
162	TAS1R3	Taste 1 Receptor Member 3	Protein Coding	1
163	AURKB	Aurora Kinase B	Protein Coding	1
164	AURKC	Aurora Kinase C	Protein Coding	1
165	B4GALT1	Beta-1,4-Galactosyltransferase 1	Protein Coding	1
166	B4GALT3	Beta-1,4-Galactosyltransferase 3	Protein Coding	1
167	B4GALT4	Beta-1,4-Galactosyltransferase 4	Protein Coding	1
168	B4GALT5	Beta-1,4-Galactosyltransferase 5	Protein Coding	1
169	B4GALT6	Beta-1,4-Galactosyltransferase 6	Protein Coding	1
170	B4GALT7	Beta-1,4-Galactosyltransferase 7	Protein Coding	1
171	TSSK4	Testis Specific Serine Kinase 4	Protein Coding	1
172	CATSPER1	Cation Channel Sperm Associated 1	Protein Coding	1
173	CATSPER2	Cation Channel Sperm Associated 2	Protein Coding	1
174	CDK7	Cyclin Dependent Kinase 7	Protein Coding	1
175	CDKL5	Cyclin Dependent Kinase Like 5	Protein Coding	1
176	CIT	Citron Rho-Interacting Serine/Threonine Kinase	Protein Coding	1
177	GABRA1	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha1	Protein Coding	1
178	GABRA2	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha2	Protein Coding	1
179	GABRA3	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha3	Protein Coding	1
180	GABRA4	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha4	Protein Coding	1
181	GABRA5	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha5	Protein Coding	1
182	GABRA6	Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha6	Protein Coding	1
183	GABRB1	Gamma-Aminobutyric Acid Type A Receptor Subunit Beta1	Protein Coding	1
184	GABRB2	Gamma-Aminobutyric Acid Type A Receptor Subunit Beta2	Protein Coding	1
185	GABRB3	Gamma-Aminobutyric Acid Type A Receptor Subunit Beta3	Protein Coding	1
186	GABRD	Gamma-Aminobutyric Acid Type A Receptor Subunit Delta	Protein Coding	1
187	GABRE	Gamma-Aminobutyric Acid Type A Receptor Subunit Epsilon	Protein Coding	1
188	GABRG1	Gamma-Aminobutyric Acid Type A Receptor Subunit Gamma1	Protein Coding	1
189	GABRG2	Gamma-Aminobutyric Acid Type A Receptor Subunit Gamma2	Protein Coding	1
190	GABRG3	Gamma-Aminobutyric Acid Type A Receptor Subunit Gamma3	Protein Coding	1
191	GABRQ	Gamma-Aminobutyric Acid Type A Receptor Subunit Theta	Protein Coding	1
192	GABRR1	Gamma-Aminobutyric Acid Type A Receptor Subunit Rho1	Protein Coding	1
193	GABRR2	Gamma-Aminobutyric Acid Type A Receptor Subunit Rho2	Protein Coding	1
194	GABRR3	Gamma-Aminobutyric Acid Type A Receptor Subunit Rho3	Protein Coding	1
195	GNAO1	G Protein Subunit Alpha O1	Protein Coding	1
196	GNAZ	G Protein Subunit Alpha Z	Protein Coding	1
197	GPLD1	Glycosylphosphatidylinositol Specific Phospholipase D1	Protein Coding	1
198	HCN1	Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 1	Protein Coding	1
199	HCN2	Hyperpolarization Activated Cyclic Nucleotide Gated Potassium And Sodium Channel 2	Protein Coding	1
200	HCN3	Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 3	Protein Coding	1
201	HCN4	Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4	Protein Coding	1
202	STK32B	Serine/Threonine Kinase 32B	Protein Coding	1
203	MAP3K11	Mitogen-Activated Protein Kinase Kinase Kinase 11	Protein Coding	1
204	STK32A	Serine/Threonine Kinase 32A	Protein Coding	1
205	STK40	Serine/Threonine Kinase 40	Protein Coding	1
206	MST1R	Macrophage Stimulating 1 Receptor	Protein Coding	1
207	NEK4	NIMA Related Kinase 4	Protein Coding	1
208	STK32C	Serine/Threonine Kinase 32C	Protein Coding	1
209	PLA2G10	Phospholipase A2 Group X	Protein Coding	1
210	PLA2G12A	Phospholipase A2 Group XIIA	Protein Coding	1
211	PLA2G12B	Phospholipase A2 Group XIIB	Protein Coding	1
212	PLA2G1B	Phospholipase A2 Group IB	Protein Coding	1
213	PLA2G2A	Phospholipase A2 Group IIA	Protein Coding	1
214	PLA2G2D	Phospholipase A2 Group IID	Protein Coding	1
215	PLA2G2E	Phospholipase A2 Group IIE	Protein Coding	1
216	PLA2G2F	Phospholipase A2 Group IIF	Protein Coding	1
217	PLA2G3	Phospholipase A2 Group III	Protein Coding	1
218	PLA2G4A	Phospholipase A2 Group IVA	Protein Coding	1
219	PLA2G4C	Phospholipase A2 Group IVC	Protein Coding	1
220	PLA2G4D	Phospholipase A2 Group IVD	Protein Coding	1
221	PLA2G5	Phospholipase A2 Group V	Protein Coding	1
222	PLA2G6	Phospholipase A2 Group VI	Protein Coding	1
223	PLA2G7	Phospholipase A2 Group VII	Protein Coding	1
224	PLD1	Phospholipase D1	Protein Coding	1
225	PLD2	Phospholipase D2	Protein Coding	1
226	PLD3	Phospholipase D Family Member 3	Protein Coding	1
227	PLK4	Polo Like Kinase 4	Protein Coding	1
228	PTK2	Protein Tyrosine Kinase 2	Protein Coding	1
229	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	1
230	PTK6	Protein Tyrosine Kinase 6	Protein Coding	1
231	PTK7	Protein Tyrosine Kinase 7 (Inactive)	Protein Coding	1
232	TWF1	Twinfilin Actin Binding Protein 1	Protein Coding	1
233	RPS6KB1	Ribosomal Protein S6 Kinase B1	Protein Coding	1
234	SLC9A5	Solute Carrier Family 9 Member A5	Protein Coding	1
235	SLC9A9	Solute Carrier Family 9 Member A9	Protein Coding	1
236	TSSK6	Testis Specific Serine Kinase 6	Protein Coding	1
237	STK10	Serine/Threonine Kinase 10	Protein Coding	1
238	STK11	Serine/Threonine Kinase 11	Protein Coding	1
239	STK16	Serine/Threonine Kinase 16	Protein Coding	1
240	STK17A	Serine/Threonine Kinase 17a	Protein Coding	1
241	STK17B	Serine/Threonine Kinase 17b	Protein Coding	1
242	WHR1	Winged Helix Repair Factor 1	Protein Coding	1
243	TSSK2	Testis Specific Serine Kinase 2	Protein Coding	1
244	TSSK3	Testis Specific Serine Kinase 3	Protein Coding	1
245	TSSK1B	Testis Specific Serine Kinase 1B	Protein Coding	1
246	SRPK3	SRSF Protein Kinase 3	Protein Coding	1
247	STK24	Serine/Threonine Kinase 24	Protein Coding	1
248	STK25	Serine/Threonine Kinase 25	Protein Coding	1
249	BRSK2	BR Serine/Threonine Kinase 2	Protein Coding	1
250	STK3	Serine/Threonine Kinase 3	Protein Coding	1
251	STK31	Serine/Threonine Kinase 31	Protein Coding	1
252	STK33	Serine/Threonine Kinase 33	Protein Coding	1
253	STK35	Serine/Threonine Kinase 35	Protein Coding	1
254	STK36	Serine/Threonine Kinase 36	Protein Coding	1
255	STK38	Serine/Threonine Kinase 38	Protein Coding	1
256	STK39	Serine/Threonine Kinase 39	Protein Coding	1
257	STK4	Serine/Threonine Kinase 4	Protein Coding	1
258	AURKA	Aurora Kinase A	Protein Coding	1
259	TXK	TXK Tyrosine Kinase	Protein Coding	1
260	ZAN	Zonadhesin	Protein Coding	1
261	ZP3	Zona Pellucida Glycoprotein 3	Protein Coding	1
262	ACTA1	Actin Alpha 1, Skeletal Muscle	Protein Coding	1
263	ACTA2	Actin Alpha 2, Smooth Muscle	Protein Coding	1
264	ACTB	Actin Beta	Protein Coding	1
265	ACTG1	Actin Gamma 1	Protein Coding	1
266	ACTG2	Actin Gamma 2, Smooth Muscle	Protein Coding	1
267	MYL11	Myosin Light Chain 11	Protein Coding	1
268	MYH15	Myosin Heavy Chain 15	Protein Coding	1
269	CLEC18C	C-Type Lectin Domain Family 18 Member C	Protein Coding	1
270	MYH1	Myosin Heavy Chain 1	Protein Coding	1
271	MYH10	Myosin Heavy Chain 10	Protein Coding	1
272	MYH11	Myosin Heavy Chain 11	Protein Coding	1
273	MYH13	Myosin Heavy Chain 13	Protein Coding	1
274	MYH14	Myosin Heavy Chain 14	Protein Coding	1
275	MYH2	Myosin Heavy Chain 2	Protein Coding	1
276	MYH3	Myosin Heavy Chain 3	Protein Coding	1
277	MYH4	Myosin Heavy Chain 4	Protein Coding	1
278	MYH6	Myosin Heavy Chain 6	Protein Coding	1
279	MYH7	Myosin Heavy Chain 7	Protein Coding	1
280	MYH7B	Myosin Heavy Chain 7B	Protein Coding	1
281	MYH8	Myosin Heavy Chain 8	Protein Coding	1
282	MYH9	Myosin Heavy Chain 9	Protein Coding	1
283	MYL1	Myosin Light Chain 1	Protein Coding	1
284	MYL2	Myosin Light Chain 2	Protein Coding	1
285	MYL3	Myosin Light Chain 3	Protein Coding	1
286	MYL4	Myosin Light Chain 4	Protein Coding	1
287	MYL5	Myosin Light Chain 5	Protein Coding	1
288	MYL6	Myosin Light Chain 6	Protein Coding	1
289	MYL7	Myosin Light Chain 7	Protein Coding	1
290	MYL9	Myosin Light Chain 9	Protein Coding	1
291	MYLK	Myosin Light Chain Kinase	Protein Coding	1
292	MYO10	Myosin X	Protein Coding	1
293	MYO15A	Myosin XVA	Protein Coding	1
294	MYO18B	Myosin XVIIIB	Protein Coding	1
295	MYO1A	Myosin IA	Protein Coding	1
296	MYO1B	Myosin IB	Protein Coding	1
297	MYO1C	Myosin IC	Protein Coding	1
298	MYO1D	Myosin ID	Protein Coding	1
299	MYO1E	Myosin IE	Protein Coding	1
300	MYO1F	Myosin IF	Protein Coding	1
301	MYO1G	Myosin IG	Protein Coding	1
302	MYO3A	Myosin IIIA	Protein Coding	1
303	MYO3B	Myosin IIIB	Protein Coding	1
304	MYO5A	Myosin VA	Protein Coding	1
305	MYO5C	Myosin VC	Protein Coding	1
306	MYO6	Myosin VI	Protein Coding	1
307	MYO7A	Myosin VIIA	Protein Coding	1
308	MYO9A	Myosin IXA	Protein Coding	1
309	MYO9B	Myosin IXB	Protein Coding	1
310	NOS1	Nitric Oxide Synthase 1	Protein Coding	1
311	NOS3	Nitric Oxide Synthase 3	Protein Coding	1
312	PDE5A	Phosphodiesterase 5A	Protein Coding	1
313	PPP1CB	Protein Phosphatase 1 Catalytic Subunit Beta	Protein Coding	1
314	PPP1R12A	Protein Phosphatase 1 Regulatory Subunit 12A	Protein Coding	1
315	PPP1R12B	Protein Phosphatase 1 Regulatory Subunit 12B	Protein Coding	1
316	ARAF	A-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
317	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
318	CAMK2A	Calcium/Calmodulin Dependent Protein Kinase II Alpha	Protein Coding	1
319	CAMK2B	Calcium/Calmodulin Dependent Protein Kinase II Beta	Protein Coding	1
320	CAMK2D	Calcium/Calmodulin Dependent Protein Kinase II Delta	Protein Coding	1
321	CAMK2G	Calcium/Calmodulin Dependent Protein Kinase II Gamma	Protein Coding	1
322	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
323	GNRH1	Gonadotropin Releasing Hormone 1	Protein Coding	1
324	GNRH2	Gonadotropin Releasing Hormone 2	Protein Coding	1
325	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
326	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
327	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	1
328	MAP2K3	Mitogen-Activated Protein Kinase Kinase 3	Protein Coding	1
329	MAP2K4	Mitogen-Activated Protein Kinase Kinase 4	Protein Coding	1
330	MAP2K5	Mitogen-Activated Protein Kinase Kinase 5	Protein Coding	1
331	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	1
332	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
333	MAPK10	Mitogen-Activated Protein Kinase 10	Protein Coding	1
334	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
335	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	1
336	MAPK9	Mitogen-Activated Protein Kinase 9	Protein Coding	1
337	MTNR1A	Melatonin Receptor 1A	Protein Coding	1
338	MTNR1B	Melatonin Receptor 1B	Protein Coding	1
339	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
340	RORA	RAR Related Orphan Receptor A	Protein Coding	1
341	RORB	RAR Related Orphan Receptor B	Protein Coding	1
342	RORC	RAR Related Orphan Receptor C	Protein Coding	1
343	SLC2A4	Solute Carrier Family 2 Member 4	Protein Coding	1
344	GNAT3	G Protein Subunit Alpha Transducin 3	Protein Coding	1
345	TAS2R42	Taste 2 Receptor Member 42	Protein Coding	1
346	TAS2R1	Taste 2 Receptor Member 1	Protein Coding	1
347	TAS2R10	Taste 2 Receptor Member 10	Protein Coding	1
348	TAS2R13	Taste 2 Receptor Member 13	Protein Coding	1
349	TAS2R14	Taste 2 Receptor Member 14	Protein Coding	1
350	TAS2R16	Taste 2 Receptor Member 16	Protein Coding	1
351	TAS2R3	Taste 2 Receptor Member 3	Protein Coding	1
352	TAS2R30	Taste 2 Receptor Member 30	Protein Coding	1
353	TAS2R31	Taste 2 Receptor Member 31	Protein Coding	1
354	TAS2R33	Taste 2 Receptor Member 33	Protein Coding	1
355	TAS2R36	Taste 2 Receptor Member 36	Protein Coding	1
356	TAS2R37P	Taste 2 Receptor Member 37, Pseudogene	Pseudogene	1
357	TAS2R38	Taste 2 Receptor Member 38	Protein Coding	1
358	TAS2R4	Taste 2 Receptor Member 4	Protein Coding	1
359	TAS2R41	Taste 2 Receptor Member 41	Protein Coding	1
360	TAS2R43	Taste 2 Receptor Member 43	Protein Coding	1
361	TAS2R5	Taste 2 Receptor Member 5	Protein Coding	1
362	TAS2R7	Taste 2 Receptor Member 7	Protein Coding	1
363	TAS2R8	Taste 2 Receptor Member 8	Protein Coding	1
364	TAS2R9	Taste 2 Receptor Member 9	Protein Coding	1

Disorders associated with Sweet Taste Signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ACTG1, MYH14, MYH9, MYO1A, MYO1C, MYO6, MYO7A, PDE1C	6.18
2	Cone-rod dystrophy 6	Enrichment	CACNA1F, CACNA2D4, CNGB3, GUCY2D, KCNV2	5.99
3	Childhood absence epilepsy	Enrichment	CACNA1H, GABRA1, GABRB3, GABRG2	5.88
4	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF, MAP2K1, MAP2K2	5.37
5	Cardiofaciocutaneous syndrome	Enrichment	BRAF, MAP2K1, MAP2K2	5.37
6	Non-syndromic genetic deafness	Enrichment	ACTG1, MYH14, MYO15A, MYO3A, MYO6, MYO7A	4.97
7	Megacystis-microcolon-intestinal hypoperistalsis syndrome 1	Enrichment	ACTG2, MYH11, MYLK	4.94
8	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF, MAP2K1, MAP2K2, RAF1	4.87
9	Nonsyndromic hearing loss	Enrichment	ACTG1, MYH14, MYO15A, MYO3A, MYO6, MYO7A	4.57
10	Visceral myopathy 1	Enrichment	ACTG2, MYH11, MYLK	4.55
11	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	4.45
12	Cone-rod dystrophy 2	Enrichment	CACNA1F, CACNA2D4, CNGA1, CNGA3, CNGB3, GUCY2D, KCNV2	4.29
13	Long qt syndrome 1	Enrichment	CACNA1C, CALM1, CALM2, CALM3, ITPR3	4.22
14	Long qt syndrome	Enrichment	CACNA1C, CACNA1S, CALM1, CALM2, MYH6	4.15
15	Noonan syndrome 1	Enrichment	BRAF, MAP2K1, MAP2K2, RAF1	4.08
16	Primary hyperaldosteronism	Enrichment	BRAF, CACNA1H, GNAS	4.06
17	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	GNAS, PRKAR1A	3.98
18	Rasopathy	Enrichment	BRAF, MAP2K1, MAP2K2, RAF1	3.87
19	Autosomal dominant non-syndromic intellectual disability	Enrichment	CACNA1I, CACNG2, CAMK2A, CAMK2B, GNB1	3.80
20	Achromatopsia 3	Enrichment	CNGA3, CNGB3	3.69
21	Acrodysostosis	Enrichment	PDE4D, PRKAR1A	3.69
22	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	3.69
23	Neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures	Enrichment	CACNA1A, CACNA1C	3.64
24	Anastomosing haemangioma	Enrichment	GNA11, GNA14	3.64
25	Langerhans cell histiocytosis	Enrichment	BRAF, MAP2K1	3.50
26	Cardiomyopathy, familial hypertrophic, 1	Enrichment	CACNA1C, MYH6, MYH7, MYH7B	3.46
27	Cone dystrophy	Enrichment	CACNA2D4, CNGA3, GUCY2D, KCNV2	3.46
28	Auriculocondylar syndrome 1	Enrichment	GNAI3, PLCB4	3.20
29	Noonan syndrome with multiple lentigines	Enrichment	BRAF, RAF1	3.20
30	Epilepsy, idiopathic generalized	Enrichment	CACNA1H, GABRA1, GABRD	3.11
31	Congenital stationary night blindness	Enrichment	CACNA1F, CACNA2D4, GNB3	2.99
32	Melanoma, uveal	Enrichment	GNA11, PLCB4	2.95
33	Congenital myopathy 4a, autosomal dominant	Enrichment	ACTA1, MYH7, MYL2	2.94
34	Carney complex variant	Enrichment	MYH8, PRKAR1A	2.92
35	Familial sick sinus syndrome	Enrichment	GNB2, MYH6	2.92
36	Developmental and epileptic encephalopathy 14	Enrichment	KCNT1, PLCB1	2.88
37	Brugada syndrome	Enrichment	CACNA1C, CACNA2D1, CACNB2	2.83
38	Eye disease	Enrichment	CACNA1F, CACNA2D4, CNGA3, CNGB3	2.82
39	Generalized epilepsy with febrile seizures plus	Enrichment	GABRD, GABRG2, HCN1	2.78
40	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	ADCY1, MYH9, MYO15A, MYO3A, MYO6, MYO7A	2.76
41	Color blindness	Enrichment	CNGA3, HCN1	2.75
42	Congenital myopathy 3 with rigid spine	Enrichment	ACTA1, MYH7	2.70
43	Pilomyxoid astrocytoma	Enrichment	BRAF, RAF1	2.67
44	Congenital myopathy	Enrichment	ACTA1, CACNA1S, MYH7	2.63
45	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	2.58
46	Undetermined early-onset epileptic encephalopathy	Enrichment	GABRA2, GABRA5, GABRB2, GABRG2, HCN1	2.55
47	Melanocytic nevus syndrome, congenital	Enrichment	BRAF, RAF1	2.55
48	Lennox-gastaut syndrome	Enrichment	CACNA1A, MAPK10	2.55
49	Moyamoya disease 1	Enrichment	ACTA2, GUCY1A1	2.53
50	Intestinal pseudo-obstruction	Enrichment	ACTG2, MYH11	2.53
51	Hypertrophic cardiomyopathy	Enrichment	MYH7, MYH7B, MYL2, MYL3	2.49
52	Optic atrophy plus syndrome	Enrichment	CACNA1F, CNGA3, CNGB3, GUCY2D	2.45
53	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	ACTA2, MYH11, MYLK, PRKG1	2.45
54	Angelman syndrome	Enrichment	CDKL5, GABRG3	2.36
55	Testicular germ cell tumor	Enrichment	STK10, STK11	2.36
56	Ear malformation	Enrichment	MYO15A, MYO6, MYO7A	2.33
57	Cerebral palsy	Enrichment	CACNA1A, CACNA1C, GNB1	2.32
58	Rare genetic deafness	Enrichment	ACTG1, MYH9, MYO15A, MYO6, MYO7A	2.26
59	Lung non-small cell carcinoma	Enrichment	BRAF, MAP2K1	2.26
60	Dystonia	Enrichment	CAMK2B, GNAL, GNB1	2.26
61	Thiourea tasting	Enrichment	TAS2R38	2.21
62	Hypertension and brachydactyly syndrome	Enrichment	PDE3A	2.21
63	Cone dystrophy with supernormal rod responses	Enrichment	KCNV2	2.21
64	Scalp-ear-nipple syndrome	Enrichment	KCTD1	2.21
65	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	2.21
66	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	2.21
67	Spondylometaphyseal dysplasia with corneal dystrophy	Enrichment	PLCB3	2.21
68	Spermatogenic failure 79	Enrichment	KCNU1	2.21
69	Auriculocondylar syndrome 2a	Enrichment	PLCB4	2.21
70	Intellectual developmental disorder with paroxysmal dyskinesia or seizures	Enrichment	PDE2A	2.21
71	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	2.21
72	Spinocerebellar ataxia 14	Enrichment	PRKCG	2.21
73	Pulmonary hypertension, primary, 4	Enrichment	KCNK3	2.21
74	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	2.21
75	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	2.21
76	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	2.21
77	Deafness, autosomal dominant 74	Enrichment	PDE1C	2.21
78	Sick sinus syndrome 4	Enrichment	GNB2	2.21
79	Developmental and epileptic encephalopathy 57	Enrichment	KCNT2	2.21
80	Beta-glucopyranoside tasting	Enrichment	TAS2R16	2.21
81	Auriculocondylar syndrome 2b	Enrichment	PLCB4	2.21
82	Progressive myoclonus epilepsy 3	Enrichment	KCTD7	2.21
83	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	2.21
84	Cone dystrophy with supernormal rod response	Enrichment	KCNV2	2.21
85	Familial thoracic aortic aneurysm and dissection	Enrichment	MYH11, MYLK	2.16
86	Choreatic disease	Enrichment	GNAO1, PDE2A	2.10
87	Nemaline myopathy	Enrichment	ACTA1, MYO18B	2.07
88	Achromatopsia	Enrichment	CNGA3, CNGB3	2.07
89	Hypocalciuric hypercalcemia, familial, type ii	Enrichment	GNA11	2.06
90	Acrodysostosis 1 with or without hormone resistance	Enrichment	PRKAR1A	2.06
91	Thyrotoxic periodic paralysis 1	Enrichment	CACNA1S	2.06
92	Epilepsy, idiopathic generalized 9	Enrichment	CACNB4	2.06
93	Carney complex, type 1	Enrichment	PRKAR1A	2.06
94	Brugada syndrome 4	Enrichment	CACNB2	2.06
95	Nail disorder, nonsyndromic congenital, 3	Enrichment	PLCD1	2.06
96	Deafness, autosomal recessive 44	Enrichment	ADCY1	2.06
97	Episodic ataxia, type 5	Enrichment	CACNB4	2.06
98	Neurodevelopmental disorder with speech impairment and with or without seizures	Enrichment	CACNA1I	2.06
99	Congenital myopathy 18	Enrichment	CACNA1S	2.06
100	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.06
101	Cone-rod dystrophy, x-linked, 3	Enrichment	CACNA1F	2.06
102	Retinal cone dystrophy 4	Enrichment	CACNA2D4	2.06
103	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	2.06
104	Myxoma, intracardiac	Enrichment	PRKAR1A	2.06
105	Primary aldosteronism, seizures, and neurologic abnormalities	Enrichment	CACNA1D	2.06
106	Brugada syndrome 3	Enrichment	CACNA1C	2.06
107	Epilepsy, childhood absence 6	Enrichment	CACNA1H	2.06
108	Malignant hyperthermia 5	Enrichment	CACNA1S	2.06
109	Intellectual developmental disorder, autosomal dominant 10	Enrichment	CACNG2	2.06
110	Sinoatrial node dysfunction and deafness	Enrichment	CACNA1D	2.06
111	Dystonia 25	Enrichment	GNAL	2.06
112	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	2.06
113	Long qt syndrome 16	Enrichment	CALM3	2.06
114	Hypocalcemia, autosomal dominant 2	Enrichment	GNA11	2.06
115	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	2.06
116	Spinocerebellar ataxia 42	Enrichment	CACNA1G	2.06
117	Developmental and epileptic encephalopathy 110	Enrichment	CACNA2D1	2.06
118	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	2.06
119	Spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits	Enrichment	CACNA1G	2.06
120	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	2.06
121	Developmental and epileptic encephalopathy 69	Enrichment	CACNA1E	2.06
122	Hyperaldosteronism, familial, type iv	Enrichment	CACNA1H	2.06
123	Long qt syndrome 15	Enrichment	CALM2	2.06
124	Prkar1b-related neurodegenerative dementia with intermediate filaments	Enrichment	PRKAR1B	2.06
125	Conn's syndrome	Enrichment	CACNA1H	2.06
126	Sporadic hemiplegic migraine	Enrichment	CACNA1A	2.06
127	Atypical timothy syndrome	Enrichment	CACNA1C	2.06
128	Aldosterone-producing adenoma with seizures and neurological abnormalities	Enrichment	CACNA1D	2.06
129	Timothy syndrome type 2	Enrichment	CACNA1C	2.06
130	Periodic paralysis with transient compartment-like syndrome	Enrichment	CACNA1S	2.06
131	Phakomatosis cesiomarmorata	Enrichment	GNA11	2.06
132	Kaposiform hemangioendothelioma	Enrichment	GNA14	2.06
133	Timothy syndrome type 1	Enrichment	CACNA1C	2.06
134	Cacna1c-related disorders	Enrichment	CACNA1C	2.06
135	Benign paroxysmal torticollis of infancy	Enrichment	CACNA1A	2.06
136	Pallister-killian syndrome	Enrichment	ARAF	1.99
137	Noonan syndrome 5	Enrichment	RAF1	1.99
138	Pseudohypoparathyroidism, type ic	Enrichment	GNAS	1.99
139	Melorheostosis, isolated	Enrichment	MAP2K1	1.99
140	Osseous heteroplasia, progressive	Enrichment	GNAS	1.99
141	Noonan syndrome 7	Enrichment	BRAF	1.99
142	Leopard syndrome 3	Enrichment	BRAF	1.99
143	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	1.99
144	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	1.99
145	Ventricular tachycardia, familial	Enrichment	GNAI2	1.99
146	Acth-independent macronodular adrenal hyperplasia 1	Enrichment	GNAS	1.99
147	Noonan syndrome 13	Enrichment	MAPK1	1.99
148	Pituitary adenoma 3, multiple types	Enrichment	GNAS	1.99
149	Intellectual developmental disorder, autosomal recessive 63	Enrichment	CAMK2A	1.99
150	Intellectual developmental disorder, autosomal dominant 54	Enrichment	CAMK2B	1.99
151	Epilepsy, idiopathic generalized 15	Enrichment	RORB	1.99
152	Neurodevelopmental disorder with hypotonia, impaired speech, and behavioral abnormalities	Enrichment	GNAI1	1.99
153	Immunodeficiency 42	Enrichment	RORC	1.99
154	Lymphangioma	Enrichment	BRAF	1.99
155	Phace association	Enrichment	BRAF	1.99
156	Melorheostosis	Enrichment	MAP2K1	1.99
157	Leopard syndrome 2	Enrichment	RAF1	1.99
158	Hypogonadotropic hypogonadism 12 with or without anosmia	Enrichment	GNRH1	1.99
159	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	1.99
160	Disorders of gnas inactivation	Enrichment	GNAS	1.99
161	Intellectual developmental disorder, autosomal dominant 53	Enrichment	CAMK2A	1.99
162	Trigonitis	Enrichment	RAF1	1.99
163	Intellectual developmental disorder, autosomal dominant 59	Enrichment	CAMK2G	1.99
164	Syringocystadenoma papilliferum	Enrichment	BRAF	1.99
165	Ganglioglioma	Enrichment	BRAF	1.99
166	Nongerminomatous germ cell tumor	Enrichment	BRAF	1.99
167	Monostotic fibrous dysplasia	Enrichment	GNAS	1.99
168	Phace syndrome	Enrichment	BRAF	1.99
169	Classic hairy cell leukemia	Enrichment	BRAF	1.99
170	Mazabraud syndrome	Enrichment	GNAS	1.99
171	Familial hypertrophic cardiomyopathy	Enrichment	MYH7, MYL2, MYL3	1.94
172	Vitamin d hydroxylation-deficient rickets, type 1b	Enrichment	PDE3B	1.91
173	Birk-barel syndrome	Enrichment	KCNK9	1.91
174	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	1.91
175	Epilepsy, nocturnal frontal lobe, 5	Enrichment	KCNT1	1.91
176	Developmental and epileptic encephalopathy 15	Enrichment	KCNT1	1.91
177	Facial dysmorphism, hypertrichosis, epilepsy, intellectual/developmental delay, and gingival overgrowth syndrome	Enrichment	KCNK4	1.91
178	Ocular melanoma	Enrichment	PLCB4	1.91
179	Epilepsy, progressive myoclonic, 3, with or without intracellular inclusions	Enrichment	KCTD7	1.91
180	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	1.91
181	Malignant migrating partial seizures of infancy	Enrichment	KCNT1	1.91
182	Cerebral visual impairment	Enrichment	GNB1	1.91
183	Dravet syndrome	Enrichment	GABRA1, GABRG2	1.91
184	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	1.84
185	Pyloric stenosis, infantile hypertrophic, 1	Enrichment	NOS1	1.84
186	Contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a	Enrichment	MYH3	1.84
187	Achromatopsia 2	Enrichment	CNGA3	1.84
188	Baraitser-winter syndrome 1	Enrichment	ACTB	1.84
189	Deafness, autosomal recessive 2	Enrichment	MYO7A	1.84
190	Deafness, autosomal dominant 17	Enrichment	MYH9	1.84
191	Deafness, autosomal dominant 48	Enrichment	MYO1A	1.84
192	Cardiomyopathy, familial hypertrophic, 8	Enrichment	MYL3	1.84
193	Congenital myopathy 2a, typical, autosomal dominant	Enrichment	ACTA1	1.84
194	Deafness, autosomal dominant 22	Enrichment	MYO6	1.84
195	Dyskinesia with orofacial involvement, autosomal dominant	Enrichment	ADCY5	1.84
196	Myopathy, scapulohumeroperoneal	Enrichment	ACTA1	1.84
197	Cardiomyopathy, dilated, 1ee	Enrichment	MYH6	1.84
198	Sick sinus syndrome 3	Enrichment	MYH6	1.84
199	Griscelli syndrome, type 1	Enrichment	MYO5A	1.84
200	Aortic aneurysm, familial thoracic 8	Enrichment	PRKG1	1.84
201	Elejalde neuroectodermal melanolysosomal syndrome	Enrichment	MYO5A	1.84
202	Megacystis-microcolon-intestinal hypoperistalsis syndrome 5	Enrichment	ACTG2	1.84
203	Spondylometaphyseal dysplasia, pagnamenta type	Enrichment	PRKG2	1.84
204	Neurodevelopmental disorder with hyperkinetic movements and dyskinesia	Enrichment	ADCY5	1.84
205	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	1.84
206	Deafness, autosomal dominant 4a	Enrichment	MYH14	1.84
207	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	1.84
208	Deafness, autosomal recessive 37	Enrichment	MYO6	1.84
209	Night blindness, congenital stationary, type1i	Enrichment	GUCY2D	1.84
210	Diarrhea 15, congenital	Enrichment	MYO1A	1.84
211	Atrial fibrillation, familial, 18	Enrichment	MYL4	1.84
212	Deafness, autosomal dominant 11	Enrichment	MYO7A	1.84
213	Dyskinesia with orofacial involvement, autosomal recessive	Enrichment	ADCY5	1.84
214	Deafness, autosomal recessive 30	Enrichment	MYO3A	1.84
215	Becker nevus syndrome	Enrichment	ACTB	1.84
216	Celiac disease 4	Enrichment	MYO9B	1.84
217	Dystonia-deafness syndrome 1	Enrichment	ACTB	1.84
218	Visceral neuropathy, familial, 3, autosomal dominant	Enrichment	ACTG2	1.84
219	Cardiomyopathy, familial hypertrophic, 14	Enrichment	MYH6	1.84
220	Congenital myopathy 2b, severe infantile, autosomal recessive	Enrichment	ACTA1	1.84
221	Moyamoya disease 6 with or without achalasia	Enrichment	GUCY1A1	1.84
222	Peripheral neuropathy, myopathy, hoarseness, and hearing loss	Enrichment	MYH14	1.84
223	Acrodysostosis 2 with or without hormone resistance	Enrichment	PDE4D	1.84
224	Autosomal dominant familial visceral neuropathy	Enrichment	ACTG2	1.84
225	Focal segmental glomerulosclerosis 6	Enrichment	MYO1E	1.84
226	Retinitis pigmentosa 45	Enrichment	CNGB1	1.84
227	Noonan syndrome-like disorder with loose anagen hair 2	Enrichment	PPP1CB	1.84
228	Congenital myopathy 2c, severe infantile, autosomal dominant	Enrichment	ACTA1	1.84
229	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	1.84
230	Deafness, autosomal dominant 90	Enrichment	MYO3A	1.84
231	Myasthenic syndrome, congenital, 24, presynaptic	Enrichment	MYO9A	1.84
232	Congenital myopathy 14	Enrichment	MYL1	1.84
233	Moyamoya disease with early-onset achalasia	Enrichment	GUCY1A1	1.84
234	Baraitser-winter syndrome	Enrichment	ACTB	1.84
235	Usher syndrome type 1b	Enrichment	MYO7A	1.84
236	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	1.84
237	Klippel-feil syndrome	Enrichment	MYO18B	1.84
238	Autosomal dominant nonsyndromic hearing loss 17	Enrichment	MYH9	1.84
239	Idiopathic hypercalciuria	Enrichment	ADCY10	1.84
240	Progressive sensorineural hearing loss-hypertrophic cardiomyopathy syndrome	Enrichment	MYO6	1.84
241	Zebra body myopathy	Enrichment	ACTA1	1.84
242	Congenital smooth muscle hamartoma	Enrichment	ACTB	1.84
243	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	1.84
244	Autosomal dominant nonsyndromic hearing loss 22	Enrichment	MYO6	1.84
245	Actin-accumulation myopathy	Enrichment	ACTA1	1.84
246	Myopathic intestinal pseudoobstruction	Enrichment	ACTG2	1.84
247	Actg2 visceral myopathy	Enrichment	ACTG2	1.84
248	Epilepsy, myoclonic juvenile	Enrichment	GABRA1, GABRD	1.83
249	Aortic aneurysm, familial thoracic 1	Enrichment	MYH11, MYLK	1.78
250	Sick sinus syndrome 2	Enrichment	HCN4	1.76
251	Osteopetrosis and infantile neuroaxonal dystrophy	Enrichment	PLA2G6	1.76
252	Congenital disorder of glycosylation, type iid	Enrichment	B4GALT1	1.76
253	Febrile seizures, familial, 8	Enrichment	GABRG2	1.76
254	Epilepsy, idiopathic generalized 13	Enrichment	GABRA1	1.76
255	Ehlers-danlos syndrome, spondylodysplastic type, 1	Enrichment	B4GALT7	1.76
256	Cardiac valvular dysplasia 1	Enrichment	PLD1	1.76
257	Microcephaly and chorioretinopathy, autosomal recessive, 2	Enrichment	PLK4	1.76
258	Fleck retina, familial benign	Enrichment	PLA2G5	1.76
259	Neurodevelopmental disorder with involuntary movements	Enrichment	GNAO1	1.76
260	Epilepsy, idiopathic generalized 17	Enrichment	HCN2	1.76
261	Epilepsy, idiopathic generalized 18	Enrichment	HCN4	1.76
262	Neurodegeneration with brain iron accumulation 2a	Enrichment	PLA2G6	1.76
263	Developmental and epileptic encephalopathy 74	Enrichment	GABRG2	1.76
264	Developmental and epileptic encephalopathy 79	Enrichment	GABRA5	1.76
265	Immunodeficiency 110 with lymphoproliferation	Enrichment	STK4	1.76
266	Epilepsy, x-linked 2, with or without impaired intellectual development and dysmorphic features	Enrichment	GABRA3	1.76
267	Intellectual developmental disorder, x-linked 114	Enrichment	SRPK3	1.76
268	Epilepsy, idiopathic generalized 10	Enrichment	GABRD	1.76
269	Familial febrile seizures 2	Enrichment	HCN2	1.76
270	Autism 16	Enrichment	SLC9A9	1.76
271	Developmental and epileptic encephalopathy 17	Enrichment	GNAO1	1.76
272	Developmental and epileptic encephalopathy 19	Enrichment	GABRA1	1.76
273	Parkinson disease 14, autosomal recessive	Enrichment	PLA2G6	1.76
274	Neurodegeneration with brain iron accumulation 2b	Enrichment	PLA2G6	1.76
275	Cytosolic phospholipase-a2 alpha deficiency associated bleeding disorder	Enrichment	PLA2G4A	1.76
276	Spermatogenic failure 93	Enrichment	STK33	1.76
277	Nasopharyngeal carcinoma 3	Enrichment	MST1R	1.76
278	Developmental and epileptic encephalopathy 24	Enrichment	HCN1	1.76
279	Microcephaly and chorioretinopathy 2	Enrichment	PLK4	1.76
280	Epilepsy, childhood absence 5	Enrichment	GABRB3	1.76
281	Cdkl5 deficiency disorder	Enrichment	CDKL5	1.76
282	Platelet-activating factor acetylhydrolase deficiency	Enrichment	PLA2G7	1.76
283	Developmental and epileptic encephalopathy 92	Enrichment	GABRB2	1.76
284	Gastrointestinal ulceration, recurrent, with dysfunctional platelets	Enrichment	PLA2G4A	1.76
285	Developmental and epileptic encephalopathy 43	Enrichment	GABRB3	1.76
286	Developmental and epileptic encephalopathy 45	Enrichment	GABRB1	1.76
287	Combined low ldl and fibrinogen	Enrichment	B4GALT1	1.76
288	Generalized epilepsy with febrile seizures plus, type 10	Enrichment	HCN1	1.76
289	Ciliary dyskinesia, primary, 46	Enrichment	STK36	1.76
290	Spondylodysplastic ehlers-danlos syndrome	Enrichment	B4GALT7	1.76
291	Cryptogenic multifocal ulcerous stenosing enteritis	Enrichment	PLA2G4A	1.76
292	Gnao1-related disorder	Enrichment	GNAO1	1.76
293	Intestinal polyposis syndrome	Enrichment	STK11	1.76
294	Familial benign flecked retina	Enrichment	PLA2G5	1.76
295	Amelogenesis imperfecta, type ig	Enrichment	PRKAR1A	1.76
296	Cutis marmorata telangiectatica congenita	Enrichment	GNA11	1.76
297	Timothy syndrome	Enrichment	CACNA1C	1.76
298	Night blindness, congenital stationary, type 2a	Enrichment	CACNA1F	1.76
299	Alternating hemiplegia of childhood 1	Enrichment	CACNA1A	1.76
300	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	1.76
301	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.76
302	Angioma, tufted	Enrichment	GNA14	1.76
303	Spermatogenic failure 17	Enrichment	PLCZ1	1.76
304	Long qt syndrome 14	Enrichment	CALM1	1.76
305	Long qt syndrome 8	Enrichment	CACNA1C	1.76
306	Marbach-schaaf neurodevelopmental syndrome	Enrichment	PRKAR1B	1.76
307	Usher syndrome, type iv	Enrichment	PRKAR1A	1.76
308	Autosomal dominant hypocalcemia	Enrichment	GNA11	1.76
309	Body mass index quantitative trait locus 19	Enrichment	ADCY3	1.76
310	Fibrolamellar carcinoma	Enrichment	PRKACA	1.76
311	Ciliary dyskinesia, primary, 18	Enrichment	PRKAR1B	1.76
312	Congenital disorder of glycosylation, type iw, autosomal dominant	Enrichment	CACNA1D	1.76
313	Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements	Enrichment	CACNA1B	1.76
314	Isolated primary pigmented nodular adrenocortical disease	Enrichment	PRKAR1A	1.76
315	Progressive bulbar palsy	Enrichment	CACNA1A	1.76
316	Phakomatosis cesioflammea	Enrichment	GNA11	1.76
317	Vitamin d hydroxylation-deficient rickets, type 1a	Enrichment	PDE3B	1.73
318	Epilepsy, nocturnal frontal lobe, 1	Enrichment	KCNT1	1.73
319	Ciliary dyskinesia, primary, 28	Enrichment	KCNT1	1.73
320	Gingival overgrowth	Enrichment	KCNK4	1.73
321	Myopia	Enrichment	CACNA1F, MYH11	1.72
322	Myopathy	Enrichment	ACTA1, MYH2, MYH7	1.71
323	Pseudohypoparathyroidism, type ia	Enrichment	GNAS	1.69
324	Pituitary adenoma 4, acth-secreting	Enrichment	GNAI2	1.69
325	Pulmonic stenosis	Enrichment	BRAF	1.69
326	Pseudopseudohypoparathyroidism	Enrichment	GNAS	1.69
327	Pseudohypoparathyroidism	Enrichment	GNAS	1.69
328	Hypopituitarism	Enrichment	GNAI2	1.69
329	Intellectual developmental disorder with or without epilepsy or cerebellar ataxia	Enrichment	RORA	1.69
330	Acth-independent macronodular adrenal hyperplasia	Enrichment	GNAS	1.69
331	Tafro syndrome	Enrichment	MAP2K2	1.69
332	Chromosome 1p36 deletion syndrome	Enrichment	GABRD, PRKCZ	1.68
333	Distal arthrogryposis	Enrichment	ACTA1, MYH3, MYL11	1.66
334	Strabismus	Enrichment	CACNA1A, GNB1	1.63
335	Hereditary retinal dystrophy	Enrichment	CACNA1F, CACNA2D4, CNGA1, CNGA3, CNGB1, CNGB3, GUCY2D, KCNV2, MYO7A	1.62
336	Fundus dystrophy	Enrichment	CACNA1F, CACNA2D4, CNGA1, CNGA3, CNGB1, CNGB3, GUCY2D, KCNV2, MYO7A	1.62
337	Hypertension, essential	Enrichment	GNB3, NOS3	1.62
338	Cardiomyopathy, dilated, 1e	Enrichment	MYH7, MYL2	1.62
339	Congenital nervous system abnormality	Enrichment	CACNA1A, CAMK2B, GNB5, KCNV2	1.62
340	Nervous system disease	Enrichment	CACNA1A, CAMK2B, GNB5, KCNV2	1.62
341	Developmental and epileptic encephalopathy	Enrichment	CDKL5, GNAO1, HCN1	1.61
342	Developmental and epileptic encephalopathy 12	Enrichment	PLCB1	1.61
343	Hereditary ataxia	Enrichment	PRKCG	1.61
344	Van der woude syndrome 1	Enrichment	CACNA1E	1.58
345	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	GNA11	1.58
346	Nephrotic syndrome, type 3	Enrichment	PLCE1	1.58
347	Thyrotoxic periodic paralysis	Enrichment	CACNA1S	1.58
348	Hereditary episodic ataxia	Enrichment	CACNA1A	1.58
349	Benign epilepsy with centrotemporal spikes	Enrichment	KCNT1, PLCB1	1.58
350	Neuromuscular disease	Enrichment	ACTA1, MYH7	1.57
351	Dilated cardiomyopathy	Enrichment	ACTA1, MYH6, MYH7, MYL2	1.56
352	Spinocerebellar ataxia 29	Enrichment	ITPR1	1.55
353	Aortic aneurysm, familial thoracic 4	Enrichment	MYH11	1.55
354	Hypercalciuria, absorptive, 2	Enrichment	ADCY10	1.55
355	Arthrogryposis, distal, type 2a	Enrichment	MYH3	1.55
356	Ebstein anomaly	Enrichment	MYH7	1.55
357	Cataract 35	Enrichment	MYH9	1.55
358	Deafness, autosomal dominant 30	Enrichment	MYO3A	1.55
359	Aortic aneurysm, familial thoracic 2	Enrichment	ACTA2	1.55
360	Griscelli syndrome, type 3	Enrichment	MYO5A	1.55
361	Arthrogryposis, distal, type 7	Enrichment	MYH8	1.55
362	Deafness, autosomal dominant 20	Enrichment	ACTG1	1.55
363	Smooth muscle dysfunction syndrome	Enrichment	ACTA2	1.55
364	Aortic aneurysm, familial thoracic 6	Enrichment	ACTA2	1.55
365	Baraitser-winter syndrome 2	Enrichment	ACTG1	1.55
366	Lethal congenital contracture syndrome 8	Enrichment	ADCY6	1.55
367	Duodenal atresia	Enrichment	GUCY2C	1.55
368	Chromosome 5q12 deletion syndrome	Enrichment	PDE4D	1.55
369	Epiphyseal chondrodysplasia, miura type	Enrichment	NPR2	1.55
370	Moyamoya disease 5	Enrichment	ACTA2	1.55
371	Arthrogryposis, distal, type 2b3	Enrichment	MYH3	1.55
372	Megacystis-microcolon-intestinal hypoperistalsis syndrome 2	Enrichment	MYH11	1.55
373	Genitourinary and/or brain malformation syndrome	Enrichment	PPP1R12A	1.55
374	Retinitis pigmentosa 49	Enrichment	CNGA1	1.55
375	Atrial septal defect 3	Enrichment	MYH6	1.55
376	Noonan syndrome-like disorder with loose anagen hair	Enrichment	PPP1CB	1.55
377	Acromesomelic dysplasia 4	Enrichment	PRKG2	1.55
378	Cardiomyopathy, familial hypertrophic, 10	Enrichment	MYL2	1.55
379	Acromesomelic dysplasia 1	Enrichment	NPR2	1.55
380	Diarrhea 6	Enrichment	GUCY2C	1.55
381	Hereditary inclusion body myopathy-joint contractures-ophthalmoplegia syndrome	Enrichment	MYH2	1.55
382	Pseudosarcomatous fibromatosis	Enrichment	MYH9	1.55
383	Visceral myopathy 2	Enrichment	MYH11	1.55
384	Myopathy, myofibrillar, 12, infantile-onset, with cardiomyopathy	Enrichment	MYL2	1.55
385	Klippel-feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism	Enrichment	MYO18B	1.55
386	Arthrogryposis, distal, type 1c	Enrichment	MYL11	1.55
387	Megacystis-microcolon-intestinal hypoperistalsis syndrome 4	Enrichment	MYL9	1.55
388	Congenital diarrhea 6	Enrichment	GUCY2C	1.55
389	Intestinal obstruction in the newborn due to guanylate cyclase 2c deficiency	Enrichment	GUCY2C	1.55
390	Klippel-feil anomaly-myopathy-facial dysmorphism syndrome	Enrichment	MYO18B	1.55
391	Childhood-onset autosomal recessive myopathy with external ophthalmoplegia	Enrichment	MYH2	1.55
392	Intestinal obstruction	Enrichment	ACTG2	1.55
393	Carney complex - trismus - pseudocamptodactyly syndrome	Enrichment	MYH8	1.55
394	Centralopathic epilepsy	Enrichment	KCNT1, PLCB1	1.54
395	Convulsions, familial infantile, with paroxysmal choreoathetosis	Enrichment	PDE2A	1.51
396	Mccune-albright syndrome	Enrichment	GNAS	1.51
397	Ataxia-telangiectasia	Enrichment	BRAF	1.51
398	Tethered spinal cord syndrome	Enrichment	BRAF	1.51
399	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	GNAS	1.51
400	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	KCTD3, PLA2G6	1.51
401	Sensorineural hearing loss	Enrichment	MYO15A, MYO3A, MYO7A	1.51
402	Epilepsy	Enrichment	GABRA1, GABRB3, KCNT1	1.49
403	Retinitis pigmentosa	Enrichment	CACNA1F, CACNA2D4, CNGA1, CNGB1, CNGB3, GUCY2D, MYO7A	1.48
404	Peutz-jeghers syndrome	Enrichment	STK11	1.46
405	Retinoschisis 1, x-linked, juvenile	Enrichment	CDKL5	1.46
406	Charcot-marie-tooth disease, demyelinating, type 4f	Enrichment	PLD3	1.46
407	Ehlers-danlos syndrome, spondylodysplastic type, 2	Enrichment	B4GALT7	1.46
408	Oocyte/zygote/embryo maturation arrest 3	Enrichment	ZP3	1.46
409	Spinocerebellar ataxia 46	Enrichment	PLD3	1.46
410	Spermatogenic failure 7	Enrichment	CATSPER1	1.46
411	Developmental and epileptic encephalopathy 78	Enrichment	GABRA2	1.46
412	Charcot-marie-tooth disease type 4f	Enrichment	PLD3	1.46
413	Retinoschisis	Enrichment	CDKL5	1.46
414	Infantile osteopetrosis with neuroaxonal dysplasia	Enrichment	PLA2G6	1.46
415	Bruxism	Enrichment	CDKL5	1.46
416	Body mass index quantitative trait locus 11	Enrichment	ADCY3, GNAS, MYH9	1.46
417	Migraine, familial hemiplegic, 1	Enrichment	CACNA1A	1.46
418	Spinocerebellar ataxia 6	Enrichment	CACNA1A	1.46
419	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	1.46
420	Aland island eye disease	Enrichment	CACNA1F	1.46
421	Developmental and epileptic encephalopathy 2	Enrichment	CACNA1A	1.46
422	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	1.46
423	Ventricular fibrillation, paroxysmal familial, 1	Enrichment	CACNA1C	1.46
424	Arrhythmogenic right ventricular dysplasia, familial, 10	Enrichment	PRKAR1A	1.46
425	Developmental and epileptic encephalopathy 42	Enrichment	CACNA1A	1.46
426	Cerebellar atrophy with seizures and variable developmental delay	Enrichment	CACNA2D2	1.46
427	Developmental and epileptic encephalopathy 52	Enrichment	CACNA1A	1.46
428	Malignant hyperthermia	Enrichment	CACNA1S	1.46
429	Episodic ataxia	Enrichment	CACNA1A	1.46
430	Familial or sporadic hemiplegic migraine	Enrichment	CACNA1A	1.46
431	Centronuclear myopathy	Enrichment	ACTA1, CACNA1S	1.45
432	Alcohol dependence	Enrichment	TAS2R16	1.44
433	Early infantile developmental and epileptic encephalopathy	Enrichment	CDKL5, GNAO1	1.42
434	Spastic ataxia	Enrichment	CACNA1G, CACNB4, ITPR1	1.40
435	Thyroid cancer, nonmedullary, 1	Enrichment	BRAF	1.39
436	Pseudohypoparathyroidism, type ib	Enrichment	GNAS	1.39
437	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.39
438	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.39
439	Achromatopsia 4	Enrichment	GNAI3	1.39
440	Congenital generalized lipodystrophy	Enrichment	FOS	1.39
441	Craniopharyngioma	Enrichment	BRAF	1.39
442	Newborn respiratory distress syndrome	Enrichment	BRAF	1.39
443	West syndrome	Enrichment	CDKL5, GNAO1, PLCB1	1.39
444	Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss	Enrichment	MYH9	1.37
445	Klippel-feil syndrome 1, autosomal dominant	Enrichment	MYO18B	1.37
446	Gillespie syndrome	Enrichment	ITPR1	1.37
447	Diarrhea 3, secretory sodium, congenital, with or without other congenital anomalies	Enrichment	GUCY2C	1.37
448	Deafness, autosomal recessive 3	Enrichment	MYO15A	1.37
449	Cardiomyopathy, dilated, 1c, with or without left ventricular noncompaction	Enrichment	MYH7B	1.37
450	Spondylocarpotarsal synostosis syndrome	Enrichment	MYH3	1.37
451	Aortic aneurysm, familial thoracic 7	Enrichment	MYLK	1.37
452	Epilepsy, familial focal, with variable foci 2	Enrichment	NPR2	1.37
453	Microcephaly, progressive, with seizures and cerebral and cerebellar atrophy	Enrichment	MYH15	1.37
454	Polr3-related leukodystrophy	Enrichment	GUCY2D	1.37
455	Qualitative or quantitative defects of beta-myosin heavy chain	Enrichment	MYH7	1.37
456	Idiopathic camptocormia	Enrichment	MYH7	1.37
457	Congenital diarrhea	Enrichment	MYO1A	1.37
458	Tricuspid valve insufficiency	Enrichment	MYH11	1.37
459	Hypomyelination neuropathy-arthrogryposis syndrome	Enrichment	ADCY6	1.37
460	Breast cancer	Enrichment	CACNA2D1, GNG3, JUN	1.37
461	Autosomal dominant sleep-related hypermotor epilepsy	Enrichment	KCNT1	1.37
462	Paroxysmal dystonia	Enrichment	PDE2A	1.37
463	Capillary malformations, congenital	Enrichment	GNA11	1.37
464	Episodic ataxia, type 2	Enrichment	CACNA1A	1.37
465	Heart conduction disease	Enrichment	CACNA1C	1.37
466	Amblyopia	Enrichment	CACNA1F	1.37
467	Cardiac arrest	Enrichment	CACNA2D1	1.37
468	Congenital short qt syndrome	Enrichment	CACNA2D1	1.37
469	Hypothyroidism	Enrichment	GNB1	1.31
470	Histiocytoid hemangioma	Enrichment	FOS	1.30
471	Succinic semialdehyde dehydrogenase deficiency	Enrichment	GPLD1	1.29
472	Late-onset retinal degeneration	Enrichment	PLA2G5	1.29
473	Multiple joint dislocations, short stature, and craniofacial dysmorphism with or without congenital heart defects	Enrichment	B4GALT7	1.29
474	Larsen-like syndrome b3gat3 type	Enrichment	B4GALT7	1.29
475	Testicular germ cell cancer	Enrichment	STK11	1.29
476	Brugada syndrome 8	Enrichment	HCN4	1.29
477	Microcephaly 17, primary, autosomal recessive	Enrichment	CIT	1.29
478	Testicular cancer	Enrichment	STK11	1.29
479	Apc-associated polyposis conditions	Enrichment	STK11	1.29
480	Hypokalemic periodic paralysis, type 1	Enrichment	CACNA1S	1.29
481	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	1.29
482	Adrenocortical carcinoma	Enrichment	PRKAR1A	1.29
483	Auditory neuropathy	Enrichment	CACNA1A, MYO7A	1.28
484	Inflammatory bowel disease 1	Enrichment	PRKCQ	1.26
485	Myopathy, distal, 1	Enrichment	MYH7	1.25
486	Chorea, benign hereditary	Enrichment	ADCY5	1.25
487	Klippel-feil syndrome 2, autosomal recessive	Enrichment	MYO18B	1.25
488	Nemaline myopathy 2	Enrichment	ACTA1	1.25
489	Congenital myopathy 7b, myosin storage, autosomal recessive	Enrichment	MYH7	1.25
490	Autoimmune lymphoproliferative syndrome	Enrichment	ACTA2	1.25
491	Congenital myopathy 7a, myosin storage, autosomal dominant	Enrichment	MYH7	1.25
492	Congenital myopathy 6 with ophthalmoplegia	Enrichment	MYH2	1.25
493	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.25
494	Aminoacylase 1 deficiency	Enrichment	ACTB	1.25
495	Meconium ileus	Enrichment	GUCY2C	1.25
496	Short stature with nonspecific skeletal abnormalities 1	Enrichment	NPR2	1.25
497	Contractures, pterygia, and spondylocarpotarsal fusion syndrome 1b	Enrichment	MYH3	1.25
498	Hyaline body myopathy	Enrichment	MYH7	1.25
499	Idiopathic achalasia	Enrichment	NOS1	1.25
500	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	MYH11	1.25
501	Mitral valve insufficiency	Enrichment	MYH11	1.25
502	Intermediate nemaline myopathy	Enrichment	ACTA1	1.25
503	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.25
504	Brugada syndrome 1	Enrichment	CACNA2D1	1.22
505	Stroke, ischemic	Enrichment	PRKCH	1.22
506	Progressive myoclonus epilepsy	Enrichment	KCTD7	1.22
507	Epilepsy, childhood absence 1	Enrichment	RORB	1.22
508	Wilms tumor 5	Enrichment	BRAF	1.22
509	Deafness, autosomal recessive	Enrichment	MYH9, MYO15A, MYO7A	1.21
510	Autosomal recessive nonsyndromic deafness	Enrichment	MYH9, MYO15A, MYO7A	1.20
511	Leukemia, acute lymphoblastic	Enrichment	GNB1	1.18
512	Myelodysplastic syndrome	Enrichment	GNB1	1.18
513	Heritable pulmonary arterial hypertension	Enrichment	KCNK3	1.18
514	Nicolaides-baraitser syndrome	Enrichment	CDKL5	1.17
515	Deafness-infertility syndrome	Enrichment	CATSPER2	1.17
516	Developmental and epileptic encephalopathy 4	Enrichment	CDKL5	1.17
517	Oocyte/zygote/embryo maturation arrest 1	Enrichment	ZP3	1.17
518	Autosomal dominant nocturnal frontal lobe epilepsy	Enrichment	GABRG2	1.17
519	Smarca2-related nicolaides-baraitser syndrome	Enrichment	CDKL5	1.17
520	Autosomal recessive chorioretinopathy-microcephaly syndrome	Enrichment	PLK4	1.17
521	Alternating hemiplegia of childhood	Enrichment	CACNA1A	1.17
522	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	1.17
523	Difference of sex development	Enrichment	CACNA1A	1.17
524	Stargardt disease 1	Enrichment	CNGB3, KCNV2	1.17
525	Alzheimer disease 2	Enrichment	NOS3	1.16
526	Choroidal dystrophy, central areolar, 1	Enrichment	GUCY2D	1.16
527	3-methylglutaconic aciduria, type iii	Enrichment	GUCY2D	1.16
528	Arthrogryposis, distal, type 2b1	Enrichment	MYH3	1.16
529	Deafness, autosomal recessive 9	Enrichment	MYO15A	1.16
530	Deafness, autosomal recessive 63	Enrichment	MYH9	1.16
531	Pre-eclampsia	Enrichment	NOS3	1.16
532	Congenital ptosis	Enrichment	MYH10	1.16
533	Macular degeneration	Enrichment	CNGA3	1.16
534	Otof-related hearing loss	Enrichment	MYO15A	1.16
535	Coloboma of choroid and retina	Enrichment	ACTG1	1.16
536	Severe congenital nemaline myopathy	Enrichment	ACTA1	1.16
537	Developmental and epileptic encephalopathy 1	Enrichment	CDKL5, GNAO1	1.16
538	Type 2 diabetes mellitus	Enrichment	MTNR1B, SLC2A4	1.16
539	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF	1.15
540	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1	1.15
541	Noonan syndrome 3	Enrichment	RAF1	1.15
542	Brachydactyly	Enrichment	GNAS	1.15
543	Gallbladder cancer	Enrichment	BRAF	1.15
544	Follicular thyroid carcinoma	Enrichment	BRAF	1.15
545	Nephrotic syndrome, type 1	Enrichment	PLCE1	1.12
546	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	CACNA1C	1.12
547	Pulmonary hypertension, primary, 1	Enrichment	KCNK3	1.11
548	Pulmonary disease, chronic obstructive	Enrichment	PDE3B	1.11
549	Spastic paraplegia 4, autosomal dominant	Enrichment	GNAS	1.10
550	Lymphoma, non-hodgkin, familial	Enrichment	BRAF	1.10
551	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	MYO6	1.08
552	Hemangioma, capillary infantile	Enrichment	MYH9	1.08
553	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	1.08
554	Inherited arrhythmogenic cardiomyopathy	Enrichment	MYH7	1.08
555	Typical nemaline myopathy	Enrichment	ACTA1	1.08
556	Myoclonic epilepsy of unverricht and lundborg	Enrichment	KCTD7	1.08
557	Variegate porphyria	Enrichment	B4GALT3	1.08
558	Familial adenomatous polyposis 1	Enrichment	STK11	1.08
559	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	STK11	1.08
560	Genetic steroid-resistant nephrotic syndrome	Enrichment	MYO1E, PLCE1	1.07
561	Neuronal ceroid lipofuscinosis	Enrichment	KCTD7	1.05
562	Left ventricular noncompaction	Enrichment	MYH7, MYH7B	1.05
563	Cardiomyopathy, familial hypertrophic, 4	Enrichment	BRAF	1.05
564	Arteriovenous malformation	Enrichment	MAP2K1	1.05
565	Ventricular septal defect	Enrichment	BRAF	1.05
566	Migraine with or without aura 1	Enrichment	CACNA1A	1.03
567	Meniere disease	Enrichment	MYO7A	1.02
568	Childhood-onset nemaline myopathy	Enrichment	ACTA1	1.02
569	Familial isolated restrictive cardiomyopathy	Enrichment	MYL2	1.02
570	Myopathy, x-linked, with excessive autophagy	Enrichment	MAP2K1	1.01
571	Melanoma	Enrichment	BRAF	1.01
572	Spondyloepiphyseal dysplasia with congenital joint dislocations	Enrichment	B4GALT7	1.00
573	Cleft palate, isolated	Enrichment	GNB1	1.00
574	Cardiac conduction defect	Enrichment	CACNA1C	1.00
575	Specific learning disability	Enrichment	MAPK1	0.97
576	Acute promyelocytic leukemia	Enrichment	PRKAR1A	0.97
577	Arthrogryposis, distal, type 1a	Enrichment	MYH3	0.96
578	Leber congenital amaurosis 1	Enrichment	GUCY2D	0.96
579	Myocarditis	Enrichment	MYH7	0.96
580	Hypoplastic left heart syndrome	Enrichment	MYH6	0.96
581	Rett syndrome	Enrichment	CDKL5	0.94
582	Focal epilepsy	Enrichment	CDKL5	0.94
583	Lip and oral cavity carcinoma	Enrichment	BRAF	0.93
584	Familial isolated arrhythmogenic right ventricular dysplasia	Enrichment	MYH7	0.91
585	Nephrotic syndrome	Enrichment	MYO1E, PLCE1	0.90
586	Attention deficit-hyperactivity disorder	Enrichment	GNB5	0.89
587	Spermatogenic failure 5	Enrichment	AURKC	0.88
588	Rett syndrome, congenital variant	Enrichment	CDKL5	0.88
589	Cat eye syndrome	Enrichment	ACTG1	0.87
590	Microcephaly	Enrichment	CAMK2B, GNB1, MAPK1	0.87
591	Lung cancer susceptibility 3	Enrichment	BRAF	0.87
592	Complex neurodevelopmental disorder	Enrichment	CACNA1C, GNB2, RORA	0.86
593	Sudden infant death syndrome	Enrichment	CALM2	0.86
594	Wilms tumor 1	Enrichment	BRAF	0.84
595	Usher syndrome type 2	Enrichment	MYO7A	0.83
596	Presynaptic congenital myasthenic syndromes	Enrichment	MYO9A	0.83
597	Restrictive cardiomyopathy	Enrichment	MYH7	0.80
598	Congenital long qt syndrome	Enrichment	ITPR3	0.80
599	Neurodegeneration with brain iron accumulation	Enrichment	PLA2G6	0.79
600	Familial colorectal cancer	Enrichment	PLA2G2A	0.79
601	Focal segmental glomerulosclerosis	Enrichment	PLCE1	0.79
602	Melanoma, cutaneous malignant 1	Enrichment	BRAF	0.79
603	Dandy-walker syndrome	Enrichment	BRAF	0.79
604	Heart, malformation of	Enrichment	MAPK1	0.77
605	Normosmic congenital hypogonadotropic hypogonadism	Enrichment	GNRH1	0.77
606	Microphthalmia/coloboma 12	Enrichment	MYH10	0.77
607	Familial isolated dilated cardiomyopathy	Enrichment	MYH6, MYH7	0.76
608	Movement disease	Enrichment	GNAO1	0.76
609	Ciliopathy	Enrichment	NEK4	0.76
610	Arteriovenous malformations of the brain	Enrichment	BRAF	0.75
611	Diffuse large b-cell lymphoma	Enrichment	BRAF	0.75
612	Multiple sclerosis	Enrichment	ITPR1	0.74
613	Heart disease	Enrichment	MYL2	0.74
614	Colorectal cancer	Enrichment	AURKA, PLA2G2A, SLC9A9	0.71
615	Coloboma of macula	Enrichment	MYH10	0.71
616	Usher syndrome, type i	Enrichment	MYO7A	0.71
617	Anterior segment dysgenesis	Enrichment	ITPR1	0.71
618	Stereotypic movement disorder	Enrichment	CDKL5	0.69
619	Nk-cell enteropathy	Enrichment	AURKB	0.69
620	Wolff-parkinson-white syndrome	Enrichment	MYH7	0.69
621	Hypertension	Enrichment	MYH9	0.69
622	Alzheimer disease, familial, 1	Enrichment	NOS3	0.66
623	Seckel syndrome	Enrichment	PLK4	0.66
624	Patent foramen ovale	Enrichment	MYH6	0.64
625	Rare genetic intellectual disability	Enrichment	GNAO1	0.64
626	Male infertility with spermatogenesis disorder	Enrichment	AURKC	0.64
627	Craniosynostosis	Enrichment	NPR2	0.60
628	Myeloma, multiple	Enrichment	AURKA, MST1R	0.59
629	Differentiated thyroid carcinoma	Enrichment	BRAF	0.58
630	Lissencephaly	Enrichment	ACTG1	0.58
631	Charcot-marie-tooth disease type 4	Enrichment	PLD3	0.57
632	Myocardial infarction	Enrichment	GUCY1A1	0.57
633	Lung cancer	Enrichment	BRAF	0.55
634	Familial atrial fibrillation	Enrichment	MYL4	0.53
635	Autism spectrum disorder	Enrichment	GNB1, MAP2K1	0.51
636	Hydrops fetalis, nonimmune	Enrichment	ACTA1	0.50
637	Non-syndromic male infertility due to sperm motility disorder	Enrichment	CATSPER1	0.48
638	Pancreatic cancer	Enrichment	STK11	0.45
639	Non-immune hydrops fetalis	Enrichment	ACTA1	0.44
640	Connective tissue disease	Enrichment	ACTA2	0.43
641	Usher syndrome	Enrichment	MYO7A	0.42
642	Primary ciliary dyskinesia	Enrichment	PRKAR1B, STK36	0.42
643	Cakut	Enrichment	ACTG1	0.41
644	Leber plus disease	Enrichment	CNGB3, GUCY2D	0.40
645	Fetal akinesia deformation sequence 1	Enrichment	ACTA1	0.38
646	Primary autosomal recessive microcephaly	Enrichment	CIT	0.37
647	Severe combined immunodeficiency	Enrichment	STK4	0.36
648	Thrombocytopenia	Enrichment	MYH9	0.30
649	Charcot-marie-tooth disease	Enrichment	PLD3	0.29
650	Autism	Enrichment	CAMK2G	0.28
651	Hypertelorism	Enrichment	MYH10	0.28
652	Gastric cancer	Enrichment	STK11	0.28
653	Hereditary breast ovarian cancer syndrome	Enrichment	MYO7A	0.26
654	Primary ovarian insufficiency	Enrichment	NOS3	0.24
655	Schizophrenia	Enrichment	GABRB2	0.19
656	Inherited cancer-predisposing syndrome	Enrichment	PRKAR1A, STK11	0.17

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Sweet Taste Signaling

Pathway Network for Sweet Taste Signaling

Pathway network for the Sweet Taste Signaling SuperPath

Member Pathways for Sweet Taste Signaling

Pathways in the Sweet Taste Signaling SuperPath

Gene overlap in member pathways for Sweet Taste Signaling SuperPath

Associated Genes for Sweet Taste Signaling

Associated Disorders for Sweet Taste Signaling

Disorders associated with Sweet Taste Signaling SuperPath

STRING Interaction Network for Sweet Taste Signaling

Sources for Sweet Taste Signaling