Synthesis of PC

No Pathway Network information available for Synthesis of PC

Pathways in the Synthesis of PC SuperPath

#	Name	Source	Genes
1	Synthesis of PC	Reactome	ABHD3 ACHE BCHE CEPT1 CHAT CHKA CHKB CHPT1 CSNK2A1 CSNK2A2 CSNK2B LPCAT1 LPIN1 LPIN2 LPIN3 MFSD2A PCTP PCYT1A PCYT1B PEMT PHOSPHO1 SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC44A5 STARD10 STARD7 (see all 28) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CEPT1	Choline/Ethanolamine Phosphotransferase 1	Protein Coding	1
2	PEMT	Phosphatidylethanolamine N-Methyltransferase	Protein Coding	1
3	STARD10	StAR Related Lipid Transfer Domain Containing 10	Protein Coding	1
4	CHAT	Choline O-Acetyltransferase	Protein Coding	1
5	CHKA	Choline Kinase Alpha	Protein Coding	1
6	CHKB	Choline Kinase Beta	Protein Coding	1
7	SLC44A3	Solute Carrier Family 44 Member 3	Protein Coding	1
8	CSNK2A1	Casein Kinase 2 Alpha 1	Protein Coding	1
9	CSNK2A2	Casein Kinase 2 Alpha 2	Protein Coding	1
10	CSNK2B	Casein Kinase 2 Beta	Protein Coding	1
11	PHOSPHO1	Phosphoethanolamine/Phosphocholine Phosphatase 1	Protein Coding	1
12	ABHD3	Abhydrolase Domain Containing 3, Phospholipase	Protein Coding	1
13	SLC44A5	Solute Carrier Family 44 Member 5	Protein Coding	1
14	LPIN1	Lipin 1	Protein Coding	1
15	SLC44A1	Solute Carrier Family 44 Member 1	Protein Coding	1
16	ACHE	Acetylcholinesterase (Yt Blood Group)	Protein Coding	1
17	PCYT1A	Phosphate Cytidylyltransferase 1A, Choline	Protein Coding	1
18	STARD7	StAR Related Lipid Transfer Domain Containing 7	Protein Coding	1
19	CHPT1	Choline Phosphotransferase 1	Protein Coding	1
20	SLC44A2	Solute Carrier Family 44 Member 2 (CTL2 Blood Group)	Protein Coding	1
21	PCTP	Phosphatidylcholine Transfer Protein	Protein Coding	1
22	BCHE	Butyrylcholinesterase	Protein Coding	1
23	LPIN3	Lipin 3	Protein Coding	1
24	LPCAT1	Lysophosphatidylcholine Acyltransferase 1	Protein Coding	1
25	SLC44A4	Solute Carrier Family 44 Member 4	Protein Coding	1
26	MFSD2A	MFSD2 Lysolipid Transporter A, Lysophospholipid	Protein Coding	1
27	PCYT1B	Phosphate Cytidylyltransferase 1B, Choline	Protein Coding	1
28	LPIN2	Lipin 2	Protein Coding	1

Disorders associated with Synthesis of PC SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Apnea, central sleep	Enrichment	CHAT	2.69
2	Epilepsy, familial adult myoclonic, 2	Enrichment	STARD7	2.69
3	Yt blood group antigen	Enrichment	ACHE	2.69
4	Neurodevelopmental disorder with microcephaly, movement abnormalities, and seizures	Enrichment	CHKA	2.69
5	Proximal myopathy with focal depletion of mitochondria	Enrichment	CHKB	2.69
6	Majeed syndrome	Enrichment	LPIN2	2.69
7	Neurodevelopmental disorder with progressive microcephaly, spasticity, and brain imaging abnormalities	Enrichment	MFSD2A	2.69
8	Butyrylcholinesterase deficiency	Enrichment	BCHE	2.69
9	Okur-chung neurodevelopmental syndrome	Enrichment	CSNK2A1	2.69
10	Neurodegeneration, childhood-onset, with ataxia, tremor, optic atrophy, and cognitive decline	Enrichment	SLC44A1	2.69
11	Deafness, autosomal dominant 72	Enrichment	SLC44A4	2.69
12	Aspiration pneumonia	Enrichment	CHAT	2.69
13	Craniodigital syndrome and intellectual disability syndrome	Enrichment	CSNK2B	2.69
14	Spondylometaphyseal dysplasia with cone-rod dystrophy	Enrichment	PCYT1A	2.38
15	Poirier-bienvenu neurodevelopmental syndrome	Enrichment	CSNK2B	2.38
16	Myasthenic syndrome, congenital, 21, presynaptic	Enrichment	CHAT	2.38
17	Lipodystrophy, congenital generalized, type 5	Enrichment	PCYT1A	2.38
18	Prognathism, mandibular	Enrichment	CSNK2B	2.21
19	Myasthenic syndrome, congenital, 6, presynaptic	Enrichment	CHAT	2.21
20	Myoglobinuria, acute recurrent, autosomal recessive	Enrichment	LPIN1	2.21
21	Bronchopulmonary dysplasia	Enrichment	CHAT	2.21
22	Muscular dystrophy, congenital, megaconial type	Enrichment	CHKB	2.08
23	Enophthalmos	Enrichment	CSNK2B	2.08
24	Syndactyly	Enrichment	CSNK2B	2.08
25	Hereditary recurrent myoglobinuria	Enrichment	LPIN1	2.08
26	Gastroesophageal reflux	Enrichment	CHAT	1.79
27	Cryptorchidism	Enrichment	MFSD2A	1.79
28	Cryptorchidism, unilateral or bilateral	Enrichment	MFSD2A	1.73
29	Myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency	Enrichment	CHAT	1.69
30	Autism spectrum disorder	Enrichment	CSNK2A1, CSNK2B	1.68
31	Presynaptic congenital myasthenic syndromes	Enrichment	CHAT	1.65
32	Lactic acidosis	Enrichment	CHAT	1.61
33	Microcephaly	Enrichment	CHKA, MFSD2A	1.58
34	Congenital myasthenic syndrome	Enrichment	CHAT	1.54
35	Autoinflammatory disease	Enrichment	LPIN2	1.31
36	Muscular dystrophy	Enrichment	CHKB	1.31
37	Primary autosomal recessive microcephaly	Enrichment	MFSD2A	1.19
38	Autosomal dominant non-syndromic intellectual disability	Enrichment	CSNK2B	1.01
39	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	SLC44A4	0.99
40	Autosomal recessive non-syndromic intellectual disability	Enrichment	CHKA	0.95
41	Leber plus disease	Enrichment	PCYT1A	0.75
42	Complex neurodevelopmental disorder	Enrichment	CSNK2A1	0.64

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Synthesis of PC

Member Pathways for Synthesis of PC

Pathways in the Synthesis of PC SuperPath

Associated Genes for Synthesis of PC

Associated Disorders for Synthesis of PC

Disorders associated with Synthesis of PC SuperPath

STRING Interaction Network for Synthesis of PC

Sources for Synthesis of PC