T cell modulation in pancreatic cancer

No Pathway Network information available for T cell modulation in pancreatic cancer

Pathways in the T cell modulation in pancreatic cancer SuperPath

#	Name	Source	Genes
1	T cell modulation in pancreatic cancer	WikiPathways	ARG1 B2M CCL17 CCL22 CD226 CD274 CD276 CD28 CD40 CD40LG CD80 CD86 CTLA4 CXCL12 ENTPD1 FAP FAS FASLG HAVCR2 HLA-A ICOS IDO1 IL10 IL6 LGALS1 LGALS3 LGALS9 NT5E PDCD1 PDCD1LG2 PGF PVR TGFB2 TGFB3 TIGIT TNFRSF4 TNFRSF9 TNFSF4 TNFSF9 VEGFA VEGFB VEGFC VEGFD VSIR VTCN1 (see all 45) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	VTCN1	V-Set Domain Containing T Cell Activation Inhibitor 1	Protein Coding	1
2	CD276	CD276 Molecule	Protein Coding	1
3	CCL22	C-C Motif Chemokine Ligand 22	Protein Coding	1
4	PDCD1LG2	Programmed Cell Death 1 Ligand 2	Protein Coding	1
5	FAP	Fibroblast Activation Protein Alpha	Protein Coding	1
6	VSIR	V-Set Immunoregulatory Receptor	Protein Coding	1
7	TIGIT	T Cell Immunoreceptor With Ig And ITIM Domains	Protein Coding	1
8	CCL17	C-C Motif Chemokine Ligand 17	Protein Coding	1
9	LGALS1	Galectin 1	Protein Coding	1
10	CD40	CD40 Molecule	Protein Coding	1
11	CD274	CD274 Molecule	Protein Coding	1
12	ICOS	Inducible T Cell Costimulator	Protein Coding	1
13	TNFRSF4	TNF Receptor Superfamily Member 4	Protein Coding	1
14	TNFSF9	TNF Superfamily Member 9	Protein Coding	1
15	TNFSF4	TNF Superfamily Member 4	Protein Coding	1
16	TNFRSF9	TNF Receptor Superfamily Member 9	Protein Coding	1
17	IL10	Interleukin 10	Protein Coding	1
18	LGALS9	Galectin 9	Protein Coding	1
19	HAVCR2	Hepatitis A Virus Cellular Receptor 2	Protein Coding	1
20	CD226	CD226 Molecule	Protein Coding	1
21	CD40LG	CD40 Ligand	Protein Coding	1
22	CD86	CD86 Molecule	Protein Coding	1
23	CD80	CD80 Molecule	Protein Coding	1
24	PDCD1	Programmed Cell Death 1	Protein Coding	1
25	CTLA4	Cytotoxic T-Lymphocyte Associated Protein 4	Protein Coding	1
26	LGALS3	Galectin 3	Protein Coding	1
27	HLA-A	Major Histocompatibility Complex, Class I, A	Protein Coding	1
28	B2M	Beta-2-Microglobulin	Protein Coding	1
29	CD28	CD28 Molecule	Protein Coding	1
30	IL6	Interleukin 6	Protein Coding	1
31	FAS	Fas Cell Surface Death Receptor	Protein Coding	1
32	FASLG	Fas Ligand	Protein Coding	1
33	VEGFC	Vascular Endothelial Growth Factor C	Protein Coding	1
34	VEGFD	Vascular Endothelial Growth Factor D	Protein Coding	1
35	PGF	Placental Growth Factor	Protein Coding	1
36	ARG1	Arginase 1	Protein Coding	1
37	IDO1	Indoleamine 2,3-Dioxygenase 1	Protein Coding	1
38	NT5E	5''-Nucleotidase Ecto	Protein Coding	1
39	ENTPD1	Ectonucleoside Triphosphate Diphosphohydrolase 1	Protein Coding	1
40	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	1
41	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	1
42	PVR	PVR Cell Adhesion Molecule	Protein Coding	1
43	CXCL12	C-X-C Motif Chemokine Ligand 12	Protein Coding	1
44	VEGFB	Vascular Endothelial Growth Factor B	Protein Coding	1
45	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1

Disorders associated with T cell modulation in pancreatic cancer SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Systemic lupus erythematosus	Enrichment	CTLA4, IL10, PDCD1, TNFSF4	5.10
2	Loeys-dietz syndrome 4	Enrichment	TGFB2, TGFB3	4.97
3	Mycosis fungoides	Enrichment	CD28, CTLA4	4.49
4	Saczary syndrome	Enrichment	CD28, CTLA4	4.49
5	Autoimmune lymphoproliferative syndrome	Enrichment	FAS, FASLG	4.19
6	Immunodeficiency, common variable, 1	Enrichment	CTLA4, ICOS	4.19
7	Loeys-dietz syndrome	Enrichment	TGFB2, TGFB3	3.42
8	Human immunodeficiency virus type 1	Enrichment	CXCL12, IL10	2.80
9	Behcet syndrome	Enrichment	FAS, IL10	2.75
10	Calcification of joints and arteries	Enrichment	NT5E	2.48
11	Celiac disease 3	Enrichment	CTLA4	2.48
12	Immunodeficiency 16	Enrichment	TNFRSF4	2.48
13	Immunodeficiency 43	Enrichment	B2M	2.48
14	Immunodeficiency with hyper-igm, type 1	Enrichment	CD40LG	2.48
15	Autoimmune disease, multisystem, infantile-onset, 4	Enrichment	PDCD1	2.48
16	Hereditary lymphedema id	Enrichment	VEGFC	2.48
17	Graft-versus-host disease	Enrichment	IL10	2.48
18	Type 1 diabetes mellitus 12	Enrichment	CTLA4	2.48
19	Lymphatic malformation 4	Enrichment	VEGFC	2.48
20	Dialysis-related amyloidosis	Enrichment	B2M	2.48
21	Microvascular complications of diabetes 1	Enrichment	VEGFA	2.48
22	Camurati-engelmann disease 2	Enrichment	TGFB2	2.48
23	Systemic lupus erythematosus 2	Enrichment	PDCD1	2.48
24	Immunodeficiency with hyper-igm, type 3	Enrichment	CD40	2.48
25	Birdshot chorioretinopathy	Enrichment	HLA-A	2.48
26	Immunodeficiency 123 with hpv-related verrucosis	Enrichment	CD28	2.48
27	Loeys-dietz syndrome 5	Enrichment	TGFB3	2.48
28	T-cell lymphoma, subcutaneous panniculitis-like	Enrichment	HAVCR2	2.48
29	Amyloidosis, hereditary systemic 6	Enrichment	B2M	2.48
30	Immunodeficiency 109 with lymphoproliferation	Enrichment	TNFRSF9	2.48
31	Autoimmune disease, multisystem, infantile-onset, 5	Enrichment	CD274	2.48
32	Cd40 ligand deficiency	Enrichment	CD40LG	2.48
33	Congenital primary lymphedema of gordon	Enrichment	VEGFC	2.48
34	Lung cancer	Enrichment	FAS, FASLG	2.30
35	Hashimoto thyroiditis	Enrichment	CTLA4	2.18
36	Argininemia	Enrichment	ARG1	2.18
37	Severe cutaneous adverse reaction	Enrichment	HLA-A	2.18
38	Spastic paraplegia 64, autosomal recessive	Enrichment	ENTPD1	2.18
39	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	TGFB2, TGFB3	2.03
40	Immunodeficiency 98 with autoinflammation, x-linked	Enrichment	FASLG	2.00
41	Immune dysregulation with autoimmunity, immunodeficiency, and lymphoproliferation	Enrichment	CTLA4	2.00
42	Asparagine synthetase deficiency	Enrichment	CTLA4	2.00
43	Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome	Enrichment	CTLA4	2.00
44	Adult-onset myasthenia gravis	Enrichment	CTLA4	2.00
45	Vogt-koyanagi-harada disease	Enrichment	FAS	2.00
46	Kaposi sarcoma	Enrichment	IL6	1.88
47	Immunodeficiency by defective expression of mhc class i	Enrichment	B2M	1.88
48	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	1.88
49	Amyloidosis, hereditary systemic 2	Enrichment	B2M	1.78
50	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	1.78
51	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.78
52	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	1.78
53	Atrial septal defect 1	Enrichment	TGFB2	1.70
54	Type 1 diabetes mellitus	Enrichment	IL6	1.70
55	Granulomatosis with polyangiitis	Enrichment	CTLA4	1.70
56	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10	1.70
57	Common variable immunodeficiency	Enrichment	CD40LG	1.64
58	Narcolepsy 1	Enrichment	TNFSF4	1.58
59	Lymphoma, non-hodgkin, familial	Enrichment	B2M	1.58
60	Rheumatoid arthritis	Enrichment	IL10	1.53
61	Inflammatory bowel disease 1	Enrichment	IL6	1.53
62	Marfan syndrome	Enrichment	TGFB2	1.49
63	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	TGFB3	1.41
64	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	TGFB3	1.41
65	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	TGFB3	1.34
66	Arteriovenous malformations of the brain	Enrichment	IL6	1.21
67	Ehlers-danlos syndrome	Enrichment	TGFB2	1.21
68	Myocardial infarction	Enrichment	TNFSF4	1.15
69	Severe covid-19	Enrichment	HLA-A	1.04
70	Type 2 diabetes mellitus	Enrichment	IL6	0.88

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

T cell modulation in pancreatic cancer

Pathway Network for T cell modulation in pancreatic cancer

Member Pathways for T cell modulation in pancreatic cancer

Pathways in the T cell modulation in pancreatic cancer SuperPath

Associated Genes for T cell modulation in pancreatic cancer

Associated Disorders for T cell modulation in pancreatic cancer

Disorders associated with T cell modulation in pancreatic cancer SuperPath

STRING Interaction Network for T cell modulation in pancreatic cancer

Sources for T cell modulation in pancreatic cancer