Tenofovir/Adefovir Pathway, Pharmacokinetics
Pathways in the Tenofovir/Adefovir Pathway, Pharmacokinetics SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Tenofovir/Adefovir Pathway, Pharmacokinetics | PharmGKB |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | ABCC4 | ATP Binding Cassette Subfamily C Member 4 (PEL Blood Group) | Protein Coding | 1 |
| 2 | NME1 | NME/NM23 Nucleoside Diphosphate Kinase 1 | Protein Coding | 1 |
| 3 | NME2 | NME/NM23 Nucleoside Diphosphate Kinase 2 | Protein Coding | 1 |
| 4 | AK2 | Adenylate Kinase 2 | Protein Coding | 1 |
| 5 | SLC22A6 | Solute Carrier Family 22 Member 6 | Protein Coding | 1 |
| 6 | SLC26A8 | Solute Carrier Family 26 Member 8 | Protein Coding | 1 |
| 7 | ABCC10 | ATP Binding Cassette Subfamily C Member 10 | Protein Coding | 1 |
| 8 | AK4 | Adenylate Kinase 4 | Protein Coding | 1 |
Disorders associated with Tenofovir/Adefovir Pathway, Pharmacokinetics SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Spermatogenic failure 3 | Enrichment | SLC26A8 | 3.23 |
| 2 | Immunoerythromyeloid hypoplasia | Enrichment | AK2 | 2.93 |
| 3 | Reticular dysgenesis | Enrichment | AK2 | 2.93 |
| 4 | Non-syndromic male infertility due to sperm motility disorder | Enrichment | SLC26A8 | 1.87 |
| 5 | Severe combined immunodeficiency | Enrichment | AK2 | 1.71 |
