TET1,2,3 and TDG demethylate DNA

No Pathway Network information available for TET1,2,3 and TDG demethylate DNA

#	Name	Source	Genes
1	TET1,2,3 and TDG demethylate DNA	Reactome	TDG TET1 TET2 TET3

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TET3	Tet Methylcytosine Dioxygenase 3	Protein Coding	1
2	TET2	Tet Methylcytosine Dioxygenase 2	Protein Coding	1
3	TDG	Thymine DNA Glycosylase	Protein Coding	1
4	TET1	Tet Methylcytosine Dioxygenase 1	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Myeloma, multiple	Enrichment	TET2, TET3	4.00
2	Tet3-related beck-fahrner syndrome	Enrichment	TET3	3.53
3	Beck-fahrner syndrome	Enrichment	TET3	3.53
4	Myelodysplastic neoplasm with increased blasts type 2	Enrichment	TET2	3.53
5	Myelodysplastic neoplasm with increased blasts type 1	Enrichment	TET2	3.53
6	Myelodysplastic neoplasm with low blasts	Enrichment	TET2	3.53
7	Immunodeficiency 75 with lymphoproliferation	Enrichment	TET2	3.23
8	Myelodysplastic syndrome with ring sideroblasts	Enrichment	TET2	3.05
9	Systemic mastocytosis with associated hematologic neoplasm	Enrichment	TET2	2.93
10	Aggressive systemic mastocytosis	Enrichment	TET2	2.83
11	Myelofibrosis	Enrichment	TET2	2.69
12	Third-degree atrioventricular block	Enrichment	TET2	2.69
13	Essential thrombocythemia	Enrichment	TET2	2.69
14	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	TET2	2.58
15	Myelodysplastic syndrome	Enrichment	TET2	2.49
16	Leukemia, acute myeloid	Enrichment	TET2	1.93

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for TET1,2,3 and TDG demethylate DNA