TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition

No Pathway Network information available for TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition

Pathways in the TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition SuperPath

#	Name	Source	Genes
1	TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition	WikiPathways	AKT1 CDH16 CDH6 FN1 ID1 MAPK1 RUNX2 SMAD2 SMAD3 SMAD4 SNAI1 SNAI2 TNC VIM (see all 14) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RUNX2	RUNX Family Transcription Factor 2	Protein Coding	1
2	VIM	Vimentin	Protein Coding	1
3	SNAI1	Snail Family Transcriptional Repressor 1	Protein Coding	1
4	SNAI2	Snail Family Transcriptional Repressor 2	Protein Coding	1
5	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
6	SMAD4	SMAD Family Member 4	Protein Coding	1
7	SMAD3	SMAD Family Member 3	Protein Coding	1
8	SMAD2	SMAD Family Member 2	Protein Coding	1
9	ID1	Inhibitor Of DNA Binding 1	Protein Coding	1
10	TNC	Tenascin C	Protein Coding	1
11	FN1	Fibronectin 1	Protein Coding	1
12	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
13	CDH6	Cadherin 6	Protein Coding	1
14	CDH16	Cadherin 16	Protein Coding	1

Disorders associated with TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SMAD2, SMAD3, SMAD4	4.95
2	Loeys-dietz syndrome	Enrichment	SMAD2, SMAD3	4.45
3	Nephrotic syndrome	Enrichment	FN1, RUNX2	3.06
4	Proteus syndrome	Enrichment	AKT1	2.99
5	Deafness, autosomal dominant 56	Enrichment	TNC	2.99
6	Noonan syndrome 13	Enrichment	MAPK1	2.99
7	Cowden syndrome 6	Enrichment	AKT1	2.99
8	Loeys-dietz syndrome 6	Enrichment	SMAD2	2.99
9	Congenital heart defects, multiple types, 8, with or without heterotaxy	Enrichment	SMAD2	2.99
10	Heritable thoracic aortic disease	Enrichment	SMAD4	2.99
11	Premature aging	Enrichment	VIM	2.99
12	Metaphyseal dysplasia with maxillary hypoplasia with or without brachydactyly	Enrichment	RUNX2	2.69
13	Myhre syndrome	Enrichment	SMAD4	2.69
14	Spondyloepimetaphyseal dysplasia, strudwick type	Enrichment	FN1	2.69
15	Spondylometaphyseal dysplasia, corner fracture type	Enrichment	FN1	2.69
16	Piebald trait	Enrichment	SNAI2	2.69
17	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	2.69
18	Loeys-dietz syndrome 3	Enrichment	SMAD3	2.69
19	Cataract 30	Enrichment	VIM	2.69
20	Cleidocranial dysplasia 1	Enrichment	RUNX2	2.51
21	Juvenile polyposis syndrome	Enrichment	SMAD4	2.51
22	Glomerulopathy with fibronectin deposits 2	Enrichment	FN1	2.51
23	Loeys-dietz syndrome 1	Enrichment	SMAD2	2.51
24	Cleidocranial dysplasia	Enrichment	RUNX2	2.51
25	Colorectal cancer	Enrichment	AKT1, SMAD4	2.45
26	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	2.38
27	Aortic aneurysm	Enrichment	SMAD3	2.38
28	Histiocytoid hemangioma	Enrichment	VIM	2.29
29	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	SMAD4	2.29
30	Breast adenocarcinoma	Enrichment	AKT1	2.21
31	Waardenburg syndrome, type 2e	Enrichment	SNAI2	2.14
32	Gallbladder cancer	Enrichment	SMAD4	2.14
33	Hereditary hemorrhagic telangiectasia	Enrichment	SMAD4	2.14
34	Cowden syndrome	Enrichment	AKT1	2.03
35	Familial thoracic aortic aneurysm and dissection	Enrichment	SMAD3	2.03
36	Cataract 30, multiple types	Enrichment	VIM	1.99
37	Specific learning disability	Enrichment	MAPK1	1.95
38	Meningioma	Enrichment	AKT1	1.91
39	Aortic aneurysm, familial thoracic 1	Enrichment	SMAD3	1.84
40	Heart, malformation of	Enrichment	MAPK1	1.73
41	Ehlers-danlos syndrome	Enrichment	SMAD3	1.71
42	Pancreatic cancer	Enrichment	SMAD4	1.59
43	Connective tissue disease	Enrichment	SMAD3	1.49
44	Gastric cancer	Enrichment	SMAD4	1.36
45	Hereditary breast carcinoma	Enrichment	AKT1	1.35
46	Thrombocytopenia	Enrichment	SMAD4	1.31
47	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	TNC	1.28
48	Breast cancer	Enrichment	AKT1	1.13
49	Ovarian cancer	Enrichment	AKT1	1.00
50	Microcephaly	Enrichment	MAPK1	0.92
51	Inherited cancer-predisposing syndrome	Enrichment	SMAD4	0.89

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition

Pathway Network for TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition

Member Pathways for TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition

Pathways in the TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition SuperPath

Associated Genes for TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition

Associated Disorders for TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition

Disorders associated with TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition SuperPath

STRING Interaction Network for TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition

Sources for TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition