Thromboxane signalling through TP receptor

Pathway network for the Thromboxane signalling through TP receptor SuperPath

Sources:

Reactome
GeneGo (Thomson Reuters)

Pathways in the Thromboxane signalling through TP receptor SuperPath

#	Name	Source	Genes
1	Thromboxane signalling through TP receptor	Reactome	AAMP GNA11 GNA13 GNA14 GNA15 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 TBXA2R (see all 24) (see less)
2	Development Angiotensin signaling via beta-Arrestin	GeneGo (Thomson Reuters)	AGT AGTR1 AP2B1 ARRB1 ARRB2 CALM1 CALM2 CALM3 CLTA CLTB CLTC GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GRK2 GRK3 GRK5 GRK6 MAP2K1 MAP2K4 MAP3K5 MAPK1 MAPK10 MAPK3 MDM2 PRKCA PRKCB PRKCG RAF1 SRC UBA52 UBB UBC (see all 47) (see less)
3	Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Reactome	CCT2 CCT3 CCT4 CCT5 CCT6A CCT6B CCT7 CCT8 CSNK2A1 CSNK2A2 CSNK2B GNA11 GNA14 GNA15 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 PDCL RGS11 RGS6 RGS7 RGS9 TCP1 (see all 38) (see less)
4	Signal amplification	Reactome	AAMP GNA11 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAQ GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 MAPK14 P2RY1 P2RY12 PLA2G4A SRC TBXA2R (see all 33) (see less)
5	Thrombin signalling through proteinase activated receptors (PARs)	Reactome	ARRB1 ARRB2 F2 F2R F2RL2 F2RL3 GNA11 GNA12 GNA13 GNA14 GNA15 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 MAPK1 MAPK3 SRC (see all 32) (see less)
6	Adrenaline,noradrenaline inhibits insulin secretion	Reactome	ADCY5 ADCY6 ADRA2A ADRA2C CACNA1C CACNA1D CACNA2D2 CACNB2 CACNB3 GNAI1 GNAI2 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 (see all 28) (see less)
7	ADP signalling through P2Y purinoceptor 1	Reactome	GNA11 GNA14 GNA15 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 MAPK14 P2RY1 PLA2G4A SRC (see all 25) (see less)
8	G-protein activation	Reactome	GNA11 GNA14 GNA15 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 OPRM1 PDYN POMC (see all 24) (see less)
9	ADP signalling through P2Y purinoceptor 12	Reactome	GNAI1 GNAI2 GNAI3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 P2RY12 (see all 22) (see less)

Gene overlap in member pathways for Thromboxane signalling through TP receptor SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	GNB5	G Protein Subunit Beta 5	Protein Coding	9
2	GNB1	G Protein Subunit Beta 1	Protein Coding	9
3	GNB2	G Protein Subunit Beta 2	Protein Coding	9
4	GNB3	G Protein Subunit Beta 3	Protein Coding	9
5	GNG3	G Protein Subunit Gamma 3	Protein Coding	9
6	GNG4	G Protein Subunit Gamma 4	Protein Coding	9
7	GNG5	G Protein Subunit Gamma 5	Protein Coding	9
8	GNG7	G Protein Subunit Gamma 7	Protein Coding	9
9	GNG10	G Protein Subunit Gamma 10	Protein Coding	9
10	GNG11	G Protein Subunit Gamma 11	Protein Coding	9
11	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	9
12	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	9
13	GNG13	G Protein Subunit Gamma 13	Protein Coding	9
14	GNG2	G Protein Subunit Gamma 2	Protein Coding	9
15	GNG12	G Protein Subunit Gamma 12	Protein Coding	9
16	GNB4	G Protein Subunit Beta 4	Protein Coding	9
17	GNG8	G Protein Subunit Gamma 8	Protein Coding	9
18	GNA11	G Protein Subunit Alpha 11	Protein Coding	6
19	GNA15	G Protein Subunit Alpha 15	Protein Coding	6
20	GNAQ	G Protein Subunit Alpha Q	Protein Coding	6
21	GNA14	G Protein Subunit Alpha 14	Protein Coding	6
22	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	4
23	GNA13	G Protein Subunit Alpha 13	Protein Coding	3
24	GNAI1	G Protein Subunit Alpha I1	Protein Coding	3
25	GNAI2	G Protein Subunit Alpha I2	Protein Coding	3
26	AAMP	Angio Associated Migratory Cell Protein	Protein Coding	2
27	TBXA2R	Thromboxane A2 Receptor	Protein Coding	2
28	ARRB1	Arrestin Beta 1	Protein Coding	2
29	ARRB2	Arrestin Beta 2	Protein Coding	2
30	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	2
31	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	2
32	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	2
33	GNAI3	G Protein Subunit Alpha I3	Protein Coding	2
34	GNAT3	G Protein Subunit Alpha Transducin 3	Protein Coding	2
35	P2RY1	Purinergic Receptor P2Y1	Protein Coding	2
36	PLA2G4A	Phospholipase A2 Group IVA	Protein Coding	2
37	P2RY12	Purinergic Receptor P2Y12	Protein Coding	2
38	GRK2	G Protein-Coupled Receptor Kinase 2	Protein Coding	1
39	GRK3	G Protein-Coupled Receptor Kinase 3	Protein Coding	1
40	AP2B1	Adaptor Related Protein Complex 2 Subunit Beta 1	Protein Coding	1
41	AGT	Angiotensinogen	Protein Coding	1
42	AGTR1	Angiotensin II Receptor Type 1	Protein Coding	1
43	CALM1	Calmodulin 1	Protein Coding	1
44	CALM2	Calmodulin 2	Protein Coding	1
45	CALM3	Calmodulin 3	Protein Coding	1
46	CLTA	Clathrin Light Chain A	Protein Coding	1
47	CLTB	Clathrin Light Chain B	Protein Coding	1
48	CLTC	Clathrin Heavy Chain	Protein Coding	1
49	GRK5	G Protein-Coupled Receptor Kinase 5	Protein Coding	1
50	GRK6	G Protein-Coupled Receptor Kinase 6	Protein Coding	1
51	MDM2	MDM2 Proto-Oncogene	Protein Coding	1
52	MAP3K5	Mitogen-Activated Protein Kinase Kinase Kinase 5	Protein Coding	1
53	PRKCA	Protein Kinase C Alpha	Protein Coding	1
54	PRKCB	Protein Kinase C Beta	Protein Coding	1
55	PRKCG	Protein Kinase C Gamma	Protein Coding	1
56	MAPK10	Mitogen-Activated Protein Kinase 10	Protein Coding	1
57	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
58	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
59	MAP2K4	Mitogen-Activated Protein Kinase Kinase 4	Protein Coding	1
60	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	1
61	UBB	Ubiquitin B	Protein Coding	1
62	UBC	Ubiquitin C	Protein Coding	1
63	CCT7	Chaperonin Containing TCP1 Subunit 7	Protein Coding	1
64	CCT4	Chaperonin Containing TCP1 Subunit 4	Protein Coding	1
65	CCT2	Chaperonin Containing TCP1 Subunit 2	Protein Coding	1
66	CCT6B	Chaperonin Containing TCP1 Subunit 6B	Protein Coding	1
67	CCT8	Chaperonin Containing TCP1 Subunit 8	Protein Coding	1
68	CSNK2A1	Casein Kinase 2 Alpha 1	Protein Coding	1
69	CSNK2A2	Casein Kinase 2 Alpha 2	Protein Coding	1
70	CSNK2B	Casein Kinase 2 Beta	Protein Coding	1
71	CCT5	Chaperonin Containing TCP1 Subunit 5	Protein Coding	1
72	PDCL	Phosducin Like	Protein Coding	1
73	RGS7	Regulator Of G Protein Signaling 7	Protein Coding	1
74	TCP1	T-Complex 1	Protein Coding	1
75	CCT3	Chaperonin Containing TCP1 Subunit 3	Protein Coding	1
76	RGS11	Regulator Of G Protein Signaling 11	Protein Coding	1
77	RGS9	Regulator Of G Protein Signaling 9	Protein Coding	1
78	CCT6A	Chaperonin Containing TCP1 Subunit 6A	Protein Coding	1
79	RGS6	Regulator Of G Protein Signaling 6	Protein Coding	1
80	F2	Coagulation Factor II, Thrombin	Protein Coding	1
81	F2R	Coagulation Factor II Thrombin Receptor	Protein Coding	1
82	F2RL2	Coagulation Factor II Thrombin Receptor Like 2	Protein Coding	1
83	GNA12	G Protein Subunit Alpha 12	Protein Coding	1
84	F2RL3	F2R Like Thrombin Or Trypsin Receptor 3	Protein Coding	1
85	ADCY5	Adenylate Cyclase 5	Protein Coding	1
86	ADCY6	Adenylate Cyclase 6	Protein Coding	1
87	ADRA2A	Adrenoceptor Alpha 2A	Protein Coding	1
88	ADRA2C	Adrenoceptor Alpha 2C	Protein Coding	1
89	CACNA1C	Calcium Voltage-Gated Channel Subunit Alpha1 C	Protein Coding	1
90	CACNA1D	Calcium Voltage-Gated Channel Subunit Alpha1 D	Protein Coding	1
91	CACNB2	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 2	Protein Coding	1
92	CACNB3	Calcium Voltage-Gated Channel Auxiliary Subunit Beta 3	Protein Coding	1
93	CACNA2D2	Calcium Voltage-Gated Channel Auxiliary Subunit Alpha2delta 2	Protein Coding	1
94	OPRM1	Opioid Receptor Mu 1	Protein Coding	1
95	PDYN	Prodynorphin	Protein Coding	1
96	POMC	Proopiomelanocortin	Protein Coding	1

Disorders associated with Thromboxane signalling through TP receptor SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Anastomosing haemangioma	Enrichment	GNA11, GNA14, GNAQ	8.31
2	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	5.67
3	Phakomatosis cesioflammea	Enrichment	GNA11, GNAQ	5.52
4	Hypertension, essential	Enrichment	AGT, AGTR1, GNB3	4.59
5	Capillary malformations, congenital	Enrichment	GNA11, GNAQ	4.52
6	Melanoma, uveal	Enrichment	GNA11, GNAQ	4.35
7	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3	3.83
8	Renal tubular dysgenesis	Enrichment	AGT, AGTR1	3.76
9	Noonan syndrome 3	Enrichment	CLTC, RAF1	3.61
10	Noonan syndrome and noonan-related syndrome	Enrichment	MAP2K1, RAF1	2.92
11	Brugada syndrome	Enrichment	CACNA1C, CACNB2	2.89
12	Ventricular tachycardia, familial	Enrichment	GNAI2	2.79
13	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	2.79
14	Neurodevelopmental disorder with hypotonia, impaired speech, and behavioral abnormalities	Enrichment	GNAI1	2.79
15	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	2.79
16	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	2.79
17	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	2.79
18	Sick sinus syndrome 4	Enrichment	GNB2	2.79
19	Hypocalciuric hypercalcemia, familial, type ii	Enrichment	GNA11	2.75
20	Sturge-weber syndrome	Enrichment	GNAQ	2.75
21	Bleeding disorder, platelet-type, 13	Enrichment	TBXA2R	2.75
22	Hypocalcemia, autosomal dominant 2	Enrichment	GNA11	2.75
23	Bleeding diathesis due to thromboxane synthesis deficiency	Enrichment	TBXA2R	2.75
24	Phakomatosis cesiomarmorata	Enrichment	GNA11	2.75
25	Kaposiform hemangioendothelioma	Enrichment	GNA14	2.75
26	Cytosolic phospholipase-a2 alpha deficiency associated bleeding disorder	Enrichment	PLA2G4A	2.73
27	Thrombocytopenia 6	Enrichment	SRC	2.73
28	Gastrointestinal ulceration, recurrent, with dysfunctional platelets	Enrichment	PLA2G4A	2.73
29	Cryptogenic multifocal ulcerous stenosing enteritis	Enrichment	PLA2G4A	2.73
30	Brugada syndrome 4	Enrichment	CACNB2	2.69
31	Dyskinesia with orofacial involvement, autosomal dominant	Enrichment	ADCY5	2.69
32	Neurodevelopmental disorder with hyperkinetic movements and dyskinesia	Enrichment	ADCY5	2.69
33	Primary aldosteronism, seizures, and neurologic abnormalities	Enrichment	CACNA1D	2.69
34	Dyskinesia with orofacial involvement, autosomal recessive	Enrichment	ADCY5	2.69
35	Brugada syndrome 3	Enrichment	CACNA1C	2.69
36	Sinoatrial node dysfunction and deafness	Enrichment	CACNA1D	2.69
37	Lipodystrophy, familial partial, type 8	Enrichment	ADRA2A	2.69
38	Atypical timothy syndrome	Enrichment	CACNA1C	2.69
39	Aldosterone-producing adenoma with seizures and neurological abnormalities	Enrichment	CACNA1D	2.69
40	Timothy syndrome type 2	Enrichment	CACNA1C	2.69
41	Timothy syndrome type 1	Enrichment	CACNA1C	2.69
42	Cacna1c-related disorders	Enrichment	CACNA1C	2.69
43	Prothrombin deficiency, congenital	Enrichment	F2	2.63
44	Noonan syndrome 13	Enrichment	MAPK1	2.63
45	Pregnancy loss, recurrent 2	Enrichment	F2	2.63
46	Prothrombin deficiency	Enrichment	F2	2.63
47	Intellectual developmental disorder with polymicrogyria and seizures	Enrichment	TCP1	2.55
48	Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive	Enrichment	CCT5	2.55
49	Autosomal recessive sensory neuropathy with spastic paraplegia	Enrichment	CCT5	2.55
50	Prolonged electroretinal response suppression 1	Enrichment	RGS9	2.55
51	Okur-chung neurodevelopmental syndrome	Enrichment	CSNK2A1	2.55
52	Craniodigital syndrome and intellectual disability syndrome	Enrichment	CSNK2B	2.55
53	Neurodevelopmental disorder with speech or visual impairment and brain hypomyelination	Enrichment	CCT3	2.55
54	Noonan syndrome 1	Enrichment	MAP2K1, RAF1	2.55
55	Cerebral palsy	Enrichment	CACNA1C, GNB1	2.54
56	Pituitary adenoma 4, acth-secreting	Enrichment	GNAI2	2.49
57	Bleeding disorder, platelet-type, 8	Enrichment	P2RY12	2.49
58	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	2.49
59	Hypopituitarism	Enrichment	GNAI2	2.49
60	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	2.49
61	Cerebral visual impairment	Enrichment	GNB1	2.49
62	Noonan syndrome 5	Enrichment	RAF1	2.46
63	Melorheostosis, isolated	Enrichment	MAP2K1	2.46
64	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.46
65	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.46
66	Accelerated tumor formation	Enrichment	MDM2	2.46
67	Lessel-kubisch syndrome	Enrichment	MDM2	2.46
68	Spinocerebellar ataxia 14	Enrichment	PRKCG	2.46
69	Melorheostosis	Enrichment	MAP2K1	2.46
70	Leopard syndrome 2	Enrichment	RAF1	2.46
71	Long qt syndrome 16	Enrichment	CALM3	2.46
72	Trigonitis	Enrichment	RAF1	2.46
73	Long qt syndrome 15	Enrichment	CALM2	2.46
74	Autism spectrum disorder	Enrichment	CSNK2A1, CSNK2B, GNB1	2.46
75	Cutis marmorata telangiectatica congenita	Enrichment	GNA11	2.45
76	Angioma, tufted	Enrichment	GNA14	2.45
77	Autosomal dominant hypocalcemia	Enrichment	GNA11	2.45
78	Spinocerebellar ataxia 23	Enrichment	PDYN	2.45
79	Rasopathy	Enrichment	MAP2K1, RAF1	2.44
80	Timothy syndrome	Enrichment	CACNA1C	2.38
81	Lethal congenital contracture syndrome 8	Enrichment	ADCY6	2.38
82	Long qt syndrome 8	Enrichment	CACNA1C	2.38
83	Congenital disorder of glycosylation, type iw, autosomal dominant	Enrichment	CACNA1D	2.38
84	Nizon-isidor syndrome	Enrichment	P2RY12	2.31
85	Long qt syndrome	Enrichment	CALM1, CALM2	2.29
86	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	GNA11	2.28
87	Obesity, early-onset, with adrenal insufficiency and red hair	Enrichment	POMC	2.28
88	Obesity due to pro-opiomelanocortin deficiency	Enrichment	POMC	2.28
89	Poirier-bienvenu neurodevelopmental syndrome	Enrichment	CSNK2B	2.25
90	Bradyopsia	Enrichment	RGS9	2.25
91	Thrombocytopenia	Enrichment	P2RY12, SRC	2.22
92	Neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures	Enrichment	CACNA1C	2.21
93	Hypomyelination neuropathy-arthrogryposis syndrome	Enrichment	ADCY6	2.21
94	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	2.19
95	Auriculocondylar syndrome 1	Enrichment	GNAI3	2.19
96	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	2.19
97	Achromatopsia 4	Enrichment	GNAI3	2.19
98	Familial sick sinus syndrome	Enrichment	GNB2	2.19
99	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	2.16
100	Long qt syndrome 14	Enrichment	CALM1	2.16
101	Submucosal cleft palate	Enrichment	UBB	2.16
102	Cleft hard palate	Enrichment	UBB	2.16
103	Cerebral sinovenous thrombosis	Enrichment	F2	2.15
104	Chorea, benign hereditary	Enrichment	ADCY5	2.08
105	Ventricular fibrillation, paroxysmal familial, 1	Enrichment	CACNA1C	2.08
106	Cerebellar atrophy with seizures and variable developmental delay	Enrichment	CACNA2D2	2.08
107	Prognathism, mandibular	Enrichment	CSNK2B	2.08
108	Autosomal dominant non-syndromic intellectual disability	Enrichment	CSNK2B, GNB1	2.07
109	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	2.03
110	Heart conduction disease	Enrichment	CACNA1C	1.99
111	Uvula, bifid	Enrichment	UBB	1.98
112	Langerhans cell histiocytosis	Enrichment	MAP2K1	1.98
113	Cleft soft palate	Enrichment	UBB	1.98
114	Intellectual developmental disorder, autosomal dominant 56	Enrichment	CLTC	1.98
115	Dedifferentiated liposarcoma	Enrichment	MDM2	1.98
116	Well-differentiated liposarcoma	Enrichment	MDM2	1.98
117	Klippel-trenaunay-weber syndrome	Enrichment	GNAQ	1.98
118	Enophthalmos	Enrichment	CSNK2B	1.95
119	Syndactyly	Enrichment	CSNK2B	1.95
120	Myelofibrosis	Enrichment	SRC	1.89
121	Hypothyroidism	Enrichment	GNB1	1.89
122	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K1	1.86
123	Cardiofaciocutaneous syndrome	Enrichment	MAP2K1	1.86
124	Hereditary ataxia	Enrichment	PRKCG	1.86
125	Neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 1	Enrichment	CLTC	1.86
126	Noonan syndrome with multiple lentigines	Enrichment	RAF1	1.86
127	Thrombophilia due to thrombin defect	Enrichment	F2	1.79
128	Leukemia, acute lymphoblastic	Enrichment	GNB1	1.75
129	Myelodysplastic syndrome	Enrichment	GNB1	1.75
130	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	CACNA1C	1.73
131	Li-fraumeni syndrome	Enrichment	MDM2	1.69
132	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	1.69
133	Inflammatory myofibroblastic tumor	Enrichment	CLTC	1.69
134	Stroke, ischemic	Enrichment	F2	1.63
135	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1	1.62
136	Renal cell carcinoma with mit translocations	Enrichment	CLTC	1.62
137	Pilomyxoid astrocytoma	Enrichment	RAF1	1.62
138	Cardiac conduction defect	Enrichment	CACNA1C	1.61
139	Osteoporosis	Enrichment	SRC	1.59
140	Specific learning disability	Enrichment	MAPK1	1.59
141	Complex neurodevelopmental disorder	Enrichment	CACNA1C, GNB2	1.57
142	Cleft palate, isolated	Enrichment	GNB1	1.56
143	Melanocytic nevus syndrome, congenital	Enrichment	RAF1	1.56
144	Lennox-gastaut syndrome	Enrichment	MAPK10	1.56
145	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	1.56
146	Leber plus disease	Enrichment	CCT2, RGS9	1.54
147	Arteriovenous malformation	Enrichment	MAP2K1	1.51
148	Microcephaly	Enrichment	GNB1, MAPK1	1.47
149	Myopathy, x-linked, with excessive autophagy	Enrichment	MAP2K1	1.47
150	Attention deficit-hyperactivity disorder	Enrichment	GNB5	1.45
151	Congenital stationary night blindness	Enrichment	GNB3	1.44
152	Lung non-small cell carcinoma	Enrichment	MAP2K1	1.43
153	Heart, malformation of	Enrichment	MAPK1	1.38
154	Strabismus	Enrichment	GNB1	1.37
155	Cardiomyopathy, familial hypertrophic, 1	Enrichment	CACNA1C	1.31
156	Dystonia	Enrichment	GNB1	1.26
157	Sudden infant death syndrome	Enrichment	CALM2	1.24
158	Myocardial infarction	Enrichment	CCT7	1.22
159	Developmental and epileptic encephalopathy	Enrichment	CACNA2D2	1.14
160	Jeune thoracic dystrophy	Enrichment	GRK2	1.08
161	Body mass index quantitative trait locus 11	Enrichment	POMC	1.07
162	Asphyxiating thoracic dystrophy	Enrichment	GRK2	1.03
163	Short-rib thoracic dysplasia 1 with or without polydactyly	Enrichment	GRK2	0.97
164	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.97
165	Left ventricular noncompaction	Enrichment	RAF1	0.94
166	Breast cancer	Enrichment	GNG3	0.94
167	Colorectal cancer	Enrichment	SRC	0.83
168	Congenital nervous system abnormality	Enrichment	GNB5	0.80
169	Nervous system disease	Enrichment	GNB5	0.80
170	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.77
171	Undetermined early-onset epileptic encephalopathy	Enrichment	CLTC	0.75
172	Dilated cardiomyopathy	Enrichment	RAF1	0.61
173	Hereditary retinal dystrophy	Enrichment	RGS9	0.25
174	Fundus dystrophy	Enrichment	RGS9	0.25

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Thromboxane signalling through TP receptor

Pathway Network for Thromboxane signalling through TP receptor

Pathway network for the Thromboxane signalling through TP receptor SuperPath

Member Pathways for Thromboxane signalling through TP receptor

Pathways in the Thromboxane signalling through TP receptor SuperPath

Gene overlap in member pathways for Thromboxane signalling through TP receptor SuperPath

Associated Genes for Thromboxane signalling through TP receptor

Associated Disorders for Thromboxane signalling through TP receptor

Disorders associated with Thromboxane signalling through TP receptor SuperPath

STRING Interaction Network for Thromboxane signalling through TP receptor

Sources for Thromboxane signalling through TP receptor